NADPH and heme redox modulate pulmonary artery relaxation and guanylate cyclase activation by NO

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 277, Issue 6 21-6, 1999, Pages

  Gupte, Sachin A ^a   Rupawalla, Tasneem ^a   Phillibert Jr , Donald ^a   Wolin, Michael S ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

NADPH oxidoreductase; Nitric oxide; Pentose phosphate pathway

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; DIPHENYLIODONIUM SALT; EPIANDROSTERONE; FERRICYANIDE; FORSKOLIN; GLUTATHIONE PEROXIDASE; GUANYLATE CYCLASE; HEME; NITRIC OXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL CELL; ARTERY DILATATION; ARTICLE; CATTLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; LUNG; NONHUMAN; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; PULMONARY ARTERY;

EID: 0033387868     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1999.277.6.l1124     Document Type: Article

References (33)

1. Arnold, W. P., C. K. Mittal, S. Katsuki, and F. Murad. Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate. Proc. Natl. Acad. Sci. USA 74: 3203-3207, 1977.
2. Brandwein, H. J., J. A. Lewicki, and F. Murad. Reversible inactivation of guanylate cyclase by mixed disulfide formation. J. Biol. Chem. 256: 2958-2962, 1981.
3. Brunner, F., K. Schmidt, E. B. Nielsen, and B. Mayer. Novel guanyl cyclase inhibitor potently inhibits cyclic GMP accumulation in endothelial cells and relaxation of bovine pulmonary artery. J. Pharmacol. Exp. Ther. 277: 48-53, 1996.
4. Burke, T. M., and M. S. Wolin. Hydrogen peroxide elicits pulmonary arterial relaxation and guanylate cyclase activation. Am. J. Physiol. 252 (Heart Circ. Physiol. 21): H721-H732, 1987.
5. Cherry, P. D., H. A. Omar, K. A. Farrell, J. S. Stuart, and M. S. Wolin. Superoxide anion inhibits cGMP-associated bovine pulmonary arterial relaxation. Am. J. Physiol. 259 (Heart Circ. Physiol. 28): H1056-H1062, 1990.
6. 2-metabolism by catalase. Free Radic. Biol. Med. 7: 485-490, 1989.
7. Crane, F. L., I. L. Sun, M. G. Clark, C. Grebing, and H. Low. Transplasma-membrane redox systems in growth and development. Biochim. Biophys. Acta 811: 233-264, 1985.
8. Craven, P. A., and F. R. DeRubertis. Restoration of the responsiveness of purified guanylate cyclase to nitrosoguanidine, nitric oxide, and related activators by heme and hemoproteins. Evidence for involvement of the paramagnetic nitrosyl-heme complex in enzyme activation. J. Biol. Chem. 253: 8433-8443, 1978.
9. Davidson, C. A., P. M. Kaminski, and M. S. Wolin. Nitric oxide elicits prolonged relaxation of bovine pulmonary arteries via endogenous peroxynitrite generation. Am. J. Physiol. 273 (Lung Cell. Mol. Physiol. 17): L437-L444, 1997.
10. Dierks, E. A., and J. N. Burstyn. The deactivation of soluble guanylate cyclase by redox-active agents. Arch. Biochem. Biophys. 351: 1-7, 1998.
11. Gerzer, R., E. Bohme, F. Hofmann, and G. Schultz. Soluble guanylate cyclase purified from bovine lung contains heme and copper. FEBS Lett. 132: 71-74, 1981.
12. Grossman, S., R. Budinsky, and D. Jollow. Dapsone-induced hemolytic anemia: role of glucose-6-phosphate dehydrogenase in the hemolytic response of rat erythrocytes to N-hydroxydapsone. J. Pharmacol. Exp. Ther. 273: 870-877, 1995.
13. Gupte, S., T. Rupawalla, K. M. Mohazzab-H., and M. S. Wolin. Regulation of NO-elicited pulmonary artery relaxation and guanylate cyclase activation by NADH oxidase and SOD. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1535-H1542, 1999.
14. Harrison, D. G. Cellular and molecular mechanisms of endothelial cell dysfunction. J. Clin. Invest. 100: 2153-2157, 1997.
