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Volumn 24, Issue 6, 1999, Pages 397-408

Fluvastatin in combination with cyclosporin in renal transplant recipients: A review of clinical and safety experience

Author keywords

[No Author keywords available]

Indexed keywords

ANTILIPEMIC AGENT; AZATHIOPRINE; CHOLESTEROL; CYCLOSPORIN; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PREDNISOLONE; TRIACYLGLYCEROL;

EID: 0033392760     PISSN: 02694727     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2710.1999.00252.x     Document Type: Review
Times cited : (48)

References (90)
  • 1
    • 0020619251 scopus 로고
    • A randomized clinical trial of cyclosporine in cadaveric renal transplantation
    • 1. Stiller CR, for the Canadian Multicenter Transplant Study Group. (1983) A randomized clinical trial of cyclosporine in cadaveric renal transplantation. New England Journal of Medicine, 309, 809-816.
    • (1983) New England Journal of Medicine , vol.309 , pp. 809-816
    • Stiller, C.R.1
  • 2
    • 0022261468 scopus 로고
    • Results of the Minnesota randomized prospective trial of cyclosporine versus azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients
    • 2. Sutherland DER, Fryd DS, Strand MH, et al. (1985) Results of the Minnesota randomized prospective trial of cyclosporine versus azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients. American Journal of Kidney Disease, V, 318-327.
    • (1985) American Journal of Kidney Disease , vol.5 , pp. 318-327
    • Sutherland, D.E.R.1    Fryd, D.S.2    Strand, M.H.3
  • 5
    • 0032968407 scopus 로고    scopus 로고
    • Cardiovascular morbidity and risk factors in renal transplant patients
    • 5. Aakhus S, Dahl K, Widerøe TE. (1999) Cardiovascular morbidity and risk factors in renal transplant patients. Nephrology, Dialysis, Transplantation, 14, 648-654.
    • (1999) Nephrology, Dialysis, Transplantation , vol.14 , pp. 648-654
    • Aakhus, S.1    Dahl, K.2    Widerøe, T.E.3
  • 6
    • 0026335235 scopus 로고
    • Causes of renal allograft loss: Progress in the 1980s, challenge for the 1990s
    • 6. Schweitzer EJ, Matas AJ, Gillingham KJ, et al. (1991) Causes of renal allograft loss: progress in the 1980s, challenge for the 1990s. Annals of Surgery, 214, 679-688.
    • (1991) Annals of Surgery , vol.214 , pp. 679-688
    • Schweitzer, E.J.1    Matas, A.J.2    Gillingham, K.J.3
  • 7
    • 0026593243 scopus 로고
    • Serum cholesterol, blood pressure, cigarette smoking and death from coronary heart disease. Overall findings and differences by age for 316,099 white men. Multiple risk factor intervention trial research group
    • 7. Neaton JD, Wentworth DF. (1992) Serum cholesterol, blood pressure, cigarette smoking and death from coronary heart disease. Overall findings and differences by age for 316,099 white men. Multiple Risk Factor Intervention Trial Research Group. Archives of Internal Medicine, 152, 56-64.
    • (1992) Archives of Internal Medicine , vol.152 , pp. 56-64
    • Neaton, J.D.1    Wentworth, D.F.2
  • 8
    • 0025633984 scopus 로고
    • The prevalence of hyperlipidemia in renal transplant recipients
    • 8. Bittar AE, Ratcliffe PJ, Richardson AJ, et al. (1990) The prevalence of hyperlipidemia in renal transplant recipients. Transplantation, 50, 987-992.
    • (1990) Transplantation , vol.50 , pp. 987-992
    • Bittar, A.E.1    Ratcliffe, P.J.2    Richardson, A.J.3
  • 9
    • 0026031716 scopus 로고
    • Lipid abnormalities in renal disease
    • 9. Appel GA. (1991) Lipid abnormalities in renal disease. Kidney International, 39, 169-183.
    • (1991) Kidney International , vol.39 , pp. 169-183
    • Appel, G.A.1
  • 12
    • 0024342915 scopus 로고
    • Lipid abnormalities in cyclosporine-prednisolone-treated renal transplant recipients
    • 12. Vathsala A, Weinberg RB, Schoenberg L, et al. (1989) Lipid abnormalities in cyclosporine-prednisolone-treated renal transplant recipients. Transplantation, 48, 37-43.
