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Volumn 1, Issue 4-5, 1999, Pages 231-247

Cholinergic muscarinic receptor signaling by the phosphoinositide signal transduction system in Alzheimer's disease

Author keywords

Acetylcholine; G protein; Postmortem; Protein kinase; amyloid

Indexed keywords

CHOLINERGIC RECEPTOR STIMULATING AGENT; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; MUSCARINIC RECEPTOR; PRESYNAPTIC RECEPTOR;

EID: 0033302310     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-1999-14-505     Document Type: Review
Times cited : (10)

References (83)
  • 3
    • 0027426832 scopus 로고
    • Metabolic alterations common to neural and non-neural cells in Alzheimer's disease
    • (1993) Hippocampus , vol.3 , pp. 45-54
    • Blass, J.P.1
  • 9
    • 0029379605 scopus 로고
    • Processing of the β-amyloid precursor protein and its regulation in Alzheimer's disease
    • (1995) J Neurochem , vol.65 , pp. 1431-1444
    • Checler, F.1
  • 13
    • 0024389272 scopus 로고
    • Carbachol and histamine stimulation of guanine-nucleotide-dependent phosphoinositide hydrolysis in rat brain cortical membranes
    • (1989) Biochem J , vol.261 , pp. 29-35
    • Claro, E.1    Garcia, A.2    Picatoste, F.3
  • 14
    • 0024462312 scopus 로고
    • Carbachol in the presence of guanosine 5'-O-(3-thiotriphosphate) stimulates the breakdown of exogenous phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol by rat brain membranes
    • (1989) J Biol Chem , vol.264 , pp. 18288-18295
    • Claro, E.1    Wallace, M.A.2    Lee, H.M.3    Fain, J.N.4
  • 17
    • 0028989045 scopus 로고
    • β-Amyloid peptides enhance binding of the calcium mobilising second messengers, inositol-(1,4,5)trisphosphate and inositol (1,3,4,5)-tetrakisphosphate to their receptor sites in rat cortical membranes
    • (1995) Neurosci Lett , vol.191 , pp. 31-34
    • Cowburn, R.F.1    Wiehager, B.2    Sundstrom, E.3
  • 19
    • 0027984082 scopus 로고
    • Amyloid β protein disruption of cholinergic and growth factor phospholipase C signals could underlie cognitive and neurodegenerative aspects of Alzheimer's disease
    • (1994) Neurobiol Aging , vol.15
    • Crews, F.T.1
  • 26
    • 0025969654 scopus 로고
    • Loss of high-affinity agonist binding to M1 muscarinic receptors in Alzheimer's disease: Implications for the failure of cholinergic replacement therapies
    • (1991) Ann Neurol , vol.29 , pp. 256-262
    • Flynn, D.D.1    Weinstein, D.A.2    Mash, D.C.3
  • 30
    • 0028981972 scopus 로고
    • Phosphoinositide hydrolysis, Gαq, phospholipase C, and protein kinase C in post mortem human brain: Effects of post mortem interval, subject age, and Alzheimer's disease
    • (1995) Neuroscience , vol.69 , pp. 125-138
    • Greenwood, A.F.1    Powers, R.E.2    Jope, R.S.3
  • 36
    • 0028172796 scopus 로고
    • 3H]PtdIns hydrolysis in postmortem human brain membranes is mediated by the G-proteins Gq/11 and phospholipase C-β
    • (1994) Biochem J , vol.304 , pp. 655-659
    • Jope, R.S.1    Song, L.2    Powers, R.3
  • 42
    • 0026583147 scopus 로고
    • Adrenalectomy increases phosphoinositide hydrolysis induced by norepinephrine or excitatory amino acids in rat hippocampal slices
    • (1992) Brain Res , vol.579 , pp. 128-134
    • Kolasa, K.1    Song, L.2    Jope, R.S.3
  • 46
    • 0024371616 scopus 로고
    • Interaction of cerebral-cortical membranes with exogenously added phosphatidylinositol 4,5-bisphosphate
    • (1989) Biochem J , vol.261 , pp. 325-331
    • Litosch, I.1
  • 56
    • 0027450994 scopus 로고
    • Alterations of signal transduction in the lesioned entorhinal-hippocampal system: A minireview on Alzheimer's disease-related changes and experimental data
    • (1993) Hippocampus , vol.3 , pp. 131-138
    • Ohm, T.G.1
  • 64
    • 0027934665 scopus 로고
    • Tubulin-G protein association stabilizes GTP binding and activates GTPase: Cytoskeletal participation in neuronal signal transduction
    • (1994) Biochemistry , vol.33 , pp. 9800-9805
    • Roychowdhury, S.1    Rasenick, M.M.2
  • 79
    • 0028148893 scopus 로고
    • Effects of Alzheimer's disease-related β amyloid protein fragments on enzymes metabolizing phosphoinositides in brain
    • (1994) Biochim Biophys Acta , vol.1227 , pp. 183-187
    • Wallace, M.A.1
  • 80
    • 0028304198 scopus 로고
    • Receptor-mediated activation of G proteins is reduced in postmortem brains from Alzheimer's disease patients
    • (1994) Neurosci Lett , vol.173 , pp. 37-39
    • Wang, H.-Y.1    Friedman, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.