Mono-allelic Ly49 NK cell receptor expression

Seminars in Immunology

Volumn 11, Issue 5, 1999, Pages 349-355

  Held, Werner ^a   Kunz, Béatrice ^b   Ioannidis, Vasilios ^b   Lowin Kropf, Bente ^b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b NONE

Author keywords

Allele; Ly49; MHC class I; NH cell; Stochastic

Indexed keywords

GROWTH FACTOR; LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR;

ALLELE; AUTOSOME; GENE CONTROL; GENETIC VARIABILITY; HUMAN; IMMUNOGENETICS; NATURAL KILLER CELL; NONHUMAN; OLFACTORY RECEPTOR; RECEPTOR GENE; REVIEW; X CHROMOSOME LINKAGE;

EID: 0033215260     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1006/smim.1999.0191     Document Type: Article

References (33)

1. Zhang B., Yamamura T., Kondo T., Fujiwara M., Tabira T. Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells. J Exp Med. 186:1997;1677-1687.
2. Ljunggren H.G., Karre K. In search of the `missing self': MHC molecules and NK cell recognition. Immunol Today. 11:1990;237-244.
3. Ohlen C., Kling G., Höglund P., Hansson M., Scangos G., Bieberich C., Jay G., Karre K. Prevention of allogenic bone marrow graft rejection by H-2 transgene in donor mice. Science. 246:1989;666-668.
4. Vaage J.T., Naper C., Lovik G., Lambracht D., Rehm A., Hedrich H.J., Wonigeit K., Rolstad B. Control of rat natural killer cell-mediated allorecognition by a major histocompatibility complex region encoding nonclassical class I antigens. J Exp Med. 180:1994;641-651.
5. Moretta A., Sivori S., Vitale M., Pende D., Morelli L., Augugliaro R., Bottino C., Moretta L. Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells. J Exp Med. 182:1995;875-884.
6. Lanier L.L., Corliss B., Phillips J.H. Arousal and inhibition of human NK cells. Immunol Rev. 155:1997;145-154.
7. Karlhofer F.M., Ribaudo R.K., Yokoyama W.M. MHC class I alloantigen specificity of Ly-49+IL-2 activated natural killer cells. Nature. 358:1992;66-70.
8. McQueen K.L., Freeman J.D., Takei F., Mager D.L. Localization of five new Ly49 genes, including three closely related to Ly49c. Immunogenetics. 48:1998;174-183.
9. Smith H.R.C., Karlhofer F.M., Yokoyama W.M. Ly-49 multigene family expressed by IL-2-activated NK cells. J Immunol. 153:1994;1068-1079.
10. Wong S., Freeman J.D., Kelleher C., Mager D., Takei F. Ly-49 multigene family. New members of a superfamily of type II membrane proteins with lectin-like domains. J Immunol. 147:1991;1417-1423.
11. Brown M.G., Fulmek S., Matsumoto K., Cho R., Lyons P.A., Levy E.R., Scalzo A.A., Yokoyama W.M. A 2-Mb YAC contig and physical map of the natural killer gene complex on mouse chromomsome 6. Genomics. 42:1997;16-25.
12. Brown M.G., Scalzo A.A., Matsumoto K., Yokoyama W.M. The natural killer gene complex: a genetic basis for understanding natural killer cell function and innate immunity. Immunol Rev. 155:1997;53-66.
13. Colonna M., Samaridis J. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. Science. 268:1995;405-408.
14. Correa I., Raulet D.H. Binding of diverse peptides to MHC class I molecules inhibits target cell lysis by activated natural killer cells. Immunity. 2:1995;61-71.
15. Malnati M.S., Peruzzi M., Parker K.C., Biddison W.E., Ciccone E., Moretta A., Long E.O. Peptide specificity in the recognition of MHC class I by natural killer cell clones. Science. 267:1995;1016-1018.
16. Raulet D.H., Held W., Correa I., Dorfman J., Wu M-F, Corral L. Specificity, tolerance and developmental regulation of natural killer cells defined by expression of class I specific Ly49 receptors. Immunol Rev. 155:1997;41-52.
