2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) increases release of luteinizing hormone and follicle-stimulating hormone from the pituitary of immature female rats in vivo and in vitro

Toxicology and Applied Pharmacology

Volumn 142, Issue 2, 1997, Pages 264-269

  Li, Xuelin ^a   Johnson, Donald C ^b   Rozman, Karl K ^a,c  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CALCIUM; FOLLITROPIN; GONADORELIN; GONADORELIN ANTAGONIST; LUTEINIZING HORMONE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; FEMALE; HORMONAL REGULATION; HORMONE RECEPTOR INTERACTION; LUTEINIZING HORMONE RELEASE; NEWBORN; NONHUMAN; PATHOPHYSIOLOGY; RADIOIMMUNOASSAY; RAT; RECEPTOR UPREGULATION;

ANIMALIA; ZEA MAYS;

EID: 0031062305     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1996.8044     Document Type: Article

References (26)

1. Brann, D. W., and Mahesh, V. B. (1991). Role of corticosteroids in female reproduction. FASEB J. 5(12), 2691-2698.
2. DeVito, M. J., Thomas, T., Martin, E., Umbreit, T. H., and Gallo, M. A. (1992). Antiestrogenic action of 2,3,7,8-tetrachlorodibenzo-p-dioxin: Tissue specific regulation of estrogen receptor in CD-1 mice. Toxicol. Appl. Pharmacol. 113, 284-292.
3. Harris, M., Piskorska-Pliszczynska, J., Zacharewski, T., Romkes, M., and Safe, S. (1989). Structure-dependent induction of aryl hydrocarbon hydroxylase in human breast cancer cell lines and characterization of the Ah receptor. Cancer Res. 49(16), 4531-4535.
4. Humphries, J., Wan, Y. P., Folkers, K., and Bowers, C. Y. (1978). Inhibitory analogues of the luteinizing hormone-releasing hormone having D-aromatic residues in positions 2 and 6 and variation in position 3. J. Med. Chem. 21(1), 120-123.
5. Kello, D., and Yrjanheikki, E. (1992). Assessment of health hazards associated with exposure to dioxins. Chemosphere 25, 1067-1070.
6. Kenaga, E. E., and Norris, L. A. (1983). Environmental toxicity of TCDD. Environ. Sci. Res. 26, 277-299.
7. 2+-homeostasis in rat cerebellar granule cells. Toxicol. Appl. Pharmacol. 123, 97-106.
8. Kodavanti, P. R. S., Shafer, T. J., Ward, T. R., Mundy, W. R., Freudenrich, T., Harry, G. J., and Tilson, H. A. (1994). Differential effects of polychlorinated biphenyl congeners on phosphoinositide hydrolysis and protein kinase C translocation in rat cerebellar granule cell. Brain Res. 662, 75-82.
9. Li, X., Weber, L. W. D., and Rozman, K. K. (1995a). Toxicokinetics of TCDD in female Sprague-Dawley rats including placental and lactational transfer to fetuses and neonates. Fundam. Appl. Toxicol. 27(1), 70-76.
10. Li, X., Johnson, D. C., and Rozman, K. K. (1995b). Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on cyclicity and ovulation in female Sprague-Dawley rats. Toxicol. Lett. 78(3), 219-222.
11. Li, X., Johnson, D. C., and Rozman, K. K. (1995c). Reproductive effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in female rats: Ovulation, hormonal regulation and possible mechanism. Toxicol. Appl. Pharmacol. 133(2), 321-327.
12. McConnell, E. E. (1980). Acute and chronic toxicity, carcinogenesis, reproduction, teratogenesis and mutagenesis in animals. In Halogenated Biphenyls, Terphenyls, Napthalenes, Dibenzodioxins and Related Products (R. D. Kimbrough, Ed.), p. 109. Elsevier, Amsterdam.
13. McKelvy, J. F., Le Blanc, P., Loudes, C., Perrie, S., Grimm-Jorgensen, Y., and Kordon, C. (1976). The use of bacitracin as an inhibitor of the degradation of thyrotropin-releasing factor and luteinizing hormone-releasing factor. Biochem. Biophys. Res. Commun. 73, 507-512.
14. Nishizuka, Y. (1986). Studies and perspective of protein kinase C. Science 233, 305.
15. Nishizuka, Y. (1988). The molecular hetrogencity of protein kinase C and its implication for cellular regulation. Nature 334, 661-665.
16. Paker, P., Coussens, L., Totty, N., Rhee, L., Young, S., Chen, E., Stabel, S., Waterfield, M. D., and Ullrich, A. (1986). The complete primary structure of protein kinase C-the major phorbor ester receptor. Science 233, 853.
17. Peterson, R. E., Theobald, H. M., and Kimmel, G. L. (1993). Developmental and reproductive toxicity of dioxins and related compounds: Cross-species comparisons. Crit. Rev. Toxicol. 23(3), 283-335.
18. Powers, C. A., and Johnson, D. C. (1981). Peptidase regulation of gonadotropin-releasing hormone levels during in vitro incubations of the rat hypothalamus. J. Neurochem. 36, 670-676.
19. Powers, C. A., and Johnson, D. C. (1984). Correlation of LH, FSH and GnRH release during various brain-pituitary coincubations. Horm. Res. 19(2), 117-126.
20. Ruangwises, S., Bestervelt, L. L., Piper, D. W., Nolan, C. J., and Piper, W. N. (1991). Human chorionic gonadotropin treatment prevents depressed 17 alpha-hydroxylase/C17-20 lyase activities and serum testosterone concentrations in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats. Biol. Reprod. 45(1), 143-150.
21. Safe, S., Astroff, B., Harris, M., Zacharewaki, T., Dickerson, R., Romkes, M., and Biegel, L. (1991). 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds as antiestrogens: Characterization and mechanism of action. Pharmacol. Toxicol. 69, 400-409.
22. Shiverick, K. T., and Muther, T. F. (1983). 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) effects on hepatic microsomal steroid metabolism and serum estradiol of pregnant rats. Biochem. Pharmacol. 32(6), 991-995.
23. Suter, D. E., and Schwartz, N. B. (1985). Effects of glucocorticoids on responsiveness of luteinizing hormone and follicle-stimulating hormone to gonadotropin-releasing hormone by male rat pituitary cells in vitro. Endocrinology 117(3), 855-859.
24. Thomson, F. J., Hohnson, M. S., Mitchell, R., Wolbers, W. B., Ison, A. J., and MacEwan, D. J. (1993). The differential effects of protein kinase C activators and inhibitors on rat anterior pituitary hormone release. Mol. Cell. Endocrinol. 94, 223-234.
25. Puga, A., Nebert, D. W., and Carrier, F. (1992). Dioxin induces expression of c-fos and c-jun proto-oncogenes and a large increase in transcription factor AP-1. DNA Cell Biol. 11, 269-281.
26. Yrjanheikki, E. J. (1989). Levels of PCBs, PCDDs, and PCDFs in breast milk. WHO Environ. Health 34, 92.