-
1
-
-
0026010995
-
Molecular themes in oncogenesis
-
Bishop, J.M. Molecular themes in oncogenesis. Cell 1991, 64: 235-48.
-
(1991)
Cell
, vol.64
, pp. 235-248
-
-
Bishop, J.M.1
-
2
-
-
0026316096
-
Growth factors and cancer
-
Aaronson, S.A. Growth factors and cancer. Science 1991, 254: 1146-53.
-
(1991)
Science
, vol.254
, pp. 1146-1153
-
-
Aaronson, S.A.1
-
3
-
-
0025359146
-
Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues
-
Press, M.F., Cordon-Cardo, C., Slamon, D.J. Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues. Oncogene 1990, 5: 953-62.
-
(1990)
Oncogene
, vol.5
, pp. 953-962
-
-
Press, M.F.1
Cordon-Cardo, C.2
Slamon, D.J.3
-
4
-
-
33947733439
-
The role of the epidermal growth factor receptor and the c-erbB-2 protein in breast cancer
-
Gullick, W.J. The role of the epidermal growth factor receptor and the c-erbB-2 protein in breast cancer. Int J Cancer 1990, 5: 55-61.
-
(1990)
Int J Cancer
, vol.5
, pp. 55-61
-
-
Gullick, W.J.1
-
5
-
-
0022399581
-
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
-
Coussens, L., Yang-Feng, T.L., Liao, Y.C. et al. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 1985, 230: 1132-9.
-
(1985)
Science
, vol.230
, pp. 1132-1139
-
-
Coussens, L.1
Yang-Feng, T.L.2
Liao, Y.C.3
-
6
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon, D.J., Clark, G.M., Wong, S.G., Levin, W.J., Ullrich, A., McGuire, W.L. Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1981, 235: 177-82.
-
(1981)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
7
-
-
18244422222
-
HER-2/neu gene amplification characterized by fluorescence in situ hybridization: Poor prognosis in node-negative breast carcinomas
-
Press, M.F., Bernstein, L., Thomas, P.A. et al. HER-2/neu gene amplification characterized by fluorescence in situ hybridization: Poor prognosis in node-negative breast carcinomas. J Clin Oncol 1997, 15: 2894-904.
-
(1997)
J Clin Oncol
, vol.15
, pp. 2894-2904
-
-
Press, M.F.1
Bernstein, L.2
Thomas, P.A.3
-
8
-
-
0031684721
-
The HER-2/neu oncogene in breast cancer: Prognostic factor, predictive factor and target for therapy
-
Ross, J.S., Fletcher, J.A. The HER-2/neu oncogene in breast cancer: Prognostic factor, predictive factor and target for therapy. Oncologist 1998, 3: 237-52.
-
(1998)
Oncologist
, vol.3
, pp. 237-252
-
-
Ross, J.S.1
Fletcher, J.A.2
-
9
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon, D.J., Godolphin, W., Jones, L.A. et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 1989, 244: 707-12.
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
-
10
-
-
0023430930
-
Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH3T3 cell
-
Hudziak, R.M., Schlessinger, J., Ullrich, A. Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH3T3 cell. Proc Natl Acad Sci USA 1987, 84: 7159-63.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7159-7163
-
-
Hudziak, R.M.1
Schlessinger, J.2
Ullrich, A.3
-
11
-
-
0023196582
-
erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells
-
Di Fiore, P.P., Pierce, J.H., Kraus, M.H., Segatto, O., King, C.R., Aaronson, S.A. erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells. Science 1987, 237: 178-82.
-
(1987)
Science
, vol.237
, pp. 178-182
-
-
Di Fiore, P.P.1
Pierce, J.H.2
Kraus, M.H.3
Segatto, O.4
King, C.R.5
Aaronson, S.A.6
-
12
-
-
0022102126
-
Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies
-
Drebin, J.A., Link, V.C., Stern, D.F., Weinberg, R.A., Greene, M.I. Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies. Cell 1985, 41: 695-706.
-
(1985)
Cell
, vol.41
, pp. 695-706
-
-
Drebin, J.A.1
Link, V.C.2
Stern, D.F.3
Weinberg, R.A.4
Greene, M.I.5
-
13
-
-
3543024857
-
Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen
-
Drebin, J.A., Link, V.C., Weinberg, R.A., Greene, M.I. Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen. Proc Natl Acad Sci USA 1986, 83: 9129-33.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 9129-9133
-
-
Drebin, J.A.1
Link, V.C.2
Weinberg, R.A.3
Greene, M.I.4
-
14
-
-
0032127350
-
Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
-
Baselga, J., Norton, L., Albanell, J., Kim, Y.M., Mendelsohn, J. Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res 1998, 58: 2825-31.
