Angiotensin-converting enzyme inhibition prevents loss of glomerular hydraulic permeability in passive Heymann nephritis

Laboratory Investigation

Volumn 79, Issue 12, 1999, Pages 1501-1510

  Remuzzi, Andrea ^a   Monaci, Nives ^a   Bonassi, Maria Enrica ^a   Corna, Daniela ^a   Zoja, Carla ^a   Mohammed, Ehab I ^a   Remuzzi, Giuseppe ^b  

^a MARIO NEGRI INST PHARMACOL RES   (Italy)

^b OSPEDALI RIUNITI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LISINOPRIL;

ANIMAL TISSUE; ARTICLE; CAPILLARY PERMEABILITY; CELL PROLIFERATION; CELL ULTRASTRUCTURE; ENZYME INHIBITION; EPITHELIUM CELL; GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS CAPILLARY; GLOMERULUS FILTRATION; HEYMANN NEPHRITIS; HYDRAULIC PERMEABILITY; IMMUNOHISTOCHEMISTRY; KIDNEY DISEASE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; RAT; WATER LOSS;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; BASEMENT MEMBRANE; CELL MEMBRANE PERMEABILITY; GLOMERULONEPHRITIS; KIDNEY GLOMERULUS; MALE; MICROSCOPY, ELECTRON; PEPTIDYL-DIPEPTIDASE A; RABBITS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0033378256     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Abbate M, Zoja C, Corna D, Capitanio M, Bertani T, and Remuzzi G (1998). In progressive nephropathies, overload of tubular cells with filtered proteins translates glomerular permeability dysfunction into cellular signals of interstitial inflammation. J Am Soc Nephrol 9:1213-1224.
2. Benigni A, ZoJa C, and Remuzzi G (1995). The renal toxicity of sustained glomerular protein traffic. Lab Invest 73:461-468.
3. Couser WG (1998). Pathogenesis of glomerular damage in glomerulonephritis. Nephrol Dial Transplant 13(Suppl 1):10-15.
4. Daniels BS (1993). The role of the glomerular epithelial cell in the maintenance of the glomerular filtration barrier. Am J Nephrol 13:318-323.
5. Daniels BS, Hauser EB, Deen WM, and Hostetter TH (1992). Glomerular basement membrane: In vitro studies of water and protein permeability. Am J Physiol 262:F919-F926.
6. Davison AM, Cameron JS, Kerr DNS, Ogg CS, and Wilkinson RW (1984). The natural history of renal function in untreated idiopathic membranous glomerulonephritis in adults. Clin Nephrol 22:61-67.
7. Donadio JV Jr, Torres VE, Velosa JA, Wagoner RD, Holley KE, Okamura M, Ilstrup DM, and Chu CP (1988). Idiopathic membranous nephropathy: The natural history of untreated patients. Kidney Int 33:708-714.
8. Drumond MC and Deen WM. (1994a). Stokes flow through a row of cylinders between parallel walls: Model for the glomerular slit diaphragm. J Biomech Eng 116:184-189.
9. Drumond MC and Deen WM. (1994b). Structural determinants of glomerular hydraulic permeability. Am J Physiol 266:F1-F12.
10. Drumond MC, Kristal B, Myers BD, and Deen WM. (1994). Structural basis for reduced glomerular filtration capacity in nephrotic humans. J Clin Invest 94:1187-1195.
11. Edgington TS, Glassock RJ, Watson JL, and Dixon FJ (1967). Characterization and isolation of specific renal tubular epithelial antigens. J Immunol 99:1199-1210.
12. Ene-lordache B, Imberti O, Foglieni C, Remuzzi G, Bertani T, and Remuzzi A (1994). Effects of angiotensin-converting enzyme inhibition on glomerular capillary wall ultrastructure in MWF/Ztm rats. J Am Soc Nephrol 5:1378-1384.
13. Fassi A, Sangalli F, Maffi R, Colombi F, Mohamed El, Brenner BM, Remuzzi G, and Remuzzi A (1998). Progressive glomerular injury in the MWF rat is predicted by inborn nephron deficit. J Am Soc Nephrol 9:1399-1406.
14. Feenstra K, van den Lee R, Greben HA, Arends A, and Hoedemaeker PJ (1975). Experimental glomerulonephritis in the rat induced by antibodies directed against tubular antigens. I. The natural history: A histologic and immunohistologic study at the light microscopic and ultrastructural level. Lab Invest 32:235-242.
15. Gloy J, Henger A, Fischer KG, Nitschke R, Bleich M, Mundel P, Schollmeyer P, Greger R, and Pavenstadt H (1998). Angiotensin II modulates cellular functions of podocytes. Kidney Int Suppl 67:168-170.
16. Guasch A and Myers BD (1994). Determinants of glomerular hypofiltration in nephrotic patients with minimal change nephropathy. J Am Soc Nephrol 4:1571-1581.
