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Volumn 168, Issue 4, 1999, Pages 242-245

Non-steroidal anti-inflammatory drugs (NSAIDs) and gastro-intestinal toxicity: Current issues

Author keywords

[No Author keywords available]

Indexed keywords

5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; ACETYLSALICYLIC ACID; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; FLOSULIDE; INDOMETACIN; KETOPROFEN; MELOXICAM; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NAPROXEN; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; PROSTACYCLIN; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROTON PUMP INHIBITOR; STOMACH SECRETION INHIBITOR; SUCRALFATE; SULINDAC;

EID: 0033390634     PISSN: 00211265     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02944348     Document Type: Review
Times cited : (15)

References (42)
  • 1
    • 0016966150 scopus 로고
    • Rheumatoid arthritis: A double-blind comparison with indomethacin and placebo
    • Rheumatoid arthritis: A double-blind comparison with indomethacin and placebo. International Journal of Clinical Pharmacology 1976; 13: 292-7.
    • (1976) International Journal of Clinical Pharmacology , vol.13 , pp. 292-297
  • 2
    • 0026485080 scopus 로고
    • Double-blind trial of aspirin in primary prevention of myocardial infarction in patients with stable chronic angina pectoris
    • Juul-moller, S., Edvardsson, N., Jahnmatz, B.et al. Double-blind trial of aspirin in primary prevention of myocardial infarction in patients with stable chronic angina pectoris. Lancet 1992; 340: 1421-1425.
    • (1992) Lancet , vol.340 , pp. 1421-1425
    • Juul-moller, S.1    Edvardsson, N.2    Jahnmatz, B.3
  • 3
    • 0023805341 scopus 로고
    • Randomised trial of intravenous streptokinase, oral aspirin, both, or neither in 17187 cases of suspected acute myocardial infarction: ISIS-2
    • ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither in 17187 cases of suspected acute myocardial infarction: ISIS-2. Lancet 1988; 2: 349-60.
    • (1988) Lancet , vol.2 , pp. 349-360
  • 4
    • 0026355123 scopus 로고
    • Diclofenac sodium (Valtaren) in UK-TIA Study Group. United Kingdom transient ischaemic attack (UK-TIA) aspirin trial
    • Kirchheiner, B., Trang, L., Wellheim, F. A. Diclofenac sodium (Valtaren) in UK-TIA Study Group. United Kingdom transient ischaemic attack (UK-TIA) aspirin trial. J. Neurol. Neurosurg. Psychiatry 1991; 54: 1044-54.
    • (1991) J. Neurol. Neurosurg. Psychiatry , vol.54 , pp. 1044-1054
    • Kirchheiner, B.1    Trang, L.2    Wellheim, F.A.3
  • 5
    • 0020679929 scopus 로고
    • "AICLA" controlled trial of aspirin and dipyridamole in the secondary prevention of athero-thrombotic cerebral ischemia
    • Bousser, M. G., Eschwege, E., Haguenau, M., Lefauconnier, J. M., Thibult, N., Touboul, D. et al. "AICLA" controlled trial of aspirin and dipyridamole in the secondary prevention of athero-thrombotic cerebral ischemia. Stroke 1983; 14:5-14.
    • (1983) Stroke , vol.14 , pp. 5-14
    • Bousser, M.G.1    Eschwege, E.2    Haguenau, M.3    Lefauconnier, J.M.4    Thibult, N.5    Touboul, D.6
  • 6
    • 0028344925 scopus 로고
    • Aspirin and non-steroidal anti-inflammatory drug use and the risk of subsequent colorectal cancer
    • Peleg, L, Maibach, H. T., Brown, S. H. et al. Aspirin and non-steroidal anti-inflammatory drug use and the risk of subsequent colorectal cancer. Arch. Intern. Med. 1994; 154: 394-399.
    • (1994) Arch. Intern. Med. , vol.154 , pp. 394-399
    • Brown, S.H.1
  • 7
    • 0020565187 scopus 로고
    • Sulindac for polyposis of the colon
    • Waddell, W. R. Loughry, R. W. Sulindac for polyposis of the colon. J. Surg. Oncol. 1983; 24: 83-87.
    • (1983) J. Surg. Oncol. , vol.24 , pp. 83-87
    • Waddell, W.R.1    Loughry, R.W.2
  • 8
    • 0028221862 scopus 로고
    • NSAlDs: Time to re-evaluate gut toxicity
