-
1
-
-
0029346911
-
The abnormal isoform of the prion protein accumulates in late-endosome-like organelles in scrapie-infected mouse brain
-
ARNOLD, J. E., TIPLER, C., LASZLO, L., HOPE, J., LANDON, M. & MAYER, R. J. (1995). The abnormal isoform of the prion protein accumulates in late-endosome-like organelles in scrapie-infected mouse brain. Journal of Pathology 176, 403-11.
-
(1995)
Journal of Pathology
, vol.176
, pp. 403-411
-
-
Arnold, J.E.1
Tipler, C.2
Laszlo, L.3
Hope, J.4
Landon, M.5
Mayer, R.J.6
-
2
-
-
0026775909
-
Evidence for synthesis of scrapie prion proteins in the endocytic pathway
-
BORCHELT, D. R., TARABOULOS, A. & PRUSINER, S. B. (1992) Evidence for synthesis of scrapie prion proteins in the endocytic pathway. Journal of Biological Chemistry 267, 16188-199.
-
(1992)
Journal of Biological Chemistry
, vol.267
, pp. 16188-16199
-
-
Borchelt, D.R.1
Taraboulos, A.2
Prusiner, S.B.3
-
3
-
-
0030054010
-
Normal host prion protein necessary for scrapie-induced neurotoxity
-
BRANDNER, S., ISENMANN, S., RAEBER, A., FISCHER, M., SAILER, A., KOBAYASHI, Y., MARINO, S., WEISSMANN, C. & AGUZZI, A. (1996) Normal host prion protein necessary for scrapie-induced neurotoxity. Nature 379, 339-43.
-
(1996)
Nature
, vol.379
, pp. 339-343
-
-
Brandner, S.1
Isenmann, S.2
Raeber, A.3
Fischer, M.4
Sailer, A.5
Kobayashi, Y.6
Marino, S.7
Weissmann, C.8
Aguzzi, A.9
-
4
-
-
0028143841
-
Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment
-
BROWN, D. R., HERMS, J. & KRETZSCHMAR, H. A. (1994) Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment. NeuroReport 5, 2057-60.
-
(1994)
NeuroReport
, vol.5
, pp. 2057-2060
-
-
Brown, D.R.1
Herms, J.2
Kretzschmar, H.A.3
-
5
-
-
0029997484
-
Role of microglia and host prion protein in neurotoxicity of prion protein fragment
-
BROWN, D. R., SCHMIDT, B. & KRETZSCHMAR, H. A. (1996a) Role of microglia and host prion protein in neurotoxicity of prion protein fragment. Nature 380, 345-47.
-
(1996)
Nature
, vol.380
, pp. 345-347
-
-
Brown, D.R.1
Schmidt, B.2
Kretzschmar, H.A.3
-
6
-
-
0030250917
-
A neurotoxic prion protein fragment enhances proliferation of microglia but not astrocytes in culture
-
BROWN, D. R., SCHMIDT, B. AND KRETZSCHMAR, H. A. (1996b) A neurotoxic prion protein fragment enhances proliferation of microglia but not astrocytes in culture. Glia 18, 59-67.
-
(1996)
Glia
, vol.18
, pp. 59-67
-
-
Brown, D.R.1
Schmidt, B.2
Kretzschmar, H.A.3
-
7
-
-
0031444294
-
The cellular prion protein binds copper in vivo
-
BROWN, D. R., QIN, K., HERMS, J. W., MADLUNG, MANSON, J., STROME, R., FRASER, P. E., KRUCK, T., A., VON BOHLEN, A., SCHULZ-SCHAEFFER, W., GIESE, A., WESTAWAY, D. & KRETZSCHMAR, H. A. (1997a) The cellular prion protein binds copper in vivo. Nature 390, 684-87.
-
(1997)
Nature
, vol.390
, pp. 684-687
-
-
Brown, D.R.1
Qin, K.2
Herms, J.W.3
Madlung4
Manson, J.5
Strome, R.6
Fraser, P.E.7
Kruck, T.A.8
Von Bohlen, A.9
Schulz-Schaeffer, W.10
Giese, A.11
Westaway, D.12
Kretzschmar, H.A.13
-
8
-
-
0031194455
-
Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity
-
BROWN, D. R., SCHULZ-SCHAEFFER, W. J., SCHMIDT, B. & KRETZSCHMAR, H. A. (1997b) Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Experimental Neurology 146, 104-12.
