PrP and β-amyloid fragments activate different neurotoxic mechanisms in cultured mouse cells

European Journal of Neuroscience

Volumn 9, Issue 6, 1997, Pages 1162-1169

  Kretzschmar, Hans A ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Amyloid; Neurotoxicity; Prion; PrP

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CALCIUM CHANNEL; CALCIUM ION; CELL PROTEIN; CYCLIC AMP; FORSKOLIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PRION PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; DEPOLARIZATION; EMBRYO; MICROGLIA; MOUSE; NERVE CELL CULTURE; NEUROTOXICITY; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; ANIMALS; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; CYCLIC AMP; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; MOLECULAR SEQUENCE DATA; NEURONS; NEUROTOXINS; PEPTIDE FRAGMENTS; PRIONS;

EID: 0030925694     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1997.tb01470.x     Document Type: Article

References (2)

1. Arispe, N., Pollard, H. B. and Rojas, E. (1993) Giant multilevel cation channels formed by Alzheimer disease amyloid-β protein [AβP-(1-40)] in bilayer membranes. Proc. Natl Acad. Sci. USA, 90, 10573-10577.
2. +-stimulation. J. Neurosci. Res., 33, 436-444.