Evidence for γδ T cells with a restricted Vδ6 junctional region in the normal mouse central nervous system

Journal of Neuroimmunology

Volumn 100, Issue 1-2, 1999, Pages 260-265

  Szymanska, Bozena ^a   Rajan, Alice J ^b   Gao, Yan Ling ^b   Tronczynska, Ewa ^a   Brosnan, Celia F ^b   Selmaj, Krzysztof ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

T cells; Central nervous system; EAE; Normal mouse; V 6

Indexed keywords

CD8 ANTIGEN; CYTOKINE; FAS ANTIGEN; FAS LIGAND; LYMPHOCYTE ANTIGEN RECEPTOR; T LYMPHOCYTE RECEPTOR; FASL PROTEIN, MOUSE; MEMBRANE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CENTRAL NERVOUS SYSTEM; FEMALE; FLOW CYTOMETRY; IMMUNOREGULATION; IMMUNOSURVEILLANCE; LYMPHOCYTE COUNT; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; T LYMPHOCYTE; ANIMAL; BRAIN; GENETICS; IMMUNOLOGY; LEUKOCYTE; LYMPHOCYTE SUBPOPULATION; METABOLISM; SPINAL CORD; SPLEEN; TISSUE DISTRIBUTION;

ANIMALS; ANTIGENS, CD95; BRAIN; CENTRAL NERVOUS SYSTEM; FAS LIGAND PROTEIN; FEMALE; FLOW CYTOMETRY; LEUKOCYTES; LYMPHOCYTE SUBSETS; MEMBRANE GLYCOPROTEINS; MICE; PHENOTYPE; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPINAL CORD; SPLEEN; T-LYMPHOCYTES; TISSUE DISTRIBUTION;

EID: 0033233286     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(99)00204-0     Document Type: Article

References (32)

