Synthesis and pharmacological evaluation of a set of N-[2-(alkylamino)ethyl]benzotriazol-X-yl isobutyramides acting as local anesthetics

European Journal of Medicinal Chemistry

Volumn 31, Issue 2, 1996, Pages 99-104

  Caliendo, G ^a   Greco, G ^a   Grieco, P ^a   Mattace Raso, G ^a   Meli, R ^a   Novellino, E ^b   Perissutti, E ^a   Santagada, V ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

Author keywords

Acute toxicity; Benzotriazole; Lipophilicity; Local anesthetic; QSAR

Indexed keywords

BENZOTRIAZOLE DERIVATIVE; LIDOCAINE; LOCAL ANESTHETIC AGENT;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORNEA; DRUG SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; LIPOPHILICITY; LOCAL ANESTHESIA; MALE; MOUSE; NERVE BLOCK; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RABBIT; RAT; SCIATIC NERVE; SUBCUTANEOUS DRUG ADMINISTRATION; TOPICAL DRUG ADMINISTRATION;

EID: 0029998953     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/0223-5234(96)80442-9     Document Type: Article

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