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Volumn 19, Issue 12, 1999, Pages 2826-2834

Dissecting the genetic architecture of lipids, lipoproteins, and apolipoproteins: Lessons from twin studies

Author keywords

Age; Genetics; Lipids; Pleiotropy; Twin studies

Indexed keywords

APOLIPOPROTEIN; LIPID; LIPOPROTEIN;

EID: 0033398918     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.19.12.2826     Document Type: Short Survey
Times cited : (76)

References (101)
  • 1
    • 0030906941 scopus 로고    scopus 로고
    • Human genetics: Twins: En route to QTLs for cognition
    • Gottesman II. Human genetics: twins: en route to QTLs for cognition. Science. 1997;276:1522-1523.
    • (1997) Science , vol.276 , pp. 1522-1523
    • Gottesman, I.I.1
  • 2
    • 0030662348 scopus 로고    scopus 로고
    • A twin pronged attack on complex traits
    • Martin NG, Boomsma DI, Machin G. A twin pronged attack on complex traits. Nat Genet. 1997;17:387-392.
    • (1997) Nat Genet. , vol.17 , pp. 387-392
    • Martin, N.G.1    Boomsma, D.I.2    Machin, G.3
  • 3
    • 0001991099 scopus 로고
    • Lipids, apolipoproteins and lipoproteins
    • Goldbourt U, de Faire U, Berg K, eds. Dordrecht, Netherlands: Kluwer
    • Rader DJ, Brewer HB. Lipids, apolipoproteins and lipoproteins. In: Goldbourt U, de Faire U, Berg K, eds. Genetic Factors in Coronary Mean Disease. Dordrecht, Netherlands: Kluwer; 1994:83-103.
    • (1994) Genetic Factors in Coronary Mean Disease , pp. 83-103
    • Rader, D.J.1    Brewer, H.B.2
  • 4
    • 47649091099 scopus 로고
    • A new serum type system in man: The Lp system
    • Berg K. A new serum type system in man: the Lp system. Acta Pathol Microbiol Immunol Scand. 1963;59:369-382.
    • (1963) Acta Pathol Microbiol Immunol Scand. , vol.59 , pp. 369-382
    • Berg, K.1
  • 5
    • 0024362630 scopus 로고
    • The mysteries of lipoprotein(a)
    • Utermann G. The mysteries of lipoprotein(a). Science. 1989;246: 904-910.
    • (1989) Science , vol.246 , pp. 904-910
    • Utermann, G.1
  • 6
    • 84910815452 scopus 로고
    • Lp(a) lipoprotein as a risk factor for myocardial infarction
    • Rhoads GG, Dahlen G, Berg K, Morton NE, Dannenberg AL. Lp(a) lipoprotein as a risk factor for myocardial infarction. JAMA. 1986;256: 2540-2544.
    • (1986) JAMA , vol.256 , pp. 2540-2544
    • Rhoads, G.G.1    Dahlen, G.2    Berg, K.3    Morton, N.E.4    Dannenberg, A.L.5
  • 7
    • 0023940579 scopus 로고
    • Apolipoproteins(a), AI, and B, and parental history in men with early onset ischaemic heart-disease
    • Durrington PN, Ishola M, Hunt L, Arrol S, Bhatnagar D. Apolipoproteins(a), AI, and B, and parental history in men with early onset ischaemic heart-disease. Lancet. 1988;1:1070-1073.
    • (1988) Lancet , vol.1 , pp. 1070-1073
    • Durrington, P.N.1    Ishola, M.2    Hunt, L.3    Arrol, S.4    Bhatnagar, D.5
  • 9
    • 0029838433 scopus 로고    scopus 로고
    • Plasma triglyceride level is an independent risk factor for cardiovascular disease: A meta-analysis of population based prospective studies
    • Hokanson JE, Austin MA. Plasma triglyceride level is an independent risk factor for cardiovascular disease: a meta-analysis of population based prospective studies. J Cardiovasc Risk. 1996;3:213-219.
    • (1996) J Cardiovasc Risk , vol.3 , pp. 213-219
    • Hokanson, J.E.1    Austin, M.A.2
  • 11
    • 0026602203 scopus 로고
    • Early expression of the apolipoprotein(a) gene: Relationships between infants' and their parents' serum apolipoprotein(a) levels
    • Wang XL, Wilcken DEL, Dudman NPB. Early expression of the apolipoprotein(a) gene: relationships between infants' and their parents' serum apolipoprotein(a) levels. Pediatrics. 1992;89:401-406.