    • Bateman, D. N. NSAlDs: Time to re-evaluate gut toxicity. Lancet 1994; 343: 1051-52.
    • (1994) Lancet , vol.343 , pp. 1051-1052
    • Bateman, D.N.1
  • 9
    • 0022202954 scopus 로고
    • PDS Arthritis Advisory Committee meeting: Post-marketing surveillance of NSAIDs
    • Paulus, H. E. PDS Arthritis Advisory Committee meeting: Post-marketing surveillance of NSAIDs. Arthritis Rheum. 1985; 28: 1168-69.
    • (1985) Arthritis Rheum. , vol.28 , pp. 1168-1169
    • Paulus, H.E.1
  • 10
    • 0022639534 scopus 로고
    • Rising frequency of ulcer perforation in elderly people in United Kingdom
    • Walt, R., Katschinski, B., Logan, R., Ashley, J., Langman, M. Rising frequency of ulcer perforation in elderly people in United Kingdom. Lancet 1986; 1: 489-92.
    • (1986) Lancet , vol.1 , pp. 489-492
    • Walt, R.1    Katschinski, B.2    Logan, R.3    Ashley, J.4    Langman, M.5
  • 11
  • 12
    • 0023238811 scopus 로고
    • Blood and protein loss via small intestinal inflammation induced by non steroidal anti-inflammatory drugs
    • Bjarnason, I., Zanelli, G., Prowse, P. et al. Blood and protein loss via small intestinal inflammation induced by non steroidal anti-inflammatory drugs. Lancet 1987; 2: 711-714.
    • (1987) Lancet , vol.2 , pp. 711-714
    • Bjarnason, I.1    Zanelli, G.2    Prowse, P.3
  • 15
    • 0028929443 scopus 로고
    • Prophylactic Aspirin and the risk of peptic ulcer bleeding
    • Weil, J., Colin-Jones, D., Langman, M. J. S. et al. Prophylactic Aspirin and the risk of peptic ulcer bleeding. BMJ 1995; 310:827-30.
    • (1995) BMJ , vol.310 , pp. 827-830
    • Weil, J.1    Colin-Jones, D.2    Langman, M.J.S.3
  • 16
    • 0028327671 scopus 로고
    • Risk of upper gastrointestinal bleeding and perforation associated with individual NSAIDs
    • Rodriguez, L. A. G., Jick, H. Risk of upper gastrointestinal bleeding and perforation associated with individual NSAIDs. Lancet 1994; 343: 769-72.
    • (1994) Lancet , vol.343 , pp. 769-772
    • Rodriguez, L.A.G.1    Jick, H.2
  • 18
    • 0029015290 scopus 로고
    • New insights into prostaglandins and mucosal defence
    • Wallace, J. L., Tigley, A. W. New insights into prostaglandins and mucosal defence. Aliment. Pharmacol. Ther. 1995; 9: 227-235.
    • (1995) Aliment. Pharmacol. Ther. , vol.9 , pp. 227-235
    • Wallace, J.L.1    Tigley, A.W.2
  • 20
    • 0022355668 scopus 로고
    • Effect of indomethacin, tiaprofenic acid diclofenac on rat gastric mucosal damage and content of prostacyclin and prostaglandin E2
    • Kobayashi, K., Arakawa, T., Satoh, H., Fukuda, T., Nakamura, H. Effect of indomethacin, tiaprofenic acid diclofenac on rat gastric mucosal damage and content of prostacyclin and prostaglandin E2. Prostaglandins 1985; 30:609-18.
    • (1985) Prostaglandins , vol.30 , pp. 609-618
    • Kobayashi, K.1    Arakawa, T.2    Satoh, H.3    Fukuda, T.4    Nakamura, H.5
  • 21
    • 0023031844 scopus 로고
    • Effect of acetylsalicylic acid on gastric mucin viscosity, permeability to hydrogen ions, and susceptibility to pepsin
    • Saroseik, J., Mizuta, K., Slomiany, A. et al. Effect of acetylsalicylic acid on gastric mucin viscosity, permeability to hydrogen ions, and susceptibility to pepsin. Biochem. Pharmacol. 1986; 35: 4291-95.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 4291-4295
    • Saroseik, J.1    Mizuta, K.2    Slomiany, A.3
  • 22
    • 0343311821 scopus 로고
    • Mechanism of chemotactic factor stimulation of polymorphonuclear leukocytes: Modulation by prostaglandins
    • Higgs, G. A., Williams, T. J., eds. London: MacMillan
    • Fantone, J. C. Mechanism of chemotactic factor stimulation of polymorphonuclear leukocytes: modulation by prostaglandins. In: Higgs, G. A., Williams, T. J., eds. Inflammatory mediators. London: MacMillan 1985: 127-48.
    • (1985) Inflammatory Mediators , pp. 127-148
    • Fantone, J.C.1
  • 23
    • 0021690166 scopus 로고
