2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) blocks ovulation by a direct action on the ovary without alteration of ovarian steroidogenesis: Lack of a direct effect on ovarian granulosa and thecal-interstitial cell steroidogenesis in vitro

Reproductive Toxicology

Volumn 13, Issue 6, 1999, Pages 521-530

  Son, Deok Soo ^a   Ushinohama, Kanji ^a   Gao, Xin ^b   Taylor, Christopher C ^a   Roby, Katherine F ^a,b   Rozman, Karl K ^b,c   Terranova, Paul F ^a  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

AhR; CYP1A1; Granulosa cell; Immature hypophysectomized rat; Ovulation; Steroidogenesis; TCDD; Thecal interstitial cell

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ANDROSTENEDIONE; AROMATIC HYDROCARBON RECEPTOR; ESTRADIOL; PROGESTERONE; STEROID;

ANDROSTENEDIONE BLOOD LEVEL; ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; ESTRADIOL BLOOD LEVEL; FEMALE; GENE EXPRESSION REGULATION; GENETICS; GRANULOSA CELL; HORMONAL REGULATION; HUMAN; METABOLISM; NONHUMAN; OVARY; OVARY CELL; OVARY FUNCTION; OVULATION; OVULATION INHIBITION; PHYSIOLOGY; POLLUTANT; PROGESTERONE BLOOD LEVEL; RAT; RAT STRAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEROIDOGENESIS; THECA CELL;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FEMALE; GENE EXPRESSION REGULATION; GRANULOSA CELLS; HUMANS; OVARY; OVULATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ARYL HYDROCARBON; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEROIDS; TETRACHLORODIBENZODIOXIN; THECA CELLS;

ANIMALIA; EQUIDAE;

EID: 0033226697     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(99)00048-9     Document Type: Article

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