    • (1992) Pediatrics , vol.89 , pp. 401-406
    • Wang, X.L.1    Wilcken, D.E.L.2    Dudman, N.P.B.3
  • 13
    • 0017157137 scopus 로고
    • Serum cholesterol and triglyceride levels in 3,446 children from a biracial community: The Bogalusa Heart Study
    • Frerichs RR, Srinivasan SR, Webber LS, Berenson GS. Serum cholesterol and triglyceride levels in 3,446 children from a biracial community: the Bogalusa Heart Study. Circulation. 1976;54:302-308.
    • (1976) Circulation , vol.54 , pp. 302-308
    • Frerichs, R.R.1    Srinivasan, S.R.2    Webber, L.S.3    Berenson, G.S.4
  • 15
    • 0028920543 scopus 로고
    • Longitudinal development of lipoprotein levels in males and females aged 12-28 years: The Amsterdam Growth and Health Study
    • Twisk JWR, Kemper HCG, Mellenbergh GJ. Longitudinal development of lipoprotein levels in males and females aged 12-28 years: the Amsterdam Growth and Health Study. Int J Epidemiol. 1995;24:69-77.
    • (1995) Int J Epidemiol. , vol.24 , pp. 69-77
    • Twisk, J.W.R.1    Kemper, H.C.G.2    Mellenbergh, G.J.3
  • 16
    • 0027450017 scopus 로고
    • Lipoprotein(a): Relation to other risk factors and genetic heritability: Results from a Dutch parent-twin study
    • Boomsma DI, Kaptein A, Kempen HJM, Gevers Leuven JA, Princen HMG. Lipoprotein(a): relation to other risk factors and genetic heritability: results from a Dutch parent-twin study. Atherosclerosis. 1993;99: 23-33.
    • (1993) Atherosclerosis , vol.99 , pp. 23-33
    • Boomsma, D.I.1    Kaptein, A.2    Kempen, H.J.M.3    Gevers Leuven, J.A.4    Princen, H.M.G.5
  • 17
    • 0029096323 scopus 로고
    • Serum lipid values in adolescents are related to family history, infant feeding, and physical growth
    • Bergstrom E, Hernell O, Persson LA, Vessby B. Serum lipid values in adolescents are related to family history, infant feeding, and physical growth. Atherosclerosis. 1995;117:1-13.
    • (1995) Atherosclerosis , vol.117 , pp. 1-13
    • Bergstrom, E.1    Hernell, O.2    Persson, L.A.3    Vessby, B.4
  • 20
    • 0028245373 scopus 로고
    • Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study
    • Schaefer EJ, Lamon-Fava S, Cohn SD, Schaefer MM, Ordovas JM, Castelli WP, Wilson PWF. Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study. J Lipid Res. 1994;35: 779-792.
    • (1994) J Lipid Res. , vol.35 , pp. 779-792
    • Schaefer, E.J.1    Lamon-Fava, S.2    Cohn, S.D.3    Schaefer, M.M.4    Ordovas, J.M.5    Castelli, W.P.6    Wilson, P.W.F.7
  • 24
    • 0025359910 scopus 로고
    • Total and HDL cholesterol, and their correlates in elderly men in Finland, Italy and the Netherlands
    • Kromhout D, Nissinen A, Menotti A, Bloemberg B, Pekkanen J, Giampaoli S. Total and HDL cholesterol, and their correlates in elderly men in Finland, Italy and The Netherlands. Am J Epidemiol. 1990;131: 855-863.
    • (1990) Am J Epidemiol. , vol.131 , pp. 855-863
    • Kromhout, D.1    Nissinen, A.2    Menotti, A.3    Bloemberg, B.4    Pekkanen, J.5    Giampaoli, S.6
  • 25
    • 0027167905 scopus 로고
    • Total serum cholesterol levels and mortality risk as a function of age
    • Kronmal RA, Cain KC, Ye Z, Omenn GS. Total serum cholesterol levels and mortality risk as a function of age. Arch Intern Med. 1993;153: 1065-1073.
    • (1993) Arch Intern Med. , vol.153 , pp. 1065-1073
    • Kronmal, R.A.1    Cain, K.C.2    Ye, Z.3    Omenn, G.S.4
  • 26
    • 0026644348 scopus 로고
    • Aging and total cholesterol levels: Cohort period and survivorship effects
    • Newschaffer CJ, Bush TL, Hale WE. Aging and total cholesterol levels: cohort period and survivorship effects. Am J Epidemiol. 1992;136: 23-34.
    • (1992) Am J Epidemiol. , vol.136 , pp. 23-34
    • Newschaffer, C.J.1    Bush, T.L.2    Hale, W.E.3
  • 27
    • 0018080777 scopus 로고
    • Relationship of blood pressure, serum cholesterol, smoking habit, relative weight and ecg abnormalities to incidence of major coronary events: Final report of the Pooling Project
    • Pooling Project Research Group. Relationship of blood pressure, serum cholesterol, smoking habit, relative weight and ecg abnormalities to incidence of major coronary events: final report of the Pooling Project. J Chronic Dis. 1978;31:201-306.
    • (1978) J Chronic Dis. , vol.31 , pp. 201-306
  • 28
    • 0025038552 scopus 로고
    • The effects of generation and gender on the joint distributions of lipid and apolipoprotein phenotypes in the population at large
    • Reilly L, Kottke BA, Sing CF. The effects of generation and gender on the joint distributions of lipid and apolipoprotein phenotypes in the population at large. J Clin Invest. 1990;43:921-940.
    • (1990) J Clin Invest. , vol.43 , pp. 921-940
    • Reilly, L.1    Kottke, B.A.2    Sing, C.F.3
  • 29
    • 0029983206 scopus 로고    scopus 로고
    • Genetic analysis of sex and generation differences in plasma lipid lipoprotein and apolipoprotein levels in adolescent twins and their parents
    • Boomsma DI, Kempen HM, Gevers LJ, Havekes L, de Knijff P, Frants RR. Genetic analysis of sex and generation differences in plasma lipid lipoprotein and apolipoprotein levels in adolescent twins and their parents. Genet Epidemiol. 1996;13:49-60.
    • (1996) Genet Epidemiol. , vol.13 , pp. 49-60
    • Boomsma, D.I.1    Kempen, H.M.2    Gevers, L.J.3    Havekes, L.4    De Knijff, P.5    Frants, R.R.6
  • 30
    • 0001118904 scopus 로고
    • Genetic defects in lipoprotein metabolism
    • Goldbourt U, de Faire U, Berg K, eds. Dordrecht, Netherlands: Kluwer
    • Schonfeld G, Krul ES. Genetic defects in lipoprotein metabolism. In: Goldbourt U, de Faire U, Berg K, eds. Genetic Factors in Coronary Heart Disease. Dordrecht, Netherlands: Kluwer; 1994:239-266.
    • (1994) Genetic Factors in Coronary Heart Disease , pp. 239-266
    • Schonfeld, G.1    Krul, E.S.2
  • 31
    • 0018397813 scopus 로고
    • Analysis of family resemblance for lipids and lipoproteins
    • Iselius L. Analysis of family resemblance for lipids and lipoproteins. Clin Genet. 1979;15:300-306.
    • (1979) Clin Genet. , vol.15 , pp. 300-306
    • Iselius, L.1
  • 32
    • 0008600191 scopus 로고
    • Genetic epidemiology of common diseases in humans
    • Weir BS, Eisen EJ, Goodman MM, Namkoong G, eds. Sunderland: Sinauer
    • Iselius L. Genetic epidemiology of common diseases in humans. In: Weir BS, Eisen EJ, Goodman MM, Namkoong G, eds. Proceedings of The Second International Conference on Quantitative Genetics. Sunderland: Sinauer; 1988:341-352.
    • (1988) Proceedings of the Second International Conference on Quantitative Genetics , pp. 341-352
    • Iselius, L.1
  • 36
    • 0342717373 scopus 로고
    • Assessing genetic and cultural heritabilities
    • Goldbourt U, de Faire U, Berg K, eds. Dordrecht, Netherlands: Kluwer
    • Rao DC, Vogler GP. Assessing genetic and cultural heritabilities. In: Goldbourt U, de Faire U, Berg K, eds. Genetic Factors in Coronary Mean Disease. Dordrecht, Netherlands: Kluwer; 1994:71-81.
    • (1994) Genetic Factors in Coronary Mean Disease , pp. 71-81
    • Rao, D.C.1    Vogler, G.P.2
  • 37
    • 0028116098 scopus 로고
    • Genetic and environmental effects on coronary heart disease risk factors in northern Norway: The cardiovascular disease study in Finnmark
    • Brenn T. Genetic and environmental effects on coronary heart disease risk factors in northern Norway: the cardiovascular disease study in Finnmark. Ann Hum Genet. 1994;58:369-379.
    • (1994) Ann Hum Genet. , vol.58 , pp. 369-379
    • Brenn, T.1
  • 39
    • 0025879989 scopus 로고
    • Genetic and environmental contributions to cholesterol and its subfractions in 11-year-old twins: The Medical College of Virginia twin study
    • Bodurtha JN, Chen CW, Mosteller M, Nance WE, Schieken R, Segrest J. Genetic and environmental contributions to cholesterol and its subfractions in 11-year-old twins: the Medical College of Virginia twin study. Arterioscler Thromb. 1991;11:844-850.
    • (1991) Arterioscler Thromb. , vol.11 , pp. 844-850
    • Bodurtha, J.N.1    Chen, C.W.2    Mosteller, M.3    Nance, W.E.4    Schieken, R.5    Segrest, J.6
  • 40
    • 0020506022 scopus 로고
    • Plasma lipids in twins: Environmental and genetic influences
    • Whitfield JB, Martin NG. Plasma lipids in twins: environmental and genetic influences. Atherosclerosis. 1983;48:265-277.
    • (1983) Atherosclerosis , vol.48 , pp. 265-277
    • Whitfield, J.B.1    Martin, N.G.2
  • 41
    • 0031443532 scopus 로고    scopus 로고
    • Heritability analysis of lipids and three gene loci in twins link the macrophage scavenger receptor to HDL cholesterol concentrations
    • Knoblauch H, Busjahn A, Münter S, Nagy Z, Faulhaber H-D, Schuster H, Luft FC. Heritability analysis of lipids and three gene loci in twins link the macrophage scavenger receptor to HDL cholesterol concentrations. Arterioscler Thromb Vasc Biol. 1997;17:2054-2060.
    • (1997) Arterioscler Thromb Vasc Biol. , vol.17 , pp. 2054-2060
    • Knoblauch, H.1    Busjahn, A.2    Münter, S.3    Nagy, Z.4    Faulhaber, H.-D.5    Schuster, H.6    Luft, F.C.7
  • 42
    • 0024556170 scopus 로고
    • Genetic heritability and common environmental components of resting and stressed blood pressures, lipids and body mass index in Utah pedigrees and twins
    • Hunt SC, Hasstedt SJ, Kuida H, Stults BM, Hopkins PN, Williams RR. Genetic heritability and common environmental components of resting and stressed blood pressures, lipids and body mass index in Utah pedigrees and twins. Am J Epidemiol. 1989;129:625-638.
    • (1989) Am J Epidemiol. , vol.129 , pp. 625-638
    • Hunt, S.C.1    Hasstedt, S.J.2    Kuida, H.3    Stults, B.M.4    Hopkins, P.N.5    Williams, R.R.6
  • 43
    • 0027156497 scopus 로고
    • Genetic and environmental covariance of serum cholesterol and blood pressure in female twins
    • Williams PD, Puddley IB, Martin NG, Beilin LJ. Genetic and environmental covariance of serum cholesterol and blood pressure in female twins. Atherosclerosis. 1993;100:19-31.
    • (1993) Atherosclerosis , vol.100 , pp. 19-31
    • Williams, P.D.1    Puddley, I.B.2    Martin, N.G.3    Beilin, L.J.4
  • 44
    • 0023126573 scopus 로고
    • Risk factors for coronary heart disease in adult female twins: Genetic heritability and shared environmental influences
    • Austin MA, King MC, Bawol RD, Hulley SB, Friedman GD. Risk factors for coronary heart disease in adult female twins: genetic heritability and shared environmental influences. Am J Epidemiol. 1987;125: 308-318.
    • (1987) Am J Epidemiol. , vol.125 , pp. 308-318
    • Austin, M.A.1    King, M.C.2    Bawol, R.D.3    Hulley, S.B.4    Friedman, G.D.5
  • 45
    • 0020671881 scopus 로고
    • Genetics of coronary heart disease
    • Steinberg AG, Bearn AG, Motulsky AG, Childs B, eds. Philadelphia, Pa: Saunders
    • Berg K. Genetics of coronary heart disease. In: Steinberg AG, Bearn AG, Motulsky AG, Childs B, eds. Progress in Medical Genetics, Volume V. Philadelphia, Pa: Saunders; 1983:35-90.
    • (1983) Progress in Medical Genetics , vol.5 , pp. 35-90
    • Berg, K.1
  • 46
    • 0031029533 scopus 로고    scopus 로고
    • The age dependency of gene expression for plasma lipids, lipoproteins, and apolipoproteins
    • Snieder H, van Doornen LJP, Boomsma DI. The age dependency of gene expression for plasma lipids, lipoproteins, and apolipoproteins. Am J Hum Genet. 1997;60:638-650.
    • (1997) Am J Hum Genet. , vol.60 , pp. 638-650
    • Snieder, H.1    Van Doornen, L.J.P.2    Boomsma, D.I.3
  • 48
    • 0026667073 scopus 로고
    • Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations
    • Boerwinkle E, Leffert CC, Lin J, Lackner C, Chiesa G, Hobbs HH. Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. J Clin Invest. 1992;90:52-60.
    • (1992) J Clin Invest. , vol.90 , pp. 52-60
    • Boerwinkle, E.1    Leffert, C.C.2    Lin, J.3    Lackner, C.4    Chiesa, G.5    Hobbs, H.H.6
  • 49
    • 0028854118 scopus 로고
    • Genetic variation in lipoprotein(a) levels in families enriched for coronary artery disease is determined almost entirely by the apolipoprotein(a) gene locus
    • DeMeester CA, Bu X, Gray RJ, Lusis AJ, Rotter JI. Genetic variation in lipoprotein(a) levels in families enriched for coronary artery disease is determined almost entirely by the apolipoprotein(a) gene locus. Am J Hum Genet. 1995;56:287-293.
    • (1995) Am J Hum Genet. , vol.56 , pp. 287-293
    • DeMeester, C.A.1    Bu, X.2    Gray, R.J.3    Lusis, A.J.4    Rotter, J.I.5
  • 50
    • 0018874647 scopus 로고
    • On the heritability of serum high density lipoprotein in twins
    • Sistonen P, Ehnholm C. On the heritability of serum high density lipoprotein in twins. Am J Hum Genet. 1980;32:1-7.
    • (1980) Am J Hum Genet. , vol.32 , pp. 1-7
    • Sistonen, P.1    Ehnholm, C.2
  • 51
    • 0021687822 scopus 로고
    • Twins studies of coronary heart disease and its risk factors
    • Berg K. Twins studies of coronary heart disease and its risk factors. Acta Genet Med Gemellol (Roma). 1984;33:349-361.
    • (1984) Acta Genet Med Gemellol (Roma) , vol.33 , pp. 349-361
    • Berg, K.1
  • 53
    • 0023275051 scopus 로고
    • Inheritance of high density lipoprotein and lipoprotein lipase and hepatic lipase activity
    • Kuusi T, Kesäniemi A, Vuoristo M, Miettinen TA, Koskenvuo M. Inheritance of high density lipoprotein and lipoprotein lipase and hepatic lipase activity. Arteriosclerosis. 1987;7:421-425.
    • (1987) Arteriosclerosis. , vol.7 , pp. 421-425
    • Kuusi, T.1    Kesäniemi, A.2    Vuoristo, M.3    Miettinen, T.A.4    Koskenvuo, M.5
  • 55
    • 0023215295 scopus 로고
    • Lifestyle factors affecting intrapair differences of serum apoproteins and cholesterol concentrations in adult identical twins
    • Hayakawa K, Shimizu T, Ohba Y, Tomioka S. Lifestyle factors affecting intrapair differences of serum apoproteins and cholesterol concentrations in adult identical twins. Atherosclerosis. 1987;66:1-9.
    • (1987) Atherosclerosis , vol.66 , pp. 1-9
    • Hayakawa, K.1    Shimizu, T.2    Ohba, Y.3    Tomioka, S.4
  • 56
    • 0018153014 scopus 로고
    • Model-fitting approaches to the analysis of human behavior
    • Eaves LJ, Last KA, Young PA, Martin NG. Model-fitting approaches to the analysis of human behavior. Heredity. 1978;41:249-320.
    • (1978) Heredity , vol.41 , pp. 249-320
    • Eaves, L.J.1    Last, K.A.2    Young, P.A.3    Martin, N.G.4
  • 57
    • 0026778869 scopus 로고
    • Evidence for independent genetic influences on obesity in middle age
    • Fabsitz RR, Carmelli D, Hewitt JK. Evidence for independent genetic influences on obesity in middle age. Int J Obes. 1992;16:657-666.
    • (1992) Int J Obes. , vol.16 , pp. 657-666
    • Fabsitz, R.R.1    Carmelli, D.2    Hewitt, J.K.3
  • 58
    • 0027731460 scopus 로고
    • A genetic and environmental time series analysis of blood pressure in male twins
    • Colletto GM, Cardon LR, Fulker DW. A genetic and environmental time series analysis of blood pressure in male twins. Genet Epidemiol. 1993; 10:533-538.
    • (1993) Genet Epidemiol. , vol.10 , pp. 533-538
    • Colletto, G.M.1    Cardon, L.R.2    Fulker, D.W.3
  • 60
    • 0002373584 scopus 로고
    • Genetic developmental trends in blood pressure levels, and blood pressure reactivity to stress
    • Turner JR, Cardon LR, Hewitt JK, eds. New York, NY: Plenum
    • Snieder H, van Doornen LJP, Boomsma DI. Genetic developmental trends in blood pressure levels, and blood pressure reactivity to stress. In: Turner JR, Cardon LR, Hewitt JK, eds. Behavior Genetic Approaches in Behavioral Medicine. New York, NY: Plenum; 1995: 105-130.
    • (1995) Behavior Genetic Approaches in Behavioral Medicine , pp. 105-130
    • Snieder, H.1    Van Doornen, L.J.P.2    Boomsma, D.I.3
  • 63
    • 0027715232 scopus 로고
    • Lipid data from NHLBI veteran twins: Interpreting genetic analyses when model assumptions fail
    • Williams CJ, Wijesiri UL. Lipid data from NHLBI veteran twins: interpreting genetic analyses when model assumptions fail. Genet Epidemiol. 1993;10:551-556.
    • (1993) Genet Epidemiol. , vol.10 , pp. 551-556
    • Williams, C.J.1    Wijesiri, U.L.2
  • 64
    • 0024454108 scopus 로고
    • Genetics of variability of CHD risk
    • Sing CF, Moll PP. Genetics of variability of CHD risk. Int J Epidemiol. 1989;18:s183-s195.
    • (1989) Int J Epidemiol. , vol.18
    • Sing, C.F.1    Moll, P.P.2
  • 65
    • 0025666368 scopus 로고
    • Genetics of atherosclerosis
    • Sing CF, Moll PP. Genetics of atherosclerosis. Annu Rev Genet. 1990; 24:171-189.
    • (1990) Annu Rev Genet. , vol.24 , pp. 171-189
    • Sing, C.F.1    Moll, P.P.2
  • 66
    • 0024322395 scopus 로고
    • Human genetics and coronary heart disease: A public health perspective
    • Hopkins PN, Williams RR. Human genetics and coronary heart disease: a public health perspective. Annu Rev Nutr. 1989;9:303-345.
    • (1989) Annu Rev Nutr. , vol.9 , pp. 303-345
    • Hopkins, P.N.1    Williams, R.R.2
  • 68
    • 0027096268 scopus 로고
    • Biological complexity and strategies for finding DNa variations responsible for inter-individual variation in risk of a common chronic disease, coronary artery disease
    • Sing CF, Haviland MB, Templeton AR, Zerba KE, Reilly SL. Biological complexity and strategies for finding DNA variations responsible for inter-individual variation in risk of a common chronic disease, coronary artery disease. Ann Med. 1992;24:539-547.
    • (1992) Ann Med. , vol.24 , pp. 539-547
    • Sing, C.F.1    Haviland, M.B.2    Templeton, A.R.3    Zerba, K.E.4    Reilly, S.L.5
  • 69
    • 0028036410 scopus 로고
    • Genetic and environmental correlations among serum lipids and apolipoproteins in elderly twins reared together and apart
    • Heller DA, Pedersen LD, de Faire U, McClearn GE. Genetic and environmental correlations among serum lipids and apolipoproteins in elderly twins reared together and apart. Am J Hum Genet. 1995;5:1255-1267.
    • (1995) Am J Hum Genet. , vol.5 , pp. 1255-1267
    • Heller, D.A.1    Pedersen, L.D.2    De Faire, U.3    McClearn, G.E.4
  • 72
    • 0019413071 scopus 로고
    • Estimates of the genetical and environmental determinants of serum lipids and lipoprotein concentrations in Brazilian twins
    • Colletto GMDD, Krieger H, Magalhaes JS. Estimates of the genetical and environmental determinants of serum lipids and lipoprotein concentrations in Brazilian twins. Hum Hered. 1981;31:232-237.
    • (1981) Hum Hered. , vol.31 , pp. 232-237
    • Colletto, G.M.D.D.1    Krieger, H.2    Magalhaes, J.S.3
  • 73
    • 0027769346 scopus 로고
    • A genetic analysis of cardiovascular disease risk factor clustering in adult female twins
    • Mosteller M. A genetic analysis of cardiovascular disease risk factor clustering in adult female twins. Genes Epidemiol. 1993;10:569-574.
    • (1993) Genes Epidemiol. , vol.10 , pp. 569-574
    • Mosteller, M.1
  • 76
    • 0012219475 scopus 로고    scopus 로고
    • Tel-Aviv-Heidelberg three generation offspring study: Genetic and environment sources of variation and covariation among plasma lipids, lipoproteins and apolipoproteins
    • Livshits G, Vainder M, Graff E, Blettner M, Schettler G, Brunner D. Tel-Aviv-Heidelberg three generation offspring study: genetic and environment sources of variation and covariation among plasma lipids, lipoproteins and apolipoproteins. Am J Hum Biol. 1997;9:357-370.
    • (1997) Am J Hum Biol. , vol.9 , pp. 357-370
    • Livshits, G.1    Vainder, M.2    Graff, E.3    Blettner, M.4    Schettler, G.5    Brunner, D.6
  • 79
    • 2142790963 scopus 로고
    • Genetic linkage in graded human characters
    • Penrose GS. Genetic linkage in graded human characters. Ann Eugen. 1938;8:223-237.
    • (1938) Ann Eugen. , vol.8 , pp. 223-237
    • Penrose, G.S.1
  • 80
    • 0015309467 scopus 로고
    • The investigation of linkage between a quantitative trait and a marker locus
    • Haseman JK, Elston RC. The investigation of linkage between a quantitative trait and a marker locus. Behav Genet. 1972;2:3-19.
    • (1972) Behav Genet. , vol.2 , pp. 3-19
    • Haseman, J.K.1    Elston, R.C.2
  • 83
    • 0030873884 scopus 로고    scopus 로고
    • Testing association between candidate-gene markers and phenotype in related individuals, by use of estimating equations
    • Trégouët D-A, Ducimetière P, Tiret L. Testing association between candidate-gene markers and phenotype in related individuals, by use of estimating equations. Am J Hum Genet. 1997;61:189-199.
    • (1997) Am J Hum Genet. , vol.61 , pp. 189-199
    • Trégouët, D.-A.1    Ducimetière, P.2    Tiret, L.3
  • 84
    • 0031912715 scopus 로고    scopus 로고
    • A sibship test for linkage in the presence of association: The sib transmission/disequilibrium test
    • Spielman RS, Ewens WJ. A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. Am J Hum Genet. 1998;62:450-458.
    • (1998) Am J Hum Genet. , vol.62 , pp. 450-458
    • Spielman, R.S.1    Ewens, W.J.2
  • 85
    • 0033366671 scopus 로고    scopus 로고
    • Combined linkage and association sib-pair analysis for quantitative traits
    • Fulker DW, Cherny SS, Sham PC, Hewitt JK. Combined linkage and association sib-pair analysis for quantitative traits. Am J Hum Genet. 1999;64:259-267.
    • (1999) Am J Hum Genet. , vol.64 , pp. 259-267
    • Fulker, D.W.1    Cherny, S.S.2    Sham, P.C.3    Hewitt, J.K.4
  • 86
    • 0343151851 scopus 로고
    • Quantitative trait loci: Mapping genes for complex traits
    • Turner JR, Cardon LR, Hewitt JK, eds. New York, NY: Plenum
    • Cardon LR. Quantitative trait loci: mapping genes for complex traits. In: Turner JR, Cardon LR, Hewitt JK, eds. Behavior Genetic Approaches in Behavioral Medicine. New York, NY: Plenum; 1995:237-250.
    • (1995) Behavior Genetic Approaches in Behavioral Medicine , pp. 237-250
    • Cardon, L.R.1
  • 87
    • 84953499404 scopus 로고
    • Power and robustness of sib-pair linkage tests and extension to larger sibships
    • Blackwelder WC, Elston RC. Power and robustness of sib-pair linkage tests and extension to larger sibships. Commun Stat Theor Methodol. 1982;11:449-484.
    • (1982) Commun Stat Theor Methodol. , vol.11 , pp. 449-484
    • Blackwelder, W.C.1    Elston, R.C.2
  • 88
    • 0029001682 scopus 로고
    • Extreme discordant sib pairs for mapping quantitative trait loci in humans
    • Risch N, Zhang H. Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science. 1995;268:1584-1589.
    • (1995) Science , vol.268 , pp. 1584-1589
    • Risch, N.1    Zhang, H.2
  • 89
    • 0025170498 scopus 로고
    • A multivariate method for detecting genetic linkage, with application to a pedigree with an adverse lipoprotein phenotype
    • Amos CI, Elston RC, Bonney GE, Keats BJB, Berenson GS. A multivariate method for detecting genetic linkage, with application to a pedigree with an adverse lipoprotein phenotype. Am J Hum Genet. 1990;47:247-254.
    • (1990) Am J Hum Genet. , vol.47 , pp. 247-254
    • Amos, C.I.1    Elston, R.C.2    Bonney, G.E.3    Keats, B.J.B.4    Berenson, G.S.5
  • 90
    • 0025308175 scopus 로고
    • Estimation of individual genetic and environmental factor scores
    • Boomsma DI, Molenaar PCM, Orlebeke JF. Estimation of individual genetic and environmental factor scores. Genet Epidemiol. 1990;7: 83-91.
    • (1990) Genet Epidemiol. , vol.7 , pp. 83-91
    • Boomsma, D.I.1    Molenaar, P.C.M.2    Orlebeke, J.F.3
  • 91
    • 0025878544 scopus 로고
    • Estimation of individual genetic and environmental profiles in longitudinal designs
    • Boomsma DI, Molenaar PCM, Dolan CV. Estimation of individual genetic and environmental profiles in longitudinal designs. Behav Genet. 1991;21:241-253.
    • (1991) Behav Genet. , vol.21 , pp. 241-253
    • Boomsma, D.I.1    Molenaar, P.C.M.2    Dolan, C.V.3
  • 92
    • 0029880136 scopus 로고    scopus 로고
    • Using multivariate genetic modeling to detect pleiotropic quantitative trait loci
    • Boomsma DI. Using multivariate genetic modeling to detect pleiotropic quantitative trait loci. Behav Genet. 1996;26:161-166.
    • (1996) Behav Genet. , vol.26 , pp. 161-166
    • Boomsma, D.I.1
  • 93
    • 0032411943 scopus 로고    scopus 로고
    • A comparison of power to detect a QTL in sib-pair data using multivariate phenotypes, mean phenotypes, and factor-scores
    • Boomsma DI, Dolan CV. A comparison of power to detect a QTL in sib-pair data using multivariate phenotypes, mean phenotypes, and factor-scores. Behav Genet. 1999;28:329-340.
    • (1999) Behav Genet. , vol.28 , pp. 329-340
    • Boomsma, D.I.1    Dolan, C.V.2
  • 94
    • 0001873194 scopus 로고    scopus 로고
    • Multivariate QTL analysis using structural equation modeling: A look at power under simple conditions
    • Spector TD, Snieder H, MacGregor AJ, eds. London, England: Greenwich Medical Ltd
    • Boomsma DI, Dolan CV. Multivariate QTL analysis using structural equation modeling: a look at power under simple conditions. In: Spector TD, Snieder H, MacGregor AJ, eds. Advances in Twin and Sib-Pair Analysis. London, England: Greenwich Medical Ltd; 1999:203-218.
    • (1999) Advances in Twin and Sib-Pair Analysis , pp. 203-218
    • Boomsma, D.I.1    Dolan, C.V.2
  • 95
    • 0030863012 scopus 로고    scopus 로고
    • Evidence that the apolipoprotein e genotype effects on lipid levels can change with age in males: A longitudinal analysis
    • Jarvik GP, Goode EL, Austin MA, Auwerx J, Deeb S, Schellenberg GD, Reed T. Evidence that the apolipoprotein E genotype effects on lipid levels can change with age in males: a longitudinal analysis. Am J Hum Genet. 1997;61:171-181.
    • (1997) Am J Hum Genet. , vol.61 , pp. 171-181
    • Jarvik, G.P.1    Goode, E.L.2    Austin, M.A.3    Auwerx, J.4    Deeb, S.5    Schellenberg, G.D.6    Reed, T.7
  • 96
    • 0019433388 scopus 로고
    • Apparent influence of marker genotypes on variation in serum cholesterol in monozygotic twins
    • Magnus P, Berg K, Borresen A-L, Nance WE. Apparent influence of marker genotypes on variation in serum cholesterol in monozygotic twins. Clin Genet. 1981;19:67-70.
    • (1981) Clin Genet. , vol.19 , pp. 67-70
    • Magnus, P.1    Berg, K.2    Borresen, A.-L.3    Nance, W.E.4
  • 97
    • 0020578092 scopus 로고
    • Do the MN and JK systems influence environmental variability in serum lipid levels?
    • Martin NG, Rowell DM, Whitfield JB. Do the MN and JK systems influence environmental variability in serum lipid levels? Clin Genet. 1983;24:1-14.
    • (1983) Clin Genet. , vol.24 , pp. 1-14
    • Martin, N.G.1    Rowell, D.M.2    Whitfield, J.B.3
  • 99
    • 0000501839 scopus 로고    scopus 로고
    • Gene-environment interaction and twin studies
    • Spector TD, Snieder H, MacGregor AJ, eds. London, England: Greenwich Medical Ltd
    • Martin NG. Gene-environment interaction and twin studies. In: Spector TD, Snieder H, MacGregor AJ, eds. Advances in Twin and Sib-Pair Analysis. London, England: Greenwich Medical Ltd; 1999:143-150.
    • (1999) Advances in Twin and Sib-Pair Analysis , pp. 143-150
    • Martin, N.G.1
  • 101
    • 0027271857 scopus 로고
    • Genetics of LDL subclass phenotypes in women twins: Concordance, heritability, and commingling analysis
    • Austin MA, Newman B, Selby JV, Edwards K, Mayer EJ, Krauss RM. Genetics of LDL subclass phenotypes in women twins: concordance, heritability, and commingling analysis. Arterioscler Thromb. 1993;13:687-695.
    • (1993) Arterioscler Thromb. , vol.13 , pp. 687-695
    • Austin, M.A.1    Newman, B.2    Selby, J.V.3    Edwards, K.4    Mayer, E.J.5    Krauss, R.M.6


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