Insulin-like-growth-factor-I (IGF-I) antagonizes apoptosis induced by serum deficiency and doxorubicin in neuronal cell culture

Growth Hormone and IGF Research

Volumn 9, Issue 6, 1999, Pages 458-464

  Gil Ad, I ^a   Shtaif, B ^a   Luria, D ^a   Karp, L ^a   Fridman, Y ^a   Weizman, A ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Apoptosis; Cell viability; Doxorubicin; Growth hormone (GH); Insulin like growth factor (IGF) I; Neuroblastoma; Primary neuronal culture

Indexed keywords

DOXORUBICIN; GROWTH HORMONE; SOMATOMEDIN C;

APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG POTENCY; HUMAN; HUMAN CELL; NERVE CELL CULTURE; NEUROBLASTOMA; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; PRIORITY JOURNAL;

EID: 0033374830     PISSN: 10966374     EISSN: None     Source Type: Journal    
DOI: 10.1054/ghir.1999.0130     Document Type: Article

References (31)

1. Adem A., Jossan S. S., D'Argy R., Gillberg P. G., Nordberg A., Windlad B., Sara V. Insulin-like growth factor I (IGF-I) receptors in the human brain. Quantitative autoradiographic localization. Brain Res. 503:1989;299-303.
2. Yamaguchi F., Itano T., Mizobuchi M Miamoto O., Janjua N. A., Matsui H., Tokuda M., Ohmoto T., Hosokawa K., Hatase O. Insulin-like growth factor I (IGF-I) distribution in the tissue and extracellular compartment in different regions of rat brain. Brain Res. 19:1990;533 344-347.
3. Giudice L. C., de Zegher F., Gargosky S. E., Dsupin B. A., De la Fuentes L., Crystal R. A., Hintz R. L., Rosenfeld R. G. Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth. J Clin Endocrinol Metab. 80:1995;1548-1555.
4. Underwood L. E., D'Ercole A. J. Insulin and insulin-like growth factors - somatomedins in fetal and neonatal development. Daughaday W. H. Clinics in Endocrinology and Metabolism. 1984;69-89 W.B Saunders, Philadelphia.
5. Laron Z., Lazar L., Klinger B. Growth hormone, insulin like growth factor I and brain growth and function. Castells S., Weisniewski K. E. Growth Hormones treatment in Down's Syndrome. 1993;151-160 John Wiley & Sons Ltd, Chichester.
6. Park G. H., Buetow D. E. Genes for insulin-like growth factor I and II are expressed in senescent tissues. Gerontology. 37:1991;310-316.
7. Johnston B. M., Mallard E. C., Williams C. E., Gluckman P. D. Insulin-like growth factor I is a potent neuronal rescue agent after hypoxic ischemic injury in fetal lambs. J Clin Invest. 97:1996;300-308.
8. Yao D. L., Liu X., Hudson L. D., Webster H. D. Insulin-like growth factor-I treatment reduces demyelination and up regulates gene expression of myelin related proteins in experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA. 92:1995;6190-6194.
9. Dore S., Kar S., Quirion R. Rediscovering an old friend IGF-I: potential use in the treatment of neurodegenerative diseases. Trends Neurosci. 20:1997;326-331.
10. Zawada W. M., Kirshman D. L., Cohen J. J., Heidenreich K. A., Freed C. R. Growth factors rescue embryonic dopamine neurons from programmed cell death. Exp Neurol. 140:1996;60-67.
11. Wyllie A. H. Apoptosis an overview. British Med Bull. 53:1997;451-465.
12. Rubin L. E. Neuronal cell death: when, why and how. British Med Bull. 53:1997;617-631.
13. Mathews C. C., Feldman E. L. Insulin-like growth factor I (IGF-I) rescues SH-SY5Y human neuroblastoma cells from hyperosmotic induced programmed cell death. J Cell Physiol. 166:1996;323-331.
14. Martin D. M., Singleton J. R., Meghani M. A., Feldman E. L. IGF receptor function and regulation in autocrine human neuroblastoma cell growth. Regul Pept. 48:1993;225-232.
15. Klosen P., Nickmilder M., Van-den-Bosch-de Aguilar P. Effect of adriamycin on axotomized neurons in regeneration chamber model of the peripheral nerve. C R Acad Sci III. 316:1993;43-49.
16. Powis G. Free radical formation by antitumor quinones. Free Radicals Biol Med. 6:1989;53-101.
17. Borenfreund E., Puerner J. A. A simple quantitative procedure using monolayer culture for cytotoxicity assays. (HTD/NR-90). J Tissue Culture Metab. 9:1984;7-9.
18. Vindelov L. L., Christiensen I. J., Nissen N. I. A detergent trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry. 5:1983;323-327.
19. Nicoletti I., Migliorato G., Pagliacci M. L., Gringhami F., Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propodium iodide staining and flow cytometry. J Immunol Methods. 139:199;271-279.
20. Lenoir D., Honneger P. Insulin like growth factor I stimulates DNA synthesis in fetal brain cell cultures. Brain Res. 283:1983;205-213.
21. McMorris F. A., Smith T. M., DeSalvo S., Furlanett R. W. IGF-I/somatomedin C: a potent inducer of oligodendrocyte development. Proc Natl Acad Sci USA. 82:1985;7126-7130.
22. Guan J., Skinner S. J., Beilharz E. J., Hua K. M., Hodgkinson S., Gluckman P. D., Williams C. E. The movement of IGF-I into the brain parenchima after hypoxic-ischaemic injury. Neuroreport. 7:1996;632-636.
23. Tagami M., Ikeda K., Nara Y., Fujino H., Kubota A., Numano F., Yamoi Y. Insulin like growth factor-I attenuates apoptosis in hippocampal neurons caused by cerebral hyschemia and reperfusion in stroke prone spontaneously hypertensive rats. Lab Invest. 76:1997;613-617.
24. Gozes I., Brenneman D. E. Activity-dependent neurotrphic factor (ADNF). An extracellular neuroprotective chaperonin? J Mol Neurosci. 7:1996;235-244.
25. Burke T. W., Vuk-Pavlovic S. Insulin like growth factor-I is a serum component stimulating growth of human neuroblastoma. In Vitro. Cell Dev Biol Anim. 29A:1993;391-394.
26. Badry E. L., Helman L. J., Chatten J., Steinberg S. M., Evans A. E., Israel M. A. Insulin like growth factor II mediated proliferation of human neuroblastoma. J Clin Invest. 87:1991;648-657.
27. Lavenius E., Parrow V., Nanberg E., Pahlman S. Basic FGF and IGF-I promote differentiation of human SH-SY5Y neuroblastoma cells in culture. Growth Factors. 10:1994;29-39.
28. Guo Y. S., Jin G. F., Houston C. W., Thompson J. C., Townsend C. M. Insulin-like growth factor-I promotes multidrug resistance in MCLM colon cancer cells. J Cell Physiol. 175:1998;141-148.
29. Sumantran V. N., Feldman E. L. Insulin like growth factor-I regulates c-myc and GAP-43 mRNA expression in SH-SY5Y human neuroblastoma cells. Endocrinology. 132:1993;2017-2023.
30. Parrizas M., LeRoith D. Insulin like growth factor-I inhibition of apoptosis is associated with increased expression of the Bcl-xL gene product. Endocrinology. 138:1997;1355-1358.
31. Hefti F. Neurotrophic factor therapy for nervous system degenerative diseases. J Neurobiol. 25:1994;1418-1435.