    • Effect on indomethacin on gastric acid and bicarbonate secretions in humans
    • Feldman, M., Colturi, T. J. Effect on indomethacin on gastric acid and bicarbonate secretions in humans. Gastroenterology 1984; 87: 1339-43.
    • (1984) Gastroenterology , vol.87 , pp. 1339-1343
    • Feldman, M.1    Colturi, T.J.2
  • 24
    • 0023135384 scopus 로고
    • Indomethacin inhibits duodenal mucosal bicarbonate secretion and endogenous prostaglandin E2 output in human subjects
    • Selling, J. A., Hogan, D. L., Aly, A. et al. Indomethacin inhibits duodenal mucosal bicarbonate secretion and endogenous prostaglandin E2 output in human subjects. Ann. Intern. Med. 1987; 106: 368-71.
    • (1987) Ann. Intern. Med. , vol.106 , pp. 368-371
    • Selling, J.A.1    Hogan, D.L.2    Aly, A.3
  • 26
    • 0026588961 scopus 로고
    • Mitogeninducible prostaglandin G/H synthase: A new target for NSAIDs
    • Xie, W., Robertson, D. L., Simmons, D. L. Mitogeninducible prostaglandin G/H synthase: a new target for NSAIDs. Drug Dev. Res. 1992; 25: 249-65.
    • (1992) Drug Dev. Res. , vol.25 , pp. 249-265
    • Xie, W.1    Robertson, D.L.2    Simmons, D.L.3
  • 27
    • 0027944075 scopus 로고
    • Pharmacological and biochemical demonstration of the role of cyclo-oxygenase 2 in inflammation and pain
    • Seibert, K., Zhang, Y., Leahy, K., Hauser, S. et al. Pharmacological and biochemical demonstration of the role of cyclo-oxygenase 2 in inflammation and pain. Proc. Natl. Acad. Sci. USA. 1994; 91: 12013-10217.
    • (1994) Proc. Natl. Acad. Sci. USA. , vol.91 , pp. 12013-110217
    • Seibert, K.1    Zhang, Y.2    Leahy, K.3    Hauser, S.4
  • 28
    • 0028323295 scopus 로고
    • Inducible isoforms of cyclooxygenase and nitric oxide synthase in inflammation
    • Vane, J. R., Mitchell, J. A., Appleton, I., Willoughby, D. A. et al. Inducible isoforms of cyclooxygenase and nitric oxide synthase in inflammation. Proc. Natl. Acad Sci. USA. 1994; 91:2046-2050.
    • (1994) Proc. Natl. Acad Sci. USA. , vol.91 , pp. 2046-2050
    • Vane, J.R.1    Mitchell, J.A.2    Appleton, I.3    Willoughby, D.A.4
  • 29
    • 0028322893 scopus 로고
    • Selective inhibition of inducible cyclo-oxygenase 2 in vivo is anti-inflammatory and non ulcerogenic
    • Masferrer, J. L., Zweifel, B. S., Manning, P. T. et al. Selective inhibition of inducible cyclo-oxygenase 2 in vivo is anti-inflammatory and non ulcerogenic. Proc. Natl. Acad. Sci. USA. 1994; 91: 3228-3232.
    • (1994) Proc. Natl. Acad. Sci. USA. , vol.91 , pp. 3228-3232
    • Masferrer, J.L.1    Zweifel, B.S.2    Manning, P.T.3
  • 31
    • 0029088821 scopus 로고
    • Etodolac selectively inhibits human PGHS-1 versus PGHS2
    • Glaser, K., Sung, M. L., O'Neill, K., Belfast, M. et al. Etodolac selectively inhibits human PGHS-1 versus PGHS2. Eur. J. Phamacol. 1995; 281: 107-111.
    • (1995) Eur. J. Phamacol. , vol.281 , pp. 107-111
    • Glaser, K.1    Sung, M.L.2    O'Neill, K.3    Belfast, M.4
  • 32
    • 0028818478 scopus 로고
    • Randomized double blind comparison of placebo etodolac, and naproxen on gastrointestinal injury and psotaglandin production
    • Laine, L., Sloane, R., Ferretti, M., Cominelli, F. A randomized double blind comparison of placebo etodolac, and naproxen on gastrointestinal injury and psotaglandin production; Gastrointestinal Endoscopy. 1995; 42:428-33.
    • (1995) Gastrointestinal Endoscopy. , vol.42 , pp. 428-433
    • Laine, L.1    Sloane, R.2    Ferretti, M.3    Cominelli, F.A.4
  • 34
    • 0027359478 scopus 로고
    • Gastric tolerability of nimesulide. a double-blind comparison of two dosage regimens and placebo
    • Marini, U., Spotti, D. Gastric tolerability of nimesulide. A double-blind comparison of two dosage regimens and placebo. Drugs 1993; 46S: 249-52
    • (1993) Drugs , vol.46 , pp. 249-252
    • Marini, U.1    Spotti, D.2
  • 35
    • 0343747486 scopus 로고    scopus 로고
