메뉴 건너뛰기




Volumn 26, Issue 12, 1999, Pages 1020-1025

Potential use of genetically modified pigs as organ donors for transplantation into humans

Author keywords

Complement; Hyperacute rejection; Transgenic; Xenotransplantation

Indexed keywords

REGULATOR PROTEIN;

EID: 0033431784     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.1999.03185.x     Document Type: Conference Paper
Times cited : (20)

References (48)
  • 1
    • 0008971108 scopus 로고    scopus 로고
    • on-line
    • 1. United Network for organ Sharing 1999 (on-line). http://www.unos.org
    • (1999)
  • 3
    • 0026500690 scopus 로고
    • The potential supply of organ donors: An assessment of the efficiency of organ procurement efforts in the United States
    • 3. Evans RW, Orians CE, Ascher NL. The potential supply of organ donors: An assessment of the efficiency of organ procurement efforts in the United States. JAMA 1992; 267: 239-46.
    • (1992) JAMA , vol.267 , pp. 239-246
    • Evans, R.W.1    Orians, C.E.2    Ascher, N.L.3
  • 5
    • 0023950859 scopus 로고
    • Effects of cyclosporine and antibody adsorption on pig cardiac xenograft survival in the baboon
    • 5. Cooper DKC, Human PA, Lexer G et al. Effects of cyclosporine and antibody adsorption on pig cardiac xenograft survival in the baboon. J. Heart Transplant. 1988; 7: 238-46.
    • (1988) J. Heart Transplant. , vol.7 , pp. 238-246
    • Cooper, D.K.C.1    Human, P.A.2    Lexer, G.3
  • 7
    • 0029905427 scopus 로고    scopus 로고
    • Inhibition of anti-gal IgG binding to porcine endothelial cells by synthetic oligosaccharides
    • 7. Galili U, Matta KL. Inhibition of anti-gal IgG binding to porcine endothelial cells by synthetic oligosaccharides. Transplantation 1996; 62: 256-62.
    • (1996) Transplantation , vol.62 , pp. 256-262
    • Galili, U.1    Matta, K.L.2
  • 8
    • 0026623093 scopus 로고
    • Identification of carbohydrate structures which bind human anti-porcine antibodies: Implications for discordant grafting in man
    • 8. Good H, Cooper DKC, Malcolm AJK et al. Identification of carbohydrate structures which bind human anti-porcine antibodies: Implications for discordant grafting in man. Transplant. Proc. 1992; 24: 559-62.
    • (1992) Transplant. Proc. , vol.24 , pp. 559-562
    • Good, H.1    Cooper, D.K.C.2    Malcolm, A.J.K.3
  • 9
    • 0028805535 scopus 로고
    • Enzymatic removal of alphagalactosyl epitopes from porcine endothelial cells diminishes the cytotoxic effect of natural antibodies
    • 9. LaVecchio JA, Dunne AD, Edge ASB. Enzymatic removal of alphagalactosyl epitopes from porcine endothelial cells diminishes the cytotoxic effect of natural antibodies. Transplantation 1995; 60: 841-7.
    • (1995) Transplantation , vol.60 , pp. 841-847
    • LaVecchio, J.A.1    Dunne, A.D.2    Edge, A.S.B.3
  • 10
    • 0030716263 scopus 로고    scopus 로고
    • The role of natural antiGalα1-3Gal antibodies in hyperacute rejection of pig-to-baboon cardiac xenotransplants
    • 10. Lin SS, Kooyman DL, Daniels LJ et al. The role of natural antiGalα1-3Gal antibodies in hyperacute rejection of pig-to-baboon cardiac xenotransplants. Transplant. Immunol. 1997; 5: 212-18.
    • (1997) Transplant. Immunol. , vol.5 , pp. 212-218
    • Lin, S.S.1    Kooyman, D.L.2    Daniels, L.J.3
  • 11
    • 0028218891 scopus 로고
    • Protection of pig kidney (PK15) cells from the cytotoxic effect of anti-pig antibodies by α-galactosyl oligosaccharides
    • 11. Neethling FA, Koren E, Ye Y et al. Protection of pig kidney (PK15) cells from the cytotoxic effect of anti-pig antibodies by α-galactosyl oligosaccharides. Transplantation 1994; 57: 959-63.
