CCAAT/enhancer-binding protein α is a physiological regulator of prolactin gene expression

Endocrinology

Volumn 140, Issue 10, 1999, Pages 4542-4550

  Jacob, K K ^a   Stanley, F M ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NUCLEAR PROTEIN; PROLACTIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENE MUTATION; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING;

EID: 0033305603     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.10.7076     Document Type: Article

References (38)

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3. Tissue specific trans-acting factor interaction with proximal rat prolactin gene promoter sequences
4. Visualization of Pit-1 transcription factor interaction in the living cell nucleus by fluorescence resonance energy transfer microscopy
5. The insulin and cAMP response elements of the prolactin gene are overlapping sequences
6. Binding of a 100 kDa ubiquitous factor to the human prolactin promoter is required for its basal and hormone-regulated activity
7. Identification of an estrogen-responsive element from the 5'-flanking region of the rat prolactin gene
8. Both Pit-1 and the estrogen receptor are required for estrogen responsiveness of the rat prolactin gene
9. A composite Ets/Pit-1 binding site in the prolactin gene can mediate transcriptional responses to multiple signal transduction pathways
10. GHF-1/Pit-1 functions as a cell-specific integrator of Ras signaling by targeting the Ras pathway to a composite Ets-1/GHF-1 response element
11. The EGF response element of the prolactin promoter
12. Characterization of a nontissue-specific, 3',5'-cyclic adenosine monophosphate-responsive element in the proximal region of the rat prolactin gene
13. Transcriptional induction of the human prolactin gene by cAMP requires two cis-acting elements and at least the pituitary-specific factor Pit-1
14. A consensus insulin response element of the prolactin, somatostatin, and thymidine kinase genes is ets-factor activated
15. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells
16. Relative roles of CCAAT/enhancer-binding protein β and cAMP regulatory element-binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase (GTP)
17. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant negative inhibitor of gene transcription
18. Signaling pathways through which insulin regulates CAAT/enhancer binding protein α (C/EBPα) phosphorylation and gene expression in 3T3-L1 adipocytes
19. Induction of the mouse serum amyloid A3 gene by cytokines requires both C/EBP family proteins and a novel constitutive nuclear factor
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21. Stimulation of prolactin gene expression by insulin
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23. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
24. Tissue-specific in vitro transcription from the mouse albumin promoter
25. Identification and analysis of all components of a gel retardation assay by combination with immunoblotting
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27. An element in the prolactin promoter mediates the stimulation of insulin on transcription of the prolactin gene
28. Molecular characterization of transcription factors that bind to the cAMP responsive region of the substance P precursor gene. cDNA cloning of a novel C/EBP related factor
29. C/EBP, NF-κB, and c-Ets family members and transcriptional regulation of the cell-specific and inducible macrophage inflammatory protein 1α immediate-early gene
30. GABP mediates insulin-increased prolactin gene transcription
31. CCAAT/Enhancer-binding protein a activation of the rat growth hormone promoter in pituitary progenitor GHFT1-5 cells
32. Cyclic Adenosine 3',5'-monophosphate activation of the rat prolactin promoter is restricted to the pituitary-specific cell type
33. Reconstitution of protein kinase A regulation of the rat prolactin promoter in HeLa nonpituitary cells: Identification of both GHF-1/Pit-1-dependent and -independent mechanisms
34. CCAAT/enhancer binding protein activates the promoter of the serum albumin gone in cultured hepatoma cells
35. DNA-binding specificity of the PAR basic leucine zipper protein VBP partially overlaps those of the C/EBP and CREB/ATF families and is influenced by domains that flank the core basic region
36. Impaired cyclic AMP-dependent phosphorylation renders CREB a repressor of C/EBP-induced transcription of the somatostatin gene in an insulinoma cell line
37. The roles of the CCAAT/enhancer-binding protein in the transcriptional regulation of the gene for phosphoenolpyruvate carboxykinase (GTP)
38. Insulin inhibits liver expression of the CCAAT/erthancer-binding protein β