In vitro and in vivo protein oxidation induced by Alzheimer's disease amyloid β-peptide (1-42)

Annals of the New York Academy of Sciences

Volumn 893, Issue , 1999, Pages 265-268

  Butterfield, D Allan ^a   Yatin, Servet M ^a   Link, Christopher D ^b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; ANTIOXIDANT; CYSTEINE; FREE RADICAL; METHIONINE; PROTEIN;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; CONFERENCE PAPER; HIPPOCAMPUS; NERVE CELL CULTURE; NEUROTOXICITY; OXIDATION; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN EXPRESSION;

EID: 0033401851     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb07833.x     Document Type: Conference Paper

References (12)

1. 1. Selkoe, D. 1994. Alzheimer's disease: a central role of amyloid. J. Neuropathol. Exp. Neurol 53: 438-447.
2. 2. Butterfield, D.A. 1997. β-amyloid-associated free radical oxidative stress and neurotoxicity: implications for Alzheimer's disease. Chem. Res. Toxicol. 10: 495-506.
3. 3. Markesbery, W.R. 1997. Oxidative stress hypothesis in Alzheimer disease. Free Radical Biol. Med. 23: 134-147.
4. 4. Butterfield, D.A., K. Hensley, M. Harris, M. Mattson & J. M. Carney. 1994. β-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease. Biochem. Biophys. Res. Commun. 200: 710-715.
5. 5. Koppal, T., R. Subramaniam, J. Drake, M.R. Prasad & D.A. Butterfield. 1998. Vitamin E protects against Alzheimer's amyloid peptide (25-35)-induced changes in neocortical synaptosomal membrane lipid structure and composition. Brain Res. 786: 270-273.
6. 6. Subramaniam, R., T. Koppal, M. Green, S. Yatin, B. Jordan, J. Drake & D.A. Butterfield. 1998. The free radical antioxidant vitamin E protects cortical synaptosomal membranes from amyloid beta-peptide (25-35) toxicity but not from hydroxynonenal toxicity: relevance to the free radical hypothesis of Alzheimer's disease. Neurochem. Res. 23: 1403-1410.
7. 7. Yatin, S.M., M. Aksenov & D.A. Butterfield. 1999. The antioxidant vitamin E modulates amyloid β-peptide-induced creatine kinase activity inhibition and increased protein oxidation: implications for the free radical hypothesis of Alzheimer's disease. Neurochem. Res. 24: 427-435.
8. 8. Harris, M., K. Hensley, D.A. Butterfield, R.A. Leedle & J.M. Carney. 1995. Direct evidence of oxidative injury produced by the Alzheimer's amyloid beta-peptide (1-40) in cultured hippocampal neurons. Exp. Neurol. 131: 193-202.
9. 9. Butterfield, D.A. & E.R. Stadtman. 1997. Protein oxidation processes in aging brain. Adv. Cell Aging Gerontol. 2: 161-191.
10. 10. Hensley, K., N. Hall, R. Subramaniam, P. Cole, M. Harris, M. Aksenov, M. Aksenova, S.P. Gabbita, J.F. Wu, J.M. Carney, M. Lovell, W.R. Markesbery & D.A. Butterfield. 1995. Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation, J. Neurochem. 65: 2146-2156
11. 11. Fay, D., A. Fluet, C. Johnson & C. Link. 1998. In vivo aggregation of beta-amyloid peptide variants. J. Neurochem. 71: 1616-1625.
12. 12. Varadarajan, S., S. Yatin, J. Kanski, F. Jahanshaki & D.A. Butterfield. 1999. Methionine residue 35 is important in amyloid b-peptide-associated free radical oxidative stress. Submitted for publication.