Effect of imipramine on enkephalin-degrading peptidases

European Neuropsychopharmacology

Volumn 9, Issue 6, 1999, Pages 493-499

  De Gandarias, Juan Manuel ^a   Irazusta, Jon ^a   Varona, Adolfo ^a   Gil, Javier ^a   Fernández, David ^a   Casis, Luis ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Aminopeptidase; Enkephalins; Imipramine; Neutral endopeptidase 24.11; Opioids

Indexed keywords

2 NAPHTHYLAMINE; AMINOPEPTIDASE; ENDORPHIN; ENKEPHALIN; IMIPRAMINE; MEMBRANE METALLOENDOPEPTIDASE; PUROMYCIN;

ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; ENZYME ACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BRAIN; ENKEPHALINS; IMIPRAMINE; MALE; PEPTIDE HYDROLASES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0033399853     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-977X(99)00035-8     Document Type: Article

References (27)

1. Alba F., Iribar C., Ramirez M., Arenas C. A fluorimetric method for the determination of brain aminopeptidases. Arch. Neurobiol. 52:1989;169-173.
2. Baamonde A., Dauge V., Ruiz-Gayo M., Fulga I.G., Turcaud S., Fournie-Zaluski M.C. Antidepressant-type effects of endogenous enkephalins protected by systemic RB101 are mediated by opioid delta and dopamine D1 receptor stimulation. Eur. J. Pharmacol. 216:1992;157-166.
3. Besret L., Debruyene D., Rioux P., Bonvalot T., Moulin M., Zafirian E., Baron J.C. A comprehensive investigation of plasma and brain regional pharmacokinetics of imipramine and its metabolites during and after chronic administration in the rat. J. Pharm. Sci. 85:1996;291-295.
4. Bodkin J.A., Zornberg G.L., Lukas S.E., Cole J.O. Buprenorphine treatment of refractory depression. J. Clin. Psychopharmacol. 15:1995;49-57.
5. Bradford M.M. A rapid and sensitive method for the quantification of microgram of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
6. Chaillet P., Marçais-Collado H., Costentin J., Ching-Cheng Y., de la Baume S., Schwartz J.C. Inhibition of enkephalin metabolism by, and antinocioceptive activity of, bestatin, an aminopeptidase inhibitor. Eur. J. Pharmacol. 86:1983;329-336.
7. De Felipe M.C., Ceballos M.L., Gil C., Fuentes J.A. Chronic antidepressant treatment increases enkephalin levels in n. accumbens and striatum of the rat. Eur. J. Pharmacol. 112:1985;119-122.
8. De Felipe M.C., Jimenez Y., Castro A., Fuentes J.A. Antidepressant action of imipramine and iprindole in mice is enhanced by inhibitors of enkephalin-degrading peptidases. Eur. J. Pharmacol. 159:1989;175-180.
9. De Gandarias J.M., Ramirez M., Zulaica J., Iribar C., Casis L. Postnatal development of aminopeptidase (arylamidase) activity in the rat brain. J. Biochem. 105:1989;44-46.
10. De Gandarias J.M., Irazusta J., Fernández D., Gallego M., Silió M., Casis L. Membrane-bound tyrosine aminopeptidase activities in the rat brain throughout the estrous cycle. Life Sci. 59:1996;1097-1101.
11. De Gandarias J.M., Casis O., Varona A., Gallego M., Irazusta J., Casis L. Interaction mechanism of imipramine and desipramine with enkephalin-degrading aminopeptidases in vitro. Life Sci. 61:1997;PL321-PL326.
12. Dyer S.H., Slaughter C.A., Orth K., Moomaw C.R., Hersh L.B. Comparison of the soluble and membrane-bound forms of the puromycin sensitive enkephalin-degrading aminopeptidases from rat. J. Neurochem. 54:1990;547-554.
13. Florentin D., Sassi A., Roques B.P. A highly sensitive fluorometric assay for "enkephalinase", a neutral metalloendopeptidase that releases tyrosine-glycine-glycine from enkephalins. Anal. Biochem. 141:1984;62-69.
14. Fisar Z., Krulik R., Fuksova K., Sikora J. Imipramine distribution among red blood cells, plasma and brain tissue. Gen. Physiol. Biophys. 15:1996;51-64.
15. Giardina W.J., Ebert D.M. Positive effects of captopril in the behaviour despair swim test. Biol. Psychiatry. 25:1989;697-702.
16. 5)enkephalin in brain slices using peptidase inhibitors and anti-aminopeptidase M antibodies. Mol. Pharmacol. 29:1986;281-287.
17. -14 mole. Biochem. Biophys. Res. Commun. 9:1962;430-435.
18. Hersh L.B. Degradation of enkephalins: the search for an enkephalinase. Mol. Cell. Biochem. 47:1982;35-42.
19. Herman Z.S., Obuchoiwicz E., Kowalski J., Plech A. Leu-enkephalin content in rat brain during prolonged treatment with imipramine or amitriptilyne. Neuropeptides. 7:1986;113-124.
20. Kalra S.P. Neural circuitry involved in the control of LHRH secretion: a model for preovulatory LH release. Ganong W.F., Martini L. Frontiers in Neuroendocrinology. IX:1986;31-71 Raven Press, New York.
21. Kurumaji A., Mitsushio H., Takashima M. Chronic dietary treatment with antidepressant decreases brain Met-enkephalin-like immunoreactivity in the rat. Psycopharmacology. 94:1988;188-192.
22. Roques B.P., Noble F., Daugie V., Fournie-Zaluski M.C., Beaumont A. Neutral endopeptidase 24.11: Structure, inhibition and experimental and clinical pharmacology. Pharmacol. Rev. 45:1993;87-146.
23. Scarone S., Gambini O., Calabrese G., Sacerdote P., Bruni M., Carucci M., Panerai A.E. Assymetrical distribution of β-endorphin in cerebral hemispheres of suicides: preliminary data. Psychiatry Res. 32:1990;159-166.
24. Takahashi R.N., Paz M.M. Influence of naloxone on analgesic effects of antidepressants in mice. Braz. J. Med. Biol. Res. 20:1987;607-610.
25. Tejedor-Real P., Mico J.A., Maldonado R., Roques B.P., Gibert-Rahola J. Effect of mixed (RB38A) and selective (RB38B) inhibitors of enkephalin degrading enzymes on a model of depression in the rat. Biol. Psychiatry. 34:1993;100-107.
26. Tejedor-Real P., Mico J.A., Maldonado R., Roques B.P., Gibert-Rahola J. Implication of endogenous opioid system in the learned helplessness model of depression. Pharmacol. Biochem. Behav. 52:1995;145-152.
27. Wagner G.W., Tavianini M.A., Herrmann K.M., Dixon J.E. Purification and characterization of an enkephalin aminopeptidase from rat brain. Biochemistry. 20:1981;3884-3890.