-
1
-
-
0030913459
-
Topotecan, a new active drug in the second-line treatment of small cell lung cancer: A phase I study in patients with refractory and sensitive disease
-
Ardizzoni A., Hansen H., Dombernowsky P., Ganucci T., Kaplan S., Postmus P., Giaccone G., Schaefer B., Wander S., Verweij J.: Topotecan, a new active drug in the second-line treatment of small cell lung cancer: a phase I study in patients with refractory and sensitive disease. J. Clin. Oncol., 15: 2090-2096, 1997.
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 2090-2096
-
-
Ardizzoni, A.1
Hansen, H.2
Dombernowsky, P.3
Ganucci, T.4
Kaplan, S.5
Postmus, P.6
Giaccone, G.7
Schaefer, B.8
Wander, S.9
Verweij, J.10
-
2
-
-
4243401637
-
A phase I-II trial of topotecan (TOP) and gemcitabine (GEM) for patients with previously treated advanced non small cell lung cancer (NSCLC)
-
Cole J.L., Rinaldi D.A., Lormand N.A., Brierre J.E., Barnes B., Fontenot M.F., Buller E.J., Rainey J.: A phase I-II trial of topotecan (TOP) and gemcitabine (GEM) for patients with previously treated advanced non small cell lung cancer (NSCLC). Proc. Am. Soc. Clin. Oncol., 18: 499a, 1999.
-
(1999)
Proc. Am. Soc. Clin. Oncol.
, vol.18
-
-
Cole, J.L.1
Rinaldi, D.A.2
Lormand, N.A.3
Brierre, J.E.4
Barnes, B.5
Fontenot, M.F.6
Buller, E.J.7
Rainey, J.8
-
3
-
-
0003256828
-
Combined therapy with topotecan and gemcitabine in patients with inoperable or metastatic non small cell lung cancer
-
Dabrow M.B., Gilman P.B., Meyer T.J.: Combined therapy with topotecan and gemcitabine in patients with inoperable or metastatic non small cell lung cancer. Proc. Am. Soc. Clin. Oncol., 18: 500a, 1999.
-
(1999)
Proc. Am. Soc. Clin. Oncol.
, vol.18
-
-
Dabrow, M.B.1
Gilman, P.B.2
Meyer, T.J.3
-
4
-
-
0002429272
-
Evualuation of topotecan (hycamtin) in relapsed small cell lung cancer (SCLC). A multicenter phase II study
-
Depierre A., von Pawel J., Hans K., Mono D., Clark J., Gatzemeir V., Paillot N., Scheithauer W., Carmichael J., Santoro A., Ross G., Marangolo M.: Evualuation of topotecan (Hycamtin) in relapsed small cell lung cancer (SCLC). A multicenter phase II study. Lung Cancer; 18 (suppl 1): 13, 1997.
-
(1997)
Lung Cancer
, vol.18
, Issue.SUPPL. 1
, pp. 13
-
-
Depierre, A.1
Von Pawel, J.2
Hans, K.3
Mono, D.4
Clark, J.5
Gatzemeir, V.6
Paillot, N.7
Scheithauer, W.8
Carmichael, J.9
Santoro, A.10
Ross, G.11
Marangolo, M.12
-
5
-
-
0000313636
-
Pooled analysis of topotecan (T) in the second-line treatment of patients (pts) with sensitive small cell lung cancer (SCLC)
-
Eckardt J., Depierre A., Ardizzoni A., von Pawel J., Fields J.: Pooled analysis of topotecan (T) in the second-line treatment of patients (pts) with sensitive small cell lung cancer (SCLC). Proc. Am. Soc. Clin. Oncol., 16: 452a, 1997.
-
(1997)
Proc. Am. Soc. Clin. Oncol.
