Fluid mechanics of arterial stenosis: Relationship to the development of mural thrombus

Annals of Biomedical Engineering

Volumn 25, Issue 2, 1997, Pages 344-356

  Bluestein, Danny ^a,c   Niu, Lijun ^a   Schoephoerster, Richard T ^a   Dewanjee, Mrinal K ^b,d  

^a The Department of Electrical and Computer Engineering   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c STONY BROOK UNIVERSITY   (United States)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Arterial stenosis; Fluid mechanics; Mural thrombus; Platelet deposition

Indexed keywords

BLOOD VESSELS; CELLS; JETS; LAMINAR FLOW; REYNOLDS NUMBER; SHEAR STRESS; STRESS CONCENTRATION; TURBULENT FLOW; VELOCITY MEASUREMENT;

ARTERIAL STENOSIS; DIGITAL PARTICLE IMAGE VELOCIMETRY; MURAL THROMBUS; PLATELETS;

HEMODYNAMICS;

ARTERY OCCLUSION; ARTICLE; BLOOD FLOW; DYNAMICS; MECHANICS; SHEAR RATE; THROMBOCYTE ACTIVATION; THROMBOGENESIS;

ALGORITHMS; BIOMECHANICS; CORONARY DISEASE; HEMORHEOLOGY; MODELS, CARDIOVASCULAR; NUMERICAL ANALYSIS, COMPUTER-ASSISTED; PLATELET ACTIVATION; THROMBOSIS;

EID: 0031105449     PISSN: 00906964     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02648048     Document Type: Article

References (26)

1. Aarts, P. A., M. M. van Den, S. A. T. Broek, G. W. Prins, D. C, Kuiken, J. J. Sixma, and R. M. Heethaar. Blood platelets are concentrated near the wall and red blood cells, in the center in flowing blood. Arteriosclerosis 8:819-824, 1988.
2. Badimon, L., and J. J. Badimon. Mechanisms of arterial thrombosis in nonparallel streamlines: platelet thrombi grow on the apex of stenotic severely injured vessel wall. J. Clin. Invest. 84:1134-1144, 1989.
3. Basmadjian, D. The effect of flow and mass transport in thrombogenesis. Ann. Biomed. Eng. 18:685-709, 1990.
4. Christenson, J. T., J. Mergerman, K. C. Hanel, G. J. L'Italien, H. W. Strauss, and W. M. Abbott. The effect of blood flow rates on platelet deposition in PTFE arterial bypass grafts. Trans. ASAIO J. 27:188-191, 1981.
5. Colantuoni, G., J. D. Hellums, J. L. Moake, and C. P. Alfrey, Jr. Response of human platelets to shear stress at short exposure times. Trans. Am. Soc. Artif. Organs 23:626-630, 1977.
6. Deshpande, M. D., and D. P. Giddens. Computation of turbulent flow through constrictions. Eng. Mech. 109: 466-471, 1983.
7. Dewanjee, M. K., M. Kapadvanjwala, W.-W. Mao, W. Jy. Y. Ahn, K. Ruzius, A. K. Ghafouripour, A. N. Serafini, and G. N. Sfakianakis. A higher blood flow window of reduced thrombogenicity and acceptable fragmentation in a hollow fiber hemodialyzer. ASAIO J. 39: M363-M367, 1993.
8. Eckstein, E. C., and F. Belgacem. Model of platelet transport in flowing blood with drift and diffusion terms. Biophys. J. 60:53-69, 1991.
9. Eldrup-Jorgensen, J., W. C. Mckey, and R. J. Connoly. Evaluation of arterial prosthesis in a baboon ex vivo shunt: the effect of graft material and flow on platelet deposition. Am. J. Surg. 150:185-190, 1985.
10. Folie, B. J., and L. V. Mclntire. Mathematical analysis of mural thrombogenesis: concentration profiles of platelet-activating agents and effects of viscous shear flow. Biophys. J. 56:1121-1141, 1989.
11. Hellums, J. D. Biorheology in thrombosis research. Ann. Biomed. Eng. 22:445-455, 1994.
12. Hellums, J. D., D. M. Peterson, N. A. Stathopoulos, J. L. Moake, and T. D. Giorgio. Studies on the mechanisms of shear-induced platelet activation. In: Cerebral ischemia and hemorheology, edited by A. Hartman and W. Kuschinsky. New York: Springer-Verlag, 1987. pp. 80-89.
13. Karino, T., and H. L. Goldsmith. Aggregation of human platelets in an annular vortex distal to a tubular expansion. Microvasc. Res. 17:217-237, 1979
14. Karino, T., and H. L. Goldsmith. Adhesion of human platelets to collagen on the walls distal to a tubular expansion. Microvasc. Res. 17:238-262, 1979.
15. Karino, T., H. L. Goldsmith, M. Motomiya, S. Mabuchi, and Y. Sohara. Flow patterns in vessels of simple and complex geometries. In: Blood in contact with natural and artificial surfaces, edited by E. F. Leonard, V. T. Turitto, and L. Vroman. New York: New York Academy of Sciences, 1987, pp. 422-441.
16. Lassila R., J. J. Badimon, S. Vallabhajosula, and L. Badimon. Dynamic monitoring of platelet deposition on severely damaged vessel wall in flowing blood. Arteriosclerosis 10:306-315, 1990.
17. Lelah, M. D., L. K. Lamprecht, and S. L. Cooper. A canine ex vivo series shunt for evaluating thrombus deposition on polymer surfaces. J. Biomed. Mater. Res. 18:475-496, 1984.
18. Purvis, N. B., and T. D. Giorgio. The effects of elongational stress exposure on the activation and aggregation of blood platelets. Biorheology 28:355-367, 1991.
19. Ramstack, J. M., L. Zuckerman, and L. F. Mockros. Shear induced activation of platelets. J. Biomech. 12: 113-125, 1979.
20. Schoephoerster, R. T., F. Oynes, H. Nunez, M. Kapadvanjwala, and M. K. Dewanjee. Effects of local geometry and fluid dynamics on regional platelet deposition on artificial surfaces. Atheroscler. Thromb. 12:1806-1813, 1993.
21. Stein, P. D., and H. N. Sabbah. Measured turbulence and its effect on thrombus formation. Circ. Res. 35:608-614, 1974.
22. Sutera, S. P., M. D. Nowak, J. H. Joist, D. J. Zeffren, and J. E. Bauman. A programmable, computer-controlled, cone-plate viscometer for the application of pulsatile shear stress to platelet suspensions. Biorheology 25:449-459, 1988.
23. Tangelder, G. J., D. W. Slaaf, H. C. Teirlink, R. Alewijnse, and R. S. Reneman. Localization within a thin optical section of fluorescent blood platelets flowing in a microvessel. Microvasc. Res. 23:214-230, 1982.
24. Wurzinger, L. J., P. Blasberg, and H. Schmid-Schönbein. Towards a concept of thrombosis in accelerated flow: rheology, fluid dynamics, and biochemistry. Biorheology 22:437-449, 1985.
25. Young, D. F. Fluid mechanics of arterial stenosis. J. Biomech. Eng. 101:157-175, 1979.
26. Young, D. F., and F. Y. Tsai, Flow characteristics in models of arterial stenosis. I. Steady flow. J. Biomech. 76:395-410, 1973.