Efficacy of a novel metalloprotease inhibitor on botulinum neurotoxin B activity

FEBS Letters

Volumn 429, Issue 3, 1998, Pages 234-238

  Adler, Michael ^a   Nicholson, James D ^b   Hackley Jr , Brennie E ^a  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

^b DAKKRO Corporation   (United States)

Author keywords

Botulinum toxin B; Synaptobrevin 2; Zinc metalloprotease inhibitor

Indexed keywords

7 N PHENYLCARBAMOYLAMINO 4 CHLORO 3 PROPYLOXYISOCOUMARIN; BOTULINUM TOXIN B; COUMARIN DERIVATIVE; METALLOPROTEINASE INHIBITOR; SYNAPTOBREVIN; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; ARTICLE; CATALYSIS; CELL FREE SYSTEM; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; INTERNALIZATION; MOTOR NERVE; NONHUMAN; PRIORITY JOURNAL;

BOTULINUM TOXINS; CAPTOPRIL; COUMARINS; DOSE-RESPONSE RELATIONSHIP, DRUG; METALLOENDOPEPTIDASES; PROTEASE INHIBITORS; SPECTROMETRY, FLUORESCENCE; ZINC;

EID: 0032537562     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)00492-X     Document Type: Article

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