    • (1994) Transplantation , vol.57 , pp. 959-963
    • Neethling, F.A.1    Koren, E.2    Ye, Y.3
  • 13
    • 2442758069 scopus 로고    scopus 로고
    • In vivo immunoadsorption of antipig antibodies in baboons using a specific Galα 1-3Gal column
    • 13. Taniguchi S, Neethling FA, Korchagina EY et al. In vivo immunoadsorption of antipig antibodies in baboons using a specific Galα 1-3Gal column. Transplantation 1998; 62: 1379-84.
    • (1998) Transplantation , vol.62 , pp. 1379-1384
    • Taniguchi, S.1    Neethling, F.A.2    Korchagina, E.Y.3
  • 14
    • 0029996878 scopus 로고    scopus 로고
    • Removal of terminal α-galactosyl residues from xenogeneic porcine endothelial cells
    • 14. Watier H, Guillaumin J-M, Piller F et al. Removal of terminal α-galactosyl residues from xenogeneic porcine endothelial cells. Transplantation 1996; 62: 105-13.
    • (1996) Transplantation , vol.62 , pp. 105-113
    • Watier, H.1    Guillaumin, J.-M.2    Piller, F.3
  • 15
    • 0028045535 scopus 로고
    • Characterization of porcine endothelial cell determinants recognized by human natural antibodies
    • 15. Collins BH, Parker W, Platt JL. Characterization of porcine endothelial cell determinants recognized by human natural antibodies. Xenotransplantation 1994; 1: 36-46.
    • (1994) Xenotransplantation , vol.1 , pp. 36-46
    • Collins, B.H.1    Parker, W.2    Platt, J.L.3
  • 16
    • 0000665022 scopus 로고
    • Evolutionary relationship between the natural anti-Gal antibody and the Galα 1-3Gal epitope in primates
    • 16. Galili U, Clark MR, Shohet SB, Buehler J, Macher BA. Evolutionary relationship between the natural anti-Gal antibody and the Galα 1-3Gal epitope in primates. Proc. Natl Acad. Sci. USA 1987; 84: 1369-73.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 1369-1373
    • Galili, U.1    Clark, M.R.2    Shohet, S.B.3    Buehler, J.4    Macher, B.A.5
  • 17
    • 0024297335 scopus 로고
    • Man, apes and old world monkeys differ from other mammals in the expression of α-galactosyl epitopes on nucleated cells
    • 17. Galili U, Shohet SB, Kobrin E, Stults CL, Macher BA. Man, apes and old world monkeys differ from other mammals in the expression of α-galactosyl epitopes on nucleated cells. J. Biol. Chem. 1988; 263: 17 755-62.
    • (1988) J. Biol. Chem. , vol.263 , pp. 17755-17762
    • Galili, U.1    Shohet, S.B.2    Kobrin, E.3    Stults, C.L.4    Macher, B.A.5
  • 18
    • 0023950850 scopus 로고
    • Interaction between human natural anti-alpha-galactosyl immunoglobulin G and bacteria of the human flora
    • 18. Galili U, Mandrell RE, Hamadeh RM, Shohet SB, Griffiss JM. Interaction between human natural anti-alpha-galactosyl immunoglobulin G and bacteria of the human flora. Infect. Immun. 1988; 56: 1730-7.
    • (1988) Infect. Immun. , vol.56 , pp. 1730-1737
    • Galili, U.1    Mandrell, R.E.2    Hamadeh, R.M.3    Shohet, S.B.4    Griffiss, J.M.5
  • 19
    • 0029876177 scopus 로고    scopus 로고
    • Isohemagglutinins and xenoreactive antibodies are members of a distinct family of natural antibodies
    • 19. Parker W, Lundberg-Swanson KL, Holzknecht ZE et al. Isohemagglutinins and xenoreactive antibodies are members of a distinct family of natural antibodies. Hum. Immunol. 1996; 45: 94-104.
    • (1996) Hum. Immunol. , vol.45 , pp. 94-104
    • Parker, W.1    Lundberg-Swanson, K.L.2    Holzknecht, Z.E.3
  • 20
    • 0023205314 scopus 로고
    • Separation of self from non-self in the complement system
    • 20. Atkinson JP, Fairies T. Separation of self from non-self in the complement system. Immunol. Today 1987; 8: 212-15.
    • (1987) Immunol. Today , vol.8 , pp. 212-215
    • Atkinson, J.P.1    Fairies, T.2
  • 21
    • 0024211465 scopus 로고
    • The mechanism of discordant xenograft rejection
    • 21. Miyagawa S, Hirose H, Shirakura R et al. The mechanism of discordant xenograft rejection. Transplantation 1988; 46: 825-30.
