In vivo pharmacology and anti-tumour evaluation of the tyrphostin tyrosine kinase inhibitor RG13022

British Journal of Cancer

Volumn 74, Issue 11, 1996, Pages 1714-1718

  McLeod, H L ^a,d   Brunton, V G ^a   Eckardt, N ^a   Lear, M J ^a   Robins, D J ^a   Workman, P ^a,b   Graham, M A ^a,c  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

^c Sanofi Winthrop   (United Kingdom)

^d UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Pharmacokinetics; Tumour xenograft; Tyrosine kinase inhibitor; Tyrphostin

Indexed keywords

2 (3' PYRIDYL) 3 (3,4 DIMETHOXYPHENYL)PROPENONITRILE; ALPHA (3,4 DIMETHOXYBENZYLIDENE) 2 PYRIDYLACETONITRILE; GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE INHIBITOR; TYRPHOSTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DNA SYNTHESIS INHIBITION; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; FEMALE; HUMAN; HUMAN CELL; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TUMOR GROWTH; TUMOR XENOGRAFT;

EID: 0029850505     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.620     Document Type: Article

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