High level expression of CD43 inhibits T cell receptor/CD3-mediated apoptosis

Journal of Experimental Medicine

Volumn 190, Issue 12, 1999, Pages 1903-1908

  He, You Wen ^a   Bevan, Michael J ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Activation induced apoptosis; CD43; Fas; Memory CD4+ T cells

Indexed keywords

CD3 ANTIGEN; LEUKOSIALIN; T LYMPHOCYTE RECEPTOR;

ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYBRIDOMA; MEMORY CELL; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; TUMOR CELL;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD43; ANTIGENS, CD95; APOPTOSIS; CD4-POSITIVE T-LYMPHOCYTES; HYBRIDOMAS; MICE; RECEPTORS, ANTIGEN, T-CELL; SIALOGLYCOPROTEINS; SIGNAL TRANSDUCTION;

EID: 0033400455     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.190.12.1903     Document Type: Article

References (28)

1. Dutton, R.W., L.M. Bradley, and S.L. Swain. 1998. T cell memory. Annu. Rev. Immunol. 16:201-223.
2. + T cell responses to Fas engagement. Proc. Natl. Acad. Sci. USA. 96: 8104-8109.
3. Inaba, M., K. Kurasawa, M. Mamura, K. Kumano, Y. Saito, and I. Iwamoto. 1999. Primed T cells are more resistant to Fas-mediated activation-induced cell death than naive T cells. J. Immunol. 163:1315-1320.
4. + T cells. J. Immunol. 163: 1817-1826.
5. Lenardo, M.J. 1997. The molecular regulation of lymphocyte apoptosis. Semin. Immunol. 9:1-5.
6. Remold-O'Donnell, E., and F.S. Rosen. 1990. Sialophorin (CD43) and the Wiskott-Aldrich syndrome. Immunodefic. Rev. 2:151-174.
7. Park, J.K., Y.J. Rosenstein, E. Remold-O'Donnell, B.E. Bierer, F.S. Rosen, and S.J. Burakoff. 1991. Enhancement of T-cell activation by the CD43 molecule whose expression is detective in Wiskott-Aldrich syndrome. Nature. 350:706-709.
8. Sperling, A.I., J.M. Green, R.L. Mosley, P.L. Smith, R.J. DiPaolo, J.R. Klein, J.A. Bluestone, and C.B. Thompson. 1995. CD43 is a murine T cell costimulatory receptor that functions independently of CD28. J. Exp. Med. 182:139-146.
9. Manjunath, N., M. Correa, M. Ardman, and B. Ardman. 1995. Negative regulation of T-cell adhesion and activation by CD43. Nature. 377:535-538.
10. McEvoy, L.M., H. Sun, J.G. Frelinger, and E.G. Butcher. 1997. Anti-CD43 inhibition of T cell homing. J. Exp. Med. 185:1493-1498.
11. Stockton, B.M., G. Cheng, N. Manjunath, B. Ardman, and U.H. von Andrian. 1998. Negative regulation of T cell homing by CD43. Immunity. 8:373-381.
12. Bazil, V., J. Brandt, A. Tsukamoto, and R. Hoffman. 1995. Apoptosis of human hematopoietic progenitor cells induced by crosslinking of surface CD43, the major sialoglycoprotein of leukocytes. Blood. 86:502-511.
13. Brown, T.J., W.W. Shuford, W.C. Wang, S.C., Nadler, T.S. Bailey, H. Marquardt, and R.S. Mittler. 1996. Characterization of a CD43/leukosialin-niediated pathway for inducing apoptosis in human T-lymphoblastoid cells. J. Biol. Chem. 271:27686-27695.
14. 1 arrest and extends survival in culture upon serum depletion. Eur. J. Immunol. 26:2573-2581.
15. Hitoshi, Y., J. Lorens, S.-I. Kitada, J. Fisher, M. LaBarge, H.Z. Ring, U. Francke, J.C. Reed, S. Kinoshita, and G.P. Nolan. 1998. Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells. Immunity. 8:461-171.
16. He, Y.-W., M.L. Deftos, E.W. Ojala, and M.J. Bevan. 1998. RORγt, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells. Immunity. 9:797-806.
17. Deftos, M.L., Y.-W. He, E.W. Ojala, and M.J. Bevan. 1998. Correlating notch signaling with thymocyte maturation. Immunity. 9:777-786.
18. Zheng, L., G. Fisher, R.E. Miller, J. Peschon, D.H. Lynch, and M.J. Lenardo. 1995. Induction of apoptosis in mature T cells by tumour necrosis factor. Nature. 377:348-351.
19. Shaw, A.S., and M.L. Dustin. 1997. Making the T cell receptor go the distance: a topological view of T cell activation. Immunity. 6:361-369.
20. Thurman, E.C., J. Walker, S. Jayaraman, N. Manjunath, B. Ardman, and J.M. Green. 1998. Regulation of in vitro and in vivo T cell activation by CD43. Int. Immunol. 10:691-701.
21. Walker, J., and J.M. Green. 1999. Structural requirements for CD43 function. J. Immunol. 162:4109-4114.
22. Sperling, A.I., J.R. Sedy, N. Manjunath, A. Kupfer, B. Ardman, and J.K. Burkhardt. 1998. Cutting edge: TCR signaling induces selective exclusion of CD43 from the T cell-antigen-presenting cell contact site. J. Immunol. 161:6459-6462.
23. Alvarado, M., C. Klassen, J. Cerny, V. Horejsi, and R.E. Schmidt. 1995. MEM-59 monoclonal antibody detects a CD43 epitope involved in lymphocyte activation. Eur. J. Immunol. 25:1051-1055.
24. Misawa, Y., and M. Shibuya. 1992. Amplification and rearrangement of melF/mouse CD43 (leukosialin) gene encoding a highly glycosylated membrane protein gp120 in Friend erythroleukemia cells. Oncogene. 7:919-926.
25. Baeckstrom, D., K. Zhang, N. Asker, U. Ruetschi, M. Ek, and G.C. Hansson. 1995. Expression of the leukocyte-associated sialoglycoprotein CD43 by a colon carcinoma cell line. J. Biol. Clicm. 270:13688-13692.
26. Santamaria, M., A. Lopez-Beltran, M. Toro, J. Pena, I.J. Molina. 1996. Specific monoclonal antibodies against leukocyte-restricted cell surface molecule CD43 react with nonhematopoietic tumor cells. Cancer Res. 56:3526-3529.
27. Sikut, R., O. Nilsson, D. Baeckstrom, and G.C. Hansson. 1997. Colon adenoma and cancer cells aberrantly express the leukocyte-associated sialoglycoprotein CD43. Biochem. Biophys. Res. Commun. 238:612-616.
28. McFarland, T.A., B. Ardman, N. Manjunath, J.A. Fabry, and J. Lieberman. 1995. CD43 diminishes susceptibility to T lymphocyte-mediated cytolysis. J. Immunol. 154:1097-1104.