-
(1997)
Experimental Neurology
, vol.146
, pp. 104-112
-
-
Brown, D.R.1
Schulz-Schaeffer, W.J.2
Schmidt, B.3
Kretzschmar, H.A.4
-
9
-
-
0030925694
-
Different requirements for the neurotoxicity of fragments of PrP and β-amyloid
-
BROWN, D. R., HERMS, J. W., SCHMIDT, B. & KRETZSCHMAR, H. A. (1997c) Different requirements for the neurotoxicity of fragments of PrP and β-amyloid. European Journal of Neuroscience 9, 1162-69.
-
(1997)
European Journal of Neuroscience
, vol.9
, pp. 1162-1169
-
-
Brown, D.R.1
Herms, J.W.2
Schmidt, B.3
Kretzschmar, H.A.4
-
10
-
-
0031937973
-
Prion protein expression in muscle cells and toxicity of a prion protein fragment
-
BROWN, D. R., SCHMIDT, B., GROSCHUP, M. H. & KRETZSCHMAR, H. A. (1998a) Prion protein expression in muscle cells and toxicity of a prion protein fragment. European Journal of Cell Biology 75, 29-37.
-
(1998)
European Journal of Cell Biology
, vol.75
, pp. 29-37
-
-
Brown, D.R.1
Schmidt, B.2
Groschup, M.H.3
Kretzschmar, H.A.4
-
11
-
-
0032507653
-
Microglial expression of the prion protein
-
BROWN, D. R., BESINGER, A., HERMS, J. W. & KRETZSCHMAR, H. A. (1998b) Microglial expression of the prion protein. NeuroReport 9, 1425-29.
-
(1998)
NeuroReport
, vol.9
, pp. 1425-1429
-
-
Brown, D.R.1
Besinger, A.2
Herms, J.W.3
Kretzschmar, H.A.4
-
12
-
-
0031731390
-
Cellular effects of a neurotoxic prion protein peptide are related to its β-sheet content
-
BROWN, D. R., PITSCHKE, M., RIESNER, D. & KRETZSCHMAR, H. A. (1998c) Cellular effects of a neurotoxic prion protein peptide are related to its β-sheet content. Neuroscience Research Communications 23, 119-28.
-
(1998)
Neuroscience Research Communications
, vol.23
, pp. 119-128
-
-
Brown, D.R.1
Pitschke, M.2
Riesner, D.3
Kretzschmar, H.A.4
-
13
-
-
0032080434
-
A prion protein fragment interacts with PrP-deficient cells
-
BROWN, D. R., SCHMIDT, B. & KRETZSCHMAR, H. A. (1998d) A prion protein fragment interacts with PrP-deficient cells. Journal of Neuroscience Research 52, 260-67.
-
(1998)
Journal of Neuroscience Research
, vol.52
, pp. 260-267
-
-
Brown, D.R.1
Schmidt, B.2
Kretzschmar, H.A.3
-
14
-
-
0008920990
-
Toxicity of a β-amyloid peptide fragment in neurones and glia with reduced APP expression
-
BROWN, D. R. (1998) Toxicity of a β-amyloid peptide fragment in neurones and glia with reduced APP expression. Alzheimer's Reports 1, 223-31.
-
(1998)
Alzheimer's Reports
, vol.1
, pp. 223-231
-
-
Brown, D.R.1
-
15
-
-
0025270288
-
The mRNA encoding the scrapie agent is present in a variety of non-neuronal cells
-
BROWN, H. R., GOLLER, N. L., RUDELLI, R. D., MERZ, G. S., WOLFE, G. S., WISNIEWSKI, H. M & ROBAKIS, N. K. (1990). The mRNA encoding the scrapie agent is present in a variety of non-neuronal cells. Acta Neuropathologica 80, 1-6.
-
(1990)
Acta Neuropathologica
, vol.80
, pp. 1-6
-
-
Brown, H.R.1
Goller, N.L.2
Rudelli, R.D.3
Merz, G.S.4
Wolfe, G.S.5
Wisniewski, H.M.6
Robakis, N.K.7
-
16
-
-
0026600865
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
-
BÜELER, H., FISCHER, M., LANG, Y., BLUETHMANN, H., LIPP, H.-P., DEARMOND, S. J., PRUSINER, S. B., AGUET, M. & WEISSMANN, C. (1992) Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 356, 577-82.
