Inhibitory effects of cannabinoid receptor ligands on electrically-evoked responses in rat isolated tracheal ring segments

Pharmacological Research

Volumn 40, Issue 5, 1999, Pages 415-421

  Yousif, Mariam H M ^a   Oriowo, Mabayoje A ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Anandamide; CB receptors; SR141716A; WIN 55,212 2

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; ALPHA 2 ADRENERGIC RECEPTOR; ANANDAMIDE; CANNABINOID RECEPTOR; CARBACHOL; LIGAND; PHENTOLAMINE; RECEPTOR SUBTYPE; RIMONABANT;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROSTIMULATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTION; TRACHEA; TRACHEA MUSCLE;

EID: 0033231050     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.1999.0532     Document Type: Article

References (21)

1. Felder CC, Glass M. Cannabinoid receptors and their endogenous agonists. Annu Rev Pharmacol Toxicol 1998; 38: 179-200.
2. Caulfield M, Brown D. Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism. Br J Pharmacol 1992; 106: 231-2.
3. 2+ channels in a neuronal expression system. Mol Pharmacol 1996; 49: 707-14.
4. Pertwee R. The evidence for the existence of cannabinoid receptors. Gen Pharmacol 1993; 24: 811-24.
5. Munro S, Thomas K, Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 1993; 365: 61-5.
6. 2 receptors. Pharmacol Ther 1997; 74: 129-80.
7. Devane WA, Breuer A, Sheskin T, Jarbe T, Eisen M, Mechoulam R. A novel probe for the cannabinoid receptor. J M Chem 1992; 35: 2065-9.
8. Bayewitch M, Avidor-Reiss T, Levy R, Barg J, Mechoulam R, Vogel Z. The peripheral cannabinoid receptor: Adenylate cyclase inhibition and G protein coupling. FEBS Lett 1995; 375: 143-7.
9. Slipetz DM, O'Neil G, Favreau L, Dufresne C, Gallant M, Gareau Y, Guay D, Labelle M, Metters K. Activation of the human peripheral cannabinoid receptor results in inhibition of adenylyl cyclase. Mol Pharmacol 1995; 48: 352-61.
10. Pertwee RG. Griffin G, Lainton JA, Huffman JW. Pharmacological characterization of three novel cannabinoid receptor agonists in the mouse isolated vas deferens. Eur J Pharmacol 1995; 284: 241-7.
11. 1 cannabinoid receptors and possibly also a cannabinoid receptor ligand. Br J Pharmacol 1995; (Proc. Suppl.)116: 46.
12. 1 receptor and endothelium-dependent hyperpolarization in guinea-pig carotid, rat mesenteric and porcine coronary arteries. Br J Pharmacol 1998; 123: 968-74.
13. Plane F, Holland M, Waldron G, Garland C, Boyle J. Evidence that anandamide and EDHF act by different mechanisms in rat isolated mesenteric arteries. Br J Pharmacol 1997; 121: 1509-11.
14. White R, Hiley R. The actions of the cannabinoid receptor antagonist, SR141716A, in the rat isolated mesenteric artery. Br J Pharmacol 1998; 125: 689-96.
15. Pertwee RG, Stevenson LA, Elrick DB, Mechoulam R, Corbett AD. Inhibitory effects of certain enantiomeric cannabinoids in the mouse vas deferens and the myenteric plexus preparation of guinea-pig small intestine. Br J Pharmacol 1992; 105: 980-4.
16. Rinaldi-Carmona M, Barth F, Heaulme M, Shire D, Calandra B, Congy C, Martinez S, Maruani J, Neliat G, Caput D, Ferrara P, Soubrie P, Breliere J, Le Fur G. SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett 1994; 350: 240-4.
17. 1 receptors on peripheral sympathetic nerves. Br J Pharmacol 1996; 118: 2023-8.
18. 2 receptors. Mol Pharmacol 1995; 48: 443-50.
19. 1) cannabinoid receptor antagonist, in rodent brain. Life Sci 1996; 58: 1239-47.
20. 2): identification of cannabinoid receptor subtype selective ligands. J Pharmacol Exp Ther 1996; 278: 989-99.
21. Izzo AA, Mascola N, Borrelli F, Capasso F. Excitatory transmission to the circular muscle of the guinea-pig ileum: Evidence for the involvement of cannabinoid receptors. Br J Pharmacol 1998; 124: 1363-8.