1. Allison J.P., Havran W.L. The immunobiology of T cells with invariant γδ antigen receptors. Annu. Rev. Immunol. 9:1991;679-705.
2. Azuara V., Levraud J.P., Lembezat M.P., Pereira P. A novel subset of adult γδ thymocyte that secretes a distinct pattern of cytokines and expresses a very restricted T-cell receptor repertoire. Eur. J. Immunol. 27:1997;544-553.
3. Battistini L., Borsellino G., Sawicki G., Poccia F., Salvetti M., Ristori G., Brosnan C.F. Phenotypic and cytokine analysis of human peripheral blood γδ T cells expressing NK receptors. J. Immunol. 159:1997;3723-3730.
4. Boismenu R., Havran W.L. An innate view of γδ T cells. Curr. Opin. Immunol. 9:1997;57-63.
5. Brosnan C.F., Battistini L., Gao Y.-L., Raine C.S., Aquino D.A. Heat shock proteins and multiple sclerosis: a review. J. Neuropathol. Exp. Neurol. 55:1996;389-402.
6. Cserr H.F., Knopf P.M. Cervical lymphatics, the blood-brain barrier and the immunoreactivity of the brain: a new view. Immunol. Today. 13:1992;507-512.
7. Elliott J.F., Rock E.P., Patten P.A., Davis M.M., Chien Y.H. The adult T-cell receptor δ chain is diverse and distinct from that of fetal thymocytes. Nature. 331:1988;627-631.
8. Ezquerra A., Cron R.Q., McConnell T.J., Valas R.B., Bluestone J.A., Coligan J.E. T-cell receptor δ-gene expression and diversity in mouse spleen. J. Immunol. 145:1990;1311-1317.
9. Fabry Z., Raine C.S., Hart M.N. Nervous tissue as an immune compartment: the dialect of the immune response in the CNS. Immunol. Today. 15:1994;218-224.
10. Haas W., Pereira P., Tonegawa S. Gamma-delta T cells. Annu. Rev. Immunol. 11:1993;637-685.
11. Hahn S., Stadler T., Wernli M., Burgin D., Tschopp J., Nagata S., Erb P. Down-modulation of CD4+ T helper type 2 and type 0 cells by T helper type I cells via Fas/Fas-ligand interaction. Eur. J. Immunol. 25:1995;2679-2685.
12. Happ M.P., Kubo R.T., Palmer E., Born W.K., Brien R.L. Limited receptor repertoire in a mycobacteria-reactive subset of γδ T Lymphocytes. Nature. 342:1989;696-698.
13. Kjeldsen-Kragh J., Quayle A.J., Skalhegg B.S., Sioud M., Forre O. Selective activation of resting human γδ T lymphocytes by interleukin-2. Eur. J. Immunol. 23:1993;2092-2099.
14. LeFrancois L. Intraepithelial lymphocytes of the intestinal mucosa: curiouser and curiouser. Semin. Immunol. 3:1991;99-108.
15. Li H., Lebedeva M.I., Liera A.S., Fields B.A., Brenner M.B., Mariuzza R.A. Structure of the Vδ domain of a human γδ T-cell antigen receptor. Nature. 391:1998;502-506.
16. Medzhitov R., Janeway C.A. Jr. Innate immunity: impact on the adaptive immune response. Curr. Opin. Immunol. 9:1997;4-9.
17. - T-cell receptor γ/δ thymocytes. Eur. J. Immunol. 20:1990;41-45.
18. Nagata S. Fas and Fas ligand: a death factor and its receptor. Adv. Immunol. 57:1994;129-144.
19. O'Brien R.L., Fu Y.-X., Cranfill R., Dallas A., Ellis C., Reardon C., Lang J., Carding S.R., Kubo R., Born W. Heat shock protein Hsp60-reactive γδ T cells: a large, diversified T-lymphocyte subset with highly focused specificity. Proc. Natl. Acad. Sci. U. S. A. 89:1992;4348-4352.
20. Porcelli S.A. The CD1 family: a third lineage of antigen-presenting molecules. Adv. Immunol. 59:1995;1-98.
21. Pryce G., Male D.A., Sarkar C. Control of lymphocyte migration into the brain: selective interactions of lymphocyte populations with brain endothelium. Immunology. 72:1991;393-398.
22. Raulet D.H. The structure, function, and molecular genetics of the γδ T-cell receptor. Annu. Rev. Immunol. 7:1989;175-207.
23. Roark C.E., Vollmer M.K., Cranfill R.L., Carding S.R., Born W.K., O'Brien R.L. TCR junctions reveal differences in heat shock protein-60-reactive cells in liver and spleen. J. Immunol. 150:1993;4867-4875.
24. Schild H., Mavaddat N., Litzenberger C., Bluestone J.A., Matis L., Draper R.K., Chien Y.H. The nature of major histocompatability complex recognition by γδ T cells. Cell. 76:1994;29-37.
25. Sciammas R., Johnson R.M., Sperling A.I., Dick R.F., Spear P.G., Fitch F.W., Bluestone J.A. Unique antigen recognition by a herpes virus-specific TCRγδ cell. J. Immunol. 152:1994;5392-5397.
26. Sciammas R., Kodukula P., Tang Q., Hendricks R.L., Bluestone J.A. T-cell receptor-γδ cells protect mice from Herpes simplex virus type 1-induced lethal encephalitis. J. Exp. Med. 185:1998;1969-1975.
27. Suda T., Okazaki T., Naito Y., Yokota T., Arai N., Ozaki S., Nakao K., Nagata S. Expression of the Fas ligand in cells of T-cell lineage. J. Immunol. 154:1995;3806-3813.
28. Tipold A., Moore P., Jungi T.W., Sager H., Vandevelde M. Lymphocyte subsets and CD45RA positive T-cells in normal canine cerebrospinal fluid. J. Neuroimmunol. 82:1998;90-95.
29. high γδ T cells in lyme arthritis. J. Exp. Med. 184:1996;2109-2117.
30. Wang K., Kuo C.-L., Koop B.F., Hood L. The expression of mouse T-cell receptor TCRDV genes in BALB/c mice. Immunogenetics. 40:1994;271-279.
31. Wen L., Barber D.F., Pao W., Wong F.S., Owen M.J., Hayday A. Primary γδ cell clones can be defined phenotypically and functionally as Th1/Th2 cells and illustrate the association of CD4 with Th2 differentiation. J. Immunol. 160:1998;1965-1974.
32. Williams K.C., Hickey W.F. Traffic of hematogenous cells through the central nervous system. Curr. Top. Microbiol. Immunol. 202:1995;221-245.