Cultured skin as a 'smart material' for healing wounds: Experience in venous ulcers

Biomaterials

Volumn 17, Issue 3, 1996, Pages 311-320

  Sabolinski, M L ^a   Alvarez, O ^b   Auletta, M ^b   Mulder, G ^a,c   Parenteau, N L ^a  

^a ORGANOGENESIS INC   (United States)

^b University Wound Healing Clinic   (United States)

^c Wound Healing Institute   (United States)

Author keywords

Graft; Skin; Venous ulcer; Wound healing

Indexed keywords

BIOMATERIALS; CYTOLOGY; GRAFTS; GROWTH KINETICS; TISSUE CULTURE;

CHRONIC WOULD THERAPY; CYTOKINES; DERMAL REGENERATION; EXTRACELLULAR MATRIX; SKIN TISSUE ENGINEERING; VENOUS ULCERS; WOUND HEALING;

SKIN;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SKIN CULTURE; SKIN GRAFT; ULCER; WOUND CLOSURE; WOUND HEALING;

EID: 0030087840     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/0142-9612(96)85569-4     Document Type: Article

References (31)

1. Nathan C, Sporn M. Cytokines in context. J Cell Biol 1991; 113: 981-986.
2. Ruoslahti E, Yamaguchi Y. Proteoglycans as modulators of growth factor activities. Cell 1991; 64: 867-869.
3. Ansel J, Perry P, Brown J et al. Cytokine modulation of keratinocyte cytokines. J Invest Dermatol 1990; 94: 101S-107S.
4. Rothe M, Falanga V. Growth factors. Arch Dermatol 1989; 125: 1390-1398.
5. Clark RAF. Mechanisms of cutaneous wound repair. In: Westerhof W. ed. Leg Ulcers: Diagnosis and Treatment. New York: Elsevier Science Publishers. 1993: 29-50.
6. Mast BA, Nelson JM, Krummol TM. Tissue repair in the mammalian fetus. In: Cohen IK, Diegelmann RF, Lindblad WJ, eds. Wound Healing: Biochemical and Clinical Aspects. Philadelphia. W.B. Saunders Co., 1992: 326-341.
7. Skerrett PJ. 'Matrix algebra' heal's life's wounds. Science 1991; 252: 1064-1066.
8. Yannas IV, Burke JF, Orgill DP, Skrabut EM. Wound tissue can utilize a polymeric template to synthesize a functional extension of skin. Science 1982; 215: 174-176.
9. Doillon CJ, Berg RA, Silver FH. Behaviour of fibroblasts and epidermal cells cultivated on analogues of extracellular matrix. Biomaterials 1988; 9: 991-996.
10. Hansbrough JF, Boyce ST, Cooper ML, Foreman TJ. Burn wound closure with cultured autologous keratinocytes and fibroblasts attached to a collagen-glycosaminoglycan substrate. JAMA 1989; 262: 2125-2130.
11. Bell E, Rosenberg M, Kemp P, et al. Recipes for reconstituting skin. J Biomech Engng 1981; 113: 113-119.
12. Heimbach D, Luterman A, Burke JF et al. Artificial dermis for major burns: a multi-center randomized clinical trial. Ann Surg 1988; 208: 313-320.
13. Gallico GG III, O'Connor NE, Compton CC et al. Permanent coverage of large burn wounds with autologous cultured human epithelium. N Engl J Med 1984; 311: 448-451.
14. Green H, Kehinde O, Thomas J. Growth of cultured human epidermal cells into multiple epithelia suitable for grafting. Proc Nat Acad Sci USA 1979; 76: 5665-5668.
15. Bell E, Ehrlich P, Buttle DJ, Nakatsuji T. Living tissue formed in vitro and accepted as skin-equivalent of full-thickness. Science 1981; 221: 1052-1054.
16. Johnson EW, Meunier SF, Roy CJ, Parenteau NL. Serial cultivation of normal human keratinocytes: a defined system for studying the regulation of growth and differentiation. In Vitro Cell Develop Biol 1992; 28A: 429-435.
17. Parenteau NL. Skin equivalents. In: Leigh I, Watt F, Lane B, eds. Keratinocyte Methods. London: Cambridge University Press, 1994.
18. Parenteau NL, Bilbo P, Nolte CJM, Mason VS, Rosenberg M. The organotypic culture of human skin keratinocvtes and fibroblasts to achieve form and function. Cytotechnology 1992; 9: 163-171.
19. Bilbo PR, Nolte CJM, Oleson MA, Mason VA, Parenteau NL. Skin in complex culture: the transition from "culture§ phenotype to organotypic phenotype. J Toxicol Cut Ocular Toxicol 1993; 12: 183-196.
20. Wilkins LM, Watson SR, Prosky SJ, Meunier SF, Parenteau NL. Development of a bilayered living skin construct for clinical applications. Biotechnol Bioengng 1994; 43: 747-756.
21. Leigh IM, Purkis PE, Navsaria HA, Phillips T. Treatment of chronic venous ulcers with sheets of cultured allogeneic keratinocytes. Br J Dermatol 1987; 117: 591-597.
22. DeLuca M, Albaese E, Cancedda R et al. Treatment of leg ulcers with cryopreserved allogeneic cultured epithelium. Arch Dermatol 1992; 128: 633-638.
23. McKay IA, Leigh IM. Epidermal cytokines and their roles in cutaneous wound healing. Br J Dermatol 1991; 124: 513-518.
24. Nanninga PB, Mekkes JR, De Vries HJC, Westerhof W, Teepe RGC, Barrandon Y. Grafting techniques. In: Westerof W, ed. Leg Ulcers: Diagnosis and Treatment. NY: Elsevier, 1993: 340-344.
25. Margolis D, Cohen IK. Management of chronic venous leg ulcers: a literature-guided approach. Clin Dermatol 1994; 12: 19-26.
26. Ehrlich HP, Rajaratnam JBM. Cell locomotion forces versus cell contraction forces for collagen lattice contraction: an in vitro model of wound contraction. Tissue Cell 1990; 22: 407-417.
27. Nolte CJM, Oleson MA Bilbo PR, Parenteau NL. Development of a stratum corneum and barrier function in an organotypic skin culture. Arch Dermatol Res 1993; 285: 466-474.
28. Nolte CJM, Oleson MA, Hansbrough JF, Morgan J, Greenleaf G, Wilkins L. Ultrastructural features of composite skin cultures grafted onto athymic mice. J Anat 1994; 185: 325-333.
29. Martin P, Hopkinson-Woolley J, McCluskey J. Growth factors and cutaneous wound repair. Prog Growth Hormone Res 1992; 4: 25-44.
30. Hansbrough JF, Morgan J, Greenleaf G, Parikh M, Nolte C, Wilkins L. Evaluation of Graftskin composite grafts on full-thickness wounds on athymic mice. J Burn Care Rehab 1994; 15: 346-353.
31. Lazarus GS, Cooper DM, Knighton DR et al. Definitions and guidelines for assessment of wounds and evaluation of healing. Wound Repair Regen 1994; 130: 489-493.