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Volumn 102, Issue 3, 1999, Pages 115-123

Apoptosis, bcl-2 expression and p53 accumulation in myelodysplastic syndrome, myelodysplastic-syndrome-derived acute myelogenous leukemia and de novo acute myelogenous leukemia

Author keywords

Acute myelogenous leukemia; Apoptosis; bcl 2; Bone marrow; Immunohistochemistry; Myelodysplastic syndrome; p53; TUNEL

Indexed keywords

PROTEIN BCL 2; PROTEIN P53;

EID: 0033387759     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000040984     Document Type: Article
Times cited : (52)

References (38)
  • 2
    • 0023888449 scopus 로고
    • Recommendations for a morphologic, immunologic, and cytogenetic (MIC) working classification of the primary and therapy-related myelodysplastic disorders
    • Third MIC Cooperative Study Group: Recommendations for a morphologic, immunologic, and cytogenetic (MIC) working classification of the primary and therapy-related myelodysplastic disorders. Cancer Genet Cytogenet 1988;32: 1-10.
    • (1988) Cancer Genet Cytogenet , vol.32 , pp. 1-10
  • 3
    • 0025645740 scopus 로고
    • Apoptosis is a common histopathological finding in myelodysplasia: The correlate of ineffective haematopoiesis
    • Clark DM, Lampert IA: Apoptosis is a common histopathological finding in myelodysplasia: The correlate of ineffective haematopoiesis. Leuk Lymphoma 1990;2:415-418.
    • (1990) Leuk Lymphoma , vol.2 , pp. 415-418
    • Clark, D.M.1    Lampert, I.A.2
  • 4
    • 0027409958 scopus 로고
    • Hypothesis: Apoptosis may be the mechanism responsible for the premature intramedullary cell death in the myelodysplastic syndrome
    • Yoshida Y: Hypothesis: Apoptosis may be the mechanism responsible for the premature intramedullary cell death in the myelodysplastic syndrome. Leukemia 1993;7:144-146.
    • (1993) Leukemia , vol.7 , pp. 144-146
    • Yoshida, Y.1
  • 6
    • 0025204548 scopus 로고
    • bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D, Nuñez G, Milliman C, Schreiber RD, Korsmeyer SJ: bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990;348:334-336.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nuñez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 7
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M: Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 1991; 352:345-347.
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 11
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493-501.
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 13
    • 0019401161 scopus 로고
    • Monoclonal antibodies specific for simian virus 40 tumor antigens
    • Harlow ED, Crawford LV, Pim DC, Williamson NM: Monoclonal antibodies specific for simian virus 40 tumor antigens. J Virol 1981; 39:861-869.
    • (1981) J Virol , vol.39 , pp. 861-869
    • Harlow, E.D.1    Crawford, L.V.2    Pim, D.C.3    Williamson, N.M.4
  • 14
    • 18344401654 scopus 로고    scopus 로고
    • Morphological changes and apoptosis in bone marrow from patients with myelodysplastic syndromes treated with granulocyte-CSF and erythropoietin
    • Hellström-Lindberg E, Kanter-Lewensohn L, Öst Å: Morphological changes and apoptosis in bone marrow from patients with myelodysplastic syndromes treated with granulocyte-CSF and erythropoietin. Leuk Res 1997;21:415-425.
    • (1997) Leuk Res , vol.21 , pp. 415-425
    • Hellström-Lindberg, E.1    Kanter-Lewensohn, L.2    Öst, Å.3
  • 16
    • 0025932984 scopus 로고
    • Apoptosis: Mechanism and roles in pathology
    • Arends MJ, Wyllie AH: Apoptosis: Mechanism and roles in pathology. Int Rev Exp Pathol 1991;32:223-254.
    • (1991) Int Rev Exp Pathol , vol.32 , pp. 223-254
    • Arends, M.J.1    Wyllie, A.H.2
  • 17
    • 0011123295 scopus 로고
    • Endogenous endonuclease-induced DNA fragmentation: An early event in cell mediated cytolysis
    • Duke RC, Chervenak R, Cohen JJ: Endogenous endonuclease-induced DNA fragmentation: An early event in cell mediated cytolysis. Proc Natl Acad Sci USA 1983;80:6361-6365.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 6361-6365
    • Duke, R.C.1    Chervenak, R.2    Cohen, J.J.3
  • 18
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JFR, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26:239-257.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 19
    • 0027255942 scopus 로고
    • Apoptosis and disease
    • Carson DA, Ribeiro JM: Apoptosis and disease. Lancet 1993;341:1251-1254.
    • (1993) Lancet , vol.341 , pp. 1251-1254
    • Carson, D.A.1    Ribeiro, J.M.2
  • 20
    • 0025835716 scopus 로고
    • Bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death
    • Hockenbery DM, Zutter M, Hickey W, Nahm M. Korsmeyer SJ: Bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc Natl Acad Sci USA 1991;88:6961-6965.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6961-6965
    • Hockenbery, D.M.1    Zutter, M.2    Hickey, W.3    Nahm, M.4    Korsmeyer, S.J.5
  • 21
    • 0032171391 scopus 로고    scopus 로고
    • bcl-2 expression by myeloid precursors in myelodysplastic syndromes: Relation to disease progression
