메뉴 건너뛰기




Volumn 32, Issue 2, 1997, Pages 126-130

A randomized, double-blind, crossover comparative endoscopy study on the gastroduodenal tolerability of a highly specific cyclooxygenase-2 inhibitor, flosulide, and naproxen

Author keywords

Cyclooxygenase inhibition; Drug toxicity; Nonsteroidal anti inflammatory drugs

Indexed keywords

FLOSULIDE; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; PROSTAGLANDIN SYNTHASE INHIBITOR;

EID: 0031016921     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.3109/00365529709000182     Document Type: Article
Times cited : (52)

References (38)
  • 1
    • 0024338076 scopus 로고
    • Current controversies in rheumatology. Controversies and management of non-steroidal anti-inflammatory drug induced side effects on upper gastrointestinal tract
    • Barrier CH, Hirschowitz BI. Current controversies in rheumatology. Controversies and management of non-steroidal anti-inflammatory drug induced side effects on upper gastrointestinal tract. Arthritis Rheum 1989;32:926-9.
    • (1989) Arthritis Rheum , vol.32 , pp. 926-929
    • Barrier, C.H.1    Hirschowitz, B.I.2
  • 2
    • 0023217399 scopus 로고
    • Nonsteroidal anti-inflammatory drugs and life threatening complications of peptic ulcer disease
    • Armstrong CP, Blower AL. Nonsteroidal anti-inflammatory drugs and life threatening complications of peptic ulcer disease. Gut 1987;28:527-32.
    • (1987) Gut , vol.28 , pp. 527-532
    • Armstrong, C.P.1    Blower, A.L.2
  • 3
    • 0027244454 scopus 로고
    • Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine
    • Bjarnason I, Hayllar J, Macpherson AJ, Russell AS. Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine. Gastroenterology 1993;104:1832-47.
    • (1993) Gastroenterology , vol.104 , pp. 1832-1847
    • Bjarnason, I.1    Hayllar, J.2    Macpherson, A.J.3    Russell, A.S.4
  • 5
    • 0026674556 scopus 로고
    • Non-steroidal anti-inflammatory drug gastropathy and cytoprotection: Pathogenesis and mechanisms re-examined
    • Wallace JL. Non-steroidal anti-inflammatory drug gastropathy and cytoprotection: pathogenesis and mechanisms re-examined. Scand J Gastroenterol 1992;27 Suppl 192:3-8.
    • (1992) Scand J Gastroenterol , vol.27 , Issue.192 SUPPL. , pp. 3-8
    • Wallace, J.L.1
  • 6
    • 0026544632 scopus 로고
    • Pathogenesis of NSAID gastropathy: Are neutrophils the culprits?
    • Wallace JL, Granger DN. Pathogenesis of NSAID gastropathy: are neutrophils the culprits? Trends Pharmacol Sci 1992;13:129-30.
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 129-130
    • Wallace, J.L.1    Granger, D.N.2
  • 7
    • 0013637586 scopus 로고
    • Protective mechanisms of the gastric mucosa
    • Gustsavsson S, Kumar D, Graham DY, editors. Edinburgh: Churchill Livingstone
    • Whittle BJR. Protective mechanisms of the gastric mucosa. In: Gustsavsson S, Kumar D, Graham DY, editors. The stomach. Edinburgh: Churchill Livingstone, 1992:81-101.
    • (1992) The Stomach , pp. 81-101
    • Whittle, B.J.R.1
  • 8
    • 0024306005 scopus 로고
    • Mechanisms of gastrointestinal toxicity of nonsteroidal anti- inflammatory drugs
    • Rainsford KD. Mechanisms of gastrointestinal toxicity of nonsteroidal anti- inflammatory drugs. Scand J Gastroenterol 1989; 24 Suppl 163:9-16.
    • (1989) Scand J Gastroenterol , vol.24 , Issue.163 SUPPL. , pp. 9-16
    • Rainsford, K.D.1
  • 9
    • 0026514777 scopus 로고
    • Gastroprotection and nonsteroidal anti-inflammatory drugs
    • Hayllar J, Macpherson A, Bjarnason I. Gastroprotection and nonsteroidal anti-inflammatory drugs. Drug Safety 1992;7:86-105.
    • (1992) Drug Safety , vol.7 , pp. 86-105
    • Hayllar, J.1    Macpherson, A.2    Bjarnason, I.3
  • 10
    • 0028121378 scopus 로고
    • Controversies in NSAID-induced gastroduodenal damage - Do they matter?
    • Fern GC. Controversies in NSAID-induced gastroduodenal damage - do they matter? Aliment Pharmacol Ther 1994;8:15-26.
    • (1994) Aliment Pharmacol Ther , vol.8 , pp. 15-26
    • Fern, G.C.1
  • 12