    • (1989) Transplantation , vol.48 , pp. 37-43
    • Vathsala, A.1    Weinberg, R.B.2    Schoenberg, L.3
  • 14
    • 0023200179 scopus 로고
    • Persistent hyperlipidemia in renal transplant patients
    • 14. Kasiske BL, Umen AJ. (1987) Persistent hyperlipidemia in renal transplant patients. Medicine, 66, 309-316.
    • (1987) Medicine , vol.66 , pp. 309-316
    • Kasiske, B.L.1    Umen, A.J.2
  • 15
    • 0031019711 scopus 로고    scopus 로고
    • Treatment of hyperlipidemia in renal transplant recipients
    • 15. Arnadottir M, Berg A-L. (1997) Treatment of hyperlipidemia in renal transplant recipients. Transplantation, 63, 339-345.
    • (1997) Transplantation , vol.63 , pp. 339-345
    • Arnadottir, M.1    Berg, A.-L.2
  • 16
    • 0002594877 scopus 로고
    • Alterations in lipid and carbohydrate metabolism attributable to cyclosporin A in renal transplant recipients
    • 16. Harris KPG, Russell GI, Parvin SD, Veitch PS, Walls J. (1986) Alterations in lipid and carbohydrate metabolism attributable to cyclosporin A in renal transplant recipients. British Medical Journal, 292, 16.
    • (1986) British Medical Journal , vol.292 , pp. 16
    • Harris, K.P.G.1    Russell, G.I.2    Parvin, S.D.3    Veitch, P.S.4    Walls, J.5
  • 18
    • 0028322177 scopus 로고
    • Relation of cyclosporine blood levels to adverse effects on lipoproteins
    • 18. Kuster GM, Drexel H, Bleisch JA, et al. (1994) Relation of cyclosporine blood levels to adverse effects on lipoproteins. Transplantation, 57, 1479-1483.
    • (1994) Transplantation , vol.57 , pp. 1479-1483
    • Kuster, G.M.1    Drexel, H.2    Bleisch, J.A.3
  • 19
    • 0016601570 scopus 로고
    • The arterial lesions in the cause of renal allograft rejection
    • 19. Callard P, Bedrossian J, Idatte JM, et al. (1975) The arterial lesions in the cause of renal allograft rejection. Advances in Nephrology, 5, 333-353.
    • (1975) Advances in Nephrology , vol.5 , pp. 333-353
    • Callard, P.1    Bedrossian, J.2    Idatte, J.M.3
  • 20
    • 0032911110 scopus 로고    scopus 로고
    • Early graft function and patient survival following cadaveric renal transplantation
    • 20. Woo YM, Jardine AG, Clark AF, et al. (1999) Early graft function and patient survival following cadaveric renal transplantation. Kidney International, 55, 692-699.
    • (1999) Kidney International , vol.55 , pp. 692-699
    • Woo, Y.M.1    Jardine, A.G.2    Clark, A.F.3
  • 22
    • 0023832495 scopus 로고
    • The effect of food and cholestyramine on the absorption of cyclosporine in cardiac transplant recipients
    • 22. Keogh A, Day R, Critchley L, Duggin G, Baron D. (1988) The effect of food and cholestyramine on the absorption of cyclosporine in cardiac transplant recipients. Transplant Proceedings, 20, 27-30.
    • (1988) Transplant Proceedings , vol.20 , pp. 27-30
    • Keogh, A.1    Day, R.2    Critchley, L.3    Duggin, G.4    Baron, D.5
  • 23
    • 0028922898 scopus 로고
    • Effects of nicotinic acid and lovastatin in renal transplant patients: A prospective, randomized, open-labelled crossover trial
    • 23. Lal SM, Hewett JE, Petroski GF, Van Stone JC, Ross G. (1995) Effects of nicotinic acid and lovastatin in renal transplant patients: a prospective, randomized, open-labelled crossover trial. American Journal of Kidney Diseases, 25, 616-622.
    • (1995) American Journal of Kidney Diseases , vol.25 , pp. 616-622
    • Lal, S.M.1    Hewett, J.E.2    Petroski, G.F.3    Van Stone, J.C.4    Ross, G.5
  • 24
    • 0026088892 scopus 로고
    • Expanded clinical evaluation of lovastatin (EXCEL) study results. I. Efficacy in modifying plasma lipoproteins and adverse event profile in 8245 patients with moderate hypercholesterolemia
    • 24. Bradford RH, Shear CL, Chremos AN, et al. (1991) Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. I. Efficacy in modifying plasma lipoproteins and adverse event profile in 8245 patients with moderate hypercholesterolemia. Archives of Internal Medicine, 151, 43-49.
