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Volumn 48, Issue 4, 1999, Pages 169-174

Pathophysiology, diagnosis and treatment of Clostridium difficile infection

Author keywords

Antibiotics; Clolitis; Clostridium difficile; Enteric infection; Toxins

Indexed keywords

CLOSTRIDIUM TOXIN; COLESTYRAMINE; IMMUNOGLOBULIN; METRONIDAZOLE; VANCOMYCIN;

EID: 0033375785     PISSN: 00229717     EISSN: None     Source Type: Journal    
DOI: 10.2302/kjm.48.169     Document Type: Review
Times cited : (10)

References (45)
  • 2
    • 0000795948 scopus 로고
    • Intestinal flora in newborn infants, with description of a new pathogenic anaerobe Bacillus difficilis
    • Hall IC, O'Toole E: Intestinal flora in newborn infants, with description of a new pathogenic anaerobe Bacillus difficilis. Am J Dis Child 1935; 49: 390-402
    • (1935) Am J Dis Child , vol.49 , pp. 390-402
    • Hall, I.C.1    O'Toole, E.2
  • 3
  • 4
    • 0025887006 scopus 로고
    • Correlation of immunoblot type, enterotoxin production, and cytotoxin production with clinical manifestations of Clostridium difficile infection in a cohort of hospitalized patients
    • McFarland LV, Elmer GW, Stamm WE, Mulligan ME: Correlation of immunoblot type, enterotoxin production, and cytotoxin production with clinical manifestations of Clostridium difficile infection in a cohort of hospitalized patients. Infect Immun 1991; 59: 2456-2462
    • (1991) Infect Immun , vol.59 , pp. 2456-2462
    • McFarland, L.V.1    Elmer, G.W.2    Stamm, W.E.3    Mulligan, M.E.4
  • 5
    • 0025034688 scopus 로고
    • Epidemiologic markers of Clostridium difficile
    • Tabaqchali S: Epidemiologic markers of Clostridium difficile. Rev Infect Dis 1990; 12(Suppl 2): S192-S199
    • (1990) Rev Infect Dis , vol.12 , Issue.2 SUPPL.
    • Tabaqchali, S.1
  • 6
    • 0025305108 scopus 로고
    • The influence of the normal flora on Clostridium difficile colonisation of the gut
    • Borriello SP: The influence of the normal flora on Clostridium difficile colonisation of the gut. Ann Med 1990; 22: 61-67
    • (1990) Ann Med , vol.22 , pp. 61-67
    • Borriello, S.P.1
  • 7
    • 0024312284 scopus 로고
    • Bacteriotherapy for chronic relapsing Clostridium difficile diarrhoea in six patients
    • Tvede M, Rask-Madsen J: Bacteriotherapy for chronic relapsing Clostridium difficile diarrhoea in six patients. Lancet 1989; 1: 1156-1160
    • (1989) Lancet , vol.1 , pp. 1156-1160
    • Tvede, M.1    Rask-Madsen, J.2
  • 9
    • 0027175513 scopus 로고
    • Clostridium difficile infection associated with antineoplastic chemotherapy: A review
    • Anand A, Glatt AE: Clostridium difficile infection associated with antineoplastic chemotherapy: a review. Clin Infect Dis 1993; 17: 109-113
    • (1993) Clin Infect Dis , vol.17 , pp. 109-113
    • Anand, A.1    Glatt, A.E.2
  • 10
    • 0016208952 scopus 로고
    • Clindamycin-associated colitis. A prospective study
    • Tedesco FJ, Barton RW, Alpers DH: Clindamycin-associated colitis. A prospective study. Ann Intern Med 1974; 81: 429-433
    • (1974) Ann Intern Med , vol.81 , pp. 429-433
    • Tedesco, F.J.1    Barton, R.W.2    Alpers, D.H.3
  • 12
    • 0029942531 scopus 로고    scopus 로고
    • Enteric bacterial toxins: Mechanisms of action and linkage to intestinal secretion
    • Sears CL, Kaper JB: Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion. Microbiol Rev 1996; 60: 167-215
    • (1996) Microbiol Rev , vol.60 , pp. 167-215
    • Sears, C.L.1    Kaper, J.B.2
  • 13
    • 0024204607 scopus 로고
    • Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers
    • Hecht G, Pothoulakis C, LaMont JT, Madara JL: Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers. J Clin Invest 1988; 82: 1516-1524
    • (1988) J Clin Invest , vol.82 , pp. 1516-1524
    • Hecht, G.1    Pothoulakis, C.2    LaMont, J.T.3    Madara, J.L.4
  • 21
    • 0032152205 scopus 로고    scopus 로고
    • Epidemiology, risk factors and treatments for antibiotic-associated diarrhea
