Synthesis and pharmacological properties of novel benzamide derivatives acting as ligands to the 5-hydroxytryptamine 4 (5-HT4) receptor

European Journal of Medicinal Chemistry

Volumn 34, Issue 12, 1999, Pages 1101-1108

  Itoh, Katsuhiko ^a   Tomozane, Hideo ^a   Hakira, Hidetoshi ^a   Sonda, Shuji ^a   Asano, Kiyoshi ^a   Fujimura, Masatake ^a   Sato, Noriko ^a   Haga, Keiichiro ^a   Kawakita, Takeshi ^a  

^a Yoshitomi Pharmaceutical Industries Ltd   (Japan)

Author keywords

5 HT3 receptor antagonism; 5 HT4 receptor agonism; 5 HT4 receptor agonist; Gastrointestinal motility; N 1 5 (1 methylindol 3 ylcarbonylamino)pentyl piperidin 4 ylmethyl benzamide

Indexed keywords

BENZAMIDE DERIVATIVE; PROKINETIC AGENT; SEROTONIN 4 AGONIST; UNCLASSIFIED DRUG; Y 34959;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASCENDING COLON; DOG; DRUG ACTIVITY; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GUINEA PIG; MALE; NONHUMAN; RECEPTOR AFFINITY; STOMACH ANTRUM; STOMACH MOTILITY;

EID: 0033392859     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(99)00125-7     Document Type: Article

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