Evidence for a BRACA1 founder mutation in families of west African ancestry [7]

American Journal of Human Genetics

Volumn 65, Issue 2, 1999, Pages 575-578

  Mefford, H C ^a   Baumbach, L ^a   Panguluri, R C K ^a   Whitfield Broome, C ^a   Szabo, C ^a   Smith, S ^a   King, M C ^a   Dunston, G ^a   Stoppa Lyonnet, D ^a   Arena, F ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AFRICA; CONTROLLED STUDY; FEMALE; FOUNDER EFFECT; GENE LOCATION; GENE MUTATION; GENOTYPE; HAPLOTYPE; HUMAN; INHERITANCE; LETTER; MALE; NUCLEOTIDE SEQUENCE; ONCOGENE; PEDIGREE; PRIORITY JOURNAL; AGED; ETHNOLOGY; GENETICS; MIDDLE AGED; MOLECULAR GENETICS; MUTATION; NEGRO; TUMOR SUPPRESSOR GENE;

AFRICA, WESTERN; AFRICAN CONTINENTAL ANCESTRY GROUP; AGED; AGED, 80 AND OVER; FEMALE; FOUNDER EFFECT; GENES, BRCA1; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; PEDIGREE;

EID: 0033237815     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/302511     Document Type: Letter

References (15)

1. SE Antonarakis Recommendations for a nomenclature system for human gene mutations: Nomenclature Working Group Hum Mutat 11 1998 1 3
2. JF Arena S Smith V Vincek L Gayol F Villegas E Perera MC King A BRCA1 founder mutation in African-Americans Am J Hum Genet Suppl 61 1997 A14
3. RB Bar-Sade A Kruglikova B Modan E Gak G Hirsh-Yechezkel L Theodor I Novikov The 185delAG BRCA1 mutation originated before the dispersion of Jews in the diaspora and is not limited to Ashkenazim Hum Mol Genet 7 1998 801 805
4. LS Friedman CI Szabo EA Ostermeyer P Dowd L Butler T Park MK Lee Novel inherited mutations and variable expressivity of BRCA1 alleles, including the founder mutation 185delAG in Ashkenazi Jewish families Am J Hum Genet 57 1995 1284 1297
5. Q Gao S Neuhausen S Cummings M Luce OI Olopade Recurrent germ-line BRCA1 mutations in extended African American families with early-onset breast cancer Am J Hum Genet 60 1997 1233 1236
6. Y Miki J Swensen D Shattuck-Eidens PA Futreal K Harshman S Tavtigian Q Liu A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1 Science 266 1994 66 71
7. SL Neuhausen S Mazoyer L Friedman M Stratton K Offit A Caligo G Tomlinson Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study Am J Hum Genet 58 1996 271 280
8. B Newman H Mu LM Butler RC Millikan PG Moorman M-C King Frequency of breast cancer attributable to BRCA1 in a population-based series of American women JAMA 279 1998 915 921
9. Panguluri RCK, Brody LC, Modali R, Utley K, Adams-Campbell L, Day AA, Whitfield-Broome C, et al. BRCA1 mutations in African Americans. Hum Genet (1999) (in press)
10. DM Parkin SL Whelan J Ferlay L Raymond J Young Cancer incidence in five continents Vol 7 1997 International Association of Cancer Registries Lyon
11. T Peelen M van Vliet A Petrij-Bosch R Mieremet C Szabo AMW van den Ouweland F Hogervorst A high proportion of novel mutations in BRCA1 with strong founder effects among Dutch and Belgian hereditary breast and ovarian cancer families Am J Hum Genet 60 1997 1041 1049
12. A Petrij-Bosch T Peelen M van Vliet R van Eijk R Olmer M Drusdau FBL Hogervorst BRCA1 genomic deletions are major founder mutations in Dutch breast cancer patients Nat Genet 17 1997 341 345
13. J Simard P Tonin F Durocher K Morgan J Rommens S Gingras C Samson Common origins of BRCA1 mutations in Canadian breast and ovarian cancer families Nat Genet 8 1994 392 398
14. TM Smith MK Lee CI Szabo N Jerome M McEuen M Taylor L Hood Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1 Genome Res 6 1996 1029 1049
15. D Stoppa-Lyonnet P Laurent-Puig L Essioux S Pagès G Ithier L Ligot A Fourquet BRCA1 sequence variations in 160 individuals referred to a breast/ovarian family cancer clinic Am J Hum Genet 60 1997 1021 1030