-
(1992)
Nature
, vol.356
, pp. 577-582
-
-
Büeler, H.1
Fischer, M.2
Lang, Y.3
Bluethmann, H.4
Lipp, H.-P.5
Dearmond, S.J.6
Prusiner, S.B.7
Aguet, M.8
Weissmann, C.9
-
17
-
-
0027319326
-
Mice devoid of PrP are resistent to scrapie
-
BÜELER, H., AGUZZI, A., SAILER, A., GREINER, R.-A., P., A., AUGET, M. & WEISSMANN, C. (1993) Mice devoid of PrP are resistent to scrapie. Cell 73, 1339-47.
-
(1993)
Cell
, vol.73
, pp. 1339-1347
-
-
Büeler, H.1
Aguzzi, A.2
Sailer, A.3
Greiner, R.-A.4
Auget, M.5
Weissmann, C.6
-
18
-
-
0025212147
-
Cellular isoforms of the scrapie agent protein participates in lymphocyte activation
-
CASHMAN, N. R., LOERTSCHER, R., NALBANTO-GLU, T., SHAW, I., KASCSAK, R. J., BOLTON, D. C. & BENDHEIM, P. E. (1990). Cellular isoforms of the scrapie agent protein participates in lymphocyte activation. Cell 61, 185-92.
-
(1990)
Cell
, vol.61
, pp. 185-192
-
-
Cashman, N.R.1
Loertscher, R.2
Nalbanto-Glu, T.3
Shaw, I.4
Kascsak, R.J.5
Bolton, D.C.6
Bendheim, P.E.7
-
19
-
-
0029966011
-
Clusterin (SGP-2) induction in rat astroglial cells exposed to prion protein fragment 106-126
-
CHIESA, R., ANGERETTI, N., LUCCA, E., SALMONA, M., TAGLIAVINI, F., BUGIANI, O. & FORLONI, G. (1996) Clusterin (SGP-2) induction in rat astroglial cells exposed to prion protein fragment 106-126. European Journal of Neuroscience 8, 589-97.
-
(1996)
European Journal of Neuroscience
, vol.8
, pp. 589-597
-
-
Chiesa, R.1
Angeretti, N.2
Lucca, E.3
Salmona, M.4
Tagliavini, F.5
Bugiani, O.6
Forloni, G.7
-
20
-
-
0025967257
-
Scrapie-associated prion protein accumulates in astrocytes during scrapie infection
-
DIEDRICH, J. F., BENDHEIM, P. E., KIM, Y. S., CARP, R.I., & HAASE, A (1991) Scrapie-associated prion protein accumulates in astrocytes during scrapie infection. Proceedings of the National Academy of Sciences USA 88, 375-79.
-
(1991)
Proceedings of the National Academy of Sciences USA
, vol.88
, pp. 375-379
-
-
Diedrich, J.F.1
Bendheim, P.E.2
Kim, Y.S.3
Carp, R.I.4
Haase, A.5
-
21
-
-
0027483615
-
Neurotoxicity of a prion protein fragment
-
FORLONI, G., ANGERETTI, N., CHIESA, R., MONZANI, E., SALMONA, M., BUGIANI, O. & TAGLIAVINI, F. (1993) Neurotoxicity of a prion protein fragment. Nature 362, 543-46.
-
(1993)
Nature
, vol.362
, pp. 543-546
-
-
Forloni, G.1
Angeretti, N.2
Chiesa, R.3
Monzani, E.4
Salmona, M.5
Bugiani, O.6
Tagliavini, F.7
-
22
-
-
0031803512
-
Role of microglia in neuronal cell death in prion disease
-
GIESE, A., BROWN, D. R., GROSCHUP, M. H., FELDMANN, C., HAIST, I. & KRETZSCHMAR, H. A. (1998) Role of microglia in neuronal cell death in prion disease. Brain Pathology 8, 449-57.
-
(1998)
Brain Pathology
, vol.8
, pp. 449-457
-
-
Giese, A.1
Brown, D.R.2
Groschup, M.H.3
Feldmann, C.4
Haist, I.5
Kretzschmar, H.A.6
-
24
-
-
0029964280
-
Cytotoxicity of prion protein (PrP106-126) differs in mechanism from the cytotoxicity activity of the Alzheimer's disease amyloid peptide aβ25-35
-
HOPE, J., SHEARMAN, M. S., BAXTER, H. C., CHONG, A., KELLY, S. M. & PRICE, N. C. (1996) Cytotoxicity of prion protein (PrP106-126) differs in mechanism from the cytotoxicity activity of the Alzheimer's disease amyloid peptide Aβ25-35. Neurodegeneration 5, 1-11.
