Substrate heterogeneity causes the nonlinear kinetics of insoluble cellulose hydrolysis

Biotechnology and Bioengineering

Volumn 66, Issue 1, 1999, Pages 35-41

  Zhang, Sheng ^a   Wolfgang, David E ^a   Wilson, David B ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

Cellulase; Cellulose hydrolysis; Enzyme inactivation; Nonlinear kinetics; Substrate heterogeneity; Thermomonospora fusca

Indexed keywords

ACTIVATION ENERGY; BIODEGRADATION; CATALYSIS; CATALYST ACTIVITY; ENZYMES; HYDROLYSIS; REACTION KINETICS;

CELLULASE;

CELLULOSE;

CELLULASE; CELLULOSE;

ARTICLE; CHEMICAL REACTION KINETICS; ENZYME INACTIVATION; ENZYME MECHANISM; ENZYME POLYMORPHISM; ENZYME SPECIFICITY; HYDROLYSIS; NONHUMAN; THERMOMONOSPORA;

ACTINOMYCETALES; BACTERIAL PROTEINS; BETA-GLUCOSIDASE; CARBOXYMETHYLCELLULOSE; CELLOBIOSE; CELLULASE; CELLULOSE; CRYSTALLIZATION; HYDROLYSIS; KINETICS; NONLINEAR DYNAMICS; PAPER; SOLUBILITY; SUBSTRATE SPECIFICITY;

EID: 0033230682     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(1999)66:1<35::AID-BIT3>3.0.CO;2-G     Document Type: Article

References (26)

1. Adney WS, Ehrman Cl, Baker JO, Thomas SR, Himmel ME. 1994. Cellulase assays. In: Himmel ME, Baker JO, Overend RP, editors. Enzymatic conversion of biomass for fuels production. Washington, DC: American Chemical Society. p 218-235.
2. Barr BK, Wolfgang DE, Piens K, Claeyssens M, Wilson DB. 1998. Activesite binding of glycosides by Thermomonospora fusca endocellulase E2. Biochemistry. 37:9220-9229.
3. Biely P, Vrsanska M, Claeysens M. 1991. The endo-1,4-β-glucanase I from Trichoderma reesei: Action of β-1,4-oligomers and polymers derived from D-glucose and D-xylose. Eur J Biochem 200:157-163.
4. Bothwell M, Daughhetee S, Chaua G, Wilson DB, Walker L. 1997. Binding capacities for Thermomonospora fusca E3, E4 and E5, the E3 binding domain, and Trichoderma reesei CBHI on Avicel and bacterial microcrystalline cellulose. Bioresource Technol 60:169-178.
5. Breuil C, Chan M, Gilbert M, Saddler JN. 1991. Influence of β-glucosidase on the filter paper activity and hydrolysis of lignocellulosic substrates. Bioresource Technol 39:139-142.
6. Calza RE, Irwin DC, Wilson DB. 1985. Purification and characterization of two β-1,4-endoglucanases from Thermomonospora fusca. Biochemistry 24:7797-7804.
7. Coughlan M. 1990. In: Fogarty WM, Kelley CT, editors. Microbial Enzymes and Biotechnology. London: Elsevier Applied Science. p 1-36.
8. Desai SC, Converse AO. 1997. Substrate reactivity as a function of the extent of reaction in the enzymatic hydrolysis of cellulose. Biotechnol Bioeng 56:650-655.
9. Irwin D, Walker L, Spezio M, Wilson D. 1993. Activity studies of eight purified cellulases: specificity, synergism, and binding domain effects. Biotechnol Bioeng 42:1002-1013.
10. Miller GL, Blum R, Glennin WE, Benton AL. 1960. Measurement of carboxymethyl cellulase activity. Anal Biochem 21:127-132.
11. Nidetzky B, Steiner W. 1993. A new approach for modeling cellulase-cellulose adsorption and the kinetics of hydrolysis of cellulose. Biotechnol Bioeng 42:469-479.
12. Nidetzky B, Steiner W, Claeyssens M. 1995. Synergistic interaction of cellulases from Trichoderma reesei during cellulose degradation. In: Saddler JN, MHP, editor. Enzymatic degradation of insoluble carbohydrate. Washington DC: American Chemical Society. p 90-112.
13. Nidetzky B, Steiner W, Hayn M, Claeyssens, M. 1994. Cellulose hydrolysis by the cellulases from Trichoderma reesei: A new model for synergistic interaction. Biochem J 298:705-710.
14. Sattler W, Esterbauer H, Glatter O, Steiner W. 1989. The effect of enzyme concentration on the rate of the hydrolysis of cellulose. Biotechnol Bioeng 33:1221-1234.
15. Schou C, Rasmussen G, Katoft MB, Henrissat B, Schulein M. 1993. Stereochemistry, specificity and kinetics of the hydrolysis of reduced cellodextrins by nine cellulases. Eur J Biochem FEBS 217:947-953.
16. Segel IH. 1975. Biochemical calculations. New York: John Wiley & Sons.
17. Spezio M, Wilson DB, Karplus PA. 1993. Crystal structure of the catalytic domain of a thermophilic endocellulase. Biochemistry 32:9906-9916.
18. Teeri T. 1997. Crystalline cellulose degradation: New insight into the function of cellobiohydrolases. Trends Biotechnol 15:160-167.
19. Walker LP, Belair CD, Wilson DB, Irwin DC. 1993. Engineering cellulase mixtures by varying the mole fraction of Thermomonospora fusca E5 and E3, Trichoderma reesei CBHI, and Caldocellulosiruptor saccharotyticum β-glucosidase. Biotechnol Bioeng 42:1019-1028.
20. Warren RAJ. 1996. Microbial hydrolysis of polysaccharides. Annu Rev Microbiol 50:183-212.
21. Wilson DB. 1988. Cellulases of Thermomonospora fusca. Methods Enzymol 160:314-323.
22. Wilson DB, Irwin D. Genetics and properties of cellulases. In: Tsao GT, Scheper Z, editors. Recent progress in bioconversion of lignocellulosics. Berlin: Springer-Verlag. In press.
23. Wolfgang DE. 1998. Mechanistic studies of active site mutants of Thermomonospora fusca endocellulase E2. PhD thesis, Cornell University, Ithaca, NY.
24. Woodward J. 1991. Synergism in cellulase systems. Bioresource Technol 36:67-75.
25. Wyman DKB, RL, Hinman ND, Stevens DJ. 1993. Ethanol and methanol from cellulosic biomass. In: Johannson TE, Kelly H, Reddy AKN, Williams RA, editors. Renewable energy: Sources for fuels and electricity. Washington, DC: Island Press. p 865-923.
26. Zhang S, Wilson DB. 1997. Surface residue mutations which change the substrate specificity of Thermomonospora fusca endoglucanase E2. J Biotechnol 57: 101-113.