    • (1991) Archives of Internal Medicine , vol.151 , pp. 43-49
    • Bradford, R.H.1    Shear, C.L.2    Chremos, A.N.3
  • 25
    • 0026540161 scopus 로고
    • Comparative effects of simvastatin and lovastatin in patients with hypercholesterolemia. The simvastatin and lovastatin multicenter study participants
    • 25. Farmer JA, Washington LC, Jones PH, Shapiro DR, Goto AM, Mantell G. (1992) Comparative effects of simvastatin and lovastatin in patients with hypercholesterolemia. The Simvastatin and Lovastatin Multicenter Study Participants. Clinical Therapy, 14, 708-717.
    • (1992) Clinical Therapy , vol.14 , pp. 708-717
    • Farmer, J.A.1    Washington, L.C.2    Jones, P.H.3    Shapiro, D.R.4    Goto, A.M.5    Mantell, G.6
  • 26
    • 0027733908 scopus 로고
    • Efficacy and tolerability of simvastatin 20 mg vs pravastatin 20 mg in patients with primary hypercholesterolemia. European study group
    • 26. Lambrecht LF, Malini PL. (1993) Efficacy and tolerability of simvastatin 20 mg vs pravastatin 20 mg in patients with primary hypercholesterolemia. European Study Group. Acta Cardiologica, 48, 541-554.
    • (1993) Acta Cardiologica , vol.48 , pp. 541-554
    • Lambrecht, L.F.1    Malini, P.L.2
  • 27
    • 0027457259 scopus 로고
    • A multicenter comparative trial of lovastatin and pravastatin in the treatment of hypercholesterolemia
    • 27. Lovastatin/Pravastatin Study Group. (1993) A multicenter comparative trial of lovastatin and pravastatin in the treatment of hypercholesterolemia. American Journal of Cardiology, 71, 810-815.
    • (1993) American Journal of Cardiology , vol.71 , pp. 810-815
  • 28
    • 0028766683 scopus 로고
    • Fluvastatin in primary hypercholesterolemia. Efficacy and safety in patients at high risk. An analysis of a clinical trial database
    • 28. Peters TK, Muratti EN, Mehra M. (1994) Fluvastatin in primary hypercholesterolemia. efficacy and safety in patients at high risk. An analysis of a clinical trial database. American Journal of Medicine, 96(Suppl. 6A), 79S-83S.
    • (1994) American Journal of Medicine , vol.96 , Issue.SUPPL. 6A
    • Peters, T.K.1    Muratti, E.N.2    Mehra, M.3
  • 29
    • 0027963344 scopus 로고
    • Comparative efficacy and tolerability of 5 and 10 mg simvastatin and 10 mg pravastatin in moderate primary hypercholesterolemia
    • 29. Steinhagen-Thiessen E, on behalf of the Simvastatin Pravastatin European Study Group. (1994) Comparative efficacy and tolerability of 5 and 10 mg simvastatin and 10 mg pravastatin in moderate primary hypercholesterolemia. Cardiology, 85, 244-254.
    • (1994) Cardiology , vol.85 , pp. 244-254
    • Steinhagen-Thiessen, E.1
  • 30
    • 0030841001 scopus 로고    scopus 로고
    • Effects of fluvastatin on coronary atherosclerosis in patients with mild to moderate cholesterol elevations (lipoprotein and coronary atherosclerosis study [LCAS])
    • 30. Herd JA, Ballantyne CM, Farmer JA, et al. (1997) Effects of fluvastatin on coronary atherosclerosis in patients with mild to moderate cholesterol elevations (Lipoprotein and Coronary Atherosclerosis Study [LCAS]). American Journal of Cardiology, 80, 278-286.
    • (1997) American Journal of Cardiology , vol.80 , pp. 278-286
    • Herd, J.A.1    Ballantyne, C.M.2    Farmer, J.A.3
  • 31
    • 0031787156 scopus 로고    scopus 로고
    • Randomised, doubleblind, parallel-group trial of atorvastatin and fluvastatin on plasma lipid levels in patients with untreated hyperlipidaemia
    • 31. Schuster H, Berger J, Luft FC. (1998) Randomised, doubleblind, parallel-group trial of atorvastatin and fluvastatin on plasma lipid levels in patients with untreated hyperlipidaemia. British Journal of Cardiology, 5, 597-602.