15. Hultquist, D. E. Methemoglobin reduction system of erythrocytes. In: Methods of Enzymology, edited by S. Fleischer and L. Packer. New York: Academic, 1978, vol. 52, p. 463-475.
16. 2. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H978-H985, 1999.
17. Ignarro, L. J. Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein. Circ. Res. 65: 1-21, 1989.
18. Ignarro, L. J., H. Lippton, J. C. Edwards, W. H. Baricos, A. L. Hyman, P. J. Kadowitz, and C. A. Gruetter. Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates. J. Pharmacol. Exp. Ther. 218: 739-749, 1981.
19. Ignarro, L. J., K. S. Wood, and M. S. Wolin. Regulation of purified soluble guanylate cyclase by porphyrins and metalloporphyrins: a unifying concept. Adv. Cyclic Nucleotide Res. 17: 267-274, 1984.
20. Jones, D. P. Determination of pyridine dinucleotide in cell extracts by high-performance liquid chromatography. J. Chromatogr. 225: 446-449, 1981.
21. Kohler, E., H.-J. Barrach, and D. Neubert. Inhibition of NADP dependent oxidoreductases by the 6-aminonicotinamide. FEBS Lett. 6: 225-228, 1970.
22. Mohazzab-H., K. M., P. M. Kaminski, R. Agarwal, and M. S. Wolin. Potential role of a membrane bound NADH oxidoreductase in nitric oxide release and arterial relaxation to nitroprusside. Circ. Res. 84: 220-228, 1999.
23. Mohazzab-H., K. M., and M. S. Wolin. Sites of superoxide anion production detected by lucigenin in calf pulmonary artery smooth muscle. Am. J. Physiol. 267 (Lung Cell. Mol. Physiol. 11): L815-L822, 1994.
24. Murayama, K., and T. Sugawara. Resolution of 52 ninhydrin-positive compounds with a high-speed amino acid analyzer. J. Chromatogr. 224: 315-321, 1981.
25. Pinder, S., B. J. Clark, and A. L. Greenbaum. The assay of intermediates and enzymes involved in the synthesis of the nicotinamide nucleotide in mammalian tissue. Methods Enzymol. 18: 20-32, 1971.
26. Rabinowitz, J. D., J. F. Vacchino, C. Beeson, and H. M. McConnell. Potentiometric measurement of intracellular redox activity. J. Am. Chem. Soc. 120: 2464-2473, 1998.
27. Rostand, S. G., and J. Work. Effect of 6-aminonicotianide on renin release in isolated rat kidney: possible role of the pentose phosphate pathway. Am. J. Physiol. 249 (Renal Fluid Electrolyte Physiol. 18): F213-F219, 1985.
28. Schrammel, A., S. Behrends, K. Schmidt, D. Koesling, and B. Mayer. Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanyl cyclase. Mol. Pharmacol. 50: 1-5, 1996.
29. Stone, J. R., and M. A. Marletta. Soluble guanylate cyclase from bovine lung: activation with nitric oxide and carbon monoxide and spectral characterization of the ferrous and ferric states. Biochemistry 33: 5636-5640, 1994.
30. Thomas, J. A., B. Poland, and R. Honzatko. Protein sulfhydryls and their role in the antioxidant function of protein S-thiolation. Arch. Biochem. Biophys. 319: 1-9, 1995.
31. Wolin, M. S., T. M. Burke-Wolin, P. M. Kaminski, and K. M. Mohazzab-H. Reactive oxygen species and vascular oxygen sensors. In: Nitric Oxide and Radicals in the Pulmonary Vasculature, edited by E. K. Weir, S. L. Archer, and J. T. Reeves. Armonk, NY: Futura, 1996, p. 245-263.
32. Wolin, M. S., K. S. Wood, and L. J. Ignarro. Guanylate cyclase from bovine lung: a kinetic analysis of the regulation of the purified soluble enzyme by protoporphyrin IX, heme and nitrosylheme. J. Biol. Chem. 257: 13312-13320, 1982.
33. Yu, A. E., S. Hu, T. G. Spiro, and J. N. Burstyn. Raman resonance spectroscopy of soluble guanyl cyclase reveals displacement of distal and proximal heme ligands by NO. J. Am. Chem. Soc. 116: 4117-4118, 1994.