-
(1998)
Cancer Res
, vol.58
, pp. 2825-2831
-
-
Baselga, J.1
Norton, L.2
Albanell, J.3
Kim, Y.M.4
Mendelsohn, J.5
-
15
-
-
0027375130
-
Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodies
-
Lewis, G.D., Figari, I., Fendly, B. et al. Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodies. Cancer Immunol Immunother 1993, 37: 255-63.
-
(1993)
Cancer Immunol Immunother
, vol.37
, pp. 255-263
-
-
Lewis, G.D.1
Figari, I.2
Fendly, B.3
-
16
-
-
0025804023
-
Monoclonal antibody therapy of human cancer: Taking the HER2 protooncogene to the clinic
-
Shepard, H.M., Lewis, G.D., Sarup, J.C. et al. Monoclonal antibody therapy of human cancer: Taking the HER2 protooncogene to the clinic. J Clin Immunol 1991, 11: 117-27.
-
(1991)
J Clin Immunol
, vol.11
, pp. 117-127
-
-
Shepard, H.M.1
Lewis, G.D.2
Sarup, J.C.3
-
17
-
-
0028670125
-
The biology of erbB-2/neu/HER-2 and its role in cancer
-
Hynes, N.E., Stern, D.F. The biology of erbB-2/neu/HER-2 and its role in cancer. Biochim Biophys Acta 1994, 1198: 165-84.
-
(1994)
Biochim Biophys Acta
, vol.1198
, pp. 165-184
-
-
Hynes, N.E.1
Stern, D.F.2
-
18
-
-
0022388402
-
The neu gene: An erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor
-
Schechter, A.L., Hung, M.C., Vaidyanathan, L. et al. The neu gene: An erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor. Science 1985, 229: 976-8.
-
(1985)
Science
, vol.229
, pp. 976-978
-
-
Schechter, A.L.1
Hung, M.C.2
Vaidyanathan, L.3
-
19
-
-
0030795612
-
The erbB signaling network in embryogenesis and oncogenesis: Signal diversification through combinatorial ligand-receptor interactions
-
Alroy, I., Yarden, Y. The erbB signaling network in embryogenesis and oncogenesis: Signal diversification through combinatorial ligand-receptor interactions. FEBS Lett 1997, 410: 83-6.
-
(1997)
FEBS Lett
, vol.410
, pp. 83-86
-
-
Alroy, I.1
Yarden, Y.2
-
20
-
-
2142843806
-
Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
-
Pinkas-Kramarski, R., Soussan, L., Waterman, H. et al. Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. EMBO J 1996, 15: 2452-67.
-
(1996)
EMBO J
, vol.15
, pp. 2452-2467
-
-
Pinkas-Kramarski, R.1
Soussan, L.2
Waterman, H.3
-
21
-
-
0028104202
-
Regulation of signal transduction and signal diversity by receptor oligomerization
-
Lemmon, M.A., Schlessinger, J. Regulation of signal transduction and signal diversity by receptor oligomerization. TIBS 1994, 19: 459-63.
-
(1994)
TIBS
, vol.19
, pp. 459-463
-
-
Lemmon, M.A.1
Schlessinger, J.2
-
22
-
-
0026360077
-
p185HER2 signal transduction in breast cancer cells
-
Scott, G.K., Dodson, J.M., Montgomery, P.A. et al. p185HER2 signal transduction in breast cancer cells. J Biol Chem 1991, 266: 14300-5.
-
(1991)
J Biol Chem
, vol.266
, pp. 14300-14305
-
-
Scott, G.K.1
Dodson, J.M.2
Montgomery, P.A.3
-
23
-
-
0023885771
-
Expression of oncogenes in thyroid tumors: Co-expression of c-erbB2/neu and c-erbB
-
Aasland, R., Lillehaug, J.R., Male, R., Josendal, O., Varhaug, J.E., Kleppe, K. Expression of oncogenes in thyroid tumors: Co-expression of c-erbB2/neu and c-erbB. Br J Cancer 1988, 57: 358-63.
-
(1988)
Br J Cancer
, vol.57
, pp. 358-363
-
-
Aasland, R.1
Lillehaug, J.R.2
Male, R.3
Josendal, O.4
Varhaug, J.E.5
Kleppe, K.6
-
24
-
-
0022486379
-
Amplification of c-erbB-2 oncogene in human adenocarcinomas in vivo
-
Yokota, J., Yamamoto, T., Toyoshima, K. et al. Amplification of c-erbB-2 oncogene in human adenocarcinomas in vivo. Lancet 1986, 1: 765-7.
