Preparation and local anaesthetic activity of benzotriazinone and benzoyltriazole derivatives

European Journal of Medicinal Chemistry

Volumn 34, Issue 12, 1999, Pages 1043-1051

  Caliendo, Giuseppe ^a   Fiorino, Ferdinando ^a   Grieco, Paolo ^a   Perissutti, Elisa ^a   Santagada, Vincenzo ^a   Meli, Rosaria ^a   Raso, Giuseppina Mattace ^a   Zanesco, Angelina ^b   De Nucci, Gilberto ^b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b Cartesius Analytical Unit   (Brazil)

Author keywords

Benzotriazinone; Benzoyltriazole; Local anaesthetic; Negative chronotropic action

Indexed keywords

BENZOTRIAZINONE DERIVATIVE; BENZOYLTRIAZOLE DERIVATIVE; LIDOCAINE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHRONOTROPISM; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; LOCAL ANESTHESIA; MALE; MOUSE; NERVE BLOCK; NONHUMAN;

EID: 0033379137     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(99)00126-9     Document Type: Article

References (15)

1. Caliendo G., Di Carlo R., Greco G., Grieco P., Meli R., Novellino E., Perissutti E., Santagada V. Eur. J. Med. Chem. 30:1995;603-608.
2. Caliendo G., Greco G., Grieco P., Mattace Raso G., Meli R., Novellino E., Perissutti E., Santagada V. Eur. J. Med. Chem. 31:1996;99-110.
3. Löfgren N. Studies on Local Anaesthetics. 1948;Hoeggstrom, Stockholm.
4. Morgan P.H., Mathison I.W. J. Pharm. Sci. 65:1976;635-648.
5. Heymans L., Le Therizien L., Godfroid J. J. Med. Chem. 23:1980;184-193.
6. Bowden K., Heilbron I.M., Jones E.R.H., Weedon B.C.L. J. Chem. Soc. Part I:1946;39-45.
7. Nesmeyanov A.N., Rybinskaya M.I. Dolk. Akad. Nauk. SSSR. 158:1964;408-410.
8. Biagi G., Ferretti M., Livi O., Scartoni V., Lucacchini A., Mazzoni M. Il Farmaco Ed. Sc. 41:1986;388-400.
9. Livi O., Biagi G., Ferretti M., Lucacchini A., Barili P.L. Eur. J. Med. Chem. -Chim. Ther. 18:1983;471-475.
10. Regnier J. Bull. Sci. Pharm. 30:1923;580-586.
11. Bianchi C. Br. J. Pharmacol. 11:1956;104-106.
12. Tallarida R.J., Murray R.B. Manual of Pharmacological Calculations with Computer Programs. 2nd Edition :1981;Springer, New York.
13. Al Saadi D., Sneider W.E. Arzneim. -Forsch. 41:1991;195-198.
14. Hughes I.E., Smith J.A. J. Pharm. Pharmacol. 30:1978;124-126.
15. Van Rossum J.M. Arch. Int. Pharmacodyn. Ther. 143:1963;299-333.