-
(1996)
Neurodegeneration
, vol.5
, pp. 1-11
-
-
Hope, J.1
Shearman, M.S.2
Baxter, H.C.3
Chong, A.4
Kelly, S.M.5
Price, N.C.6
-
25
-
-
0027982241
-
Correlative light and electron microscopy of PrP localization in 87v scrapie
-
JEFFREY, M., GOODSIR, C. M., BRUCE, M. E. & MCBRIDE, P. A., SCOTT, J. R. & HALLIDAY, W. G. (1994). Correlative light and electron microscopy of PrP localization in 87v scrapie. Brain Research 656, 329-43.
-
(1994)
Brain Research
, vol.656
, pp. 329-343
-
-
Jeffrey, M.1
Goodsir, C.M.2
Bruce, M.E.3
Mcbride, P.A.4
Scott, J.R.5
Halliday, W.G.6
-
27
-
-
0029299190
-
Immunohistochemical detection and localization of prion protein in brain tissue of sheep with natural scrapie
-
VAN KEULEN, L. J. M., SCHREUDER, B. E. C., MELOEN, R. H., POELEN-VAN DER BERG, M., MOOIJ-HARKES, G., VROMANS, M. E. W. & LANGEVALD, J. P. M. (1995) Immunohistochemical detection and localization of prion protein in brain tissue of sheep with natural scrapie. Veterinary Pathology 32, 299-308.
-
(1995)
Veterinary Pathology
, vol.32
, pp. 299-308
-
-
Van Keulen, L.J.M.1
Schreuder, B.E.C.2
Meloen, R.H.3
Poelen-Van Der Berg, M.4
Mooij-Harkes, G.5
Vromans, M.E.W.6
Langevald, J.P.M.7
-
28
-
-
0022569404
-
Scrapie prion proteins are synthesized in neurons
-
KRETZSCHMAR, H. A., PRUSINER, S. B., STOWRING, L. E. & DEARMOND, S. J. (1986) Scrapie prion proteins are synthesized in neurons. American Journal of Pathology 122, 1-5.
-
(1986)
American Journal of Pathology
, vol.122
, pp. 1-5
-
-
Kretzschmar, H.A.1
Prusiner, S.B.2
Stowring, L.E.3
Dearmond, S.J.4
-
29
-
-
0021847557
-
Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of Alzheimer type and Down's syndrome in middle age
-
MANN, D. M. A., YATES, P. O. & MARCYNUIK, B. (1985) Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of Alzheimer type and Down's syndrome in middle age. Journal of Neurological Sciences 69, 139-59.
-
(1985)
Journal of Neurological Sciences
, vol.69
, pp. 139-159
-
-
Mann, D.M.A.1
Yates, P.O.2
Marcynuik, B.3
-
30
-
-
0026637514
-
The prion protein gene: A role in mouse embryo-genesis?
-
MANSON, J., WEST, D. J., THOMSON, V., MCBRIDE, P., KAUFMAN, M. H. & HOPE, J. (1992). The prion protein gene: A role in mouse embryo-genesis? Development 115, 117-22.
-
(1992)
Development
, vol.115
, pp. 117-122
-
-
Manson, J.1
West, D.J.2
Thomson, V.3
Mcbride, P.4
Kaufman, M.H.5
Hope, J.6
-
31
-
-
0031466157
-
Complementary hydropathy identifies a cellular prion protein receptor
-
MARTINS, V. R., GRANER, E., GARCIA-ABREU, J., DE SOUZA, S. J., MERCADANTE, A. F., VEIGA, S. S., ZANATA, S. M., NETO, V. M. & BRENTANI, R. R. (1997) Complementary hydropathy identifies a cellular prion protein receptor. Nature Medicine 3, 1376-82.