-
(1986)
Lancet
, vol.1
, pp. 765-767
-
-
Yokota, J.1
Yamamoto, T.2
Toyoshima, K.3
-
25
-
-
0023187324
-
Overexpression of the c-erbB-2 oncoprotein in human breast carcinomas: Immunohistological assessment correlates with gene amplification
-
Venter, D.J., Tuzi, N.L., Kumar, S., Gullick, W.J. Overexpression of the c-erbB-2 oncoprotein in human breast carcinomas: Immunohistological assessment correlates with gene amplification. Lancet 1987, 2: 69-72.
-
(1987)
Lancet
, vol.2
, pp. 69-72
-
-
Venter, D.J.1
Tuzi, N.L.2
Kumar, S.3
Gullick, W.J.4
-
26
-
-
0029884715
-
Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescence in situ hybridization
-
Pauletti, G., Godolphin, W., Press, M.F., Slamon, D.J. Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescence in situ hybridization. Oncogene 1996, 13: 63-72.
-
(1996)
Oncogene
, vol.13
, pp. 63-72
-
-
Pauletti, G.1
Godolphin, W.2
Press, M.F.3
Slamon, D.J.4
-
27
-
-
0029814271
-
A hierarchical network of interreceptor interactions determines signal transduction by neu differentiation factor/neuregulin and epidermal growth factor
-
Tzahar, E., Waterman, H., Chen, X. et al. A hierarchical network of interreceptor interactions determines signal transduction by neu differentiation factor/neuregulin and epidermal growth factor. Mol Cell Biol 1996, 16: 5276-87.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5276-5287
-
-
Tzahar, E.1
Waterman, H.2
Chen, X.3
-
28
-
-
0026659262
-
Identification of heregulin, a specific activator of p185erbB2
-
Holmes, W.E., Sliwkowski, M.X., Akita, R.W. et al. Identification of heregulin, a specific activator of p185erbB2. Science 1992, 256: 1205-10.
-
(1992)
Science
, vol.256
, pp. 1205-1210
-
-
Holmes, W.E.1
Sliwkowski, M.X.2
Akita, R.W.3
-
29
-
-
0026555656
-
Characterization of a growth factor that binds exclusively to the erbB-2 receptor and induces cellular responses
-
Lupu, R., Colomer, R., Kannan, B., Lippman, M.E. Characterization of a growth factor that binds exclusively to the erbB-2 receptor and induces cellular responses. Proc Natl Acad Sci USA 1992, 89: 2287-91.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 2287-2291
-
-
Lupu, R.1
Colomer, R.2
Kannan, B.3
Lippman, M.E.4
-
30
-
-
0028358856
-
Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin
-
Sliwkowski, M.X., Schaefer, G., Akita, R.W. et al. Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin. J Biol Chem 1994, 269: 14661-5.
-
(1994)
J Biol Chem
, vol.269
, pp. 14661-14665
-
-
Sliwkowski, M.X.1
Schaefer, G.2
Akita, R.W.3
-
31
-
-
0030030072
-
ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: Implications for breast cancer
-
Karunagaran, D., Tzahar, E., Beerli, R.R. et al. ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: Implications for breast cancer. EMBO J 1996, 15: 254-64.
-
(1996)
EMBO J
, vol.15
, pp. 254-264
-
-
Karunagaran, D.1
Tzahar, E.2
Beerli, R.R.3
-
32
-
-
8944232866
-
Node-negative breast cancers with p53(-)/ HER2-neu(-) status may identify women with very good prognosis
-
Albanell, J., Bellmunt, J., Molina, R. et al. Node-negative breast cancers with p53(-)/ HER2-neu(-) status may identify women with very good prognosis. Anticancer Res 1996, 16: 1027-32.
-
(1996)
Anticancer Res
, vol.16
, pp. 1027-1032
-
-
Albanell, J.1
Bellmunt, J.2
Molina, R.3
-
33
-
-
0026472124
-
Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease
-
Guy, C.T., Webster, M.A., Schaller, M., Parsons, T.J., Cardiff, R.D., Muller, W.J. Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc Natl Acad Sci USA 1992, 89: 10578-82.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10578-10582
-
-
Guy, C.T.1
Webster, M.A.2
Schaller, M.3
Parsons, T.J.4
Cardiff, R.D.5
Muller, W.J.6
-
34
-
-
0025318271
-
Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product
-
Fendly, B.M., Winget, M., Hudziak, R.M., Lipari, M.T., Napier, M.A., Ullrich, A. Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product. Cancer Res 1990, 50: 1550-8.
