Genetic anticipation in idiopathic epilepsies;Anticipacion genetica en epilepsia idiopatica

Revista de Neurologia

Volumn 29, Issue 7, 1999, Pages 597-599

  Arcos Burgos, M ^a   Palacio, L G ^a   Sanchez J L ^a   Jimenez M E ^a   Mora, O ^a   Zuluaga, L ^a   Uribe, C S ^a   Lopez Gartner G ^a   Jimenez I ^a  

^a UNIVERSIDAD DE ANTIOQUIA   (Colombia)

Author keywords

Genetic anticipation; Genetic variability; Genetics of epilepsy; Idiopathic epilepsy; Unstable mutations

Indexed keywords

ARTICLE; ELECTROENCEPHALOGRAPHY; EPILEPSY; FEMALE; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PEDIGREE; RELATIVE; GENETIC PREDISPOSITION; GENETICS; QUESTIONNAIRE;

EPILEPSY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; QUESTIONNAIRES;

EID: 0033213216     PISSN: 02100010     EISSN: None     Source Type: Journal    
DOI: 10.33588/rn.2907.99262     Document Type: Article

References (16)

1. La Spada AR. Trinucleotid repeat instability: genetic features and molecular mechanisms. Brain Pathol 1997; 7: 943-63.
2. Koshy HY, Zoghbi HY. The CAG/polyglutamine tract diseases: gene products and molecular pathogenesis. Brain Pathol 1997; 7: 927-42.
3. Basset AS, Husted J. Anticipation or ascertainment bias in schizophrenia? Penrose's familial mental illness sample. Am J Hum Genet 1997; 60: 630-7.
4. Nance MA. Clinical aspects of CAG repeat diseases. Brain Pathol 1997; 7: 881-900.
5. Bittencourt PRM, Adamolekum B, Bharucha N, Carpio A, Cossio OH, Danesi MA, et al. ILAE commission report. Epilepsy in the tropics. I. Epidemiology, socioeconomic risk factors, and etiology. Epilepsia 1996; 37: 1121-7.
6. Bittencourt PRM, Adamolekum B, Bharucha N, Carpio A, Cossio OH, Danesi MA, et al. ILAE commission report. Epilepsy in the tropics. II. Clinical presentations, pathophysiology, immunologic diagnosis, economics, and therapy. Epilepsia 1996; 37: 1128-37.
7. Ottman R, Risch N, Hauser WA, Pedley TA, Lee JH, Barker-Cummings C, et al. Localization of a gene for partial epilepsy to chromosome 10q. Nat Genet 1995; 10: 56-60.
8. Serratosa JM, Delgado-Escueta AV, Medina MT, Zhang Q, Iranmanesh R, Sparkers RS. Clinical and genetic analysis of a large pedigree with juvenile myoclonic epilepsy. Ann Neurol 1996; 39: 187-95.
9. Zara F, Bianchi A, Avanzini G, Di-Donato S, Castellotti B, Patel PI, et al. Mapping of genes predisposing to idiopathic generalized epilepsy. Hum Mol Genet 1995; 4: 1201-7.
10. Liu AW, Delgado-Escueta AV, Serratosa JM, Alonso ME, Medina MT, Gee MN, et al. Juvenile myoclonic epilepsy locus in chromosome 6p21.2-p11: linkage to convulsions and electroencephalography trait. Am J Hum Genet 1995; 57: 368-81.
11. Greenberg DA, Durner M, Shinnar S. Association of HLA class II alleles in patients with juvenile myoclonic epilepsy compared with patients with other forms of adolescent-onset generalized epilepsy. Neurology 1996; 47: 750-5.
12. Jiménez I, Mora O, Jiménez M, Zuluaga L, Isaza R, Sánchez J, et al. Complex segregation analysis of non-myoclonic idiopathic generalized epilepsy in families ascertained from probands affected with idiopathic epilepsy with tonic-clonic seizures in Antioquia, Colombia. Hum Genet 1996; 98: 214-8.
13. Jiménez I, Mora O, López G, Jiménez ME, Zuluaga L, Isaza R, et al. Idiopathic epilepsy with generalized tonic clonic seizures in Antioquia, Colombia: Is the joint Amerindian and Negroid racial admixture the cause of its high prevalence? Biol Res 1996; 29: 297-304.
14. Arcos-Burgos M, Palacio LG, Jiménez I, Pineda N, Mora O, Sánchez JL, et al. Genealogías antioqueñas en las que la epilepsia idiopática presenta conglomeración familiar. Simulaciones de poder para detectar ligamiento genético. Acta Neurol Colomb 1997; 13: 69-75.
15. Jiménez I, Sánchez JL, Palacio LG, Jiménez ME, Mora O, López G, et al. Epilepsia idiopática: heterogeneidad v/s variación en la expresividad. Resultados del análisis de segregación compleja aplicados en epilepsias idiopáticas generalizadas y parciales. Acta Neurol Colomb. (In press).
16. Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989; 30: 389-9.