Invasive aspergillosis associated with prolonged leukopenia in a murine model

Journal de Mycologie Medicale

Volumn 9, Issue 4, 1999, Pages 221-225

  Dannaoui, E ^a   Addo, A ^a   Borel, E ^a   Piens, M A ^a   Persat, F ^a   Picot, S ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Animal model; Histopathology; Invasive aspergillosis

Indexed keywords

CYCLOPHOSPHAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLUS FUMIGATUS; COLONY FORMING UNIT; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; INOCULATION; LEUKOPENIA; LUNG ASPERGILLOSIS; MORTALITY; MOUSE; NONHUMAN; VIRULENCE;

EID: 0033391103     PISSN: 11565233     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Denning DW, Stevens DA. Antifungal and surgical treatment of invasive aspergillosis: review of 2,121 published cases. Rev Infect Dis 1990;12:1147-201.
2. Denning DW. Invasive aspergillosis in immunocompromised patients. Curr Opin Infect Dis 1994;7:456-62.
3. Denning DW, Hall L, Jackson M, Hollis S. Efficacy of D0870 compared with those of itraconazole an amphotericin B in two murine models of invasine aspergillosis. Antimicrob Agents Chemother 1995; 39:1809-14.
4. Dixon DM, Polak A, Walsh TJ. Fungus dose-dependent primary pulmonary aspergillosis in immunosuppressed mice. Infect Immun 1989;57:1452-6.
5. Eisenstein DJ, Biddinger PW, Rhodes JC. Experimental murine invasive pulmonary aspergillosis. Am J Clin Pathol 1990;93:510-5.
6. Gerson SL, Talbot GH, Hutwitz S, Strom BL, Lusk EJ, Cassileth PA. Prolonged granulocytopenia: the major risk factor for invasive pulmonary aspergillosis in patients with acute leukemia. Ann Intern Med 1984;100:345-51.
7. Roilides E, Katsifa H, Walsh TJ. Pulmonary host defences against Aspergillus fumigatus. Res Immunol 1998;149:454-65.
8. Saral R. Candida and Aspergillus infections in immunocompromised patients: an overview. Rev Infect Dis 1991;31:487-92.
9. Verweij PE, Oakley KL, Morrissey J, Morrissey G, Denning DW. Efficacy of LY303366 against amphotericin B-susceptible and -resistant Aspergillus fumigatus in a murine model of invasive aspergillosis. Antimicrob Agents Chemother 1998;42:873-8.