-
(1990)
Cancer Res
, vol.50
, pp. 1550-1558
-
-
Fendly, B.M.1
Winget, M.2
Hudziak, R.M.3
Lipari, M.T.4
Napier, M.A.5
Ullrich, A.6
-
35
-
-
0024348697
-
Generation and characterization of monoclonal antibodies specific for the human neu oncogene product, p185
-
McKenzie, S.J., Marks, P.J., Lam, T. et al. Generation and characterization of monoclonal antibodies specific for the human neu oncogene product, p185. Oncogene 1989, 4: 543-8.
-
(1989)
Oncogene
, vol.4
, pp. 543-548
-
-
McKenzie, S.J.1
Marks, P.J.2
Lam, T.3
-
36
-
-
0026091927
-
Mechanistic aspects of the 23 opposing effects of monoclonal antibodies to the erbB-2 receptor on tumor growth
-
Stancovski, I., Hurwitz, E., Leitner, D., Ullrich, A., Yarden, Y., Sela, M. Mechanistic aspects of the 23 opposing effects of monoclonal antibodies to the erbB-2 receptor on tumor growth. Proc Natl Acad Sci USA 1991, 88: 8691-5.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 8691-8695
-
-
Stancovski, I.1
Hurwitz, E.2
Leitner, D.3
Ullrich, A.4
Yarden, Y.5
Sela, M.6
-
37
-
-
0026685034
-
Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies
-
Kasprzyk, P.G., Song, S.U., Di Fiore, P.P., King, C.R. Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies. Cancer Res 1992, 52: 2771-6.
-
(1992)
Cancer Res
, vol.52
, pp. 2771-2776
-
-
Kasprzyk, P.G.1
Song, S.U.2
Di Fiore, P.P.3
King, C.R.4
-
38
-
-
0025986825
-
A monoclonal antibody against the c-erbB-2 protein enhances the cytotoxicity of cis-diammine-dichloroplatinum against human breast and ovarian tumor cell lines
-
Hancock, M.C., Langton, B.C., Chan, T. et al. A monoclonal antibody against the c-erbB-2 protein enhances the cytotoxicity of cis-diammine-dichloroplatinum against human breast and ovarian tumor cell lines. Cancer Res 1991, 51: 4575-80.
-
(1991)
Cancer Res
, vol.51
, pp. 4575-4580
-
-
Hancock, M.C.1
Langton, B.C.2
Chan, T.3
-
39
-
-
0029879442
-
Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness
-
Lewis, G.D., Lofgren, J.A., McMurtrey, A.E. et al. Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness. Cancer Res 1996, 56: 1457-65.
-
(1996)
Cancer Res
, vol.56
, pp. 1457-1465
-
-
Lewis, G.D.1
Lofgren, J.A.2
McMurtrey, A.E.3
-
40
-
-
0024478054
-
p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor
-
Hudziak, R.M., Lewis, G.D., Winget, M., Fendly, B.M., Shepard, H.M., Ullrich, A. p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor. Mol Cell Biol 1989, 9: 1165-72.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1165-1172
-
-
Hudziak, R.M.1
Lewis, G.D.2
Winget, M.3
Fendly, B.M.4
Shepard, H.M.5
Ullrich, A.6
-
41
-
-
0027686394
-
Inhibition of human lung cancer cell line growth by an anti-p185HER2 antibody
-
Kern, J.A., Torney, L., Weiner, D., Gazdar, A., Shepard, H.M., Fendly, B. Inhibition of human lung cancer cell line growth by an anti-p185HER2 antibody. Am J Respir Cell Mol Biol 1993, 9: 448-54.
-
(1993)
Am J Respir Cell Mol Biol
, vol.9
, pp. 448-454
-
-
Kern, J.A.1
Torney, L.2
Weiner, D.3
Gazdar, A.4
Shepard, H.M.5
Fendly, B.6
-
42
-
-
0026610881
-
Humanization of an anti-p185HER2 antibody for human cancer therapy
-
Carter, P., Presta, L., Gorman, C.M. et al. Humanization of an anti-p185HER2 antibody for human cancer therapy. Proc Natl Acad Sci USA 1992, 89: 4285-9.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 4285-4289
-
-
Carter, P.1
Presta, L.2
Gorman, C.M.3
-
43
-
-
0000799256
-
Antibody dependent cell-mediated cytotoxicity in breast cancer patients in phase III clinical trials of a humanized anti-HER2 antibody
-
Pegram, M.D., Baly, D., Wirth, C. et al. Antibody dependent cell-mediated cytotoxicity in breast cancer patients in phase III clinical trials of a humanized anti-HER2 antibody. Proc Am Assoc Cancer Res 1997, 38: A4044.