    • Nimesulide, a selective COX-2 inhibitor, cause less gastro-intestinal damage compared with naproxen: A prospective study in human volunteers
    • Shah, A. A., Murray, F. E., Thjodleifsson, B., Oddsson, E., Gudjonsson, H., Sigthorsson, G., Bjarason, I., Fitzgerald, D. J. Nimesulide, a selective COX-2 inhibitor, cause less gastro-intestinal damage compared with naproxen: A prospective study in human volunteers. Gut 1998; 42 (Suppl. 1);A68.
    • (1998) Gut , vol.42 , Issue.1 SUPPL.
    • Shah, A.A.1    Murray, F.E.2    Thjodleifsson, B.3    Oddsson, E.4    Gudjonsson, H.5    Sigthorsson, G.6    Bjarason, I.7    Fitzgerald, D.J.8
  • 36
    • 0031016921 scopus 로고    scopus 로고
    • A randomized, double-blind, cross over, competitive endoscopy study on the gastro-intestinal tolerability of a highly specific COX-2 inhibitor flosulide ,-, and naproxen
    • Bjarason, I., MacPherson, A., Rotman, H., Schupp, J., Hayllar, J. A randomized, double-blind, cross over, competitive endoscopy study on the gastro-intestinal tolerability of a highly specific COX-2 inhibitor flosulide ,-, and naproxen. Scand. J. Gastroenterol. 1997; 32: 126-30.
    • (1997) Scand. J. Gastroenterol. , vol.32 , pp. 126-130
    • Bjarason, I.1    MacPherson, A.2    Rotman, H.3    Schupp, J.4    Hayllar, J.5
  • 37
    • 0027244454 scopus 로고
    • Side effects of NSAIDs on the small and large intestine in humans
    • Bjarnason, I., Hayllar, J., MacPherson, Russell A. S. Side effects of NSAIDs on the small and large intestine in humans. Gastroenterology 1993; 104: 1832-47.
    • (1993) Gastroenterology , vol.104 , pp. 1832-1847
    • Bjarnason, I.1    Hayllar, J.2    Russell, A.S.3
  • 38
    • 0029918291 scopus 로고    scopus 로고
    • Feacal calprotectin shedding after short term treatment with NSAIDs
    • Meling.T. R.,Aabakken, L.,Roseth, A., Osnes, M. Feacal calprotectin shedding after short term treatment with NSAIDs. Scand. J. Gastroenterol. 1996; 31: 339-344.
    • (1996) Scand. J. Gastroenterol. , vol.31 , pp. 339-344
    • Meling.t, R.1    Osnes, M.2
  • 39
    • 0027482294 scopus 로고
    • Nimesulide in the treatment of osteoarthritis. Double blind studies in comparison with piroxicam, ketoprofen and placebo
    • Dreiser, R. L., Riebenfeld, D. Nimesulide in the treatment of osteoarthritis. Double blind studies in comparison with piroxicam, ketoprofen and placebo. Drug 1993; 46 (SuppI 1): 191-195.
    • (1993) Drug , vol.46 , pp. 191-195
    • Dreiser, R.L.1    Riebenfeld, D.2
  • 40
    • 0024409166 scopus 로고
    • Efficacy and tolerability of nimesulide in elderly patients with osteoarthritis: Double blind trial versus naproxen
    • Fossaluzza, V., Montagnani, G. Efficacy and tolerability of nimesulide in elderly patients with osteoarthritis: double blind trial versus naproxen. J. Int. Med. Res. 1989; 17:295303.
    • (1989) J. Int. Med. Res. , vol.17 , pp. 295303
    • Fossaluzza, V.1    Montagnani, G.2
  • 41
    • 0027082657 scopus 로고
    • Post marketing surveillance on nimesulide in the treatment of 8354 patients over 60 years old affected with acute and chronic musculoskeletal diseases
    • Mêle, G., Memeo, A., Mellisi, L. et al. Post marketing surveillance on nimesulide in the treatment of 8354 patients over 60 years old affected with acute and chronic musculoskeletal diseases. Arch Med. Interna, (in Italian). 1992; 44: 213-21.
    • (1992) Arch Med. Interna, (In Italian). , vol.44 , pp. 213-221
    • Mêle, G.1    Memeo, A.2    Mellisi, L.3
  • 42
    • 0025873243 scopus 로고
    • Post marketing survey of nimesulide in the short term treatment of osteoarthritis
    • Pochobradsky, M. G., Mêle, G. Bretta, A. Post marketing survey of nimesulide in the short term treatment of osteoarthritis. Drug Exper. Clin. Res. 1991; 17: 197-204.
    • (1991) Drug Exper. Clin. Res. , vol.17 , pp. 197-204
    • Pochobradsky, M.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.