    • 0028182409 scopus 로고
    • Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in rat
    • Wallace JL, Reuter B, Cicala C, McKnight W, Grisham MB, Cirino G. Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in rat. Gastroenterology 1994;107:173-9.
    • (1994) Gastroenterology , vol.107 , pp. 173-179
    • Wallace, J.L.1    Reuter, B.2    Cicala, C.3    McKnight, W.4    Grisham, M.B.5    Cirino, G.6
  • 14
    • 0026969305 scopus 로고
    • TIS10. A mitogen-inducible glucocorticoid- inhibited gene that encodes a second prostaglandin synthase/cyclooxygenase enzyme
    • Herschman H, Fletcher B, Kujubu D. TIS10. A mitogen-inducible glucocorticoid- inhibited gene that encodes a second prostaglandin synthase/cyclooxygenase enzyme. J Lipid Med 1993;6:89-99.
    • (1993) J Lipid Med , vol.6 , pp. 89-99
    • Herschman, H.1    Fletcher, B.2    Kujubu, D.3
  • 15
    • 0027146692 scopus 로고
    • Selectivity of nonsteroidal anti-inflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
    • Mitchcll JA, Akarasereenout P, Thiemermann C, Flower RJ, Vane JR. Selectivity of nonsteroidal anti-inflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 1993;90:11693-7.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11693-11697
    • Mitchcll, J.A.1    Akarasereenout, P.2    Thiemermann, C.3    Flower, R.J.4    Vane, J.R.5
  • 16
    • 0027293391 scopus 로고
    • Expression of mRNA for cyclooxygenase-1 and cycloozygenase-2 in human tissues
    • O'Neill GP, Ford-Hutchinson AW. Expression of mRNA for cyclooxygenase-1 and cycloozygenase-2 in human tissues. FEBS 1993;330:156-60.
    • (1993) FEBS , vol.330 , pp. 156-160
    • O'Neill, G.P.1    Ford-Hutchinson, A.W.2
  • 18
    • 0025365504 scopus 로고
    • Cyclooxygenase is an immediate-early gene induced by interleukin 1 in human endothelial cell
    • Maier JA, Hla T, Maciag T. Cyclooxygenase is an immediate-early gene induced by interleukin 1 in human endothelial cell. J Biol Chem 1992;265:10805-8.
    • (1992) J Biol Chem , vol.265 , pp. 10805-10808
    • Maier, J.A.1    Hla, T.2    Maciag, T.3
  • 19
    • 0027076645 scopus 로고
    • Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide
    • Lee SH, Soyoola E, Chanmugam P, Hart S, Sun W, Zhong, H et al. Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide. J Biol Chem 1992;267;25934-8.
    • (1992) J Biol Chem , vol.267 , pp. 25934-25938
    • Lee, S.H.1    Soyoola, E.2    Chanmugam, P.3    Hart, S.4    Sun, W.5    Zhong, H.6
  • 20
    • 0028044609 scopus 로고
    • Towards a better aspirin
    • Vane JR. Towards a better aspirin. Nature 1994;367:215-6.
    • (1994) Nature , vol.367 , pp. 215-216
    • Vane, J.R.1
  • 21
    • 0029145880 scopus 로고
    • NSAIDs, Cox-2 inhibitors, and the gut
    • Hayllar J, Bjarnason I. NSAIDs, Cox-2 inhibitors, and the gut. Lancet 1995;346:521-2.
    • (1995) Lancet , vol.346 , pp. 521-522
    • Hayllar, J.1    Bjarnason, I.2
  • 22
    • 0003111607 scopus 로고    scopus 로고
    • Overview-mechanisms of action of anti-inflammatory drugs
    • Vane JR, Botting J, Botting R, editors. Dordrecht: Kluwer Academic Publishers
    • Vane JR, Botting RM. Overview-mechanisms of action of anti-inflammatory drugs. In: Vane JR, Botting J, Botting R, editors. Improved non-steroid anti-inflammatory drugs. Cox-2 enzyme inhibitors. Dordrecht: Kluwer Academic Publishers 1996:1-27.
    • (1996) Improved Non-steroid Anti-inflammatory Drugs. Cox-2 Enzyme Inhibitors , pp. 1-27
    • Vane, J.R.1    Botting, R.M.2
  • 23
    • 0027480087 scopus 로고
    • Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs
    • Meade EA, Smith WL, DeWitt DL. Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs. J Biol Chem 1995;68:6610-4.
    • (1995) J Biol Chem , vol.68 , pp. 6610-6614
    • Meade, E.A.1    Smith, W.L.2    DeWitt, D.L.3
  • 24
    • 0029650018 scopus 로고
    • NSAIDs, Cox-2 inhibitors, and the gut
    • Vane JR. NSAIDs, Cox-2 inhibitors, and the gut. Lancet 1995;346:1105-6.
    • (1995) Lancet , vol.346 , pp. 1105-1106
    • Vane, J.R.1
  • 25
  • 26
