Effects of TGF-β1 on proliferation and IGFBP-3 production in a primary culture of human fetal epiphyseal chondrocytes (HFEC)

Journal of Clinical Endocrinology and Metabolism

Volumn 84, Issue 8, 1999, Pages 2978-2981

  Garcia Ramirez, M ^a   Audi, L ^a   Andaluz, P ^a   Carrascosa, A ^a  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN BINDING PROTEIN 3; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; EPIPHYSEAL CARTILAGE; FETUS; GROWTH INHIBITION; HORMONAL REGULATION; HORMONE RELEASE; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; EPIPHYSIS; FEMALE; METABOLISM; PHYSIOLOGY; PREGNANCY;

CELL DIVISION; CELLS, CULTURED; CHONDROCYTES; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIPHYSES; FEMALE; FETUS; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; PREGNANCY; TRANSFORMING GROWTH FACTOR BETA;

EID: 0033237709     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.84.8.5780     Document Type: Article

References (20)

1. Thyroid hormone effects and identification of specific T3-binding sites in cultured human fetal epiphyseal chondrocytes
2. Chondrocyte differentiation
3. Distinct transforming growth-factor-beta (TGF-β) receptor subsets as determinants of cellular responsiveness to 3 TGF-β isoforms
4. Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur
5. Dihydrocytochalasin B enhances transforming growth factor-β-induced reexpression of the differentiated chondrocyte phenotype without stimulation of collagen synthesis
6. Transforming growth factor-beta and fibroblast growth factor act synergistically to inhibit collagen II synthesis through a mechanism involving regulatory DNA sequences
7. TGF beta 1 prevents hypertophy of epiphyseal chondrocytes: Regulation of gene expression for cartilage matrix proteins and metalloproteases
8. The synergistic effects of vitamin D metabolites and transforming growth factor-β on costochondral chondrocytes are mediated by increases in protein kinase C activity involving two separate pathways
9. The transforming growth factor-β family
10. Transforming growth factor-β-induced cell growth inhibition in human cancer cells is mediated through insulin-like growth factor-binding protein -3 action
11. Insulin-like growth factor (IGF) and IGF-binding proteins: Comparison of human serum and lymph
12. Insulin-like growth factors and their binding proteins: Biological actions
13. Transforming growth factor-β stimulates production of insulin-like growth factor binding protein-3 by human skin fibroblasts
14. Morphologic and metabolic development of human fetal epiphyseal chondrocytes in primary culture
15. Heterogeneity of insulin-like growth factors binding proteins and relationships between structure and affinity. II Forms released by human and rat liver in culture
16. Transforming growth factor-β1 and fibroblast growth factors in rat growth plate
17. Expression and distribution of transforming growth factor-β isoforms and their signaling receptors in growing human bone
18. Regulation of chondrocyte differentiation by transforming growth factors β1, β2, β3, and β5
19. TGF-β-induced G1/M delay in proliferating rabbit articular chondrocytes is associated with an enhancement of replication rate and cAMP decrease: Possible involvement of pertussis toxin-sensitive pathway
20. Expression of a truncated, kinase-defective type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis