Sensitization of the adenylyl cyclase system in cloned κ-opioid receptor-transfected cells following sustained agonist treatment: A chimeric study using G protein α(i2)/α(q) subunits

Japanese Journal of Pharmacology

Volumn 81, Issue 4, 1999, Pages 353-361

  Nakagawa, Takayuki ^a   Ozawa, Tohru ^a   Watanabe, Takeshi ^a   Minami, Masabumi ^a   Satoh, Masamichi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Opioid receptor; Adenylyl cyclase; Chimeric G protein subunit; CHO cell; Sensitization

Indexed keywords

ADENYLATE CYCLASE; CHIMERIC PROTEIN; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; NORBINALTORPHIMINE; PERTUSSIS TOXIN;

ANIMAL CELL; ARTICLE; CHINESE HAMSTER; CHO CELL; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; ENZYME ANALYSIS; ENZYME INHIBITION; IMMUNOBLOTTING; NONHUMAN; RAT; SENSITIZATION;

ADENYLATE CYCLASE; ADENYLATE CYCLASE TOXIN; ANIMALS; BENZENEACETAMIDES; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; CYCLIC AMP; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HETEROTRIMERIC GTP-BINDING PROTEINS; IMMUNOBLOTTING; MUTATION; PERTUSSIS TOXIN; PROTO-ONCOGENE PROTEINS; PYRROLIDINES; RATS; RECEPTORS, OPIOID, KAPPA; RECOMBINANT FUSION PROTEINS; VIRULENCE FACTORS, BORDETELLA;

EID: 0033395487     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.81.353     Document Type: Article

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