    • Davis RE, Greenberg PL: bcl-2 expression by myeloid precursors in myelodysplastic syndromes: Relation to disease progression. Leuk Res 1998;22:767-777.
    • (1998) Leuk Res , vol.22 , pp. 767-777
    • Davis, R.E.1    Greenberg, P.L.2
  • 22
    • 0028169245 scopus 로고
    • p53 expression in myeloid cells of myelodysplastic syndromes: Association with evolution of overt leukemia
    • Kitagawa M, Yoshida S, Kuwata T, Tanizawa T, Kamiyama R: p53 expression in myeloid cells of myelodysplastic syndromes: Association with evolution of overt leukemia. Am J Pathol 1994;145:338-344.
    • (1994) Am J Pathol , vol.145 , pp. 338-344
    • Kitagawa, M.1    Yoshida, S.2    Kuwata, T.3    Tanizawa, T.4    Kamiyama, R.5
  • 25
    • 0025804270 scopus 로고
    • Mutations of the p53 gene in human acute myelogenous leukemia
    • Slingerland JM, Minden MD, Benchimol S: Mutations of the p53 gene in human acute myelogenous leukemia. Blood 1991;77:1500-1507.
    • (1991) Blood , vol.77 , pp. 1500-1507
    • Slingerland, J.M.1    Minden, M.D.2    Benchimol, S.3
  • 26
    • 0027275593 scopus 로고
    • Mutation in the p53 and RAS family genes are associated with tumor progression of BCR/ABL negative chronic myeloproliferative disorders
    • Gaidano G, Guerrasio A, Serra A, Carozzi F, Rege-Cambrin G, Petroni D, Saglio G: Mutation in the p53 and RAS family genes are associated with tumor progression of BCR/ABL negative chronic myeloproliferative disorders. Leukemia 1993;7:946-953.
    • (1993) Leukemia , vol.7 , pp. 946-953
    • Gaidano, G.1    Guerrasio, A.2    Serra, A.3    Carozzi, F.4    Rege-Cambrin, G.5    Petroni, D.6    Saglio, G.7
  • 27
    • 0026486659 scopus 로고
    • Frequent p53 gene mutations in blast crisis myelogenous leukemia, especially in myeloid crisis harboring loss of a chromosome 17p
    • Nakai H, Misawa S, Toguchida J, Yandell DW, Ishizaki K: Frequent p53 gene mutations in blast crisis myelogenous leukemia, especially in myeloid crisis harboring loss of a chromosome 17p. Cancer Res 1992;52:6588-6593.
    • (1992) Cancer Res , vol.52 , pp. 6588-6593
    • Nakai, H.1    Misawa, S.2    Toguchida, J.3    Yandell, D.W.4    Ishizaki, K.5
  • 29
    • 0027261003 scopus 로고
    • Molecular genetics of pediatric brain stem gliomas. Applicaiton of PCR techniques to small and archival brain tumor specimens
    • Louis DN, Rubio MP, Correa KM, Gusella JF, von Deimling A: Molecular genetics of pediatric brain stem gliomas. Applicaiton of PCR techniques to small and archival brain tumor specimens. J Neuropathol Exp Neurol 1993;52: 507-515.
    • (1993) J Neuropathol Exp Neurol , vol.52 , pp. 507-515
    • Louis, D.N.1    Rubio, M.P.2    Correa, K.M.3    Gusella, J.F.4    Von Deimling, A.5
  • 30
    • 0028937721 scopus 로고
    • Radical disparity in the association of p53 gene alterations with breast cancer survival
    • Shiao YH, Chen VW, Scheer WD, Wu XC, Correa P: Radical disparity in the association of p53 gene alterations with breast cancer survival. Cancer Res 1995;55:1485-1490.
    • (1995) Cancer Res , vol.55 , pp. 1485-1490
    • Shiao, Y.H.1    Chen, V.W.2    Scheer, W.D.3    Wu, X.C.4    Correa, P.5
  • 31
    • 0028951290 scopus 로고
    • High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumors and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions
    • Ahomadegbe JC, Barrois M, Fogel S, Le Bihan ML, Douc-Rasy S, Duvillard P, Armand JP, Riou G: High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumors and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions. Oncogene 1995;10:1217-1227.
    • (1995) Oncogene , vol.10 , pp. 1217-1227
    • Ahomadegbe, J.C.1    Barrois, M.2    Fogel, S.3    Le Bihan, M.L.4    Douc-Rasy, S.5    Duvillard, P.6    Armand, J.P.7    Riou, G.8
  • 36
    • 0026786636 scopus 로고
    • Prognostic significance of p53 overexpression in gastric and colorectal carcinoma
    • Starzynska T, Bromley M, Gosh A, Stern PL: Prognostic significance of p53 overexpression in gastric and colorectal carcinoma. Br J Cancer 1992;66:558-562.
    • (1992) Br J Cancer , vol.66 , pp. 558-562
    • Starzynska, T.1    Bromley, M.2    Gosh, A.3    Stern, P.L.4
  • 37
    • 0026737950 scopus 로고
    • Accumulation of p53 protein correlates with a poor prognosis in human lung cancer
    • Quinlan DC, Davidson AG, Summers CL, Warden HE, Doshi HM: Accumulation of p53 protein correlates with a poor prognosis in human lung cancer. Cancer Res 1992;52:4828-4831.
    • (1992) Cancer Res , vol.52 , pp. 4828-4831
    • Quinlan, D.C.1    Davidson, A.G.2    Summers, C.L.3    Warden, H.E.4    Doshi, H.M.5
  • 38
    • 0028020522 scopus 로고
    • Evidence that p53 and bcl-2 are regulators of a common cell death pathway important for in vivo lymphomagenesis
    • Marin MC, Hsu B, Meyn RE, Donehower LA, el-Naggar AK, McDonnell TJ: Evidence that p53 and bcl-2 are regulators of a common cell death pathway important for in vivo lymphomagenesis. Oncogene 1994;9:3107-3112.
    • (1994) Oncogene , vol.9 , pp. 3107-3112
    • Marin, M.C.1    Hsu, B.2    Meyn, R.E.3    Donehower, L.A.4    El-Naggar, A.K.5    McDonnell, T.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.