Evaluation of a Human Skin Equivalent for the Treatment of Diabetic Foot Ulcers in a Prospective, Randomized, Clinical Trial

Wounds

Volumn 11, Issue 4, 1999, Pages 79-86

  Pham, Hau T ^a   Rosenblum, B I ^a   Lyons, T E ^a   Giurini, J M ^a   Chrzan, J S ^a   Habershaw, G M ^a   Veves, Aristidis ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Deaconess Joslin Foot Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0033423387     PISSN: 10447946     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Reiber GE, Boyko EJ, Smith DG. Lower extremity foot ulcers and amputations in diabetes. In: National Diabetes Data Group (ed). Diabetes in America, Second Edition. Washington, DC: National Institutes of Health, 1995:409-28.
2. American Diabetes Association. Diabetes: Vital statistics. 1993.
3. Pecoraro RE, Reiber G, Burgess EM. Pathways to diabetic limb amputation; basis for prevention. Diabetes Care 1990;13:513-21.
4. Veves A, Akbari CM, Primavera J, et al. Endothelial dysfunction and the expression of endothelial nitric oxide synthetase in diabetic neuropathy, vascular disease and foot ulceration. Diabetes 1998;47:457-63.
5. American Diabetes Association, Clinical Practice Recommendations. Foot care in patients with diabetes mellitus. Diabetes Care 1996;19(Suppl 1):S23-S24.
6. Myerson M, Papa J, Eaton K, Wilson K. The total contact cast for the management of plantar ulceration of the foot. J Bone Joint Surg 1992;74A:261-4.
7. Camilo LA, Sapico FL, Guiunas VJ, Adkins RH. Randomized controlled trial of topical hyperbaric oxygen for the treatment of diabetic foot ulcers. Diabetes Care 1988;11:111-5.
8. Steed DL, and the Diabetic Ulcer Study. Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity diabetic ulcers. J Vasc Surg 1995;21:71-81.
9. Donaghue VM, Chrzan JS, Rosenblum BI, et al. A clinical evaluation of a collagen-alginate topical wound dressing (FIBRACOL* Dressing) in the management of diabetic foot ulcers. Adv Wound Care 1998;11:114-7.
10. Beli E, Ehrlich HP, Buttle DJ, Nakatsuji T. Living tissue formed in vitro and accepted as skin-equivalent tissue of full thickness. Science 1981;211:1052-1054.
11. Eaglstein WH, Iriondo M, Laszio K. A composite skin substitute (Graftskin) for surgical wounds: A clinical experience. Dermatol Surg 1995;21:839-43.
12. Falanga V, Margolis D, Alvarez O, et al. Rapid healing of venous ulcers and lack of clinical rejection with an allogeneic cultured human skin equivalent. Arch Dermatol 1998;134:293-300.
13. Theobald VA, Lauer JD, Kaplan FA, Baker KB, Rosenberg M. 'Neutral allografts': Lack of allogeneic stimulation by cultured human cells expressing MHC class I and class 11 antigens. Transplantation 1993;55:128-33.
14. Sabolinski ML, Alvarez O, Aulettat M, et al. Cultured skin as a 'smart material' for healing wounds: Experience in venous ulcers. Biomaterials 1996;17:311-20.
15. Steed DL, Donohoe D, Webster MW, Lindsley L. Effect of extensive debridement and treatment on the healing of diabetic foot ulcers. Diabetic Ulcer Study. JAm Coll Surg 1996;183:61-4.
16. Pollak RA, Edington H, Jensen JL, et al. A human dermal replacement for the treatment of diabetic foot ulcers. WOUNDS 1997;9:175-83.
17. Richard JL, Parer-Richard C, Daures JP, et al. Effect of topical basic fibroblast growth factor on the healing of chronic diabetic neurotrophic ulcers of the foot. Diabetes Care 1995;18:64-9.
18. Steed DL. The role of growth factors in wound healing. Surg Clin N Am 1997;77:575-86.
19. Gough A, Clapperton M, Rolando N, et al. Randomized placebo-controlled trial of granulocyte-colony stimulating factor in diabetic foot infection. Lancet 1997;350:855-9.