    • 0024569690 scopus 로고
    • The pharmacologic profile of CGP 28238, a highly potent anti-inflammatory compound
    • Wiesenberg-Boeettcher I, Schweizer A, Muller K. The pharmacologic profile of CGP 28238, a highly potent anti-inflammatory compound. Agents Actions 1989;26:240-2.
    • (1989) Agents Actions , vol.26 , pp. 240-242
    • Wiesenberg-Boeettcher, I.1    Schweizer, A.2    Muller, K.3
  • 28
    • 0021225004 scopus 로고
    • Endoscopic studies of gastric and duodenal injury after the use of ibuprofen, aspirin, and other nonsteroidal anti-inflammatory agents
    • Lanza FL. Endoscopic studies of gastric and duodenal injury after the use of ibuprofen, aspirin, and other nonsteroidal anti-inflammatory agents. Am J Med 1984;77 Suppl 1 A: 19-24.
    • (1984) Am J Med , vol.77 , Issue.SUPPL. 1A , pp. 19-24
    • Lanza, F.L.1
  • 29
    • 0025666838 scopus 로고
    • Endoscopic evaluation of cimethidine and sucralfate for prevention of naproxen-induced gastroduodenal injury: Effects of scoring method
    • Lanza FL, Graham DY, Davis RE, Rack MF. Endoscopic evaluation of cimethidine and sucralfate for prevention of naproxen-induced gastroduodenal injury: effects of scoring method. Dig Dis Sci 1990;35:1494-9.
    • (1990) Dig Dis Sci , vol.35 , pp. 1494-1499
    • Lanza, F.L.1    Graham, D.Y.2    Davis, R.E.3    Rack, M.F.4
  • 32
    • 0027359491 scopus 로고
    • The prevention and healing of acute NSAID-associated gastroduodenal mucosal damage by misoprostol
    • Bardhan KD, Bjarnason I, Scott DL, Griffin WM, Fenn GC, Shield MJ, et al. The prevention and healing of acute NSAID-associated gastroduodenal mucosal damage by misoprostol. Br J Rheumatol 1993;32:990-5.
    • (1993) Br J Rheumatol , vol.32 , pp. 990-995
    • Bardhan, K.D.1    Bjarnason, I.2    Scott, D.L.3    Griffin, W.M.4    Fenn, G.C.5    Shield, M.J.6
  • 33
    • 0024345169 scopus 로고
    • Epidemiology of NSAID-related gastrointestinal side effects
    • Giercksky KE, Huseby G, Rugstad HE. Epidemiology of NSAID-related gastrointestinal side effects. Scand J Gastroenterol 1989;24 Suppl 163:3-8.
    • (1989) Scand J Gastroenterol , vol.24 , Issue.163 SUPPL. , pp. 3-8
    • Giercksky, K.E.1    Huseby, G.2    Rugstad, H.E.3
  • 34
    • 0028327671 scopus 로고
    • Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs
    • Rodrigues LAG, Jick H. Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs. Lancet 1994;343:769-72.
    • (1994) Lancet , vol.343 , pp. 769-772
    • Rodrigues, L.A.G.1    Jick, H.2
  • 35
    • 0028353941 scopus 로고
    • Risk of bleeding peptic ulcers associated with individual non-steroidal anti-inflammatory drugs
    • Langman MJS, Weil J, Wainwright P, Lawson DH, Rawlins MD, Logan RFA, et al. Risk of bleeding peptic ulcers associated with individual non-steroidal anti-inflammatory drugs. Lancet 1994;343:1075-8.
    • (1994) Lancet , vol.343 , pp. 1075-1078
    • Langman, M.J.S.1    Weil, J.2    Wainwright, P.3    Lawson, D.H.4    Rawlins, M.D.5    Logan, R.F.A.6
  • 36
    • 0023262595 scopus 로고
    • An endoscopic comparison of the effects of etodolac, indomethacin, ibuprofen, naproxen and placebo on the gastrointestinal mucosa
    • Lanza FL, Rack MF, Lynn M, Wolf BS, Sanda M. An endoscopic comparison of the effects of etodolac, indomethacin, ibuprofen, naproxen and placebo on the gastrointestinal mucosa. J Rheumatol 1987;14:338-41.
    • (1987) J Rheumatol , vol.14 , pp. 338-341
    • Lanza, F.L.1    Rack, M.F.2    Lynn, M.3    Wolf, B.S.4    Sanda, M.5
  • 37
    • 0021912785 scopus 로고
    • Gastroscopic findings after treatment with enteric coated and plain naproxen tablets in healthy subjects
    • Trondstad RI, Aadland E, Holler T, Olaussen B. Gastroscopic findings after treatment with enteric coated and plain naproxen tablets in healthy subjects. Scand J Gastroenterol 1985;20:239-42.
    • (1985) Scand J Gastroenterol , vol.20 , pp. 239-242
    • Trondstad, R.I.1    Aadland, E.2    Holler, T.3    Olaussen, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.