, vol.16
-
-
Eckardt, J.1
Depierre, A.2
Ardizzoni, A.3
Von Pawel, J.4
Fields, J.5
-
6
-
-
0000580721
-
Topotecan (T) as second-line therapy in patients (pts) with small cell lung cancer (SCLC): A phase II study
-
Eckardt J., Gralla R., Palmer M.C., Gandara D., Laplante J., Sandler A., Fields S.Z., Fitts D., Broom C.: Topotecan (T) as second-line therapy in patients (pts) with small cell lung cancer (SCLC): a phase II study. Ann. Oncol., 7 (suppl 5): 107, 1996.
-
(1996)
Ann. Oncol.
, vol.7
, Issue.SUPPL. 5
, pp. 107
-
-
Eckardt, J.1
Gralla, R.2
Palmer, M.C.3
Gandara, D.4
Laplante, J.5
Sandler, A.6
Fields, S.Z.7
Fitts, D.8
Broom, C.9
-
7
-
-
4243215712
-
Oral topotecan (T) as single agent first line treatment for patients (pts) with extensive disease (ED) small cell lung cancer (SCLC) inelegible for standard IV therapy: A phase II study
-
Eckardt J., Palmer M.C., Fanucchi M., Martins H., Gralla R., Poulin R., Fields S.Z.: Oral topotecan (T) as single agent first line treatment for patients (pts) with extensive disease (ED) small cell lung cancer (SCLC) inelegible for standard IV therapy: a phase II study. Proc. Am. Soc. Clin. Oncol., 18: 501a, 1999.
-
(1999)
Proc. Am. Soc. Clin. Oncol.
, vol.18
-
-
Eckardt, J.1
Palmer, M.C.2
Fanucchi, M.3
Martins, H.4
Gralla, R.5
Poulin, R.6
Fields, S.Z.7
-
8
-
-
0032910847
-
Cisplatin, topotecan, paclitaxel weekly administration with G-CSF support for ovarian and small cell lung cancer patients: A dose-finding study
-
Frasci G., Panza N., Comella P., Cartenì G., Guida T., Nicolella G.P., Natale M., Lombardi R., Apicella A., Pacilio C., Gravina A., Lapenta L., Comella G.: Cisplatin, topotecan, paclitaxel weekly administration with G-CSF support for ovarian and small cell lung cancer patients: a dose-finding study. Ann. Oncol., 10: 355-358, 1999.
-
(1999)
Ann. Oncol.
, vol.10
, pp. 355-358
-
-
Frasci, G.1
Panza, N.2
Comella, P.3
Cartenì, G.4
Guida, T.5
Nicolella, G.P.6
Natale, M.7
Lombardi, R.8
Apicella, A.9
Pacilio, C.10
Gravina, A.11
Lapenta, L.12
Comella, G.13
-
9
-
-
0343792716
-
Topotecan and paclitaxel, an active couplet, in untreated extensive disease small cell lung cancer
-
Jacobs S.A., Jett J.R., Belani C.P., Long G.S., Day R.D., Kim H.D., Levitt M.L., Wooley P.V.: Topotecan and paclitaxel, an active couplet, in untreated extensive disease small cell lung cancer. Lung Cancer; 18 (suppl 1): 13, 1997.
-
(1997)
Lung Cancer
, vol.18
, Issue.SUPPL. 1
, pp. 13
-
-
Jacobs, S.A.1
Jett, J.R.2
Belani, C.P.3
Long, G.S.4
Day, R.D.5
Kim, H.D.6
Levitt, M.L.7
Wooley, P.V.8
-
10
-
-
0001133494
-
Topotecan and paclitaxel, in extensive stage small cell lung cancer (ED-SCLC) patients without prior therapy
-
Jett J.R., Day R., Levitt M., Wooley G., Jacobs S.: Topotecan and paclitaxel, in extensive stage small cell lung cancer (ED-SCLC) patients without prior therapy. Proc. Am. Soc. Clin. Oncol., 18: 470a, 1999.
-
(1999)
Proc. Am. Soc. Clin. Oncol.
, vol.18
-
-
Jett, J.R.1
Day, R.2
Levitt, M.3
Wooley, G.4
Jacobs, S.5
-
11
-
-
0031784642
-
Phase II trial of topotecan administered as a 21-day continuous infusion in previously untreated patients with stage IIIB and IV non small cell lung cancer
-
Kindler H.L., Kris M.G., Smith I.E., Miller V.A., Grant S.L., Krebs J.B., Ross G.A., Slevin M.L.: Phase II trial of topotecan administered as a 21-day continuous infusion in previously untreated patients with stage IIIB and IV non small cell lung cancer. Am. J. Clin. Oncol., 21: 438-441, 1998.
-
(1998)
Am. J. Clin. Oncol.
, vol.21
, pp. 438-441
-
-
Kindler, H.L.1
Kris, M.G.2
Smith, I.E.3
Miller, V.A.4
Grant, S.L.5
Krebs, J.B.6
Ross, G.A.7
Slevin, M.L.8
-
12
-
-
0343792715
-
Response of symptomatic brain metastases of small cell lung cancer (SCLC) to topotecan also after preceeding whole-brain irradiation (WBI)
-
Korfel A., von Pawel J., Dehm E., Keppler U., Deppermann M., Guttler I., Thiel E.: Response of symptomatic brain metastases of small cell lung cancer (SCLC) to topotecan also after preceeding whole-brain irradiation (WBI). Eur. J. Cancer, 35 (suppl 4): S251, 1999.
-
(1999)
Eur. J. Cancer
, vol.35
, Issue.SUPPL. 4
-
-
Korfel, A.1
Von Pawel, J.2
Dehm, E.3
Keppler, U.4
Deppermann, M.5
Guttler, I.6
Thiel, E.7
-
13
-
-
0001125055
-
Toxicity of paclitaxel (P) and topotecan (T) in patients with previuosly untreated extensive small cell lung cancer (E-SCLC)
-
Lynch T.J., Herndon J., Lilenbaum R.C., Lyss A., Miller A.A., Green M.R.: Toxicity of paclitaxel (P) and topotecan (T) in patients with previuosly untreated extensive small cell lung cancer (E-SCLC). Proc. Am. Soc. Clin. Oncol., 18: 515a, 1999.
-
(1999)
Proc. Am. Soc. Clin. Oncol.
, vol.18
-
-
Lynch, T.J.1
Herndon, J.2
Lilenbaum, R.C.3
Lyss, A.4
Miller, A.A.5
Green, M.R.6
-
14
-
-
0028147296
-
Phase II study of topotecan in metastatic non small cell lung cancer
-
Lynch Jr T.J., Kalish L., Strauss G., Elias A., Skarin A., Shulman L.N., Posner M., Frei III E.: Phase II study of topotecan in metastatic non small cell lung cancer. J. Clin. Oncol., 12: 347-352, 1994.
-
(1994)
J. Clin. Oncol.
, vol.12
, pp. 347-352
-
-
Lynch T.J., Jr.1
Kalish, L.2
Strauss, G.3
Elias, A.4
Skarin, A.5
Shulman, L.N.6
Posner, M.7
Frei E. III8
-
15
-
-
0030702834
-
Continuous infusional topotecan in advanced breast and non small cell lung cancer: No evidence of increased efficacy
-
Mainwaring P.N., Nicolson M.C., Hickish T., Penson R., Joel S., Slevin M., Smith I.E.: Continuous infusional topotecan in advanced breast and non small cell lung cancer: no evidence of increased efficacy. Br. J. Cancer; 76: 1636-1639, 1997.
-
(1997)
Br. J. Cancer
, vol.76
, pp. 1636-1639
-
-
Mainwaring, P.N.1
Nicolson, M.C.2
Hickish, T.3
Penson, R.4
Joel, S.5
Slevin, M.6
Smith, I.E.7
-
16
-
-
0000760094
-
Response of SCLC brain metastases on topotecan (SKF 104864) therapy
-
Manegold C., von Pawel J., Scheithauer W., Lan J., Schaefer B., Pastovic R., Staab H.J.: Response of SCLC brain metastases on topotecan (SKF 104864) therapy. Ann. Oncol., 7 (suppl 5): 106, 1996.
-
(1996)
Ann. Oncol.
, vol.7
, Issue.SUPPL. 5
, pp. 106
-
-
Manegold, C.1
Von Pawel, J.2
Scheithauer, W.3
Lan, J.4
Schaefer, B.5
Pastovic, R.6
Staab, H.J.7
-
17
-
-
0038154762
-
Phase II trial of topotecan and cyclophopshamide (Cy) with G-CSF in high-risk small cell lung cancer (SCLC)
-
Murren J., Kraut E., Balcerzak S., Gams R., Galloway S., Schultz M., Masters G., Chang A.: Phase II trial of topotecan and cyclophopshamide (Cy) with G-CSF in high-risk small cell lung cancer (SCLC). Proc. Am. Soc. Clin. Oncol., 17: 495a, 1998.
-
(1998)
Proc. Am. Soc. Clin. Oncol.
, vol.17
-
-
Murren, J.1
Kraut, E.2
Balcerzak, S.3
Gams, R.4
Galloway, S.5
Schultz, M.6
Masters, G.7
Chang, A.8
-
18
-
-
0342487520
-
Cisplatin, paclitaxel, topotecan (CPT) weekly administration in chemo-naive or pretreated extensive disease small cell lung cancer (EL-SCLC). A SICOG phase II study
-
Panza N., Frasci G., Comella P., Nicolella G., Natale M., Muci D., Palmieri S., Ruffolo P., Gravina A., Comella G.: Cisplatin, paclitaxel, topotecan (CPT) weekly administration in chemo-naive or pretreated extensive disease small cell lung cancer (EL-SCLC). A SICOG phase II study. Eur. J. Cancer; 35 (suppl 4): S252, 1999.
-
(1999)
Eur. J. Cancer
, vol.35
, Issue.SUPPL. 4
-
-
Panza, N.1
Frasci, G.2
Comella, P.3
Nicolella, G.4
Natale, M.5
Muci, D.6
Palmieri, S.7
Ruffolo, P.8
Gravina, A.9
Comella, G.10
-
19
-
-
0004484604
-
Phase II study of topotecan in patients with advanced non small cell lung cancer previously untreated with chemotherapy
-
Perez-Soler R., Fossella F.V., Glisson B.S., Lee J.S., Murphy W.K., Shin D.M., Kemp B.L., Lee J.J., Kane J., Robinson R.A., Lippman S.M., Kurie J.M., Huber M.H., Raber M.N., Hong W.K.: Phase II study of topotecan in patients with advanced non small cell lung cancer previously untreated with chemotherapy. J. Clin. Oncol., 14: 503-513, 1996.
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 503-513
-
-
Perez-Soler, R.1
Fossella, F.V.2
Glisson, B.S.3
Lee, J.S.4
Murphy, W.K.5
Shin, D.M.6
Kemp, B.L.7
Lee, J.J.8
Kane, J.9
Robinson, R.A.10
Lippman, S.M.11
Kurie, J.M.12
Huber, M.H.13
Raber, M.N.14
Hong, W.K.15
-
20
-
-
0029758947
-
Treatment of refractory patients with non small cell lung cancer refractory to etoposide and cisplatin with the topoisomerase I poison topotecan
-
Perez-Soler R., Glisson B.S., Lee J.S., Fossella F.V., Murphy W.K., Skin D.M., Hong W.K.: Treatment of refractory patients with non small cell lung cancer refractory to etoposide and cisplatin with the topoisomerase I poison topotecan. J. Clin. Oncol., 14: 2785-2790, 1996.
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 2785-2790
-
-
Perez-Soler, R.1
Glisson, B.S.2
Lee, J.S.3
Fossella, F.V.4
Murphy, W.K.5
Skin, D.M.6
Hong, W.K.7
-
21
-
-
0005959072
-
Phase I trial of topotecan, paclitaxel and carboplatin in patients with advanced refractory malignancies
-
Raefsky E.L., Hainsworth J.D., Burris H.A., Hopkins L.G., Greco F.A.: Phase I trial of topotecan, paclitaxel and carboplatin in patients with advanced refractory malignancies, Proc. Am. Soc. Clin. Oncol., 17: 498a, 1998.
-
(1998)
Proc. Am. Soc. Clin. Oncol.
, vol.17
-
-
Raefsky, E.L.1
Hainsworth, J.D.2
Burris, H.A.3
Hopkins, L.G.4
Greco, F.A.5
-
22
-
-
0030720766
-
Phase I study of daily times five topotecan and single injection of cisplatin in patients with previously untreated non small cell lung cancer
-
Raymond E., Burris H.A., Rowinsky E.K., Eckardt J.R., Rodriguez G., Smith L., Welss G., von Hoff D.D.: Phase I study of daily times five topotecan and single injection of cisplatin in patients with previously untreated non small cell lung cancer. Ann. Oncol., 8: 1003-1008, 1997.
-
(1997)
Ann. Oncol.
, vol.8
, pp. 1003-1008
-
-
Raymond, E.1
Burris, H.A.2
Rowinsky, E.K.3
Eckardt, J.R.4
Rodriguez, G.5
Smith, L.6
Welss, G.7
Von Hoff, D.D.8
-
23
-
-
0029790139
-
Phase II study of topotecan in patients with extensive stage small cell carcinoma of the lung: An Eastern Cooperative Oncology Group trial
-
Schiller J.H., Kim K., Hutson P., Devore R., Glick J., Stewart J., Johnson D.: Phase II study of topotecan in patients with extensive stage small cell carcinoma of the lung: an Eastern Cooperative Oncology Group trial. J. Clin. Oncol., 14: 2345-2352, 1996.
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 2345-2352
-
-
Schiller, J.H.1
Kim, K.2
Hutson, P.3
Devore, R.4
Glick, J.5
Stewart, J.6
Johnson, D.7
-
24
-
-
0009103030
-
Phase I/IIa study of sequential ifosfamide (I) and topotecan (T) in patients with small cell lung cancer
-
Smith M.J., Spencer S.A., Zhang R., Robert F.: Phase I/IIa study of sequential ifosfamide (I) and topotecan (T) in patients with small cell lung cancer. Proc. Am. Soc. Clin. Oncol., 17: 500a, 1998.
-
(1998)
Proc. Am. Soc. Clin. Oncol.
, vol.17
-
-
Smith, M.J.1
Spencer, S.A.2
Zhang, R.3
Robert, F.4
-
25
-
-
0007952209
-
Phase I/II study of topotecan and cisplatin alternating with carboplatin, cisplatin, teniposide and vincristine in previously untreated patients with small cell lung cancer
-
Sorensen M., Sensen P.B., Sehested M., Hirsch F.R., Hansen H.H.: Phase I/II study of topotecan and cisplatin alternating with carboplatin, cisplatin, teniposide and vincristine in previously untreated patients with small cell lung cancer. Proc. Am. Soc. Clin. Oncol., 17: 501a, 1998.
-
(1998)
Proc. Am. Soc. Clin. Oncol.
, vol.17
-
-
Sorensen, M.1
Sensen, P.B.2
Sehested, M.3
Hirsch, F.R.4
Hansen, H.H.5
-
26
-
-
0000255552
-
Topotecan and paclitaxel in extensive stage small cell lung cancer as initial therapy
-
Tweedy C.R., Andrews D.F., Ball T.: Topotecan and paclitaxel in extensive stage small cell lung cancer as initial therapy. Proc. Am. Soc. Clin. Oncol., 18: 525a, 1999.
-
(1999)
Proc. Am. Soc. Clin. Oncol.
