The EGF response element in the prolactin promoter

Molecular and Cellular Endocrinology

Volumn 152, Issue 1-2, 1999, Pages 137-145

  Jacob, Kirsten K ^a   Wininger, Eric ^a   Diminni, Kimberly ^a   Stanley, Frederick M ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

cAMP; EGF; Ets; Insulin; Prolactin; Transcription

Indexed keywords

EPIDERMAL GROWTH FACTOR; INSULIN; PROLACTIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; CYCLIC AMP; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION REGULATION; HYPOGLYCEMIC AGENTS; INSULIN; MOLECULAR SEQUENCE DATA; PROLACTIN; PROMOTER REGIONS (GENETICS); RATS; TRANSCRIPTION, GENETIC;

EID: 0033603561     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(99)00043-X     Document Type: Article

References (34)

1. Bradford A.P., Conrad K.E., Wasylyk C., Wasylyk B., Gutierrez Hartmann A. Functional interaction of cEts-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: mapping of the essential c-Ets-1 domain. Mol. Cell. Biol. 15:1995;2849-2857.
2. Bradford A.P., Conrad K.E., Tran P.H., Ostrowski M.C., Gutierrez Hartmann A. GHF-1/Pit-1 functions as a cell-specific integrator of Ras signaling by targeting the Ras pathway to a composite Ets-1/GHF-1 response element. J. Biol. Chem. 271:1996;24639-24648.
3. Castrillo J.-L., Bodner M., Karin M. Purification of growth hormone-specific transcription factor GHF-1 containing homeobox. Science. 243:1989;814-817.
4. Conrad K.E., Oberwetter J.M., Vaillancourt R., Johnson G.L., Gutierrez-Hartmann A. Identification of the functional components of the Ras signaling pathway regulating pituitary cell-specific gene expression. Mol. Cell. Biol. 14:1994;1553-1565.
5. Day R.N., Aalder J.A., Maurer R.A. A protein kinase inhibitor gene reduces both basal and multihormone-stimulated prolactin gene transcription. J. Biol. Chem. 264:1989;431-436.
6. Elsholtz H.P., Mangalam H.J., Potter E., Albert V.R., Supowit S., Evans R.M., Rosenfeld M.G. Two different cis-active elements transfer the transcriptional effects of both EGF and phorbol esters. Science. 234:1986;1552-1557.
7. Fox S.R., Jong M.T.C., Casanova J., Ye Z.-S., Stanley F., Samuels H.H. The homeodomain protein, Pit-1/GHF-1, is capable of binding to and activating both the growth hormone and prolactin gene promoters. Mol. Endocrinol. 4:1990;1069-1080.
8. Giese K., Cox J., Grosschedl R. The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures. Cell. 69:1992;185-196.
9. Han T.H., Lamph W.W., Prywes R. Mapping of Epidermal Growth Factor-, serum, and phorbol ester-responsive sequence elements in the c jun promoter. Mol. Cell. Biol. 12:1992;4472-4477.
10. Hill C.S., Marais R., John S., Wynne J., Dalton S., Treisman R. Functional analysis of a growth factor-responsive transcription factor complex. Cell. 73:1993;395-406.
11. Howard P.W., Maurer R.A. A composite Ets/Pit-1 binding site in the prolactin gene can mediate transcriptional responses to multiple signal transduction pathways. J. Biol. Chem. 270:1995;20930-20936.
12. Jacob K.K., Stanley F.M. The insulin and cAMP response elements of the prolactin gene are overlapping sequences. J. Biol. Chem. 269:1994;515-525.
13. Jacob K.K., Stanley F.M. Insulin and cAMP stimulation of prolactin gene transcription is through different mechanisms. Mol. Cell. Endocrinol. 109:1995;175-181.
14. Jacob K.K., Ouyang L., Stanley F.M. A consensus insulin response element of the prolactin, somatostatin, and thymidine dinase genes is ets-factor activated. J. Biol. Chem. 270:1995;27773-27779.
15. Jacob K.K., Sap J., Stanley F.M. RPTPα specifically inactivates insulin signaling to prolactin gene expression. J. Biol. Chem. 273:1998;4800-4809.