-
(1997)
Proc Am Assoc Cancer Res
, vol.38
-
-
Pegram, M.D.1
Baly, D.2
Wirth, C.3
-
44
-
-
0000497857
-
Development and characterization of a rhuMAb HER2 antibody assay for clinical evaluation of cytotoxic potency
-
Baly, D.L., Wirth, C.M., Allison, D.A., Hotaling, T.E., Fox, J.A. Development and characterization of a rhuMAb HER2 antibody assay for clinical evaluation of cytotoxic potency. Proc Am Assoc Cancer Res 1997, 38: A181.
-
(1997)
Proc Am Assoc Cancer Res
, vol.38
-
-
Baly, D.L.1
Wirth, C.M.2
Allison, D.A.3
Hotaling, T.E.4
Fox, J.A.5
-
45
-
-
0029886350
-
In vitro and in vivo anti-tumor effects of a humanised monoclonal antibody against c-erbB-2 product
-
Tokuda, Y., Ohnishi, Y., Shimamura, K. et al. In vitro and in vivo anti-tumor effects of a humanised monoclonal antibody against c-erbB-2 product. Br J Cancer 1996, 73: 1362-5.
-
(1996)
Br J Cancer
, vol.73
, pp. 1362-1365
-
-
Tokuda, Y.1
Ohnishi, Y.2
Shimamura, K.3
-
46
-
-
0025968042
-
Regulation of phosphorylation of the c-erbB-2/ HER2 gene product by a monoclonal antibody and serum growth factor(s) in human mammary carcinoma cells
-
Kumar, R., Shepard, H.M., Mendelsohn, J. Regulation of phosphorylation of the c-erbB-2/ HER2 gene product by a monoclonal antibody and serum growth factor(s) in human mammary carcinoma cells. Mol Cell Biol 1991, 11: 979-86.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 979-986
-
-
Kumar, R.1
Shepard, H.M.2
Mendelsohn, J.3
-
47
-
-
0026174552
-
Characterization of an anti-p185HER2 monoclonal antibody that stimulates receptor function and inhibits tumor cell growth
-
Sarup, J.C., Johnson, R.M., King, K.L. et al. Characterization of an anti-p185HER2 monoclonal antibody that stimulates receptor function and inhibits tumor cell growth. Growth Regul 1991, 1: 72-82.
-
(1991)
Growth Regul
, vol.1
, pp. 72-82
-
-
Sarup, J.C.1
Johnson, R.M.2
King, K.L.3
-
48
-
-
0030959114
-
A subclass of tumor-inhibitory monoclonal antibodies to erbB-2/HER2 blocks crosstalk with growth factor receptors
-
Klapper, L.N., Vaisman, N., Hurwitz, E., Pinkas-Kramarski, R., Yarden, Y., Sela, M. A subclass of tumor-inhibitory monoclonal antibodies to erbB-2/HER2 blocks crosstalk with growth factor receptors. Oncogene 1997, 14: 2099-109.
-
(1997)
Oncogene
, vol.14
, pp. 2099-2109
-
-
Klapper, L.N.1
Vaisman, N.2
Hurwitz, E.3
Pinkas-Kramarski, R.4
Yarden, Y.5
Sela, M.6
-
49
-
-
0002168933
-
Effects of the 4D5 antibody on HER2/neu heterodimerization with other class I receptors in human breast cancer cells
-
Reese, D., Arboleda, J., Twaddell, J., Akita, R., Sliwkowski, M., Slamon, D. Effects of the 4D5 antibody on HER2/neu heterodimerization with other class I receptors in human breast cancer cells. Proc Am Assoc Cancer Res 1996, 37: A353.
-
(1996)
Proc Am Assoc Cancer Res
, vol.37
-
-
Reese, D.1
Arboleda, J.2
Twaddell, J.3
Akita, R.4
Sliwkowski, M.5
Slamon, D.6
-
50
-
-
0001223491
-
Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors
-
Petit, A.M., Rak, J., Hung, M.C. et al. Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors. Am J Pathol 1997, 151: 1523-30.
