Physiological levels of substrate deformation are less stimulatory to bone cells compared to fluid flow

American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

Volumn 43, Issue , 1999, Pages 161-162

  You, Jun ^a   Yellowley, Clare E ^a   Donahue, Henry J ^a   Jacobs, Christopher R ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMECHANICS; BONE; CELL IMMOBILIZATION; KINEMATICS; PHYSIOLOGY;

CYSTOLIC CALCIUM MOBILIZATION; LOAD INDUCED SIGNAL;

CELLS;

EID: 0033293462     PISSN: None     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Burr, D. B., Milgrom, C., Fyhrie, D., Forwood, M. R., Nyska, M., Finestone, A., Hoshaw, S., Saiag, E., and Simkin, A., 1996, "In vivo measurement of human tibial strains during vigorous activity," Bone, Vol. 18 pp. 405-410.
2. Cowin, S. C., Weinbaum, S. and Zeng, Y., 1995, "A case for bone canaliculi as the anatomical site of strain generated potentials," J. Biomech, Vol. 28 pp. 1281-1297.
3. Jacobs, C. R., Yellowley, C. E., Davis, B. R., Zhou, Z., Cimbala, J. M. and Donahue, H. J., 1998, "Differential effect of steady versus oscillating flow on bone cells," J. Biomech, Vol. 31 pp. 969-976.
4. Owan, I., Burr, D. B., Turner, C. H., Qiu, J., Tu, Y., Onyia, J. E. and Duncan, R. L., 1997, "Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain," Amer. J. Physiol, Vol. 273 C810-C815.