17. Gundersen HJ, Jensen TB, and Osterby R (1978). Distribution of membrane thickness determined by lineal analysis. J Microsc 113:27-43.
18. Heymann W, Hackel DB, Harwood S, Wilson SGF, and Hunter JLP (1959). Production of nephrotic syndrome in rats by Freund's adjuvants and rat kidney suspensions. Proc Soc Exp Biol Med 100:660-664.
19. Hironaka K, Makino H, Onbe T, Yamasaki Y, Shikata K, Kamata K, and Ota Z (1996). Ultrastructural change of the glomerular basement membrane in rats with Heyman nephritis revealed by ultrahigh resolution scanning electron microscopy. Am J Pathol 179:112-120.
20. Hirose K, Osterby R, Nozawa M, and Gundersen HJG (1982). Development of glomerular lesions in experimental long-term diabetes in the rat. Kidney Int 21:689-695.
21. Kerjaschki D, Miettinen A and Farquhar MG (1987). Initial events in the formation of immune deposits in passive Heymann nephritis. J Exp Med 116:109-128.
22. Lafayette RA, Druzin M, Sibley R, Derby G, Malik T, Huie P, Polhemus C, Deen WM, and Myers BD (1998). Nature of glomerular dysfunction in pre-eclampsia. Kidney Int 54: 1240-1249.
23. Magil AB (1995). Tubulointerstitial lesions in human membranous glomerulonephritis: Relationship to proteinuria. Am J Kidney Dis 25:375-379.
24. Myers BD and Guasch A (1993). Selectivity of the glomerular filtration barrier in healthy and nephrotic humans. Am J Nephrol 13:311-317.
25. Remuzzi A and Mohamed El (1996). Impact of the reninangiotensin system blockade on structure and function of glomerular membrane components in animal models of kidney disease. J Am Soc Nephrol 4(Suppl 1):27-33.
26. Remuzzi G, Ruggenenti P, and Benigni A (1997). Understanding the nature of renal disease progression. Kidney Int 51:2-15.
27. Rodewald R and Karnovsky MJ (1974). Porous substructure of the glomerular slit diaphragm in the rat and mouse. J Cell Biol 60:423-433.
28. Ruggenenti P, Perna A, Benini R, Bertani T, Zoccali C, Maggiore Q, Salvadori M, and Remuzzi G (1999). In chronic nephropathies prolonged ACE inhibition can induce remission: Dynamics of time-dependent changes in GFR. J Am Soc Nephrol 10(5):997-1006.
29. Routsalainen V, Ljungberg P, Wartiovaara J, Lenkkeri U, Kestila M, Jalanko H, Holmberg C, and Tryggvason K (1999). Nephrin is specifically located at the slit diaphragm of glomerular podocytes. Proc Natl Acad Sci U S A 96:7962-7967.
30. Schieppati A, Mosconi L, Perna A, Mecca G, Bertani T, Garattini S, and Remuzzi G (1993). Prognosis of untreated patients with idiopathic membranous nephropathy. N Engl J Med 329:85-89.
31. Squarer A, Lemley KV, Ambalavanan S, Kristal B, Deen WM, Sibley R, Anderson L, and Myers BD (1998). Mechanisms of progressive glomerular injury in membranous nephropathy. J Am Soc Nephrol 9:1389-1398.
32. Tisher CC and Brenner BM (1994). Renal pathology, 2nd ed. Philadelphia: JB Lippincott Company.
33. Wallenstein S, Zucker CL, and Fleiss JL (1980). Some statistical methods useful in circulation research. Circ Res 47:1-9.
34. Weibel ER and Bolender RP (1973). Stereologic techniques for electron microscopic morphometry. In: Hayat MA, editor. Principles and techniques for electron microscopy, vol 3. New York: Van Nostrand Reinhold, 273-296.
35. Yoshioka T, Rennke HG, Salant DJ, Deen WM, and Ichikawa I (1987). Role of abnormally high transmural pressure in the permselectivity defect of glomerular capillary wall: A study in early passive Heymann nephritis. Circ Res 61:531-538.
36. Zoja C, Corna D, Bruzzi I, Foglieni C, Bertani T, Remuzzi G, and Benigni A (1996). Passive Heymann nephritis: Evidence that angiotensin-converting enzyme inhibition reduces proteinuria and retards renal structural injury. Exp Nephrol 4:213-221.
37. Zoja C, Donadelli R, Corna D, Testa D, Facchinetti D, Maffi R, Luzzana E, Colosio V, Bertani T, and Remuzzi G (1997). The renoprotective properties of angiotensin-converting enzyme inhibitors in a chronic model of membranous nephropathy are solely due to the inhibition of angiotensin II: Evidence based on comparative studies with a receptor antagonist. Am J Kidney Dis 29:254-264.