-
(1997)
Am J Pathol
, vol.151
, pp. 1523-1530
-
-
Petit, A.M.1
Rak, J.2
Hung, M.C.3
-
51
-
-
0027074588
-
Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu
-
Benz, C.C., Scott, G.K., Sarup, J.C. et al. Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu. Breast Cancer Res Treat 1992, 24: 85-95.
-
(1992)
Breast Cancer Res Treat
, vol.24
, pp. 85-95
-
-
Benz, C.C.1
Scott, G.K.2
Sarup, J.C.3
-
52
-
-
0027468645
-
A truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cells
-
Scott, G.K., Robles, R., Park, J.W. et al. A truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cells. Mol Cell Biol 1993, 13: 2247-57.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 2247-2257
-
-
Scott, G.K.1
Robles, R.2
Park, J.W.3
-
53
-
-
0026071364
-
The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells, SK-BR-3
-
Zabrecky, J.R., Lam, T., McKenzie, S.J., Carney, W. The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells, SK-BR-3. J Biol Chem 1991, 266: 1716-20.
-
(1991)
J Biol Chem
, vol.266
, pp. 1716-1720
-
-
Zabrecky, J.R.1
Lam, T.2
McKenzie, S.J.3
Carney, W.4
-
54
-
-
0025829608
-
A soluble protein related to the HER-2 proto-oncogene product is released from human breast carcinoma cells
-
Lin, Y.L., Clinton, G.M. A soluble protein related to the HER-2 proto-oncogene product is released from human breast carcinoma cells. Oncogene 1991, 6: 639-43.
-
(1991)
Oncogene
, vol.6
, pp. 639-643
-
-
Lin, Y.L.1
Clinton, G.M.2
-
55
-
-
0027524245
-
The extracellular domain of the c-erbB-2 oncoprotein is released from tumor cells by proteolytic cleavage
-
Pupa, S.M., Menard, S., Morelli, D., Pozzi, B., De Palo, G., Colnaghi, M. The extracellular domain of the c-erbB-2 oncoprotein is released from tumor cells by proteolytic cleavage. Oncogene 1993, 8: 2917-23.
-
(1993)
Oncogene
, vol.8
, pp. 2917-2923
-
-
Pupa, S.M.1
Menard, S.2
Morelli, D.3
Pozzi, B.4
De Palo, G.5
Colnaghi, M.6
-
56
-
-
0031564215
-
Soluble HER-2/neu neutralizes biologic effects of anti-HER-2/neu antibody on breast cancer cells in vitro
-
Brodowicz, T., Wiltschke, C., Budinsky, A.C., Krainer, M., Steger, G.G., Zielinski, C.C. Soluble HER-2/neu neutralizes biologic effects of anti-HER-2/neu antibody on breast cancer cells in vitro. Int J Cancer 1997, 73: 875-9.
-
(1997)
Int J Cancer
, vol.73
, pp. 875-879
-
-
Brodowicz, T.1
Wiltschke, C.2
Budinsky, A.C.3
Krainer, M.4
Steger, G.G.5
Zielinski, C.C.6
-
57
-
-
0029005754
-
Elevated serum c-erbB-2 antigen levels and decreased response to hormonal therapy of breast cancer
-
Leitzel, K., Teramoto, Y., Konrad, K. et al. Elevated serum c-erbB-2 antigen levels and decreased response to hormonal therapy of breast cancer. J Clin Oncol 1995, 13: 1129-235.
-
(1995)
J Clin Oncol
, vol.13
, pp. 1129-1235
-
-
Leitzel, K.1
Teramoto, Y.2
Konrad, K.3
-
58
-
-
0030757466
-
Prediction of response to antiestrogen therapy in advanced breast cancer patients by pretreatment circulating levels of extracellular domain of the HER-2/c-neu protein
-
Yamauchi, H., O'Neill, A., Gelman, R. et al. Prediction of response to antiestrogen therapy in advanced breast cancer patients by pretreatment circulating levels of extracellular domain of the HER-2/c-neu protein, J Clin Oncol 1996, 15: 18-25.
-
(1996)
J Clin Oncol
, vol.15
, pp. 18-25
-
-
Yamauchi, H.1
O'Neill, A.2
Gelman, R.3
-
59
-
-
0000908721
-
The role of ErbB2 extracellular domain in predicting response to chemotherapy in breast cancer patients
-
Harris, L.N., Trock, B., Berris, M. et al. The role of ErbB2 extracellular domain in predicting response to chemotherapy in breast cancer patients. Proc Am Soc Clin Oncol 1996, 15: A96.