-
(1997)
Nature Medicine
, vol.3
, pp. 1376-1382
-
-
Martins, V.R.1
Graner, E.2
Garcia-Abreu, J.3
De Souza, S.J.4
Mercadante, A.F.5
Veiga, S.S.6
Zanata, S.M.7
Neto, V.M.8
Brentani, R.R.9
-
32
-
-
0040393220
-
Separation and properties of cellular and scrapie prion proteins
-
MEYER, R. K., MCKINLEY, M. P., BOWMAN, K. A., BRAUNFELD, M. B., BARRY, R. A. & PRUSINER, S. B. (1986) Separation and properties of cellular and scrapie prion proteins. Proceedings of the National Academy of Sciences USA 83, 2310-14.
-
(1986)
Proceedings of the National Academy of Sciences USA
, vol.83
, pp. 2310-2314
-
-
Meyer, R.K.1
Mckinley, M.P.2
Bowman, K.A.3
Braunfeld, M.B.4
Barry, R.A.5
Prusiner, S.B.6
-
33
-
-
0028902465
-
Developmental expression of the prion protein gene in glial cells
-
MOSER, M., COLELLO, R. J., POTT, U., & OESCH, B, (1995) Developmental expression of the prion protein gene in glial cells. Neuron 14, 509-17.
-
(1995)
Neuron
, vol.14
, pp. 509-517
-
-
Moser, M.1
Colello, R.J.2
Pott, U.3
Oesch, B.4
-
34
-
-
0025910229
-
Molecular biology of prion disease
-
PRUSINER, S. B.M (1991) Molecular biology of prion disease. Science 252, 1515-22.
-
(1991)
Science
, vol.252
, pp. 1515-1522
-
-
Prusiner, S.B.M.1
-
35
-
-
0030719529
-
A neurotoxic and gliotrophic fragment of the prion protein increases plasma membrane microviscosity
-
SALMONA, M., FORLONI, G., DIOMEDE, L., ALGERI, M., DEGIOLA, L., ANGERETTI, N., GIACCONE, G., TAGLIAVINI, F. & BUGIANI, O. (1997) A neurotoxic and gliotrophic fragment of the prion protein increases plasma membrane microviscosity. Neurobiology of Disease4, 47-57.
-
(1997)
Neurobiology of Disease
, vol.4
, pp. 47-57
-
-
Salmona, M.1
Forloni, G.2
Diomede, L.3
Algeri, M.4
Degiola, L.5
Angeretti, N.6
Giaccone, G.7
Tagliavini, F.8
Bugiani, O.9
-
36
-
-
0027259274
-
Molecular characteristics of a protease-resistant, amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein
-
SELVAGGINI, C., DE GIOIA, L., GHIBAUDI, E., DIOMEDE, L., PASSERINI, F., BUGIANI, O., TAGLIAVINI, F. & SALMONA, M. (1993). Molecular characteristics of a protease-resistant, amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein. Biochemical and Biophysical Research Communications 194, 1380-86.
-
(1993)
Biochemical and Biophysical Research Communications
, vol.194
, pp. 1380-1386
-
-
Selvaggini, C.1
De Gioia, L.2
Ghibaudi, E.3
Diomede, L.4
Passerini, F.5
Bugiani, O.6
Tagliavini, F.7
Salmona, M.8
-
37
-
-
0029962468
-
Subcellular colocalization of the cellular and scrapie prion proteins in calveolae-like membranous domains
-
VEY, M., PILKUHN, S., WILLE, H., NIXON, R., DEARMOND, S. J., SMART, E. J., ANDERSON, R. G. W., TARABOULOS, A. & PRUSINER, S. B. (1996) Subcellular colocalization of the cellular and scrapie prion proteins in calveolae-like membranous domains. Proceedings of the National Academy of Sciences USA 93, 14945-49.
-
(1996)
Proceedings of the National Academy of Sciences USA
, vol.93
, pp. 14945-14949
-
-
Vey, M.1
Pilkuhn, S.2
Wille, H.3
Nixon, R.4
Dearmond, S.J.5
Smart, E.J.6
Anderson, R.G.W.7
Taraboulos, A.8
Prusiner, S.B.9
-
38
-
-
0024990330
-
Neurotrophic and neurotoxic effects of amyloid β protein: Reversal by tachykinin neuropeptides
-
YANKER, B. A., DUFFY, L. K. & KIRSCHNER, D. A. (1990). Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science 25, 279-82.
-
(1990)
Science
, vol.25
, pp. 279-282
-
-
Yanker, B.A.1
Duffy, L.K.2
Kirschner, D.A.3
|