Secretion-dependent proteolysis of heterologous protein by recombinant Escherichia coli is connected to an increased activity of the energy- generating dissimilatory pathway

Biotechnology and Bioengineering

Volumn 66, Issue 1, 1999, Pages 61-67

  Schmidt, Michael ^a,d   Viaplana, Elisenda ^b,c   Hoffmann, Frank ^a   Marten, Sabine ^a   Villaverde, Antonio ^b   Rinas, Ursula ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c Fort Dodge Veterinaria   (Spain)

^d Chr Hansen Nienburg GmbH   (Germany)

Author keywords

Carbon metabolism; Proteolytic degradation; Recombinant protein; Stress response

Indexed keywords

BIODEGRADATION; BIOMASS; BIOSYNTHESIS; CARBON; CELL CULTURE; ESCHERICHIA COLI; METABOLISM;

PROTEOLYTIC DEGRADATION;

PROTEINS;

BACTERIAL PROTEIN;

ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; ESCHERICHIA COLI; NONHUMAN; PROTEIN DEGRADATION; PROTEIN STABILITY; STRESS;

ADENOSINE TRIPHOSPHATE; ATP-DEPENDENT PROTEASES; BACTERIAL PROTEINS; BIOREACTORS; CARBON; CELL DIVISION; ENERGY METABOLISM; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE DELETION; HEAT-SHOCK PROTEINS; INCLUSION BODIES; PROTEASE LA; RECOMBINANT FUSION PROTEINS; SERINE ENDOPEPTIDASES; VIRAL STRUCTURAL PROTEINS;

EID: 0033230145     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(1999)66:1<61::AID-BIT6>3.0.CO;2-G     Document Type: Article

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