-
(1996)
Proc Am Soc Clin Oncol
, vol.15
-
-
Harris, L.N.1
Trock, B.2
Berris, M.3
-
60
-
-
0029991439
-
Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
-
Baselga, J., Tripathy, D., Mendelsohn, J. et al. Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. J Clin Oncol 1996, 14:737-44.
-
(1996)
J Clin Oncol
, vol.14
, pp. 737-744
-
-
Baselga, J.1
Tripathy, D.2
Mendelsohn, J.3
-
61
-
-
0031903646
-
Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
-
Pegram, M.D., Lipton, A., Hayes, D.F. et al. Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J Clin Oncol 1998, 16: 2659-71.
-
(1998)
J Clin Oncol
, vol.16
, pp. 2659-2671
-
-
Pegram, M.D.1
Lipton, A.2
Hayes, D.F.3
-
62
-
-
0000905158
-
Efficacy and safety of Herceptin™ (humanized anti-HER2 antibody) as a single agent in 222 women with HER2 overexpression who relapsed following chemotherapy for metastatic breast cancer
-
Cobleigh, M.A., Vogel, C.L., Tripathy, D. et al. Efficacy and safety of Herceptin™ (humanized anti-HER2 antibody) as a single agent in 222 women with HER2 overexpression who relapsed following chemotherapy for metastatic breast cancer. Proc Am Soc Clin Oncol 1998, 17: A376.
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
-
63
-
-
0010316494
-
Antibodies against p185HER2 enhance etoposide induced cytotoxicity against human breast carcinoma cells
-
Arteaga, C.L., Carty-Dugger, T., Winnier, A.R. Antibodies against p185HER2 enhance etoposide induced cytotoxicity against human breast carcinoma cells. Proc Am Soc Clin Oncol 1993, 12: A103.
-
(1993)
Proc Am Soc Clin Oncol
, vol.12
-
-
Arteaga, C.L.1
Carty-Dugger, T.2
Winnier, A.R.3
-
64
-
-
0032578797
-
Remission of human breast cancer xenografts on therapy with humanized monoclonal antibody to HER-2 receptor and DNA-reactive drugs
-
Pietras, R.J., Pegrani, M.D., Finn, R.S., Maneval, D.A., Slamon, D.J. Remission of human breast cancer xenografts on therapy with humanized monoclonal antibody to HER-2 receptor and DNA-reactive drugs. Oncogene 1998, 17: 2235-49.
-
(1998)
Oncogene
, vol.17
, pp. 2235-2249
-
-
Pietras, R.J.1
Pegrani, M.D.2
Finn, R.S.3
Maneval, D.A.4
Slamon, D.J.5
-
65
-
-
0028200221
-
Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells
-
Pietras, R.J., Fendly, B.M., Chazin, V.R., Pegram, M.D., Howell, S.D., Slamon, D.J. Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells. Oncogene 1994, 9: 1829-38.
-
(1994)
Oncogene
, vol.9
, pp. 1829-1838
-
-
Pietras, R.J.1
Fendly, B.M.2
Chazin, V.R.3
Pegram, M.D.4
Howell, S.D.5
Slamon, D.J.6
-
66
-
-
0028167813
-
p185c-erbB-2 signal enhances cisplatin-induced cytotoxicity in human breast carcinoma cells: Association between an oncogenic receptor tyrosine kinase and drug-induced DNA repair
-
Arteaga, C.L., Winnier, A.R., Poirier, M.C. et al. p185c-erbB-2 signal enhances cisplatin-induced cytotoxicity in human breast carcinoma cells: Association between an oncogenic receptor tyrosine kinase and drug-induced DNA repair. Cancer Res 1994, 54: 3758-65.
-
(1994)
Cancer Res
, vol.54
, pp. 3758-3765
-
-
Arteaga, C.L.1
Winnier, A.R.2
Poirier, M.C.3
-
67
-
-
0029981617
-
Chemotherapy for advanced breast cancer: A current perspective
-
Seidman, A.D. Chemotherapy for advanced breast cancer: A current perspective. Semin Oncol 1996, 23: 55-9.
-
(1996)
Semin Oncol
, vol.23
, pp. 55-59
-
-
Seidman, A.D.1
-
68
-
-
0000593691
-
Malignant tumors of the breast
-
DeVita, V.T. (Ed.). Lippincott-Raven: Philadelphia
-
Harris, J.R., Morrow, M., Norton, L. Malignant tumors of the breast. In: Cancer: Principles & Practice of Oncology, 5th Ed. DeVita, V.T. (Ed.). Lippincott-Raven: Philadelphia 1997, 1557-616.
-
(1997)
Cancer: Principles & Practice of Oncology, 5th Ed.