    • McFarland LV: Epidemiology, risk factors and treatments for antibiotic-associated diarrhea. Dig Dis 1998; 16: 292-307
    • (1998) Dig Dis , vol.16 , pp. 292-307
    • McFarland, L.V.1
  • 22
    • 0028107662 scopus 로고
    • Epidemiology of community-acquired Clostridium difficile-associated diarrhea
    • Hirschhorn LR, Trnka Y, Onderdonk A, Lee ML, Platt R: Epidemiology of community-acquired Clostridium difficile-associated diarrhea. J Infect Dis 1994; 169: 127-133
    • (1994) J Infect Dis , vol.169 , pp. 127-133
    • Hirschhorn, L.R.1    Trnka, Y.2    Onderdonk, A.3    Lee, M.L.4    Platt, R.5
  • 23
    • 0019497353 scopus 로고
    • Isolation of Clostridium difficile from the environment and contacts of patients with antibiotic-associated colitis
    • Kim KH, Fekety R, Batts DH, Brown D, Cudmore M, Silva J Jr, Waters D: Isolation of Clostridium difficile from the environment and contacts of patients with antibiotic-associated colitis. J Infect Dis 1981; 143: 42-50
    • (1981) J Infect Dis , vol.143 , pp. 42-50
    • Kim, K.H.1    Fekety, R.2    Batts, D.H.3    Brown, D.4    Cudmore, M.5    Silva J., Jr.6    Waters, D.7
  • 24
    • 0032535407 scopus 로고    scopus 로고
    • Acquisition of Clostridium difficile and Clostridium difficile-associated diarrhea in hospitalized patients receiving tube feeding
    • Bliss DZ, Johnson S, Savik K, Clabots CR, Willard K, Gerding DN: Acquisition of Clostridium difficile and Clostridium difficile-associated diarrhea in hospitalized patients receiving tube feeding. Ann Intern Med 1998; 129: 1012-1019
    • (1998) Ann Intern Med , vol.129 , pp. 1012-1019
    • Bliss, D.Z.1    Johnson, S.2    Savik, K.3    Clabots, C.R.4    Willard, K.5    Gerding, D.N.6
  • 25
    • 0025727765 scopus 로고
    • Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin
    • Leung DY, Kelly CP, Boguniewicz M, Pothoulakis C, LaMont JT, Flores A: Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin. J Pediatr 1991; 118: 633-637
    • (1991) J Pediatr , vol.118 , pp. 633-637
    • Leung, D.Y.1    Kelly, C.P.2    Boguniewicz, M.3    Pothoulakis, C.4    LaMont, J.T.5    Flores, A.6
  • 31
    • 0019503053 scopus 로고
    • Epidemiology of antibiotic-associated colitis: Isolation of Clostridium difficile from the hospital environment
    • Fekety R, Kim KH, Brown D, Batts DH, Cudmore M, Silva J Jr: Epidemiology of antibiotic-associated colitis: isolation of Clostridium difficile from the hospital environment. Am J Med 1981; 70: 906-908
    • (1981) Am J Med , vol.70 , pp. 906-908
    • Fekety, R.1    Kim, K.H.2    Brown, D.3    Batts, D.H.4    Cudmore, M.5    Silva J., Jr.6
  • 32
    • 0026663447 scopus 로고
    • Treatment of asymptomatic Clostridium difficile carriers (fecal excretors) with vancomycin or metronidazole. A randomized, placebo-controlled trial
    • Johnson S, Homann SR, Bettin KM, Quick JN, Clabots CR, Peterson LR, Gerding DN: Treatment of asymptomatic Clostridium difficile carriers (fecal excretors) with vancomycin or metronidazole. A randomized, placebo-controlled trial. Ann Intern Med 1992; 117: 297-302
    • (1992) Ann Intern Med , vol.117 , pp. 297-302
    • Johnson, S.1    Homann, S.R.2    Bettin, K.M.3    Quick, J.N.4    Clabots, C.R.5    Peterson, L.R.6    Gerding, D.N.7
  • 33
    • 0025874153 scopus 로고
    • Acute abdomen as the first presentation of pseudomembranous colitis
    • Triadafilopoulos G, Hallstone AE: Acute abdomen as the first presentation of pseudomembranous colitis. Gastroenterology 1991; 101: 685-691
    • (1991) Gastroenterology , vol.101 , pp. 685-691
    • Triadafilopoulos, G.1    Hallstone, A.E.2
  • 34
    • 0026643403 scopus 로고
    • Laboratory diagnosis of Clostridium difficile-associaled gastrointestinal disease: Comparison of a monoclonal antibody enzyme immunoassay for toxins A and B with a monoclonal antibody enzyme immunoassay for toxin A only and two cytotoxicity assays
