Electromotive versus passive diffusion of mitomycin C into human bladder wall: Concentration-depth profiles studies

Cancer Research

Volumn 59, Issue 19, 1999, Pages 4912-4918

  Di Stasi, Savino M ^a,e   Giannantoni, Antonella ^b   Massoud, Renato ^a   Dolci, Susanna ^a   Navarra, Pierluigi ^c   Vespasiani, Giuseppe ^a   Stephen, Robert L ^d  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b Santa Lucia Rehab Hosp Ist R   (Italy)

^c CATHOLIC UNIVERSITY   (Italy)

^d Physion Laboratories   (Italy)

^e NONE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MITOMYCIN C;

ARTICLE; BLADDER CANCER; BLADDER MUSCLE; BLADDER WALL; DRUG DIFFUSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LAMINA PROPRIA; MASS SPECTROMETRY; PASSIVE TRANSPORT; PRIORITY JOURNAL; UROTHELIUM;

BIOLOGICAL TRANSPORT; DIFFUSION; HUMANS; KINETICS; MITOMYCIN; MODELS, BIOLOGICAL; MUSCLE, SMOOTH; TIME FACTORS; URINARY BLADDER; UROTHELIUM;

EID: 0033215192     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Parkin, D. M., Pisani, P., Ferlay, J. Global cancer statistics. CA Cancer J. Clin., 49: 33-64, 1999.
2. Sobin, L. H., and Wittekind, C. (eds.), TNM Classification of Malignant Tumours, Ed. 5. New York: John Wiley and Sons, 1997.
3. Herr, H. W., Laudone, V. P., and Whitmore, W. F., Jr. An overview of intravesical therapy for superficial bladder tumors. J. Urol., 138: 1363-1368, 1987.
4. Lum, B. L., and Torti, F. M. Adjuvant intravesicular pharmacotherapy for superficial bladder cancer. J. Natl. Cancer Inst., 85: 682-694, 1991.
5. Lamm, D. L., Riggs, D. R., Traynelis, C. L., and Nseyo, U. O. Apparent failure of current intravesical chemotherapy prophylaxis to influence the long-term course of superficial transitional cell carcinoma of the bladder. J. Urol., 153: 1444-1450, 1995.
6. Dalton, J. T., Wientjes, M. G., Badalament, R. A., Drago, J. R., Au, J. L-S. Pharmacokinetics of intravesical mitomycin C in superficial bladder cancer patients. Cancer Res., 51: 5144-5152, 1991.
7. Wientjes, M. G., Dalton, J. T., Badalament, R. A., Drago, J. R., and Au, J. L-S. Bladder wall penetration of intravesical mitomycin C in dogs. Cancer Res., 51: 4347-4354, 1991.
8. Wientjes, M. G., Badalament, R. A., Wang, R. C., Hassan, F., and Au, J. L-S. Penetration of mitomycin C in human bladder. Cancer Res., 53: 3314-3320, 1993.
9. Schmittgen, T. D., Wientjes, M. G., Badalament, R. A., and Au, J. L-S. Pharmacodynamics of mitomycin C in cultured human bladder tumors. Cancer Res., 51: 3849-3856, 1991.
10. Bellantone, N. H., Rim, S., Francoeur, M. L., and Rosadi, B. Enhanced percutaneous absorption via iontophoresis. Evaluation of an in vitro system and transport of model compounds. Int. J. Pharm., 30: 63-72, 1986.
11. Banga, A. K., and Chien, Y. W. Iontophoretic delivery of drugs: fundamentals, developments and biomedical applications. J. Controlled Release, 7: 1-24, 1988.
12. Nightingale, E. R. Phenomenological theory of ion solvation. Effective radii of hydrated ions. J. Phys. Chem., 63: 1381-1387, 1959.
13. Di Stasi, S. M., Vespasiani, G., Giannantoni, A, Massoud, R., Dolci, S., and Micali F. Electromotive delivery of mitomycin C into human bladder wall. Cancer Res., 57: 875-880, 1997.
14. Brausi, M., Campo, B., Pizzocaro, G., Rigatti, P., Parma, A, Mazza, G., Vicini, A., and Stephen, R. L. Intravesical electromotive administration of drugs for treatment of superficial bladder cancer: a comparative Phase II study. Urology, 51: 506-509, 1998.
15. Riedl, C. R., Knoll, M., Plas, E., and Pfluger, H. Intravesical electromotive drug administration technique: preliminary results and side effects. J. Urol., 159: 1851-1856, 1998.
16. Di Stasi, S. M., Giannantoni, A., Massoud, R., Cortese, C., Vespasiani, G., and Micali, F. Electromotive administration of oxybutynin into the human bladder wall. J. Urol, 158: 228-233, 1997.
17. Wientjes, M. G., Dalton, J. T., Badalament, R. A., Dasani, B. M., Drago, J. R., and Au, J. L-S. A method to study drug concentration-depth profiles in tissues: mitomycin C in dogs bladder wall. Pharm. Res. (NY), 8: 168-173, 1991.
18. Connors, K. A., Amidon, G. L., and Stella, V. J. (eds.), Mitomycin C monograph. In: Chemical Stability of Pharmaceuticals, Ed. 2, pp 507-603. New York: John Wiley and Sons, 1986.
19. Cummings, J., Spanswick, V. J., and Smyth, J. F. Re-evaluation of the molecular pharmacology of mitomycin C. Eur. J. Cancer, 31A: 1928-1933, 1995.
20. Chirrey, L., Cummings, J., Halbert, G. W., and Smyth, J. F. Conversion of mitomycin C to 2,7-diaminomitosene and 10-decarbamoyl 2,7-diaminomitosene in tumour tissue in vivo. Cancer Chemother. Pharmacol., 35: 318-322, 1995.
21. Hicks, R. M., Ketterer, B., and Warren, R. C. The ultrastructure and chemistry of the luminal plasma membrane of the mammalian urinary bladder: a structure with low permeability to water and ions. Philos. Trans. R. Soc. Lond. B Biol. Sci., 268: 23-38, 1974.
22. Giddens, J. L., Sampson, H. A., Stephen, R. L., Beheshti, B., Sweet, J., and Jewett, M. A. S. Electromotive administration of mitoxantrone for localization of bladder cancer. Can. J. Urol., 5: 517, 1998.
23. Wientjes, M. G., Badalament, R. A., Au, J. L-S. Use of pharmacologic data and computer simulations to design an efficacy trial of intravesical mitomycin C therapy for superficial bladder cancer. Cancer Chemother. Pharmacol., 32: 255-262, 1993.
24. Witjes, J. A., Caris, C. T., Mungan, N. A., Debruyne, F. M., and Witjes, W. P. Results of a randomized Phase III trial of sequential intravesical therapy with mitomycin C and bacillus Calmette-Guérin versus mitomycin C alone in patients with superficial bladder cancer. J. Urol., 160: 1668-1671, 1998.
25. Stephen, R. L., Novak, J. M., Jensen, E. M., Kablitz, C., and Buys, S. S. Effect of osmotic pressure on uptake of chemotherapeutic agents by carcinoma cells. Cancer Res., 50: 4704-4708, 1990.
26. Jewett, M. A., Valiquette, L., Sampson, H. A., Katz, J., Fradet, Y., and Redelmeier, D. A. Electromotive drug administration of lidocaine as alternative anesthesia for transurethral surgery. J. Urol., 161: 482-485, 1999.