HMC-1 mast cells activate human orbital fibroblasts in coculture: Evidence for up-regulation of prostaglandin E2 and hyaluronan synthesis

Endocrinology

Volumn 140, Issue 8, 1999, Pages 3518-3525

  Smith, Terry J ^a,b   Parikh, Sonia J ^a  

^a STRATTON VA MEDICAL CENTER   (United States)

^b ALBANY MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYALURONIC ACID; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE;

ARTICLE; CELL INTERACTION; COCULTURE; ENDOCRINE OPHTHALMOPATHY; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; MAST CELL; ORBIT; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0033305039     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.8.6881     Document Type: Article

References (57)

1. Connective tissue, glycosaminoglycans, and diseases of the thyroid
2. Immunohistochemical and ultrastructural studies on the exenterated orbital tissues of a patient with Graves' disease
3. Cytolitic T cells with Th1-like cytokine profile predominate in retroorbital lymphocytic infiltrates of Graves' ophthalmopathy
4. Retrobulbar T cells from patients with Graves' ophthalmopathy are CD8' and specifically recognize autologous fibroblasts
5. Molecular cloning and characterization of genes for antibodies generated by orbital tissue-infiltrating B-cells in Graves' ophthalmopathy
6. Influence of thyrotrophic hormone on connective tissue. Pathogenetic significance of mucopolysaccharides in experimental exophthalmos
7. The origin of synovial mucin: Erlich's mast cell-a secretory element of the connective tissue
8. Human mast cells augment fibroblast proliferation by heterotypic cell-cell adhesion and action of IL-4
9. Mast cells induce T-cell adhesion to human fibroblasts bv regulating intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 expression
10. Fibroblasts as sentinel cells: Synthesis of chemokines and regulation of inflammation
11. Evidence for cellular heterogeneity in primary cultures of human orbital fibroblasts
12. Human orbital fibroblasts in culture bind and respond to endothelin
13. Hormonal regulation of hyaluronate synthesis in cultured human fibroblasts: Evidence for differences between retroocular and dermal fibroblasts
14. Dexamethasone regulation of glycosaminoglycan synthesis in cultured human skin fibroblasts: Similar effects of glucocorticoid and thyroid hormones
15. Regulation of glycosaminoglycan synthesis by thyroid hormone in vitro
16. Interferon-γ is an inducer of plasminogen activator inhibitor type 1 in human orbital fibroblasts
17. Interferon gamma regulation of de novo protein synthesis in human dermal fibroblasts in culture is anatomic site dependent
18. Leukoregulin induction of protein expression in human orbital fibroblasts: Evidence for anatomical site-restricted cytokine-target cell interactions
19. Human orbital fibroblasts in culture express ganglioside profiles distinct from those in dermal fibroblasts
20. Human thyroid fibroblasts exhibit a distinctive phenotype in culture: Characteristic ganglioside profile and functional CD40 expression
21. Leukoregulin is a potent inducer of hyaluronan synthesis in cultured human orbital fibroblasts
22. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2
23. Cyclooxygenases as the principal targets for the actions of NSAIDs
24. Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment
25. Molecular characterization of the 5.2 KB isoform of the human cyclooxygenase-1 transcript
26. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
27. Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene
28. cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase
29. A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein
30. Leukoregulin induction of prostaglandin-endoperoxide H synthase-2 in human orbital fibroblasts
31. Establishment of an immature mast cell line from a patient with mast cell leukemia
32. n-Butyrate inhibition of hyaluronate synthesis in cultured human fibroblasts
33. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
34. The effect of thyroid hormone on glycosaminoglycan accumulation in human skin fibroblasts
35. Induction of cyclooxygenase-2 by interleukin-1α. Evidence for post-transcriptional regulation
36. Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes
37. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
38. Expression and regulation of hyaluronan synthase (HS) mRNAs in primary human fibroblasts: Potential insights into diseases of the thyroid
39. Leukoregulin induces plasminogen activator inhibitor type 1 in human orbital fibroblasts
40. Pleiotropic action of interferon gamma in human orbital flbroblasts
41. 2 elicits a morphological change in cultured orbital fibroblasts from patients with Graves ophthalmopathy
42. 2 alters human orbital fibroblast shape through a mechanism involving the generation of cyclic adenosine monophosphate
43. Stimulation of glycosaminoglycan accumulation by interferon gamma in cultured human retroocular fibroblasts
44. Increased induction of HLA-DR by interferon-γ in cultured fibroblasts derived from patients with Graves' ophthalmopathy and pretibial dermopathy
45. Tryptase, a mast cell serine protease
46. Mast cell tryptase is a mitogen for cultured fibroblasts
47. Human mast cells activate fibroblasts. Tryptase is a fibrogenic factor stimulating collagen messenger ribonucleic acid synthesis and fibroblast chemotaxis
48. Reaction of mast cell proteases tryptase and chymase with protease activated receptors (PARs) on keratinocytes and fibroblasts
49. A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells
50. Human orbital fibroblasts are activated through CD40 to induce proinflammatory cytokine production
51. Activation of human orbital fibroblasts through CD40 engagement results in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression: Insights into potential pathogenic mechanisms of thyroid-associated ophthalmopathy
52. 2 production in human lung fibroblasts
53. Functional cloning of the cDNA for a human hyaluronan synthase
54. Molecular identification of a putative human hyaluronan synthase
55. Molecular cloning and characterization of a cDNA encoding the third putative mammalian hyaluronan synthase
56. Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family
57. Molecular cloning and characterization of the human and mouse UDP-glucose dehydrogenase genes