    • (1998) British Journal of Cardiology , vol.5 , pp. 597-602
    • Schuster, H.1    Berger, J.2    Luft, F.C.3
  • 32
    • 0030825779 scopus 로고    scopus 로고
    • Fluvastatin lipid-lowering effect in routine practice conditions (FLIRT). Results of a drug surveillance study
    • 32. Beil S, Pfafferott C, Weber M, on behalf of the fluvastatin investigators. (1997) Fluvastatin lipid-lowering effect in routine practice conditions (FLIRT). Results of a drug surveillance study. Clinical Drug Investigations, 14, 146-153.
    • (1997) Clinical Drug Investigations , vol.14 , pp. 146-153
    • Beil, S.1    Pfafferott, C.2    Weber, M.3
  • 33
    • 0031614437 scopus 로고    scopus 로고
    • Effect of diet and fluvastatin treatment on the serum lipid profile of kidney transplant, diabetic recipients: A 1-year follow up
    • 33. Földes K, Makláry E, Vargha P, et al. (1998) Effect of diet and fluvastatin treatment on the serum lipid profile of kidney transplant, diabetic recipients: a 1-year follow up. Transplant International, 11(Suppl. 1), S65-S68.
    • (1998) Transplant International , vol.11 , Issue.SUPPL. 1
    • Földes, K.1    Makláry, E.2    Vargha, P.3
  • 34
    • 0028864694 scopus 로고
    • Effect of fluvastatin on lipoprotein profiles in treating renal transplant recipients with dyslipoproteinemia
    • 34. Li PKT, Mak TWL, Chan TH, Wang A, Lam CWK, Lai KN. (1995) Effect of fluvastatin on lipoprotein profiles in treating renal transplant recipients with dyslipoproteinemia. Transplantation, 60, 652-656.
    • (1995) Transplantation , vol.60 , pp. 652-656
    • Li, P.K.T.1    Mak, T.W.L.2    Chan, T.H.3    Wang, A.4    Lam, C.W.K.5    Lai, K.N.6
  • 35
  • 36
    • 0032533413 scopus 로고    scopus 로고
    • Efficacy and muscle safety of fluvastatin in cyclosporine-treated cardiac and renal transplant recipients, an exercise provocation test
    • 36. Schrama YC, Hené RJ, de Jonge N, et al. (1998) Efficacy and muscle safety of fluvastatin in cyclosporine-treated cardiac and renal transplant recipients, an exercise provocation test. Transplantation, 66, 1175-1181.
    • (1998) Transplantation , vol.66 , pp. 1175-1181
    • Schrama, Y.C.1    Hené, R.J.2    De Jonge, N.3
  • 38
    • 0029947184 scopus 로고    scopus 로고
    • A review of its pharmacology and use in the management of hypercholesterolaemia
    • 38. Plosker GL, Wagstaff AJ, Fluvastatin. (1996) A review of its pharmacology and use in the management of hypercholesterolaemia. Drugs, 51, 433-459.
    • (1996) Drugs , vol.51 , pp. 433-459
    • Plosker, G.L.1    Wagstaff, A.J.2
  • 39
    • 0008889647 scopus 로고    scopus 로고
    • A review of its use in lipid disorders
    • in press
    • 39. Langtry HD, Markham A, Fluvastatin. (1999) A review of its use in lipid disorders. Drugs, in press.
    • (1999) Drugs
    • Langtry, H.D.1    Markham, A.2
  • 41
    • 12644251055 scopus 로고    scopus 로고
    • Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-treated kidney graft patients after multiple doses
    • 41. Olbricht C, Wanner C, Eisenhauer T, et al. (1997) Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-treated kidney graft patients after multiple doses. Clinical Pharmacology and Therapeutics, 62, 311-321.
    • (1997) Clinical Pharmacology and Therapeutics , vol.62 , pp. 311-321
    • Olbricht, C.1    Wanner, C.2    Eisenhauer, T.3
  • 42
    • 0023697436 scopus 로고    scopus 로고
    • Efficacy and long-term adverse effects pattern of lovastatin
    • 42. Tobert JA. (1998) Efficacy and long-term adverse effects pattern of lovastatin. American Journal of Cardiology, 62, 28J-34J.
    • (1998) American Journal of Cardiology , vol.62
    • Tobert, J.A.1
  • 43
    • 0023929374 scopus 로고
    • Rhabdomyolysis and renal injury with lovastatin use. Report of two cases in cardiac transplant recipients
    • 43. Corpier CL, Jones PH, Suki WN, et al. (1988) Rhabdomyolysis and renal injury with lovastatin use. Report of two cases in cardiac transplant recipients. Journal of the American Medical Association, 260, 239-241.
