Intratracheally applied rSP-C surfactant exhibits no anaphylactic shock reactions in a guinea pig model of acute lung hypersensitivity

Experimental and Toxicologic Pathology

Volumn 51, Issue 6, 1999, Pages 495-505

  Germann, Paul Georg ^a,b   Kemkowski, Jörg ^a   Hauschke, Dieter ^a   Steinhilber, Wolfram ^a   Häfner, Dietrich ^a  

^a ALTANA PHARMA AG   (Germany)

^b Section Head of Pathology Preclinical Safety   (Switzerland)

Author keywords

Anaphylactic lung shock; Hypersensitivity, lung; Immunohistology of SP C; Lung hypersensitivity; Ovalbumin; RSP C surfactant; Shock, anaphylactic; Surfactant, rSP C

Indexed keywords

OVALBUMIN; PHOSPHOLIPID; POLYCLONAL ANTIBODY; RECOMBINANT PROTEIN; SURFACTANT PROTEIN C;

ANAPHYLACTIC SHOCK; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; GUINEA PIG; HISTOPATHOLOGY; HYPERSENSITIVITY; IMMUNOHISTOCHEMISTRY; LUNG DISEASE; LUNG WEIGHT; MORTALITY; NONHUMAN;

ANIMALIA; BRONCHUS; CAVIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0033402220     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0940-2993(99)80125-0     Document Type: Article

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