, pp. 1557-1616
-
-
Harris, J.R.1
Morrow, M.2
Norton, L.3
-
69
-
-
0001687355
-
Antitumor activity of paclitaxel in combination with anti-growth factor receptor monoclonal antibodies in breast cancer xenografts
-
Baselga, J., Norton, L., Coplan, K., Shalaby, R., Mendelsohn, J. Antitumor activity of paclitaxel in combination with anti-growth factor receptor monoclonal antibodies in breast cancer xenografts. Proc Am Assoc Cancer Res 1994, 35: A2262.
-
(1994)
Proc Am Assoc Cancer Res
, vol.35
-
-
Baselga, J.1
Norton, L.2
Coplan, K.3
Shalaby, R.4
Mendelsohn, J.5
-
70
-
-
0027290650
-
Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies
-
Baselga, J., Norton, L., Masui, H. et al. Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies. J Natl Cancer Inst 1993, 85: 1327-33.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1327-1333
-
-
Baselga, J.1
Norton, L.2
Masui, H.3
-
71
-
-
0000566280
-
Phase I studies of anti-epidermal growth factor receptor (EGFR) chimeric monoclonal antibody C225 in patients with EGFR overexpressing tumors
-
Bos, M., Mendelsohn, J., Bowden, D. et al. Phase I studies of anti-epidermal growth factor receptor (EGFR) chimeric monoclonal antibody C225 in patients with EGFR overexpressing tumors. Proc Am Soc Clin Oncol 1996, 15: A443.
-
(1996)
Proc Am Soc Clin Oncol
, vol.15
-
-
Bos, M.1
Mendelsohn, J.2
Bowden, D.3
-
72
-
-
0030880078
-
Chemosensitization of HER-2/neu-overexpressing human breast cancer cells to paclitaxel (Taxol) by adenovirus type 5 E1A
-
Ueno, N.T., Yu, D., Hung, M.C. Chemosensitization of HER-2/neu-overexpressing human breast cancer cells to paclitaxel (Taxol) by adenovirus type 5 E1A. Oncogene 1997, 15: 953-60.
-
(1997)
Oncogene
, vol.15
, pp. 953-960
-
-
Ueno, N.T.1
Yu, D.2
Hung, M.C.3
-
73
-
-
0030067015
-
Sensitization of HER-2/ neu-overexpressing non-small cell lung cancer cells to chemotherapeutic drugs by tyrosine kinase inhibitor emodin
-
Zhang, L., Hung, M.C. Sensitization of HER-2/ neu-overexpressing non-small cell lung cancer cells to chemotherapeutic drugs by tyrosine kinase inhibitor emodin. Oncogene 1996, 12: 571-6.
-
(1996)
Oncogene
, vol.12
, pp. 571-576
-
-
Zhang, L.1
Hung, M.C.2
-
77
-
-
0000405942
-
Addition of Herceptin™ (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer (HER2+/MBC) markedly increases anticancer activity: A randomized, multinational controlled phase III trial
-
Slamon, D., Leyland-Jones, B., Shak, S. et al. Addition of Herceptin™ (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer (HER2+/MBC) markedly increases anticancer activity: A randomized, multinational controlled phase III trial. Proc Am Soc Clin Oncol 1998, 17: A377.
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Slamon, D.1
Leyland-Jones, B.2
Shak, S.3
-
78
-
-
0001876216
-
Efficacy and safety of Herceptin (trastuzumab, humanized anti-HER2 antibody) as a single agent in first line treatment of HER2 overexpressing metastatic breast cancer (HER2+/ MBC)
-
Vogel, C.L., Cobleigh, M.A., Tripathy, D. et al. Efficacy and safety of Herceptin (trastuzumab, humanized anti-HER2 antibody) as a single agent in first line treatment of HER2 overexpressing metastatic breast cancer (HER2+/ MBC). Breast Cancer Res Treat 1998, 50: A23.
-
(1998)
Breast Cancer Res Treat
, vol.50
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
-
79
-
-
0031757277
-
Dose-dense therapy with weekly 1-hour paclitaxel infusions in the treatment of metastatic breast cancer
-
Seidman, A.D., Hudis, C.A., Albanell, J. et al. Dose-dense therapy with weekly 1-hour paclitaxel infusions in the treatment of metastatic breast cancer. J Clin Oncol 1998, 16: 3353-61.
-
(1998)
J Clin Oncol
, vol.16
, pp. 3353-3361
-
-
Seidman, A.D.1
Hudis, C.A.2
Albanell, J.3
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