    • (1988) Journal of the American Medical Association , vol.260 , pp. 239-241
    • Corpier, C.L.1    Jones, P.H.2    Suki, W.N.3
  • 46
    • 0027377733 scopus 로고
    • Plasma concentration profiles of simvastatin 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitory activity in kidney transplant recipients with and without ciclosporin
    • 46. Arnadottir M, Eriksson L-O, Thysell H, Karkas JD. (1993) Plasma concentration profiles of simvastatin 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitory activity in kidney transplant recipients with and without ciclosporin. Nephron, 65, 410-413.
    • (1993) Nephron , vol.65 , pp. 410-413
    • Arnadottir, M.1    Eriksson, L.-O.2    Thysell, H.3    Karkas, J.D.4
  • 47
    • 0029040951 scopus 로고
    • Rhabdomyolysis in patients treated with simvastatin and cyclosporin: Role of hepatic cytochrome P450 enzyme system activity
    • 47. Meier C, Stey C, Brack T, Maggiorini M, Risti B, Krahenbuhl S. (1995) Rhabdomyolysis in patients treated with simvastatin and cyclosporin: role of hepatic cytochrome P450 enzyme system activity. Schweizerische Medizinische Wochenschrift, 125, 1342-1346.
    • (1995) Schweizerische Medizinische Wochenschrift , vol.125 , pp. 1342-1346
    • Meier, C.1    Stey, C.2    Brack, T.3    Maggiorini, M.4    Risti, B.5    Krahenbuhl, S.6
  • 49
    • 0031658907 scopus 로고    scopus 로고
    • Rational assessment of the interaction profile of cerivastatin supports its low propensity for drug interactions
    • 49. Muck W. (1998) Rational assessment of the interaction profile of cerivastatin supports its low propensity for drug interactions. Drugs, 56(Suppl. 1), 15-23.
    • (1998) Drugs , vol.56 , Issue.SUPPL. 1 , pp. 15-23
    • Muck, W.1
  • 50
    • 0029101804 scopus 로고
    • Comparative evaluation of the safety and efficacy of HMG-CoA reductase inhibitor monotherapy in the treatment of primary hypercholesterolemia
    • 50. Hsu I, Spinler SA, Johnson NE. (1995) Comparative evaluation of the safety and efficacy of HMG-CoA reductase inhibitor monotherapy in the treatment of primary hypercholesterolemia. Annals of Pharmacotherapy, 29, 743-759.
    • (1995) Annals of Pharmacotherapy , vol.29 , pp. 743-759
    • Hsu, I.1    Spinler, S.A.2    Johnson, N.E.3
  • 51
    • 0025818108 scopus 로고
    • HMG-CoA. Reductase inhibitor-induced myopathy in the rat: Cyclosporine A interaction and mechanism studies
    • 51. Smith PF, Eydelloth RS, Grossman SJ, et al. (1991) HMG-CoA. reductase inhibitor-induced myopathy in the rat: cyclosporine A interaction and mechanism studies. Journal of Pharmacological and Experimental Therapy, 257, 1225-1235.
    • (1991) Journal of Pharmacological and Experimental Therapy , vol.257 , pp. 1225-1235
    • Smith, P.F.1    Eydelloth, R.S.2    Grossman, S.J.3
  • 52
    • 0027327029 scopus 로고
    • Altered disposition of pravastatin following concomitant drug therapy with cyclosporin A in transplant recipients
    • 52. Regazzi MB, Iacona I, Campana C, et al. (1993) Altered disposition of pravastatin following concomitant drug therapy with cyclosporin A in transplant recipients. Transplant Proceedings, 25, 2732-2734.
    • (1993) Transplant Proceedings , vol.25 , pp. 2732-2734
    • Regazzi, M.B.1    Iacona, I.2    Campana, C.3
  • 53
    • 0023921505 scopus 로고
    • Cyclosporine metabolism in human liver: Identification of a cytochrome P450III gene family as the major cyclosporinemetabolizing enzyme explains interactions of cyclosporine with other drugs
    • 53. Kronbach T, Fischer V, Meyer UA. (1988) Cyclosporine metabolism in human liver: identification of a cytochrome P450III gene family as the major cyclosporinemetabolizing enzyme explains interactions of cyclosporine with other drugs. Clinical Pharmacology and Therapeutics, 43, 630-635.
    • (1988) Clinical Pharmacology and Therapeutics , vol.43 , pp. 630-635
    • Kronbach, T.1    Fischer, V.2    Meyer, U.A.3
  • 54
    • 0025944905 scopus 로고
    • Biotransformation of lovastatin. IV. Identification of cytochrome P450, 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes
    • 54. Wang RW, Kari PH, Lu AYH, Thomas PE, Guengerich FP, Vyas KP. (1991) Biotransformation of lovastatin. IV. Identification of cytochrome P450, 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes. Archives of Biochemistry and Biophysics, 290, 355-361.
