Vortex Shedding in Steady Flow Through a Model of an Arterial Stenosis and Its Relevance to Mural Platelet Deposition

Annals of Biomedical Engineering

Volumn 27, Issue 6, 1999, Pages 763-773

  Bluestein, Danny ^a   Gutierrez, Carlos ^b   Londono, Mateo ^b   Schoephoerster, Richard T ^b  

^a STONY BROOK UNIVERSITY   (United States)

^b The Department of Electrical and Computer Engineering   (United States)

Author keywords

Blood flow; Cardiovascular pathologies; CFD; DPIV; Platelet activation and aggregation

Indexed keywords

ANIMAL; ARTICLE; BIOLOGICAL MODEL; BLOOD; BLOOD RHEOLOGY; DOG; HEART DISEASE; LASER DOPPLER FLOWMETRY; MATHEMATICAL COMPUTING; PATHOPHYSIOLOGY; PERIPHERAL OCCLUSIVE ARTERY DISEASE; REPRODUCIBILITY; THERMODYNAMICS; THROMBOCYTE ADHESIVENESS; THROMBOSIS; VIDEORECORDING;

ANIMALS; ARTERIAL OCCLUSIVE DISEASES; CONVECTION; DOGS; HEART DISEASES; HEMORHEOLOGY; LASER-DOPPLER FLOWMETRY; MODELS, CARDIOVASCULAR; NUMERICAL ANALYSIS, COMPUTER-ASSISTED; PLATELET ADHESIVENESS; REPRODUCIBILITY OF RESULTS; THROMBOSIS; VIDEOTAPE RECORDING;

EID: 0033220117     PISSN: 00906964     EISSN: None     Source Type: Journal    
DOI: 10.1114/1.230     Document Type: Article

References (30)

1. Addonizio, V. P., and Z. H. Edmunds. Thromboembolic complications of prosthetic valves. Cardiovasc. Clinics. 3:431-435, 1985.
2. Ahmed, S. A. and D. P. Giddens. Velocity measurements in steady flow through axisymmetric stenoses at moderate Reynolds numbers. J. Biomech. 16:505-516, 1983.
3. Bluestein, D., L. Niu, R. T. Schoephoerster, and M. K. Dewanjee. Fluid mechanics of arterial stenosis: Relationship to the development of mural thrombus. Ann. Biomed. Eng. 25:344-356, 1997.
4. Chandran, K. B. Heart valve prostheses: In vitro flow dynamics, in Encyclopedia for Medical Instrumentation, edited by J. G. Webster. New York: Wiley, 1988, Vol. 3, pp. 1475-1483.
5. Dewanjee, M. K., S. A. Rao, and P. Didisheim. Indium-111 tropolone, a new platelet label: Preparation and evaluation of labeling parameters. J. Nucl. Med. 22:981-987, 1981.
6. Dewanjee, M. K. In-111 platelets in bypass grafts: Experimental and clinical applications, in Radiolabeled Cellular Elements of Blood, edited by M. L. Thakur, M. Hardeman, and M. D. Ezekowitz. New York: Plenum, 1985, pp. 229-263.
7. Dintenfass, L. Rheological approach to thrombosis and atherosclerosis. Angiology 15:333-343, 1964.
8. Fearn, R. M., T. Mullin, and K. A. Cliffe. Nonlinear flow phenomena in a symmetric sudden expansion. J. Fluid Mech. 211:595-608, 1990.
9. Gosman, A. D., and L. Ioannides. Aspects of computer simulation of liquid-fueled cumbustors, AIAA 19th Aerospace Science Meeting, Paper no. 81-0323, 1981.
10. Gross, J. M., C. D. Shermer, and N. H. C. Hwang. Vortex shedding in bileaflet heart valve prostheses. Trans. Am. Soc. Artif. Intern. Organs 34:845-850, 1988.
11. Guyton, A. C. Textbook of Medical Physiology, eighth ed. Philadelphia: Saunders, 1991, pp. 390-399.
12. Hussain, A. K. M. F. Mechanics of pulsatile flows of relevance to the cardiovascular system. In Cardiovascular Flow Dynamics and Measurements, edited by N. H. C. Hwang and N. A. Norman: University Park Press, 1975, Chap. 15, pp. 541-633.
13. A. K. M. F. Hussain. Coherent structures and turbulence. J. Fluid Mech. 173:303-356, 1986.
14. Merrill, E. W., E. R. Gilliland, G. R. Cokelet, H. Shin, A. Britten, and R. E. Wells. Rheology of human blood, near and at zero flow. Biophys. J. 3:199-213, 1963.
15. Muneretto, C., E. Solis, A. Pavie, P. Leger, I. Gandjbakhch, J. Szefner, V. Bors, C. Piazza, A. Cabrol, and C. Cabrol. Total artificial heart: Survival and complications, Ann. Thorac. Surg. 47:151-157, 1989.
16. Ojha, M. Flow separation and the transition to unsteadiness, Advances in Bioengineering, New York: ASME, 1995, Vol. 29, pp. 347-348.
17. Ojha, M., R. S. C. Cobbold, K. W. Johnston, and R. L. Hummel. Pulsatile flow through constricted tubes: an experimental investigation using photochromic tracer methods. J. Fluid Mech. 203:173-197, 1989.
18. Pauley, L. L., P. Moin, and W. C. Reynolds. The structure of two-dimensional separation. J. Fluid Mech. 220:397-411, 1990.
19. Saad, Y. and M. H. Schultz. GMRES: a generalized minimal residuals algorithm for solving nonsymmetric linear systems. Math. Comput. 44:417-424, 1983.
20. Schoephoerster, R. T., F. Oynes, G. Nunez, M. Kapadvanjwala, and M. K. Dewanjee. Effects of local geometry and fluid dynamics on regional platelet deposition on artificial surfaces. Arterioscler. Thromb. 13:1806-1813, 1993.
21. Stein, P. D. and H. N. Sabbah. Measured turbulence and its effect on thrombus formation. Circ. Res. 35:608-614, 1974.
22. Thornburg, H. J., U. Ghia, G. A. Osswald, and K. N. Ghia. Efficient computation of vortical flow using flow-adaptive time-dependent grids. Fluid Dyn. Res. 10:371-397, 1992.
23. White, F. M. Fluid Mechanics. New York: McGraw-Hill, 1979, pp. 278-279.
24. Wilcox, D. C. Turbulence Modeling for CFD. La Canada, California: DWC Industries, 1993.
25. Wilcox, D. C.. Simulation of transition with a two-equation turbulence model. AIAA J. 32:247-255, 1994.
26. Willert, C. E. and M. Gharib. Digital particle image velocimetry. Exp. Fluids 10:181-193, 1991.
27. Wurzinger, L. J. and H. Schmid-Schoenbein. The role of fluid dynamics in triggering and amplifying hemostatic reactions in thrombogenesis. Blood flow in large arteries: Application to Atherogenesis and Clinical Medicine. Monogr. Atheroscler. Liepsch (ed): Basel, Karger, 1990. Vol. 15, pp. 215-226.
28. Yellin, E. L.. Laminar-turbulent transition process in pulsatile flow. Circ. Res. 19:791-804, 1966.
29. Yoganathan, A. P., N. H. Corcoran, E. C. Harrison, and J. R. Carl. The Bjork-Shiley aortic prosthesis: Flow characteristics, thrombus formation and tissue overgrowth. Circulation 53:70-75, 1978.
30. Young, D. F.. Fluid mechanics of arterial stenosis. J. Biomech. Eng. 101:157-175, 1979.