Modeling the probability that Ashkenazi Jewish women carry a founder mutation in BRCA1 or BRCA2 [1] (multiple letters)

American Journal of Human Genetics

Volumn 65, Issue 6, 1999, Pages 1771-1775

  Hopper, J L ^a   Jenkins, M A ^a   Wacholder, S ^a   Hartge, P ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; CANCER RISK; FAMILY HISTORY; FEMALE; FOUNDER EFFECT; GENE MUTATION; GENETIC RISK; HETEROZYGOTE DETECTION; HUMAN; JEW; LETTER; ONCOGENE; POPULATION RESEARCH; PREVALENCE; PRIORITY JOURNAL; PROBABILITY;

EID: 0033362079     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/302674     Document Type: Letter

References (9)

1. D Abeliovich L Kaduri I Lerer N Weinberg G Amir M Sagi J Zlotogora The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women Am J Hum Genet 60 1997 505 514
2. RJ Baker JA Nelder The GLIM system, release 3: generalized linear interactive modelling 1978 Numerical Algorithms Group Oxford
3. FJ Couch ML DeShano MA Blackwood K Calzone J Stopfer L Campeau A Ganguly BRCA1 mutation in women attending clinics that evaluate the risk of breast cancer N Engl J Med 336 1997 1409 1415
4. P Hartge JP Struewing S Wacholder LC Brody MA Tucker The prevalence of common BRCA1 and BRCA2 mutations among Ashkenazi Jews Am J Hum Genet 64 1999 963 970
5. JL Hopper MC Southey GS Dite DJ Jolley GG Giles MRE McCredie DF Easton Australian Breast Cancer Family Study Population-based estimate of the average age-specific cumulative risk of breast cancer for a defined set of protein-truncating mutations in BRCA1 and BRCA2 Cancer Epidemiol Biomarker Prevent 8 1999 741 747
6. P McCullagh JA Nelder Generalized linear models 1983 Chapman & Hall London
7. J Peto N Collins R Barfoot S Seal W Warren N Rahman DF Easton Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer J Natl Cancer Inst 91 1999 943 949
8. D Shattuck-Eidens A Oliphant M McClure C McBride J Gupte T Rubano D Pruss BRCA1 sequence analysis in women at high risk for susceptibility mutations: risk factor analysis and implications for genetic testing JAMA 278 1997 1242 1250
9. JP Struewing P Hartge S Wacholder SM Baker M Berlin M McAdams MM Timmerman The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews N Engl J Med 336 1997 1401 1408