    • (1991) Archives of Biochemistry and Biophysics , vol.290 , pp. 355-361
    • Wang, R.W.1    Kari, P.H.2    Lu, A.Y.H.3    Thomas, P.E.4    Guengerich, F.P.5    Vyas, K.P.6
  • 55
    • 0030812885 scopus 로고    scopus 로고
    • In vitro metabolism of simvastatin in humans [SBT] identification of metabolizing enzymes and effect of the drugs on hepatic P450s
    • 55. Prueksaritanont T, Gorham LM, Ma B, et al. (1997) In vitro metabolism of simvastatin in humans [SBT] identification of metabolizing enzymes and effect of the drugs on hepatic P450s. Drug Metabolism and Disposition, 25, 1191-1199.
    • (1997) Drug Metabolism and Disposition , vol.25 , pp. 1191-1199
    • Prueksaritanont, T.1    Gorham, L.M.2    Ma, B.3
  • 56
    • 0030893455 scopus 로고    scopus 로고
    • Metabolism of cerivastatin by human liver microsomes in vitro. Characterization of primary metabolic pathways and of cytochrome P450 isozymes involved
    • 56. Boberg M, Angerbauer R, Fey P, et al. (1997) Metabolism of cerivastatin by human liver microsomes in vitro. Characterization of primary metabolic pathways and of cytochrome P450 isozymes involved. Drug Metabolism and Disposition, 25, 321-331.
    • (1997) Drug Metabolism and Disposition , vol.25 , pp. 321-331
    • Boberg, M.1    Angerbauer, R.2    Fey, P.3
  • 57
    • 0031736655 scopus 로고    scopus 로고
    • Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: Are the statins mechanistically similar?
    • 57. Christians U, Jacobsen W, Floren LC. (1998) Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar? Pharmacological Therapy, 80, 1-34.
    • (1998) Pharmacological Therapy , vol.80 , pp. 1-34
    • Christians, U.1    Jacobsen, W.2    Floren, L.C.3
  • 58
    • 0029940090 scopus 로고    scopus 로고
    • HMG-CoA. Reductase mediates the biological effects of retinoic acid on human neuroblastoma cells: Lovastatin specifically targets P-lycoprotein expressing cells
    • 58. Dimitroulakos J, Yeger H. (1996) HMG-CoA. reductase mediates the biological effects of retinoic acid on human neuroblastoma cells: lovastatin specifically targets P-lycoprotein expressing cells. Nature Medicine, 2, 326-333.
    • (1996) Nature Medicine , vol.2 , pp. 326-333
    • Dimitroulakos, J.1    Yeger, H.2
  • 61
    • 0032937343 scopus 로고    scopus 로고
    • The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: Effect on human cytochrome P-450 and implications for metabolic drug interactions
    • 61. Fischer V, Johanson L, Heitz F, et al. (1999) The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: effect on human cytochrome P-450 and implications for metabolic drug interactions. Drug Metabolism and Disposition, 27, 410-416.
    • (1999) Drug Metabolism and Disposition , vol.27 , pp. 410-416
    • Fischer, V.1    Johanson, L.2    Heitz, F.3
  • 62
    • 0000468588 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamic interactions of fluvastatin and their therapeutic implications
    • 62. Appel S, Dingemanse J. (1996) Pharmacokinetics and pharmacodynamic interactions of fluvastatin and their therapeutic implications. Review of Contemporary Pharmacotherapy, 7, 167-182.
    • (1996) Review of Contemporary Pharmacotherapy , vol.7 , pp. 167-182
    • Appel, S.1    Dingemanse, J.2
  • 63
    • 0030463459 scopus 로고    scopus 로고
    • Evaluation of fluvastatin in the treatment of hypercholesterolemia in renal transplant recipients taking cyclosporine
    • 63. Goldberg R, Roth D. (1996) Evaluation of fluvastatin in the treatment of hypercholesterolemia in renal transplant recipients taking cyclosporine. Transplantation, 62, 1559-1564.
    • (1996) Transplantation , vol.62 , pp. 1559-1564
    • Goldberg, R.1    Roth, D.2
  • 65
  • 66
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease. The scandinavian simvastatin survival study (4S)
    • 66. Scandinavian Simvastatin Survival Study Group. (1994) Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease. The Scandinavian Simvastatin Survival Study (4S). Lancet, 344, 1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 67
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • 67. Shepherd J, Cobbe SM, Ford I, et al. (1995) Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. New England Journal of Medicine, 333, 1301-1307.
    • (1995) New England Journal of Medicine , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3
  • 68
    • 0342981862 scopus 로고    scopus 로고
    • The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
    • 68. Sacks FM, Pfeffer MA, Moye LA, et al. (1996) The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. New England Journal of Medicine, 335, 1001-1009.
    • (1996) New England Journal of Medicine , vol.335 , pp. 1001-1009
    • Sacks, F.M.1    Pfeffer, M.A.2    Moye, L.A.3
  • 69
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels. Results of AFCAPS/ TexCAPS
    • 69. Downs JR, Clearfield M, Weis S, et al. for the AFCAPS/ TexCAPS Research Group. (1998) Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels. Results of AFCAPS/ TexCAPS. Journal of the American Medical Association, 279, 1615-1621.
    • (1998) Journal of the American Medical Association , vol.279 , pp. 1615-1621
    • Downs, J.R.1    Clearfield, M.2    Weis, S.3
  • 70
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
    • 70. The Long-term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. (1998) Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. New England Journal of Medicine, 339, 1349-1357.
    • (1998) New England Journal of Medicine , vol.339 , pp. 1349-1357
  • 71
    • 0032904753 scopus 로고    scopus 로고
    • A randomized placebo controlled trial of fluvastatin for prevention of restenosis after successful coronary balloon angioplasty: Final results of the fluvastatin angiographic restenosis (FLARE) trial
    • 71. Serruys PW, Foley DP, Jackson G, et al. on behalf of the FLARE study group. (1999) A randomized placebo controlled trial of fluvastatin for prevention of restenosis after successful coronary balloon angioplasty: final results of the fluvastatin angiographic restenosis (FLARE) trial. European Heart Journal, 20, 58-69.
    • (1999) European Heart Journal , vol.20 , pp. 58-69
    • Serruys, P.W.1    Foley, D.P.2    Jackson, G.3
  • 72
    • 0029565625 scopus 로고
    • Impact of serum lipids on long-term graft and patient survival after renal transplantation
    • 72. Bumgardner GL, Wilson GA, Tso PL, et al. (1995) Impact of serum lipids on long-term graft and patient survival after renal transplantation. Transplantation, 60, 1418-1421.
    • (1995) Transplantation , vol.60 , pp. 1418-1421
    • Bumgardner, G.L.1    Wilson, G.A.2    Tso, P.L.3
  • 76
    • 0033058564 scopus 로고    scopus 로고
    • No clinical evidence of hyperlipidemia as a risk factor for chronic renal allograft failure
    • 76. Hillebrand GF, Schlosser S, Schneeberger H, et al. (1999) No clinical evidence of hyperlipidemia as a risk factor for chronic renal allograft failure. Transplant Proceedings, 31, 1391-1392.
    • (1999) Transplant Proceedings , vol.31 , pp. 1391-1392
    • Hillebrand, G.F.1    Schlosser, S.2    Schneeberger, H.3
  • 78
    • 0030826180 scopus 로고    scopus 로고
    • Simvastatin reduces graft vessel disease and mortality after heart transplantation, a four-year randomized trial
    • 78. Wenke K, MeiSeries B, Thiery J, et al. (1997) Simvastatin reduces graft vessel disease and mortality after heart transplantation, a four-year randomized trial. Circulation, 96, 1398-1402.
    • (1997) Circulation , vol.96 , pp. 1398-1402
    • Wenke, K.1    MeiSeries, B.2    Thiery, J.3
  • 79
    • 0025778512 scopus 로고
    • Hypercholesterolemia in long-term survivors of heart transplantation: An early marker of accelerated coronary heart disease
    • 79. Eich D, Thompson JA, Ko DJ, et al. (1991) Hypercholesterolemia in long-term survivors of heart transplantation: an early marker of accelerated coronary heart disease. Journal of Heart and Lung Transplantation, 10, 45-49.
    • (1991) Journal of Heart and Lung Transplantation , vol.10 , pp. 45-49
    • Eich, D.1    Thompson, J.A.2    Ko, D.J.3
  • 80
    • 9344254902 scopus 로고    scopus 로고
    • The effect of pravastatin on acute rejection after kidney transplantation - A pilot study
    • 80. Katznelson S, Wilkinson AH, Kobashigawa JA, et al. (1996) The effect of pravastatin on acute rejection after kidney transplantation - a pilot study. Transplantation, 61, 1469-1474.
