Some Bence-Jones proteins enter cultured renal tubular cells, reach nuclei and induce cell death

Immunology

Volumn 98, Issue 4, 1999, Pages 584-589

  Matsuura, K ^a,d   Ikoma, S ^a   Watanabe, M ^a   Togawa, A ^b   Sinohara, H ^c  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^c KINKI UNIVERSITY   (Japan)

^d UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDASE; BENCE JONES PROTEIN; DEOXYRIBONUCLEASE; DNA FRAGMENT;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL DEATH; CYTOTOXICITY; DISEASE COURSE; ENZYME ACTIVITY; HUMAN; KIDNEY TUBULE CELL; MULTIPLE MYELOMA; NONHUMAN; PRIORITY JOURNAL;

AMIDOHYDROLASES; ANIMALS; ANTIBODIES, ANTINUCLEAR; BENCE JONES PROTEIN; CELL DEATH; CELL NUCLEUS; CELLS, CULTURED; DEOXYRIBONUCLEASES; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IN SITU NICK-END LABELING; KIDNEY TUBULES; MULTIPLE MYELOMA; SWINE;

EID: 0033432885     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1999.00898.x     Document Type: Article

References (27)

1. 1. PAUL S. (1996) Natural catalytic antibodies. Mol Biotechnol 5, 197.
2. 2. PAUL S. (1998) Antibody catalysis. In: Contemporary Immunology: Autoimmune Diseases (ed. P. PAUL), p. 221. Humana Press, Totowa, NJ.
3. L fragment. J Biol Chem 270, 15257.
4. 4. LI L., PAUL S., TYUTYULKOVA S. et al. (1995) Catalytic activity of anti-thyroglobulin antibodies. J Immunol 154, 3328.
5. 5. SHUSTER A.M., GOLOLOBOV G.V., KVASHUK O.A. et al. (1992) DNA hydrolyzing autoantibodies. Science 256, 665.
6. 6. MATSUURA K., YAMAMOTO K. & SINOHARA H. (1994) Amidase activity of human Bence Jones proteins. Biochem Biophys Res Commun 204, 57.
7. 7. MATSUURA K. & SINOHARA H. (1996) Catalytic cleavage of vasopressin by human Bence Jones proteins at the arginylglycinamide bond. Biol Chem 377, 587.
8. 8. SINOHARA H. & MATSUURA K. (1998) Is catalytic activity of Bence Jones proteins an autoimmune effector mechanism in multiple myeloma? In: Contemporary Immunology: Autoimmune Diseases (ed. P. PAUL), p. 235. Humana Press, Totowa, NJ.
9. 9. KOHLER H. & PAUL S. (1998) Superantibody activities: new players in innate and adaptive immune responses. Immunol Today 19, 221.
10. 10. MATSUURA K., IKOMA S., YOSHIDA K. & SINOHARA H. (1998) DNA-hydrolyzing activity of Bence Jones proteins. Biochem Biophys Res Commun 243, 719.
11. 11. YANASE K., SMITH R.M., CIZMAN B. et al. (1994) A subgroup of murine monoclonal anti-deoxyribonucleic acid antibodies traverse the cytoplasm and enter the nucleus in a time- and temperature-dependent manner. Lab Invest 71, 52.
12. 12. VLAHAKOS D., FOSTER M.H., UCCI A.A. et al. (1992) Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation in vivo. J Am Soc Nephrol 2, 1345.
13. 13. MOSMANN T. (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65, 55.
14. 14. SIGNHAL P.C., SHARMA P., SANWAL V. et al (1998) Morphine modulates proliferation of kidney fibroblasts. Kidney Int 53, 350.
15. 15. MORI C., NAKAMURA N., OKAMOTO Y. et al (1994) Cytochemical identification of programmed cell death in the fusing fetal mouse palate by specific labelling of DNA fragmentation. Anat Embryol 190, 21.
16. 16. GAVRIELI Y., SHERMAN Y. & BEN-SASSON A. (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 19, 493.
17. 17. SELLINS K.S. & COHEN J.J. (1987) Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes. J Immunol 139, 3199.
18. 18. CHENG H. & RUKICK M.J. (1991) A membrane blotting method for following the time course of protein radioiodination background references using IODO-BEADS. Anal Biochem 198, 191.
19. 19. YAMAMOTO K., SUZUKI Y. & SINOHARA H. (1988) Synthesis of contrapsin and α-1-antiproteinase in inflamed and tumor-bearing mice. Biochem Int 16, 921.
20. 20. SELBY P. &GORE M. (1994) Myeloma and other plasma cell malignancies. In: Oxford Textbook of Oncology (eds M. PECKHAM, H. PINEGO & U. VERONESI), Vol 1, p. 852. Oxford University Press, Oxford.
21. 21. YANASE K., SMITH R.M., PUCCETTI A. et al (1997) Receptormediated cellular entry of nuclear localizing anti-DNA antibodies via myosin I. J Clin Invest 100, 25.
22. 22. YONEDA Y. (1997) How proteins are transported from cytoplasm to the nucleus. J Biochem 121, 811.
23. 23. GORLICH D. (1997) Nuclear protein import. Curr Opin Cell Biol 9, 412.
24. 24. FOSTER M.H., KIEBER-EMMONS T., OHLIGER M. & MADAIO M.P. (1994) Molecular and structural analysis of nuclear localizing anti-DNA lupus antibodies. Immunol Res 13, 172.
25. 25. PANDEY S., WALKER O.R. & SIKORSKA M. (1997) Identification of a novel 97 kDa endonuclease capable of internucleosomal DNA cleavage. Biochemistry 28, 711.
26. 26. SHIOKAWA D., OHYAMA H., YAMADA T. & TANUMA S. (1997) Purification and properties of DNases from apoptotic rat thymocytes. Biochem J 326, 675.
27. 27. ENARI M., SAKAHIRA H., YOKOYAMA H. et al. (1998) A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391, 43.