16. Kaise M., Muraoka A., Yamada J., Yamada T. Epidermal growth factor induces H+, K+-ATPase α-subunit gene expression through an element homologous to the 3′ half site of the c-Fos serum response element. J. Biol. Chem. 270:1995;18637-18642.
17. Langer S.J., Bortner D.M.F.T., Sherr C.J., Ostrowski M.C. Mitogenic signaling by colony stimulating factor 1 and ras is suppressed by the ets 2 DNA-binding domain and restored by myc overexpression. Mol. Cell. Biol. 12:1992;5355-5362.
18. Liang J., Kim K.E., Schoderbek W.E., Maurer R.A. Characterization of a non/issue-specific, 3′, 5′ -cyclic adenosine monophosphate responsive element in the proximal region of the rat prolactin gene. Mol. Endocrinol. 6:1992;885-892.
19. Mangalam H.J., Albert V.R., Ingraham H.A., Kapiloff M., Wilson L., Nelson C., Elsholtz H., Rosenfeld M.G. A pituitary POU domain protein, Pit-1, activates both growth hormone and prolactin promoters transcriptionally. Genes Dev. 3:1989;946-958.
20. Merchant J.L., Shiotani A., Mortensen E.R., Shumaker D.K., Abraczinskas D.R. Epidermal growth factor stimulation of the human gastrin promoter requires Sp1. J. Biol. Chem. 270:1995;6314-6319.
21. Murdoch G.H., Potter E., Nicolaisen A.K., Evans R.M., Rosenfeld M.G. Epidermal growth factor rapidly stimulates prolactin gene transcription. Nature. 300:1982;192-194.
22. Nilsson M., Toftgard R., Bohm S. Activated Ha-Ras but not TPA induces transcription through binding sites for activating transcription factor 3/Jun and a novel nuclear factor. J. Biol. Chem. 270:1995;12210-12218.
23. Ouyang L., Jacob K.K., Stanley F.M. GABP mediates insulin increased prolactin gene transcription. J. Biol. Chem. 271:1996;10425-10428.
24. Peers B., Nalda A.M., Monget P., Voz M.L., Belayew A., Martial J.A. Binding of a 100 kDa ubiquitous factor to the human prolactin promoter is required for its basal and hormone-regulated activity. Eur. J. Biochem. 210:1992;53-58.
25. Pestell R.G., Albanese C., Watanabe G., Lee R.J., Lastiowiecki P., Zon L., Ostrowski M., Jameson J.L. Stimulation of the P-450 side chain cleavage enzyme (CYP11 A1) promoter through ras- and Ets-2-signaling pathways. Mol. Endocrinol. 10:1996;1084-1094.
26. Pickett C.A., Gutierrez-Hartmann A. Epidermal Growth factor and Ras regulate gene expression in GH4 pituitary cells by separate, antagonistic signal transduction pathways. Mol. Cell. Biol. 15:1995;6777-6784.
27. Ren Y., Satoh T., Yamada M., Hashimoto K., Konaka S., Iwasaki T., Mori M. Stimulation of the preprothyrotropin-releasing hormone gene by epidermal growth factor. Endocrinology. 139:1998;195-203.
28. Ruff-Jamison S., Chen K., Cohen S. Epidermal growth factor induces the tyrosine phosphorylation and nuclear translocation of Stat 5 in mouse liver. Proc. Natl. Acad. Sci. USA. 92:1995;4215-4218.
29. Shi H., Teng C. Promoter-specific activation of mouse lactoferrin gene by epidermal growth factor involves two adjacent regulatory elements. Mol. Endocrinol. 10:1996;732-741.
30. Stanley F.M. Stimulation of prolactin gene expression by insulin. J. Biol. Chem. 263(13):1988;444-448.
31. Stanley F.M. An element in the prolactin promoter mediates the stimulation of insulin on transcription of the prolactin gene. J. Biol. Chem. 267:1992;16719-16726.
32. Thanos D., Maniatis T. High mobility group protein HMG l(Y) is required for NF-κB dependent virus induction of the human IFN-β gene. Cell. 71:1992;777-789.
33. Umesono K., Evans R.M. Determinants of target gene specificity for steroid/thyroid hormone receptors. Cell. 57:1989;1139-1146.
34. Whittaker J., Okamoto A.K., Thys R., Bell G.I., Steiner D.F., Hoffman A.R. High-level expression of human insulin receptor cDNA in mouse NIH 3T3 cells. Proc. Natl. Acad. Sci. USA. 84:1987;5237-5241.