    • (1988) Transplantation , vol.46 , pp. 825-830
    • Miyagawa, S.1    Hirose, H.2    Shirakura, R.3
  • 22
    • 0025225361 scopus 로고
    • Transplantation of discordant xenografts: A review of progress
    • 22. Platt JL, Vercellotti GM, Dalmasso AP et al. Transplantation of discordant xenografts: A review of progress. Immunol. Today 1990; 11: 450-7.
    • (1990) Immunol. Today , vol.11 , pp. 450-457
    • Platt, J.L.1    Vercellotti, G.M.2    Dalmasso, A.P.3
  • 23
    • 0021930664 scopus 로고
    • Production of transgenic rabbits, sheep and pigs by microinjection
    • 23. Hammer RE, Pursel VG, Rexroad Jr CE et al. Production of transgenic rabbits, sheep and pigs by microinjection. Nature 1985; 315: 680-3.
    • (1985) Nature , vol.315 , pp. 680-683
    • Hammer, R.E.1    Pursel, V.G.2    Rexroad C.E., Jr.3
  • 24
    • 0028364884 scopus 로고
    • Transgenic swine as a recombinant production system for human hemoglobin
    • 24. Logan JS, Martin M. Transgenic swine as a recombinant production system for human hemoglobin. Methods Enzymol. 1993; 231: 435-45.
    • (1993) Methods Enzymol. , vol.231 , pp. 435-445
    • Logan, J.S.1    Martin, M.2
  • 25
    • 16044372786 scopus 로고    scopus 로고
    • Heterochromatin effects on the frequency and duration of LCR-mediatcd gene transcription
    • 25. Milot E, Strouboulis J, Trimborn T et al. Heterochromatin effects on the frequency and duration of LCR-mediatcd gene transcription. Cell 1996; 87: 105-14.
    • (1996) Cell , vol.87 , pp. 105-114
    • Milot, E.1    Strouboulis, J.2    Trimborn, T.3
  • 26
    • 0029001840 scopus 로고
    • In vivo transfer of GPI linked complement restriction factors from erythrocytes to the endothelium
    • 26. Kooyman DL, Byrne GW, McClellan S et al. In vivo transfer of GPI linked complement restriction factors from erythrocytes to the endothelium. Science 1995; 269: 89-92.
    • (1995) Science , vol.269 , pp. 89-92
    • Kooyman, D.L.1    Byrne, G.W.2    McClellan, S.3
  • 27
    • 0029033071 scopus 로고
    • Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury
    • 27. McCurry KR, Kooyman DL, Alvarado CG et al. Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury. Nature Med. 1995; 1: 423-7.
    • (1995) Nature Med. , vol.1 , pp. 423-427
    • McCurry, K.R.1    Kooyman, D.L.2    Alvarado, C.G.3
  • 28
    • 0031014159 scopus 로고    scopus 로고
    • Transgenic pigs expressing human CD59 and decay-accelerating factor produce an intrinsic barrier to complement-mediated damage
    • 28. Byrne GW, McCurry KR, Martin MJ, McClellan SM, Platt JL, Logan JS. Transgenic pigs expressing human CD59 and decay-accelerating factor produce an intrinsic barrier to complement-mediated damage. Transplantation 1997; 63: 149-55.
    • (1997) Transplantation , vol.63 , pp. 149-155
    • Byrne, G.W.1    McCurry, K.R.2    Martin, M.J.3    McClellan, S.M.4    Platt, J.L.5    Logan, J.S.6
  • 29
    • 0029922027 scopus 로고    scopus 로고
    • High-level tissue specific expression of human CD59, MCP, and DAF proteins from genomic clones in transgenic mice
    • 29. Oldham ER, Velardo MA, Platt JL, Logan JS, Diamond L. High-level tissue specific expression of human CD59, MCP, and DAF proteins from genomic clones in transgenic mice. Transplant. Proc. 1996; 28: 693.
    • (1996) Transplant. Proc. , vol.28 , pp. 693
    • Oldham, E.R.1    Velardo, M.A.2    Platt, J.L.3    Logan, J.S.4    Diamond, L.5
  • 30
    • 0344776056 scopus 로고    scopus 로고
    • Expression of human complement regulatory proteins CD59 and decay accelerating factor (DAF) prolongs graft survival and physiological function in pig-to-baboon kidney transplantation
    • 7-11 September 1997, Nantes, France
    • 30. Lawson JH, Diamond LE, Martin MJ et al. Expression of human complement regulatory proteins CD59 and decay accelerating factor (DAF) prolongs graft survival and physiological function in pig-to-baboon kidney transplantation. In: Proceedings of the Fourth International Congress for Xenotransplantation, 7-11 September 1997, Nantes, France. 1997; Abstract 047.
