Rhodium-105 tetrathioether complexes: Radiochemistry and initial biological evaluation

Nuclear Medicine and Biology

Volumn 26, Issue 8, 1999, Pages 951-957

  Goswami, Niranjan ^a   Higginbotham, Chrys ^b   Volkert, Wynn ^b   Alberto, Roger ^c   Nef, Walter ^c   Jurisson, Silvia ^a  

^a UNIVERSITY OF MISSOURI   (United States)

^b University of Missouri   (United States)

^c PAUL SCHERRER INSTITUTE   (Switzerland)

Author keywords

Acyclic tetrathioethers; Rh(III) tetrathioether complexes; Rhodium 105; Therapeutic radiopharmaceuticals

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; ETHER DERIVATIVE; RHODIUM COMPLEX;

ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG STRUCTURE; MOUSE; NONHUMAN; RADIOBIOLOGY; RADIOCHEMISTRY; SYNTHESIS;

ANIMALS; HYDROGEN-ION CONCENTRATION; INDICATORS AND REAGENTS; ISOTOPE LABELING; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; ORGANOMETALLIC COMPOUNDS; RADIOISOTOPES; RADIOPHARMACEUTICALS; RHODIUM; SULFIDES; TISSUE DISTRIBUTION;

EID: 0033388386     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(99)00070-0     Document Type: Article

References (14)

1. Eckelman W.C. Radiolabeling with Tc-99m to study high capacity and low capacity biochemical systems. Eur. J. Nucl. Med. 22:1995;249-263.
2. Goswami N., Alberto R., Barnes C.L., Jurisson S. Rhodium(III) complexes with acyclic tetrathioether ligands. Effects of backbone chain length on the conformation of the Rh(III) complex. Inorg. Chem. 35:1997;7546-7555.
3. 105Rh as a potential radiotherapeutic agent. Appl. Radiat. Isot. 39:1988;257-260.
4. Guillard R. D. and Wilkinson G. (1964) Complexes of rhodium(III) with chlorine and pyridine. J. Chem. Soc. 1224-1228.
5. Jurisson S.S., Ketring A.R., Volkert W.A. Rhodium-105 complexes as potential radiotherapeutic agents. Transition Met. Chem. 22:1997;315-317.
6. 4 macrocycles in aqueous solution. Radiochim. Acta. 75:1996;83-95.
7. 105Rh-labeled tetradentate thiamacrocycles in rats. Nucl. Med. Biol. 24:1997;85-92.
8. Lo J. M., Pillai M. R. A., John C. C. and Troutner D. E. (1990) Radiochemical purity evaluation of rhodium-105 complexes by magnesium oxide. Int. J. Radiat. Appl. Instrum., Part A, Appl. Radiat. Isotopes 41, 103-105.
9. Nef W. Ph.D. Thesis, University of Basel, Basel, Switzerland, 1996.
10. Rund J.V., Basolo F., Pearson R.G. Catalysis of substitution reactions of rhodium(III) complexes. The reaction of aquapentachlororodate(III) ion with pyridine. Inorg. Chem. 3:1964;658-661.
11. Schubiger P.A., Alberto R., Smith A. Vehicles, chelators, and radionuclides Choosing the "building blocks" of an effective therapeutic radioimmunoconjugate . Bioconj. Chem. 7:1996;165-179.
12. Schubiger P.A., Hasler P.H. Radionuclides for Therapy. 1986;Hoffman-LaRoche & Co., Ltd, Basel, Switzerland.
13. Venkatesh M., Goswami N., Volkert W.A., Schlemper E.O., Ketring A.R., Barnes C.L., Jurisson S. An Rh-105 complex of tetrathiacyclohexane diol with potential for formulating bifunctional chelates. Nucl. Med. Biol. 23:1996;33-40.
14. Volkert W.A., Goeckeler W.F., Ehrhardt G.J., Ketring A.R. Therapeutic radionuclides Production and decay property considerations . J. Nucl. Med. 32:1991;174-185.