17. Burshtyn D., Scharenberg A., Wagtmann N., Rajagopalan S., Peruzzi M., Kinet J-P, Long E.O. Recruitment of tyrosine phosphatase HCP by the NK cell inhibitory receptor. Immunity. 4:1996;77-85.
18. Nakamura M.C., Niemi E.C., Fisher M.J., Shultz L.D., Seaman W.E., Ryan J.C. Mouse Ly-49A interrupts early signaling events in NK cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase. J Exp Med. 147:1997;3244-3250.
19. Lanier L.L., Corliss B.C., Wu J., Leong C., Phillips J. Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells. Nature. 391:1998;703-707.
20. Nakamura M.C., Linnemeyer P.A., Niemi E.C., Mason L.H., Ortaldo J.R., Ryan J.C., Seaman W.E. Mouse Ly49D recognizes H-2Dd and activates natural killer cell cytotoxicity. J Exp Med. 189:1999;493-500.
21. Held W., Dorfman J.R., Wu M-F, Raulet D.H. Major histocompatibility complex class I dependent skewing of the natural killer cell Ly49 receptor repertoire. Eur J Immunol. 26:1996;2286-2292.
22. Valiante N.M., Uhrberg M., Shilling H.G., Lienert-Weidenbach K., Arnett K.L., D'Andrea A., Phillips J.H., Lanier L.L., Parham P. Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity. 7:1998;739-751.
23. Johansson M.H., Bieberich C., Jay G., Kärre K., Höglund P. Natural killer cell tolerance in mice with mosaic expression of major histocompatibility complex class I molecules. J Exp Med. 186:1997;353-364.
24. Williams N.S., Klem J., Puzanov I.J., Sivakumar P.V., Schatzle J.D., Bennett M., Kumar V. Natural killer cell differentiation: insights from knockout and transgenic mouse models and in vitro systems. Immunol Rev. 165:1998;47-61.
25. Ogasawara K., Hida S., Azimi N., Tagaya Y., Sato T., Yokochi-Fukuda T., Waldmann T.A., Taniguchi T., Taki S. Requirement for IRF-1 in the microenvironment supporting development of natural killer cells. Nature. 391:1998;700-703.
26. Williams N.S., Moore T.A., Schatzle J.D., Puzanov I.J., Sivakumar P.A., Zlotnik A., Bennett M., Kumar V. Generation of lytic natural killer 1.1+, Ly49-cells from mutlipotent murine bone marrow progenitors in a stroma-free culture: definition of cytokine requirements and developmental intermediates. J Exp Med. 186:1997;1609-1614.
27. Toomey J.A., Shrestha S., de la Rue SA, Gayes F., Robinson J.H., Chrzanowska-Lightowlers Z.M.A., Brooks C. MHC class I expression protects target cells from lysis by Ly49-deficient fetal NK cells. Eur J Immunol. 28:1998;47-56.
28. Dorfman J.R., Raulet D.H. Acquisition of Ly49 receptor expression by developing natural killer cells. J Exp Med. 187:1998;609-618.
29. Held W., Roland J., Raulet D.H. Allelic exclusion of Ly49 family genes encoding class I-MHC-specific receptors on NK cells. Nature. 376:1995;355-358.
30. Held W., Raulet D.H. Ly49A transgenic mice provide evidence for a major histocompatibility complex-dependent education process in natural killer cell development. J Exp Med. 185:1997;2079-2088.
31. Held W., Raulet D.H. Expression of the Ly49A gene in murine natural killer cell clones is predominantly but not exclusively mono-allelic. Eur J Immunol. 27:1997;2876-2884.
32. Held W., Kunz B. An allele-specific, stochastic gene expression process controls the expression of multiple Ly49 family genes and generates a diverse, MHC-specific NK cell receptor repertoire. Eur J Immunol. 28:1998;2407-2416.
33. Sentman C.L., Olsson M.Y., Kärre K. Missing self recognition by natural killer cells in MHC class I transgenic mice: a `receptor calibration model' for how effector cells adapt to self. Semin Immunol. 7:1995;109-119.