    • (1997) Proceedings of the Fourth International Congress for Xenotransplantation
    • Lawson, J.H.1    Diamond, L.E.2    Martin, M.J.3
  • 31
    • 0345638658 scopus 로고    scopus 로고
    • Transgenic pig heart and kidneys expressing human CD59, CD55, or CD46 are protected from hyperacute rejection upon transplantation into baboons
    • 7-11 September 1997, Nantes, France
    • 31. Diamond LE, Martin MJ, Adams D et al. Transgenic pig heart and kidneys expressing human CD59, CD55, or CD46 are protected from hyperacute rejection upon transplantation into baboons. In: Proceedings of the Fourth International Congress for Xenotransplantation, 7-11 September 1997, Nantes, France. 1997; Abstract 0185.
    • (1997) Proceedings of the Fourth International Congress for Xenotransplantation
    • Diamond, L.E.1    Martin, M.J.2    Adams, D.3
  • 32
    • 0030966789 scopus 로고    scopus 로고
    • Pig-to-primate cardiac xenotransplantation and cyclophosphamide therapy
    • 32. Waterworth PD, Cozzi E, Tolan MJ et al. Pig-to-primate cardiac xenotransplantation and cyclophosphamide therapy. Transplant. Proc. 1997; 29: 899-900.
    • (1997) Transplant. Proc. , vol.29 , pp. 899-900
    • Waterworth, P.D.1    Cozzi, E.2    Tolan, M.J.3
  • 33
    • 0032523166 scopus 로고    scopus 로고
    • The role of antibodies in acute vascular rejection of pig-to-haboon cardiac transplants
    • 33. Lin S, Weidner BC, Byrne GW et al. The role of antibodies in acute vascular rejection of pig-to-haboon cardiac transplants. J. Clin. Invest. 1998; 101: 1745-56.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1745-1756
    • Lin, S.1    Weidner, B.C.2    Byrne, G.W.3
  • 34
    • 0031410288 scopus 로고    scopus 로고
    • Humoral responses to pig-to-baboon cardiac transplantation: Implications for the pathogenesis and treatment of acute vascular rejection and for accommodation
    • 34. McCurry KR, Parker W, Cotterell AH et al. Humoral responses to pig-to-baboon cardiac transplantation: Implications for the pathogenesis and treatment of acute vascular rejection and for accommodation. Hum. Immunol. 1997; 58: 91-105.
    • (1997) Hum. Immunol. , vol.58 , pp. 91-105
    • McCurry, K.R.1    Parker, W.2    Cotterell, A.H.3
  • 35
    • 0028597554 scopus 로고
    • Mechanisms of injury in porcine livers perfused with blood of patients with fulminant hepatic failure
    • 35. Collins BH, Chari RS, Magee JC et al. Mechanisms of injury in porcine livers perfused with blood of patients with fulminant hepatic failure. Transplantation 1994; 58: 1162-71.
    • (1994) Transplantation , vol.58 , pp. 1162-1171
    • Collins, B.H.1    Chari, R.S.2    Magee, J.C.3
  • 36
    • 0032558089 scopus 로고    scopus 로고
    • Anti-Galα 1-3Gal antibody response to porcine bone marrow in unmodified baboons and baboons conditioned for tolerance induction
    • 36. Kozlowski T, Monroy R, Xu Y et al. Anti-Galα 1-3Gal antibody response to porcine bone marrow in unmodified baboons and baboons conditioned for tolerance induction. Transplantation 1998; 66: 176-82.
    • (1998) Transplantation , vol.66 , pp. 176-182
    • Kozlowski, T.1    Monroy, R.2    Xu, Y.3
  • 38
    • 0028838836 scopus 로고
    • Targeted disruption of the beta 3-adrenergic receptor gene
    • 38. Susulic VS, Frederich RC, Lawitts J et al. Targeted disruption of the beta 3-adrenergic receptor gene. J. Biol. Chem. 1995; 270: 29483-92.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29483-29492
    • Susulic, V.S.1    Frederich, R.C.2    Lawitts, J.3
  • 39
    • 0028982258 scopus 로고
    • Oocyte Gal alpha, 1,3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse
    • 39. Thall AD, Maly P, Lowe JB. Oocyte Gal alpha, 1,3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse. J. Biol. Chem. 1995; 270: 21 437-40.