    • Doern GV, Coughlin RT, Wu L: Laboratory diagnosis of Clostridium difficile-associaled gastrointestinal disease: comparison of a monoclonal antibody enzyme immunoassay for toxins A and B with a monoclonal antibody enzyme immunoassay for toxin A only and two cytotoxicity assays. J Clin Microbiol 1992; 30: 2042-2046
    • (1992) J Clin Microbiol , vol.30 , pp. 2042-2046
    • Doern, G.V.1    Coughlin, R.T.2    Wu, L.3
  • 35
    • 0025839114 scopus 로고
    • Development of a rapid enzyme immunoassay for Clostridium difficile toxin A and its use in the diagnosis of C. difficile-associated disease
    • DiPersio JR, Varga FJ, Conwell DL, Kraft JA, Kozak KJ, Willis DH: Development of a rapid enzyme immunoassay for Clostridium difficile toxin A and its use in the diagnosis of C. difficile-associated disease. J Clin Microbiol 1991; 29: 2724-2730
    • (1991) J Clin Microbiol , vol.29 , pp. 2724-2730
    • DiPersio, J.R.1    Varga, F.J.2    Conwell, D.L.3    Kraft, J.A.4    Kozak, K.J.5    Willis, D.H.6
  • 37
    • 0021038539 scopus 로고
    • Prospective randomised trial of metronidazole versus vancomycin for Clostridium-difficile-associated diarrhoea and colitis
    • Teasley DG, Gerding DN, Olson MM, Peterson LR, Gebhard RL, Schwartz MJ, Lee JT Jr: Prospective randomised trial of metronidazole versus vancomycin for Clostridium-difficile-associated diarrhoea and colitis. Lancet 1983; 2: 1043-1046
    • (1983) Lancet , vol.2 , pp. 1043-1046
    • Teasley, D.G.1    Gerding, D.N.2    Olson, M.M.3    Peterson, L.R.4    Gebhard, R.L.5    Schwartz, M.J.6    Lee J.T., Jr.7
  • 38
    • 0022491104 scopus 로고
    • Faecal metronidazole concentrations during oral and intravenous therapy for antibiotic associated colitis due to Clostridium difficile
    • Bolton RP, Culshaw MA: Faecal metronidazole concentrations during oral and intravenous therapy for antibiotic associated colitis due to Clostridium difficile. Gut 1986; 27: 1169-1172
    • (1986) Gut , vol.27 , pp. 1169-1172
    • Bolton, R.P.1    Culshaw, M.A.2
  • 39
    • 0022703420 scopus 로고
    • Antibiotic-associated colitis: Why do patients relapse?
    • Young G, McDonald M: Antibiotic-associated colitis: why do patients relapse? Gastroenterology 1986; 90: 1098-1099
    • (1986) Gastroenterology , vol.90 , pp. 1098-1099
    • Young, G.1    McDonald, M.2
  • 41
    • 0030969261 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and management of Clostridium difficile-associated diarrhea and colitis
    • American College of Gastroenterology, Practice Parameters Committee
    • Fekety R: Guidelines for the diagnosis and management of Clostridium difficile-associated diarrhea and colitis. American College of Gastroenterology, Practice Parameters Committee. Am J Gastroenterol 1997; 92: 739-750
    • (1997) Am J Gastroenterol , vol.92 , pp. 739-750
    • Fekety, R.1
  • 42
    • 0022348861 scopus 로고
    • Approach to patients with multiple relapses of antibiotic-associated pseudomembranous colitis
    • Tedesco FJ, Gordon D, Fortson WC: Approach to patients with multiple relapses of antibiotic-associated pseudomembranous colitis. Am J Gastroenterol 1985; 80: 867-868
    • (1985) Am J Gastroenterol , vol.80 , pp. 867-868
    • Tedesco, F.J.1    Gordon, D.2    Fortson, W.C.3
  • 43
    • 0024854137 scopus 로고
    • Update on pseudomembranous colitis
    • Silva J Jr: Update on pseudomembranous colitis. West J Med 1989; 151: 644-648
    • (1989) West J Med , vol.151 , pp. 644-648
    • Silva J., Jr.1
  • 45
    • 10544226189 scopus 로고    scopus 로고
    • Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum
    • Castagliuolo I, LaMont JT, Nikulasson ST, Pothoulakis C: Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum. Infect Immun 1996; 64: 5225-5232
    • (1996) Infect Immun , vol.64 , pp. 5225-5232
    • Castagliuolo, I.1    LaMont, J.T.2    Nikulasson, S.T.3    Pothoulakis, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.