, vol.18
-
-
Tweedy, C.R.1
Andrews, D.F.2
Ball, T.3
-
27
-
-
0342487515
-
Topotecan (hycamtin) in small cell lung cancer (SCLC) after failure of first line therapy: Multicenter phase II study. The European Cancer Conference
-
September
-
von Pawel J., Depierre A., Hans K.: Topotecan (Hycamtin) in small cell lung cancer (SCLC) after failure of first line therapy: multicenter phase II study. The European Cancer Conference, Poster 1038, September, 1997.
-
(1997)
Poster
, vol.1038
-
-
Von Pawel, J.1
Depierre, A.2
Hans, K.3
-
28
-
-
0000292007
-
A multicenter randomised phase II study of oral topotecan versus IV topotecan for second line therapy in sensitive patients with small cell lung cancer
-
von Pawel J., Gatzmeier V., Harstrick A., Ronson M., Richardson G., Steppert K., Comlett I., Lane S., Ross G.: A multicenter randomised phase II study of oral topotecan versus IV topotecan for second line therapy in sensitive patients with small cell lung cancer. Proc. Am. Soc. Clin. Oncol., 18: 471a, 1999.
-
(1999)
Proc. Am. Soc. Clin. Oncol.
, vol.18
-
-
Von Pawel, J.1
Gatzmeier, V.2
Harstrick, A.3
Ronson, M.4
Richardson, G.5
Steppert, K.6
Comlett, I.7
Lane, S.8
Ross, G.9
-
29
-
-
0033044111
-
Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small cell lung cancer
-
von Pawel J., Schriller J.H., Shepherd F.A., Fields S.Z., Kleisbauer J.P., Chrysson N.G., Stewart D.J., Clark P.I., Palmer M.C., Depierre A., Carmichael J., Krebs J.B., Ross G., Lane S.R., Gralla R.: Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small cell lung cancer. J. Clin. Oncol., 17: 658-667, 1999.
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 658-667
-
-
Von Pawel, J.1
Schriller, J.H.2
Shepherd, F.A.3
Fields, S.Z.4
Kleisbauer, J.P.5
Chrysson, N.G.6
Stewart, D.J.7
Clark, P.I.8
Palmer, M.C.9
Depierre, A.10
Carmichael, J.11
Krebs, J.B.12
Ross, G.13
Lane, S.R.14
Gralla, R.15
-
30
-
-
0343356793
-
A randomized phase II study of topotecan (TOP) and cisplatin (CDDP) with filgrastim (G-CSF) versus topotecan and paclitaxel (taxol) with filgrastim in patients with advanced non small cell lung cancer
-
Wiesenfeld M., Marks R., Grill J., Sloan J., Tazeelar H., Carrol T., Kugler J., Krook J.: A randomized phase II study of topotecan (TOP) and cisplatin (CDDP) with filgrastim (G-CSF) versus topotecan and paclitaxel (taxol) with filgrastim in patients with advanced non small cell lung cancer. Proc. Am. Soc. Clin. Oncol., 18: 527a, 1999.
-
(1999)
Proc. Am. Soc. Clin. Oncol.
, vol.18
-
-
Wiesenfeld, M.1
Marks, R.2
Grill, J.3
Sloan, J.4
Tazeelar, H.5
Carrol, T.6
Kugler, J.7
Krook, J.8
-
31
-
-
4243493887
-
A phase II study of oral topotecan in advanced non small cell lung cancer: Useful symptom palliation and 10 months median survival
-
White S.C., Cheeseman S., Anderson H., Thatcher N., Hearn S., Ross G., Ranson M.: A phase II study of oral topotecan in advanced non small cell lung cancer: useful symptom palliation and 10 months median survival. Proc. Am. Soc. Clin. Oncol., 16:488a, 1997.
-
(1997)
Proc. Am. Soc. Clin. Oncol.
, vol.16
-
-
White, S.C.1
Cheeseman, S.2
Anderson, H.3
Thatcher, N.4
Hearn, S.5
Ross, G.6
Ranson, M.7
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