Transdermal nicotine patches do not cause clinically significant gastroesophageal reflux or esophageal motor disorders

Nicotine and Tobacco Research

Volumn 1, Issue 4, 1999, Pages 371-374

  Wright, Richard A ^a,b   Jane Goldsmith, L ^a,b   Ameen, Vanessa ^a,b   D'Angelo, Annette ^a,b   Kirby, Sherry L ^a,b   Prakash, Sateesh ^a,b  

^a University of Louisville School of Medicine   (United States)

^b McNeil Laboratories Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GANGLION STIMULATING AGENT; NICOTINE;

ADULT; ARTICLE; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DYSPEPSIA; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL MOTILITY; HEARTBURN; HUMAN; INTRADERMAL DRUG ADMINISTRATION; RANDOMIZED CONTROLLED TRIAL; SMOKING CESSATION;

ADMINISTRATION, CUTANEOUS; ADULT; DOUBLE-BLIND METHOD; DYSPEPSIA; GANGLIONIC STIMULANTS; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL MOTILITY; HEARTBURN; HUMANS; NICOTINE; SMOKING CESSATION;

EID: 0033288423     PISSN: 14622203     EISSN: None     Source Type: Journal    
DOI: 10.1080/14622299050011511     Document Type: Article

References (11)

1. Endoh K, Leung FW. 1994. Effects of smoking and nicotine on the gastric mucosa: a review of clinical and experimental evidence. Gastroenterology 107:864-878.
2. Kadakia SC, Kikendall JW, Maydonovitch C, Johnson LF. 1995. Effect of cigarette smoking on gastroesophageal reflux measured by 24-h ambulatory esophageal pH monitoring. American Journal of Gastroenterology 90:1785-1790.
3. Kadakia SC, De La Baume HR, Shaffer RT. 1996. Effects of transdermal nicotine on lower esophageal sphincter and esophageal motility. Digestive Disease Science 41:2130-2134.
4. Kahrilas PJ. 1992. Cigarette smoking and gastroesophageal reflux disease. Digestive Diseases 10:61-71.
5. Kahrilas PJ, Gupta RR. 1989. The effect of cigarette smoking on salivation and esophageal acid clearance. Journal of Laboratory Clinical Medicine 114:431-438.
6. Kahrilas PJ, Gupta RR. 1990. Mechanisms of acid reflux associated with cigarette smoking. Gut 31:4-10.
7. Rahal PS, Wright RA. 1995. Transdermal nicotine and gastroesophageal reflux. American Journal of Gastroenterology 90:919-921.
8. Sandborn WJ, Tremaine WJ, Offord KP, et al. 1997. Transdermal nicotine for mildly to moderately active ulcerative colitis. A randomized, double-blind placebo-controlled trial. Annals of Internal Medicine 126:354-371.
9. Schoeman MN, Tippett MD, Akkermans LM, Dent J, Holloway RH. 1995. Mechanisms of gastroesophageal reflux in ambulant, healthy human subjects. Gastroenterology 108:83-91.
10. Sontag SJ, Schnell TG, Miller TQ, Nemchausky B, Serlovsky R, O'Connell S, et al. 1991. The importance of hiatal hernia in reflux esophagitis compared with lower esophageal sphincter pressure or smoking. Journal of Clinical Gastroenterology 13:628-643.
11. Waring JP, Eastwood TF, Austin JM, Sanowski RA. 1989. The immediate effects of cessation of cigarette smoking on gastroesophageal reflux. American Journal of Gastroenterology 84:1076-1078.