Tissue-specific ontogenic expression of prostaglandin H synthase 2 in the ovine myometrium, endometrium, and placenta during late gestation and at spontaneous term labor

American Journal of Obstetrics and Gynecology

Volumn 181, Issue 6, 1999, Pages 1512-1519

  Wen, Xuan Wu ^b   Xiao, Hong Ma ^b   Nathanielsz, Peter W ^a  

^a Department of Obstetrics Gynecology   (United States)

^b NONE

Author keywords

Endometrium; Myometrium; Placenta; Pregnancy; Prostaglandin H synthase 2; Sheep

Indexed keywords

PROSTAGLANDIN SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ENDOMETRIUM; ENZYME LOCALIZATION; FEMALE; LABOR; MYOMETRIUM; NONHUMAN; ONTOGENY; PLACENTA; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; SHEEP; TISSUE SPECIFICITY; TROPHOBLAST;

EID: 0033377089     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0002-9378(99)70398-4     Document Type: Article

References (25)

1. 1. Deayton JM, Young IR, Hollingworth SA, White A, Crosby SR, Thorburn GD. Effect of late hypothalamo-pituitary disconnection on the development of the HPA axis in the ovine fetus and the initiation of parturition. J Neuroendocrinol 1994;6:25-31.
2. 2. Thorburn GD, Rice GE. Placental PGE2 and the initiation of parturition in sheep. In: Mitchell MD, editor. Eicosanoids in reproduction. Boca Raton (FL): CRC Press; 1990. p. 73-86.
3. 3. Liggins GC, Scroop GC, Haughey KG. Comparison of the effects of prostaglandin E2, prostacyclin and 1-24 adrenocorticotropin on plasma cortisol levels of fetal sheep. J Endocrinol 1982;95:153-62.
4. 4. Hollingworth SA, Deayton JM, Young IR, Thorburn GD. Prostaglandin E2 administered to fetal sheep increases the plasma concentration of ACTH and the proportion of ACTH in low molecular weight forms. Endocrinology 1995;136:1233-40.
5. 5. Young IR, Deayton JM, Hollingworth SA, Thorburn GD. Continuous intrafetal infusion of prostaglandin E2 prematurely activates the hypothalamo-pituitary-adrenal axis and induces parturition in sheep. Endocrinology 1996;37:2424-31.
6. 6. Thorburn GD, Hollingworth SA, Hooper SB. The trigger for parturition in sheep: fetal hypothalamus or placenta? J Dev Physiol 1991;115:71-9.
7. 7. Challis JR, Brooks AN. Maturation and activation of hypothalamic-pituitary-adrenal function in fetal sheep. Endocr Rev 1989;10:182-204.
8. 8. Bennett P, Slater D. COX-2 expression in labor. In: Vane J, Botting J, Botting R, editors. Improved non-steroid anti-inflammatory drugs: COX-2 enzyme inhibitors. Norwell (MA): Kluwer Academic Publications; 1996. p. 1-27.
9. 9. Mitchell MD, Flint AP. Use of meclofenamic acid to investigate the role of prostaglandin biosynthesis during induced parturition in sheep. J Endocrinol 1978;76:101-9.
10. 10. Sellers S, Mitchell MD, Bibby J, Anderson AB, Turnbull AC. Comparison of plasma concentrations of prostaglandin levels in term and preterm labour. Br J Obstet Gynaecol 1981;88:362-6.
11. 11. Mijovic JE, Zakar T, Nairn TK, Olson DM. 1998 Prostaglandin endoperoxide H synthase (PGHS) activity and PGHS-1 and -2 messenger ribonucleic acid abundance in human chorion throughout gestation and with preterm labor. J Clin Endocrinol Metab 83:1358-67.
12. 12. Poyser NL. Parturition and lactation. In: Bakhle YS, editor. Prostaglandins in reproduction. New York: RSP Press; 1981. p. 175-211.
13. 13. Gibb W, Matthews SG, Challis JR. Localization and developmental changes inprostaglandin H synthase (PGHS) and PGHS messenger ribonucleic acid in ovine placenta throughout gestation. Biol Reprod 1996;54:654-9.
14. 14. Rice GE, Payne MJ, Wong MH, Thorburn GD. Immunoreactive prostaglandin G/H synthase content increase in cotyledons during late gestation. Placenta 1992;13:429-37.
15. 15. Rice GE, Freed KA, Aitken MA, Jacobs RA. Gestational- and labour-associated changes in the relative abundance of prostaglandin G/H synthase-1 and -2 mRNA in ovine placenta. J Mol Endocrinol 1995;14:237-45.
16. 16. Wimsatt J, Nathanielsz PW, Sirois J. Induction of prostaglandin endoperoxide synthase isoform-2 in ovine cotyledonary tissues during late gestation. Endocrinology 1993;133:1068-73.
17. 17. Williams CS, DuBois RN. Prostaglandin endoperoxide synthase: why two isoforms? Am J Physiol 1996;270:G393-400.
18. 18. Zhang Q, Wu WX, Brenna JT, Nathanielsz PW. The expression of cytosolic phospholipase A2 and prostaglandin endoperoxide synthase in ovine maternal uterine and fetal tissues during late gestation and labor. Endocrinology 1996;137:4010-7.
19. 19. Wu WX, Ma XH, Zhang Q, Owiny JR, Nathanielsz PW. Regulation of prostaglandin endoperoxide synthase 1 and 2 by estradiol in non-pregnant ovine myometrium and endometrium (in vivo). Endocrinology 1997;138:4005-12.
20. 20. Nathanielsz PW, Bailey A, Poore ER, Thorburn GD, Harding R. The relationship between myometrial activity and sleep state and breathing in fetal sheep throughout the last third of gestation. Am J Obstet Gynecol 1980;138:653-9.
21. 21. Figueroa JP, Mahan S, Poore ER, Nathanielsz PW. Characteristics and analysis of uterine electromyographic activity in the pregnant sheep. Am J Obstet Gynecol 1985;151:524-31.
22. 22. Otto JC, Smith WL. The orientation of prostaglandin endoperoxide synthase-1 and -2 in the endoplasmic reticulum. J Biol Chem 1994;269:19868-75.
23. 22. Huzar G. Physiology of the uterine cervix in reproduction. Semin Perinatol 1991;15:95-105.
24. 24. Charpigny G, Reinaud P, Tamby JP, Creminon C, Martal J, Maclouf J, et al. Expression of cyclooxygenase-1 and -2 in ovine endometrium during the estrous cycle and early pregnancy. Endocrinology 1997;138:2163-71.
25. 25. Challis JR. Sharp increase in free circulating oestrogens immediately before parturition in sheep. Nature 1971;229:208.