    • (1996) Transplantation , vol.61 , pp. 1469-1474
    • Katznelson, S.1    Wilkinson, A.H.2    Kobashigawa, J.A.3
  • 81
    • 0030691990 scopus 로고    scopus 로고
    • Effect of simvastatin on cyclosporine unbound fraction and apparent blood clearance in heart transplant recipients
    • 81. Akhlaghi F, McLachlan AJ, Keogh AM, Brown KF. (1997) Effect of simvastatin on cyclosporine unbound fraction and apparent blood clearance in heart transplant recipients. British Journal of Clinical Pharmacology, 44, 537-542.
    • (1997) British Journal of Clinical Pharmacology , vol.44 , pp. 537-542
    • Akhlaghi, F.1    McLachlan, A.J.2    Keogh, A.M.3    Brown, K.F.4
  • 83
    • 0030802435 scopus 로고    scopus 로고
    • Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials
    • 83. Hebert PR, Gaziano JM, Chan KS, Hennekens C.H. (1997) Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials. Journal of the American Medical Association, 278, 313-321.
    • (1997) Journal of the American Medical Association , vol.278 , pp. 313-321
    • Hebert, P.R.1    Gaziano, J.M.2    Chan, K.S.3    Hennekens, C.H.4
  • 84
    • 0031969035 scopus 로고    scopus 로고
    • The inhibitory effects of pravastatin on natural killer cell activity in vivo and on cytotoxic T lymphocyte activity in vitro
    • 84. Katznelson W, Wang XM, Chia D, et al. (1998) The inhibitory effects of pravastatin on natural killer cell activity in vivo and on cytotoxic T lymphocyte activity in vitro. Journal of Heart and Lung Transplantation, 17, 335-240.
    • (1998) Journal of Heart and Lung Transplantation , vol.17 , pp. 335-1240
    • Katznelson, W.1    Wang, X.M.2    Chia, D.3
  • 85
    • 0025200422 scopus 로고
    • Reversal of lovastatin-mediated inhibition of natural killer cell activity
    • 85. Cutts JL, Bankhurst AD. (1990) Reversal of lovastatin-mediated inhibition of natural killer cell activity. Journal of Cell Physiology, 145, 244-252.
    • (1990) Journal of Cell Physiology , vol.145 , pp. 244-252
    • Cutts, J.L.1    Bankhurst, A.D.2
  • 86
    • 0002943815 scopus 로고    scopus 로고
    • Relative decrease of cytotoxic T cells in kidney transplanted patients
    • 86. Rothe G, Elbracht R, Hauser I, et al. (1997) Relative decrease of cytotoxic T cells in kidney transplanted patients [abstract]. Atherosclerosis, 134, 282.
    • (1997) Atherosclerosis , vol.134 , pp. 282
    • Rothe, G.1    Elbracht, R.2    Hauser, I.3
  • 87
    • 0027977857 scopus 로고
    • Low-dose simvastatin is a well tolerated and efficacious cholesterol-lowering agent in ciclosporin-treated kidney transplant recipients, double-blind, randomized, placebo-controlled study in 40 patients
    • 87. Arnadottir M, Eriksson L-O, Germershausen JI, Thysell H. (1994) Low-dose simvastatin is a well tolerated and efficacious cholesterol-lowering agent in ciclosporin-treated kidney transplant recipients, double-blind, randomized, placebo-controlled study in 40 patients. Nephron, 68, 57-62.
    • (1994) Nephron , vol.68 , pp. 57-62
    • Arnadottir, M.1    Eriksson, L.-O.2    Germershausen, J.I.3    Thysell, H.4
  • 88
    • 0032572043 scopus 로고    scopus 로고
    • Antiatherothrombotic properties of statins. Implications for cardiovascular event reduction
    • 88. Rosenson RS, Tangney CC. (1998) Antiatherothrombotic properties of statins. Implications for cardiovascular event reduction. Journal of the American Medical Association, 279, 1643-1650.
    • (1998) Journal of the American Medical Association , vol.279 , pp. 1643-1650
    • Rosenson, R.S.1    Tangney, C.C.2
  • 90
    • 13144294068 scopus 로고    scopus 로고
    • Treatment of hypercholesterolemia with fluvastatin in kidney transplant patients
    • 90. Melchor JL, Gracida C. (1998) Treatment of hypercholesterolemia with fluvastatin in kidney transplant patients. Transplant Proceedings, 30, 2054.
    • (1998) Transplant Proceedings , vol.30 , pp. 2054
    • Melchor, J.L.1    Gracida, C.2


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