    • (1995) J. Biol. Chem. , vol.270 , pp. 21437-21440
    • Thall, A.D.1    Maly, P.2    Lowe, J.B.3
  • 40
  • 41
    • 0032964105 scopus 로고    scopus 로고
    • Production of goats by somatic cell nuclear transfer
    • 41 Baguisi A, Behboddi E, Melican DT et al. Production of goats by somatic cell nuclear transfer. Nature Biotech. 1999; 17: 456-61.
    • (1999) Nature Biotech. , vol.17 , pp. 456-461
    • Baguisi, A.1    Behboddi, E.2    Melican, D.T.3
  • 42
    • 0029967424 scopus 로고    scopus 로고
    • Sheep cloned by nuclear transfer from a cultured cell line
    • 42. Campbell KHS, McWhir J, Ritchie WA, Wilmut I. Sheep cloned by nuclear transfer from a cultured cell line. Nature 1998; 380: 64-6.
    • (1998) Nature , vol.380 , pp. 64-66
    • Campbell, K.H.S.1    McWhir, J.2    Ritchie, W.A.3    Wilmut, I.4
  • 44
    • 0032557605 scopus 로고    scopus 로고
    • Cloned transgenic calves produced from nonquiescent fetal fibroblasts
    • 44. Cibelli JB, Stice SL, Golueke PJ et at. Cloned transgenic calves produced from nonquiescent fetal fibroblasts. Science 1998; 280: 1256-8.
    • (1998) Science , vol.280 , pp. 1256-1258
    • Cibelli, J.B.1    Stice, S.L.2    Golueke, P.J.3
  • 45
    • 0032560827 scopus 로고    scopus 로고
    • Full-term development of mice from enucleated oocytes injected with cumulus cells nuclei
    • 45. Wakayama T, Perry ACF, Zuccotti M, Johnson KR, Yanagimachi R. Full-term development of mice from enucleated oocytes injected with cumulus cells nuclei. Nature 1998; 394: 369-74.
    • (1998) Nature , vol.394 , pp. 369-374
    • Wakayama, T.1    Perry, A.C.F.2    Zuccotti, M.3    Johnson, K.R.4    Yanagimachi, R.5
  • 46
    • 0031460988 scopus 로고    scopus 로고
    • Combined transgenic expression of α-galactosidase and α 1,2-fucosyltransferase leads to optimal reduction in the major xenoepitope Galα(1,3)Gal
    • 46. Osman N, Mckenzie IFC, Ostenried K, Ioannou YA, Desnick RJ, Sandrin MS. Combined transgenic expression of α-galactosidase and α 1,2-fucosyltransferase leads to optimal reduction in the major xenoepitope Galα(1,3)Gal. Proc. Natl Acad. Sci. USA 1997; 94: 14677-82.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 14677-14682
    • Osman, N.1    McKenzie, I.F.C.2    Ostenried, K.3    Ioannou, Y.A.4    Desnick, R.J.5    Sandrin, M.S.6
  • 47
    • 0028811673 scopus 로고
    • Enzymatic remodelling of the carbohydrate surface of a xenogenic cell substantially reduces human antibody binding and complement-mediated cytolysis
    • 47. Sandrin MS, Fodor WL, Mouhtouris E et al. Enzymatic remodelling of the carbohydrate surface of a xenogenic cell substantially reduces human antibody binding and complement-mediated cytolysis. Nature Med. 1995;1: 1261-7.
    • (1995) Nature Med. , vol.1 , pp. 1261-1267
    • Sandrin, M.S.1    Fodor, W.L.2    Mouhtouris, E.3
  • 48
    • 0029959441 scopus 로고    scopus 로고
    • Reduction in the level of Gal(α1,3)Gal in transgenic mice and pigs by the expression of an α(1,2)fucosyltransferase
    • 48. Sharma A, Okabe J, Birch P et al. Reduction in the level of Gal(α1,3)Gal in transgenic mice and pigs by the expression of an α(1,2)fucosyltransferase. Proc. Natl Acad. Sci. USA 1996; 93: 7190-5.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 7190-7195
    • Sharma, A.1    Okabe, J.2    Birch, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.